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Volumn 88, Issue , 2016, Pages 433-446

Autophagy Inhibitor 3-MA Weakens Neuroprotective Effects of Posttraumatic Brain Injury Moderate Hypothermia

Author keywords

Apoptosis; Autophagy; Behavioral assessment; Moderate hypothermia; Traumatic brain injury

Indexed keywords

3 METHYLADENINE; BECLIN 1; CASPASE 3; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE;

EID: 84953272791     PISSN: 18788750     EISSN: 18788769     Source Type: Journal    
DOI: 10.1016/j.wneu.2015.10.055     Document Type: Article
Times cited : (22)

References (54)
  • 1
    • 84867217758 scopus 로고    scopus 로고
    • Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice
    • A. Ahmad, R. Crupi, D. Impellizzeri, M. Campolo, A. Marino, E. Esposito, and et al. Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice Brain Behav Immun 26 2012 1310 1321
    • (2012) Brain Behav Immun , vol.26 , pp. 1310-1321
    • Ahmad, A.1    Crupi, R.2    Impellizzeri, D.3    Campolo, M.4    Marino, A.5    Esposito, E.6
  • 4
    • 84903826557 scopus 로고    scopus 로고
    • MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat
    • F. Jia, Y.H. Yin, G.Y. Gao, Y. Wang, L. Cen, and J.Y. Jiang MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat J Neurotrauma 31 2014 1225 1234
    • (2014) J Neurotrauma , vol.31 , pp. 1225-1234
    • Jia, F.1    Yin, Y.H.2    Gao, G.Y.3    Wang, Y.4    Cen, L.5    Jiang, J.Y.6
  • 5
    • 0032749166 scopus 로고    scopus 로고
    • Neuronal death after brain injury. Models, mechanisms, and therapeutic strategies in vivo
    • P. Kermer, N. Klocker, and M. Bahr Neuronal death after brain injury. Models, mechanisms, and therapeutic strategies in vivo Cell Tissue Res 298 1999 383 395
    • (1999) Cell Tissue Res , vol.298 , pp. 383-395
    • Kermer, P.1    Klocker, N.2    Bahr, M.3
  • 6
    • 70749156375 scopus 로고    scopus 로고
    • Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact
    • M. Khan, Y.B. Im, A. Shunmugavel, A.G. Gilg, R.K. Dhindsa, A.K. Singh, and et al. Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact J Neuroinflammation 6 2009 32
    • (2009) J Neuroinflammation , vol.6 , pp. 32
    • Khan, M.1    Im, Y.B.2    Shunmugavel, A.3    Gilg, A.G.4    Dhindsa, R.K.5    Singh, A.K.6
  • 7
    • 77953026658 scopus 로고    scopus 로고
    • The up-regulation of voltage-gated sodium channel Nav1.6 expression following fluid percussion traumatic brain injury in rats
    • discussion: 9
    • Q. Mao, F. Jia, X.H. Zhang, Y.M. Qiu, J.W. Ge, W.J. Bao, and et al. The up-regulation of voltage-gated sodium channel Nav1.6 expression following fluid percussion traumatic brain injury in rats Neurosurgery 66 2010 1134 1139 discussion: 9
    • (2010) Neurosurgery , vol.66 , pp. 1134-1139
    • Mao, Q.1    Jia, F.2    Zhang, X.H.3    Qiu, Y.M.4    Ge, J.W.5    Bao, W.J.6
  • 9
    • 84934771449 scopus 로고    scopus 로고
    • Function and mechanisms of autophagy in brain and spinal cord trauma
    • M.M. Lipinski, J. Wu, A.I. Faden, and C. Sarkar Function and mechanisms of autophagy in brain and spinal cord trauma Antioxid Redox Signal 23 2015 565 577
    • (2015) Antioxid Redox Signal , vol.23 , pp. 565-577
    • Lipinski, M.M.1    Wu, J.2    Faden, A.I.3    Sarkar, C.4
  • 10
    • 84862257733 scopus 로고    scopus 로고
    • The crosstalk between autophagy and apoptosis: Where does this lead?
