Valproic acid attenuates traumatic brain injury-induced inflammation in vivo: Involvement of autophagy and the Nrf2/ARE signaling pathway

Frontiers in Molecular Neuroscience

Volumn 11, Issue , 2018, Pages

  Chen, Xiangrong ^a,b   Wang, Handong ^a   Zhou, Mengliang ^a   Li, Xiang ^a   Fang, Zhongning ^b   Gao, Hongzhi ^b   Li, Yasong ^b   Hu, Weipeng ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; HDAC3; Inflammatory; Microglia; Nrf2 ARE pathway; Traumatic brain injury; Valproic acid

Indexed keywords

CASPASE 3; DICHLORODIHYDROFLUORESCEIN DIACETATE; HISTONE DEACETYLASE 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN EDEMA; BRAIN WATER; CELL ACTIVATION; CELL FRACTIONATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTONE ACETYLATION; IMMUNOFLUORESCENCE TEST; INFLAMMATION; LUCIFERASE ASSAY; MALE; MICROGLIA; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; TRAUMATIC BRAIN INJURY; TUNEL ASSAY; WESTERN BLOTTING;

EID: 85046893296     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2018.00117     Document Type: Article

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