Correction: SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling (Journal of Experimental Medicine (2018) 215:5 DOI: 10.1084/jem.20171477);SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-ß signaling

Journal of Experimental Medicine

Volumn 215, Issue 5, 2018, Pages 1337-1347

  Jiang, Linjia ^a   Han, Xue ^a,c   Wang, Jin ^a,b,c,e   Wang, Chen ^b,c   Sun, Xiaoqiang ^c   Xie, Jiayi ^a,c   Wu, Guojin ^d   Phan, Hiep ^d   Liu, Zhenguo ^b   Zhang, Cheng Cheng ^d   Zhao, Meng ^a,c   Kang, Xunlei ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b University of Missouri   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE SHP 1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; PROTEIN BINDING; PTPN6 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL QUIESCENCE; CELLULAR PARAMETERS; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL SELF-RENEWAL; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CELL SELF-RENEWAL; CHEMISTRY; CYTOLOGY; METABOLISM; STEM CELL NICHE; TIME FACTOR;

AMINO ACID SEQUENCE; ANIMALS; CELL SELF RENEWAL; HEMATOPOIETIC STEM CELLS; MICE, INBRED C57BL; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; STEM CELL NICHE; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 85046831669     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.2017147706252018c     Document Type: Erratum

References (45)

1. Billadeau, D.D., and P.J. Leibson. 2002. ITAMs versus ITIMs: striking a balance during cell regulation. J. Clin. Invest. 109:161-168. https:// doi .org/ 10 .1172/ JCI0214843
2. Blank, U., and S. Karlsson. 2015. TGF-ß signaling in the control of hematopoietic stem cells. Blood. 125:3542-3550. https:// doi .org/ 10 .1182/ blood -2014 -12 -618090
3. Blank, U., G. Karlsson, J.L. Moody, T. Utsugisawa, M. Magnusson, S. Singbrant, J. Larsson, and S. Karlsson. 2006. Smad7 promotes self-renewal of hematopoietic stem cells. Blood. 108:4246-4254. https:// doi .org/ 10 .1182/ blood -2006 -02 -005611
4. Bruns, I., D. Lucas, S. Pinho, J. Ahmed, M.P. Lambert, Y. Kunisaki, C. Scheiermann, L. Schiff, M. Poncz, A. Bergman, and P.S. Frenette. 2014. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat. Med. 20:1315-1320. https:// doi .org/ 10 .1038/ nm .3707
5. Chen, Z., S. Shojaee, M. Buchner, H. Geng, J.W. Lee, L. Klemm, B. Titz, T.G. Graeber, E. Park, Y.X. Tan, et al. 2015. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 521:357-361. https:// doi .org/ 10 .1038/ nature14231
6. Göthert, J.R., S.E. Gustin, M.A. Hall, A.R. Green, B. Göttgens, D.J. Izon, and C.G. Begley. 2005. In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis. Blood. 105:2724-2732. https:// doi .org/ 10 .1182/ blood -2004 -08 -3037
7. Hu, Y., and G.K. Smyth. 2009. ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. J. Immunol. Methods. 347:70-78. https:// doi .org/ 10 .1016/ j .jim .2009 .06 .008
8. Huynh, H., J. Zheng, M. Umikawa, C. Zhang, R. Silvany, S. Iizuka, M. Holzenberger, W. Zhang, and C.C. Zhang. 2011. IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells. Blood. 118:3236- 3243. https:// doi .org/ 10 .1182/ blood -2011 -01 -331876
9. Itkin, T., S. Gur-Cohen, J.A. Spencer, A. Schajnovitz, S.K. Ramasamy, A.P. Kusumbe, G. Ledergor, Y. Jung, I. Milo, M.G. Poulos, et al. 2016. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. 532:323-328. https:// doi .org/ 10 .1038/ nature17624
10. Jiao, H., W. Yang, K. Berrada, M. Tabrizi, L. Shultz, and T. Yi. 1997. Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: detection of potential HCP substrates in GM-CSF signal transduction. Exp. Hematol. 25:592-600.
11. Kaneko, T., Y. Saito, T. Kotani, H. Okazawa, H. Iwamura, M. Sato-Hashimoto, Y. Kanazawa, S. Takahashi, K. Hiromura, S. Kusakari, et al. 2012. Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity. J. Immunol. 188:5397-5407. https:// doi .org/ 10 .4049/ jimmunol .1103210