    • C. Gordy, and Y.W. He The crosstalk between autophagy and apoptosis: where does this lead? Protein Cell 3 2012 17 27
    • (2012) Protein Cell , vol.3 , pp. 17-27
    • Gordy, C.1    He, Y.W.2
  • 11
    • 79956011038 scopus 로고    scopus 로고
    • Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice
    • C.L. Luo, B.X. Li, Q.Q. Li, X.P. Chen, Y.X. Sun, H.J. Bao, and et al. Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice Neuroscience 184 2011 54 63
    • (2011) Neuroscience , vol.184 , pp. 54-63
    • Luo, C.L.1    Li, B.X.2    Li, Q.Q.3    Chen, X.P.4    Sun, Y.X.5    Bao, H.J.6
  • 13
    • 0029100471 scopus 로고
    • Posttraumatic brain hypothermia provides protection from sensorimotor and cognitive behavioral deficits
    • H.M. Bramlett, E.J. Green, W.D. Dietrich, R. Busto, M.Y. Globus, and M.D. Ginsberg Posttraumatic brain hypothermia provides protection from sensorimotor and cognitive behavioral deficits J Neurotrauma 12 1995 289 298
    • (1995) J Neurotrauma , vol.12 , pp. 289-298
    • Bramlett, H.M.1    Green, E.J.2    Dietrich, W.D.3    Busto, R.4    Globus, M.Y.5    Ginsberg, M.D.6
  • 14
    • 33947667826 scopus 로고    scopus 로고
    • Therapeutic effect of hypothermia and dizocilpine maleate on traumatic brain injury in neonatal rats
    • S.E. Celik, H. Ozturk, and S. Tolunay Therapeutic effect of hypothermia and dizocilpine maleate on traumatic brain injury in neonatal rats J Neurotrauma 23 2006 1355 1365
    • (2006) J Neurotrauma , vol.23 , pp. 1355-1365
    • Celik, S.E.1    Ozturk, H.2    Tolunay, S.3
  • 15
    • 0031933403 scopus 로고    scopus 로고
    • Protective effects of moderate hypothermia on behavioral deficits but not necrotic cavitation following cortical impact injury in the rat
    • C.E. Dixon, C.G. Markgraf, F. Angileri, B.R. Pike, B. Wolfson, J.K. Newcomb, and et al. Protective effects of moderate hypothermia on behavioral deficits but not necrotic cavitation following cortical impact injury in the rat J Neurotrauma 15 1998 95 103
    • (1998) J Neurotrauma , vol.15 , pp. 95-103
    • Dixon, C.E.1    Markgraf, C.G.2    Angileri, F.3    Pike, B.R.4    Wolfson, B.5    Newcomb, J.K.6
  • 16
    • 60749117577 scopus 로고    scopus 로고
    • Effect of post-traumatic mild hypothermia on hippocampal cell death after traumatic brain injury in rats
    • F. Jia, Q. Mao, Y.M. Liang, and J.Y. Jiang Effect of post-traumatic mild hypothermia on hippocampal cell death after traumatic brain injury in rats J Neurotrauma 26 2009 243 252
    • (2009) J Neurotrauma , vol.26 , pp. 243-252
    • Jia, F.1    Mao, Q.2    Liang, Y.M.3    Jiang, J.Y.4
  • 17
    • 84893948681 scopus 로고    scopus 로고
    • The effect of hypothermia on the expression of TIMP-3 after traumatic brain injury in rats
    • F. Jia, Q. Mao, Y.M. Liang, and J.Y. Jiang The effect of hypothermia on the expression of TIMP-3 after traumatic brain injury in rats J Neurotrauma 31 2014 387 394
    • (2014) J Neurotrauma , vol.31 , pp. 387-394
    • Jia, F.1    Mao, Q.2    Liang, Y.M.3    Jiang, J.Y.4
  • 18
    • 62649175862 scopus 로고    scopus 로고
    • Clinical study of mild hypothermia treatment for severe traumatic brain injury
    • J.Y. Jiang Clinical study of mild hypothermia treatment for severe traumatic brain injury J Neurotrauma 26 2009 399 406
    • (2009) J Neurotrauma , vol.26 , pp. 399-406
    • Jiang, J.Y.1
  • 19
    • 84938739694 scopus 로고    scopus 로고