12. Kang, X., Z. Lu, C. Cui, M. Deng, Y. Fan, B. Dong, X. Han, F. Xie, J.W. Tyner, J.E. Coligan, et al. 2015. The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. Nat. Cell Biol. 17:665-677. https:// doi .org/ 10 .1038/ ncb3158
13. Kang, X., J. Kim, M. Deng, S. John, H. Chen, G. Wu, H. Phan, and C.C. Zhang. 2016. Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors. Cell Cycle. 15:25-40. https:// doi .org/ 10 .1080/ 15384101 .2015 .1121324
14. Kunisaki, Y., I. Bruns, C. Scheiermann, J. Ahmed, S. Pinho, D. Zhang, T. Mizoguchi, Q. Wei, D. Lucas, K. Ito, et al. 2013. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature. 502:637-643. https:// doi .org/ 10 .1038/ nature12612
15. Larsson, J., U. Blank, H. Helgadottir, J.M. Björnsson, M. Ehinger, M.J. Goumans, X. Fan, P. Levéen, and S. Karlsson. 2003. TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro. Blood. 102:3129-3135. https:// doi .org/ 10 .1182/ blood -2003 -04 -1300
16. Long, E.O. 1999. Regulation of immune responses through inhibitory receptors. Annu. Rev. Immunol. 17:875-904. https:// doi .org/ 10 .1146/ annurev .immunol .17 .1 .875
17. Lorenz, U. 2009. SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels. Immunol. Rev. 228:342-359. https:// doi .org/ 10 .1111/ j .1600 -065X .2008 .00760 .x
18. Lorenz, U., A.D. Bergemann, H.N. Steinberg, J.G. Flanagan, X. Li, S.J. Galli, and B.G. Neel. 1996. Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase SHP1. J. Exp. Med. 184:1111-1126. https:// doi .org/ 10 .1084/ jem .184 .3 .1111
19. Mazharian, A., J. Mori, Y.J. Wang, S. Heising, B.G. Neel, S.P. Watson, and Y.A. Senis. 2013. Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function. Blood. 121:4205-4220. https:// doi .org/ 10 .1182/ blood -2012 -08 -449272
20. Nakamura-Ishizu, A., K. Takubo, H. Kobayashi, K. Suzuki-Inoue, and T. Suda. 2015. CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. J. Exp. Med. 212:2133-2146. https:// doi .org/ 10 .1084/ jem .20150057
21. Neel, B.G., H. Gu, and L. Pao. 2003. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 28:284-293. https:// doi .org/ 10 .1016/ S0968 -0004(03)00091 -4
22. Pao, L.I., K.P. Lam, J.M. Henderson, J.L. Kutok, M. Alimzhanov, L. Nitschke, M.L. Thomas, B.G. Neel, and K. Rajewsky. 2007. B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity. 27:35-48. https:// doi .org/ 10 .1016/ j .immuni .2007 .04 .016
23. Park, S.M., R.P. Deering, Y. Lu, P. Tivnan, S. Lianoglou, F. Al-Shahrour, B.L. Ebert, N. Hacohen, C. Leslie, G.Q. Daley, et al. 2014. Musashi-2 controls cell fate, lineage bias, and TGF-ß signaling in HSCs. J. Exp. Med. 211:71-87. https:// doi .org/ 10 .1084/ jem .20130736
24. Paulson, R.F., S. Vesely, K.A. Siminovitch, and A. Bernstein. 1996. Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1. Nat. Genet. 13:309-315. https:// doi .org/ 10 .1038/ ng0796 -309
25. Sacchetti, B., A. Funari, S. Michienzi, S. Di Cesare, S. Piersanti, I. Saggio, E. Tagliafico, S. Ferrari, P.G. Robey, M. Riminucci, and P. Bianco. 2007. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell. 131:324-336. https:// doi .org/ 10 .1016/ j .cell .2007 .08 .025
26. Scandura, J.M., P. Boccuni, J. Massagué, and S.D. Nimer. 2004. Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proc. Natl. Acad. Sci. USA. 101:15231-15236. https:// doi .org/ 10 .1073/ pnas .0406771101
27. Schlichter, L.C., J. Jiang, J. Wang, E.W. Newell, F.W. Tsui, and D. Lam. 2014. Regulation of hERG and hEAG channels by Src and by SHP-1 tyrosine phosphatase via an ITIM region in the cyclic nucleotide binding domain. PLoS One. 9:e90024. https:// doi .org/ 10 .1371/ journal .pone .0090024
28. Stadtmann, A., H. Block, S. Volmering, C. Abram, C. Sohlbach, M. Boras, C.A. Lowell, and A. Zarbock. 2015. Cross-Talk between Shp1 and PIP KIγ Controls Leukocyte Recruitment. J. Immunol. 195:1152-1161. https:// doi .org/ 10 .4049/ jimmunol .1500606