    • Attenuation of cell death in injured cortex following post-traumatic brain injury moderate hypothermia: Possible involvement of autophagy pathway
    • Y. Jin, Y. Lin, J.F. Feng, F. Jia, G. Gao, and J.Y. Jiang Attenuation of cell death in injured cortex following post-traumatic brain injury moderate hypothermia: possible involvement of autophagy pathway World Neurosurg 84 2015 420 430
    • (2015) World Neurosurg , vol.84 , pp. 420-430
    • Jin, Y.1    Lin, Y.2    Feng, J.F.3    Jia, F.4    Gao, G.5    Jiang, J.Y.6
  • 20
    • 84934287297 scopus 로고    scopus 로고
    • Moderate hypothermia significantly decreases hippocampal cell death involving autophagy pathway after moderate traumatic brain injury
    • Y. Jin, Y. Lin, J.F. Feng, F. Jia, G.Y. Gao, and J.Y. Jiang Moderate hypothermia significantly decreases hippocampal cell death involving autophagy pathway after moderate traumatic brain injury J Neurotrauma 32 2015 1090 1100
    • (2015) J Neurotrauma , vol.32 , pp. 1090-1100
    • Jin, Y.1    Lin, Y.2    Feng, J.F.3    Jia, F.4    Gao, G.Y.5    Jiang, J.Y.6
  • 21
    • 84893907464 scopus 로고    scopus 로고
    • Blockage of the upregulation of voltage-gated sodium channel nav1.3 improves outcomes after experimental traumatic brain injury
    • X.J. Huang, W.P. Li, Y. Lin, J.F. Feng, F. Jia, Q. Mao, and et al. Blockage of the upregulation of voltage-gated sodium channel nav1.3 improves outcomes after experimental traumatic brain injury J Neurotrauma 31 2014 346 357
    • (2014) J Neurotrauma , vol.31 , pp. 346-357
    • Huang, X.J.1    Li, W.P.2    Lin, Y.3    Feng, J.F.4    Jia, F.5    Mao, Q.6
  • 23
    • 0024493996 scopus 로고
    • Traumatic brain injury in the rat: Characterization of a lateral fluid-percussion model
    • T.K. McIntosh, R. Vink, L. Noble, I. Yamakami, S. Fernyak, H. Soares, and et al. Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model Neuroscience 28 1989 233 244
    • (1989) Neuroscience , vol.28 , pp. 233-244
    • McIntosh, T.K.1    Vink, R.2    Noble, L.3    Yamakami, I.4    Fernyak, S.5    Soares, H.6
  • 24
    • 0019993349 scopus 로고
    • Amphetamine, haloperidol, and experience interact to affect rate of recovery after motor cortex injury
    • D.M. Feeney, A. Gonzalez, and W.A. Law Amphetamine, haloperidol, and experience interact to affect rate of recovery after motor cortex injury Science 217 1982 855 857
    • (1982) Science , vol.217 , pp. 855-857
    • Feeney, D.M.1    Gonzalez, A.2    Law, W.A.3
  • 25
    • 0026521269 scopus 로고
    • Cognitive deficits following traumatic brain injury produced by controlled cortical impact
    • R.J. Hamm, C.E. Dixon, D.M. Gbadebo, A.K. Singha, L.W. Jenkins, B.G. Lyeth, and et al. Cognitive deficits following traumatic brain injury produced by controlled cortical impact J Neurotrauma 9 1992 11 20
    • (1992) J Neurotrauma , vol.9 , pp. 11-20
    • Hamm, R.J.1    Dixon, C.E.2    Gbadebo, D.M.3    Singha, A.K.4    Jenkins, L.W.5    Lyeth, B.G.6
  • 26
    • 0036121894 scopus 로고    scopus 로고
    • Attenuation of working memory and spatial acquisition deficits after a delayed and chronic bromocriptine treatment regimen in rats subjected to traumatic brain injury by controlled cortical impact
    • A.E. Kline, J.L. Massucci, D.W. Marion, and C.E. Dixon Attenuation of working memory and spatial acquisition deficits after a delayed and chronic bromocriptine treatment regimen in rats subjected to traumatic brain injury by controlled cortical impact J Neurotrauma 19 2002 415 425