29. Staub, E., A. Rosenthal, and B. Hinzmann. 2004. Systematic identification of immunoreceptor tyrosine-based inhibitory motifs in the human proteome. Cell. Signal. 16:435-456. https:// doi .org/ 10 .1016/ j .cellsig .2003 .08 .013
30. Stromnes, I.M., C. Fowler, C.C. Casamina, C.M. Georgopolos, M.S. McAfee, T.M. Schmitt, X. Tan, T.D. Kim, I. Choi, J.N. Blattman, and P.D. Greenberg. 2012. Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo. J. Immunol. 189:1812-1825. https:// doi .org/ 10 .4049/ jimmunol .1200552
31. Tapley, P., N.K. Shevde, P.A. Schweitzer, M. Gallina, S.W. Christianson, I.L. Lin, R.B. Stein, L.D. Shultz, J. Rosen, and P. Lamb. 1997. Increased G-CSF responsiveness of bone marrow cells from hematopoietic cell phosphatase deficient viable motheaten mice. Exp. Hematol. 25:122-131.
32. Tibaldi, E., A.M. Brunati, F. Zonta, F. Frezzato, C. Gattazzo, R. Zambello, E. Gringeri, G. Semenzato, M.A. Pagano, and L. Trentin. 2011. Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells. Leukemia. 25:1768-1781. https:// doi .org/ 10 .1038/ leu .2011 .152
33. Tiedt, R., T. Schomber, H. Hao-Shen, and R.C. Skoda. 2007. Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo. Blood. 109:1503- 1506. https:// doi .org/ 10 .1182/ blood -2006 -04 -020362
34. Viant, C., A. Fenis, G. Chicanne, B. Payrastre, S. Ugolini, and E. Vivier. 2014. SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells. Nat. Commun. 5:5108. https:// doi .org/ 10 .1038/ ncomms6108
35. Wilson, A., E. Laurenti, G. Oser, R.C. van der Wath, W. Blanco-Bose, M. Jaworski, S. Offner, C.F. Dunant, L. Eshkind, E. Bockamp, et al. 2008. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell. 135:1118-1129. https:// doi .org/ 10 .1016/ j .cell .2008 .10 .048
36. Wu, C., Q. Guan, Y. Wang, Z.J. Zhao, and G.W. Zhou. 2003a. SHP-1 suppresses cancer cell growth by promoting degradation of JAK kinases. J. Cell. Biochem. 90:1026-1037. https:// doi .org/ 10 .1002/ jcb .10727
37. Wu, C., M. Sun, L. Liu, and G.W. Zhou. 2003b. The function of the protein tyrosine phosphatase SHP-1 in cancer. Gene. 306:1-12. https:// doi .org/ 10 .1016/ S0378 -1119(03)00400 -1
38. Xiao, W., T. Ando, H.Y. Wang, Y. Kawakami, and T. Kawakami. 2010. Lynand PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease. Blood. 116:6003-6013. https:// doi .org/ 10 .1182/ blood -2010 -05 -283937
39. Yamazaki, S., A. Iwama, S. Takayanagi, Y. Morita, K. Eto, H. Ema, and H. Nakauchi. 2006. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 25:3515-3523. https:// doi .org/ 10 .1038/ sj .emboj .7601236
40. Yamazaki, S., A. Iwama, S. Takayanagi, K. Eto, H. Ema, and H. Nakauchi. 2009. TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Blood. 113:1250-1256. https:// doi .org/ 10 .1182/ blood -2008 -04 -146480
41. Yamazaki, S., H. Ema, G. Karlsson, T. Yamaguchi, H. Miyoshi, S. Shioda, M.M. Taketo, S. Karlsson, A. Iwama, and H. Nakauchi. 2011. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell. 147:1146-1158. https:// doi .org/ 10 .1016/ j .cell .2011 .09 .053
42. Zhao, M., J.M. Perry, H. Marshall, A. Venkatraman, P. Qian, X.C. He, J. Ahamed, and L. Li. 2014. Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells. Nat. Med. 20:1321-1326. https:// doi .org/ 10 .1038/ nm .3706
43. Zheng, J., H. Huynh, M. Umikawa, R. Silvany, and C.C. Zhang. 2011a. Angiopoietin- like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche. Blood. 117:470-479. https:// doi .org/ 10 .1182/ blood -2010 -06 -291716
44. Zheng, J., M. Umikawa, S. Zhang, H. Huynh, R. Silvany, B.P. Chen, L. Chen, and C.C. Zhang. 2011b. Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation. Cell Stem Cell. 9:119-130. https:// doi .org/ 10 .1016/ j .stem .2011 .06 .003
45. Zheng, J., M. Umikawa, C. Cui, J. Li, X. Chen, C. Zhang, H. Huynh, X. Kang, R. Silvany, X. Wan, et al. 2012. Inhibitory receptors bind ANG PTLs and support blood stem cells and leukaemia development. Nature. 485:656-660. https:// doi .org/ 10 .1038/ nature11095