    • (2002) J Neurotrauma , vol.19 , pp. 415-425
    • Kline, A.E.1    Massucci, J.L.2    Marion, D.W.3    Dixon, C.E.4
  • 27
    • 78649350758 scopus 로고    scopus 로고
    • Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury
    • A.E. Kline, R.L. McAloon, K.A. Henderson, U.K. Bansal, B.M. Ganti, R.H. Ahmed, and et al. Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury J Neurotrauma 27 2010 2021 2032
    • (2010) J Neurotrauma , vol.27 , pp. 2021-2032
    • Kline, A.E.1    McAloon, R.L.2    Henderson, K.A.3    Bansal, U.K.4    Ganti, B.M.5    Ahmed, R.H.6
  • 28
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • R. Morris Developments of a water-maze procedure for studying spatial learning in the rat J Neurosci Methods 11 1984 47 60
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 29
    • 0030820401 scopus 로고    scopus 로고
    • Morris water maze deficits in rats following traumatic brain injury: Lateral controlled cortical impact
    • S.W. Scheff, S.A. Baldwin, R.W. Brown, and P.J. Kraemer Morris water maze deficits in rats following traumatic brain injury: lateral controlled cortical impact J Neurotrauma 14 1997 615 627
    • (1997) J Neurotrauma , vol.14 , pp. 615-627
    • Scheff, S.W.1    Baldwin, S.A.2    Brown, R.W.3    Kraemer, P.J.4
  • 30
    • 0033782260 scopus 로고    scopus 로고
    • Caspase pathways, neuronal apoptosis, and CNS injury
    • B.A. Eldadah, and A.I. Faden Caspase pathways, neuronal apoptosis, and CNS injury J Neurotrauma 17 2000 811 829
    • (2000) J Neurotrauma , vol.17 , pp. 811-829
    • Eldadah, B.A.1    Faden, A.I.2
  • 31
    • 34547689505 scopus 로고    scopus 로고
    • Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1
    • W. Feng, S. Huang, H. Wu, and M. Zhang Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1 J Mol Biol 372 2007 223 235
    • (2007) J Mol Biol , vol.372 , pp. 223-235
    • Feng, W.1    Huang, S.2    Wu, H.3    Zhang, M.4
  • 32
    • 80052093009 scopus 로고    scopus 로고
    • Therapeutic hypothermia: Benefits, mechanisms and potential clinical applications in neurological, cardiac and kidney injury
    • E.M. Moore, A.D. Nichol, S.A. Bernard, and R. Bellomo Therapeutic hypothermia: benefits, mechanisms and potential clinical applications in neurological, cardiac and kidney injury Injury 42 2011 843 854
    • (2011) Injury , vol.42 , pp. 843-854
    • Moore, E.M.1    Nichol, A.D.2    Bernard, S.A.3    Bellomo, R.4
  • 33
    • 67650303102 scopus 로고    scopus 로고
    • Mechanisms of action, physiological effects, and complications of hypothermia
    • K.H. Polderman Mechanisms of action, physiological effects, and complications of hypothermia Crit Care Med 37 2009 S186 202
    • (2009) Crit Care Med , vol.37 , pp. S186-202
    • Polderman, K.H.1
  • 34
    • 84870501216 scopus 로고    scopus 로고
    • Therapeutic hypothermia for traumatic brain injury
    • L.A. Urbano, and M. Oddo Therapeutic hypothermia for traumatic brain injury Curr Neurol Neurosci Rep 12 2012 580 591
    • (2012) Curr Neurol Neurosci Rep , vol.12 , pp. 580-591
    • Urbano, L.A.1    Oddo, M.2
  • 35
    • 34250894388 scopus 로고    scopus 로고
    • BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)
    • M.C. Maiuri, A. Criollo, E. Tasdemir, J.M. Vicencio, N. Tajeddine, J.A. Hickman, and et al. BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L) Autophagy 3 2007 374 376
    • (2007) Autophagy , vol.3 , pp. 374-376
    • Maiuri, M.C.1    Criollo, A.2    Tasdemir, E.3    Vicencio, J.M.4    Tajeddine, N.5    Hickman, J.A.6
  • 37
    • 20344402819 scopus 로고    scopus 로고
    • Autophagy and intracellular surveillance: Modulating MHC class II antigen presentation with stress
    • V.L. Crotzer, and J.S. Blum Autophagy and intracellular surveillance: modulating MHC class II antigen presentation with stress Proc Natl Acad Sci U S A 102 2005 7779 7780
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7779-7780
    • Crotzer, V.L.1    Blum, J.S.2
  • 38
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Y. Kabeya, N. Mizushima, T. Ueno, A. Yamamoto, T. Kirisako, T. Noda, and et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing EMBO J 19 2000 5720 5728
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 39
    • 38049064882 scopus 로고    scopus 로고
    • Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness
    • R.S. Clark, H. Bayir, C.T. Chu, S.M. Alber, P.M. Kochanek, and S.C. Watkins Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness Autophagy 4 2008 88 90
    • (2008) Autophagy , vol.4 , pp. 88-90
    • Clark, R.S.1    Bayir, H.2    Chu, C.T.3    Alber, S.M.4    Kochanek, P.M.5    Watkins, S.C.6
  • 40
    • 0035032723 scopus 로고    scopus 로고
    • Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
    • A. Kihara, Y. Kabeya, Y. Ohsumi, and T. Yoshimori Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network EMBO Rep 2 2001 330 335
    • (2001) EMBO Rep , vol.2 , pp. 330-335
    • Kihara, A.1    Kabeya, Y.2    Ohsumi, Y.3    Yoshimori, T.4
  • 41
    • 84872845688 scopus 로고    scopus 로고
    • The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes
    • B.L. Heckmann, X. Yang, X. Zhang, and J. Liu The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes Br J Pharmacol 168 2013 163 171
    • (2013) Br J Pharmacol , vol.168 , pp. 163-171
    • Heckmann, B.L.1    Yang, X.2    Zhang, X.3    Liu, J.4
  • 42
    • 39449093070 scopus 로고    scopus 로고
    • Caspase activation cascades in apoptosis
    • S.E. Logue, and S.J. Martin Caspase activation cascades in apoptosis Biochem Soc Trans 36 2008 1 9
    • (2008) Biochem Soc Trans , vol.36 , pp. 1-9
    • Logue, S.E.1    Martin, S.J.2
  • 43
    • 77957773834 scopus 로고    scopus 로고
    • Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis
    • C. Zhou, X. Li, W. Du, Y. Feng, X. Kong, Y. Li, and et al. Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis Chemotherapy 56 2010 393 402
    • (2010) Chemotherapy , vol.56 , pp. 393-402
    • Zhou, C.1    Li, X.2    Du, W.3    Feng, Y.4    Kong, X.5    Li, Y.6
  • 44
    • 76349098949 scopus 로고    scopus 로고
    • Crosstalk between apoptosis and autophagy within the Beclin 1 interactome
    • M.C. Maiuri, A. Criollo, and G. Kroemer Crosstalk between apoptosis and autophagy within the Beclin 1 interactome EMBO J 29 2010 515 516
    • (2010) EMBO J , vol.29 , pp. 515-516
    • Maiuri, M.C.1    Criollo, A.2    Kroemer, G.3
  • 45
    • 38049115875 scopus 로고    scopus 로고
    • Apoptosis and autophagy: Regulatory connections between two supposedly different processes
    • A. Thorburn Apoptosis and autophagy: regulatory connections between two supposedly different processes Apoptosis 13 2008 1 9
    • (2008) Apoptosis , vol.13 , pp. 1-9
    • Thorburn, A.1
  • 46
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • B. Levine, and G. Kroemer Autophagy in the pathogenesis of disease Cell 132 2008 27 42
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 47
    • 34248998801 scopus 로고    scopus 로고
    • Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
    • M.C. Maiuri, G. Le Toumelin, A. Criollo, J.C. Rain, F. Gautier, P. Juin, and et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1 EMBO J 26 2007 2527 2539
    • (2007) EMBO J , vol.26 , pp. 2527-2539
    • Maiuri, M.C.1    Le Toumelin, G.2    Criollo, A.3    Rain, J.C.4    Gautier, F.5    Juin, P.6
  • 48
    • 34249037565 scopus 로고    scopus 로고
    • Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
    • A. Oberstein, P.D. Jeffrey, and Y. Shi Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein J Biol Chem 282 2007 13123 13132
    • (2007) J Biol Chem , vol.282 , pp. 13123-13132
    • Oberstein, A.1    Jeffrey, P.D.2    Shi, Y.3
  • 49
    • 44949237240 scopus 로고    scopus 로고
    • JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
    • Y. Wei, S. Pattingre, S. Sinha, M. Bassik, and B. Levine JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy Mol Cell 30 2008 678 688
    • (2008) Mol Cell , vol.30 , pp. 678-688
    • Wei, Y.1    Pattingre, S.2    Sinha, S.3    Bassik, M.4    Levine, B.5
  • 50
    • 48949116105 scopus 로고    scopus 로고
    • Changes in autophagy proteins in a rat model of controlled cortical impact induced brain injury
    • S. Sadasivan, W.A. Dunn Jr., R.L. Hayes, and K.K. Wang Changes in autophagy proteins in a rat model of controlled cortical impact induced brain injury Biochem Biophys Res Commun 373 2008 478 481
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 478-481
    • Sadasivan, S.1    Dunn, W.A.2    Hayes, R.L.3    Wang, K.K.4
  • 51
    • 67349232611 scopus 로고    scopus 로고
    • Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function
    • I.A. Ciechomska, G.C. Goemans, J.N. Skepper, and A.M. Tolkovsky Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function Oncogene 28 2009 2128 2141
    • (2009) Oncogene , vol.28 , pp. 2128-2141
    • Ciechomska, I.A.1    Goemans, G.C.2    Skepper, J.N.3    Tolkovsky, A.M.4
  • 52
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • S. Pattingre, A. Tassa, X. Qu, R. Garuti, X.H. Liang, N. Mizushima, and et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy Cell 122 2005 927 939
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 53
    • 0036209260 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release
    • D. Liu, C. Lu, R. Wan, W.W. Auyeung, and M.P. Mattson Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release J Cereb Blood Flow Metab 22 2002 431 443
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 431-443
    • Liu, D.1    Lu, C.2    Wan, R.3    Auyeung, W.W.4    Mattson, M.P.5
  • 54
    • 69449089542 scopus 로고    scopus 로고
    • Why doesn't Beclin 1, a BH3-only protein, suppress the anti-apoptotic function of Bcl-2?
    • I.A. Ciechomska, C.G. Goemans, and A.M. Tolkovsky Why doesn't Beclin 1, a BH3-only protein, suppress the anti-apoptotic function of Bcl-2? Autophagy 5 2009 880 881
    • (2009) Autophagy , vol.5 , pp. 880-881
    • Ciechomska, I.A.1    Goemans, C.G.2    Tolkovsky, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.