An Immunocompetent Mouse Model of Zika Virus Infection

Cell Host and Microbe

Volumn 23, Issue 5, 2018, Pages 672-685.e6

  Gorman, Matthew J ^a   Caine, Elizabeth A ^a   Zaitsev, Konstantin ^a,h   Begley, Matthew C ^b,c   Weger Lucarelli, James ^d   Uccellini, Melissa B ^e   Tripathi, Shashank ^e   Morrison, Juliet ^e   Yount, Boyd L ^b,c   Dinnon, Kenneth H ^b,c   Rückert, Claudia ^d   Young, Michael C ^d   Zhu, Zhe ^f   Robertson, Shelly J ^g   McNally, Kristin L ^g   Ye, Jing ^a   Cao, Bin ^a   Mysorekar, Indira U ^a   Ebel, Gregory D ^d   Baric, Ralph S ^b,c   Best, Sonja M ^g   Artyomov, Maxim N ^a   Garcia Sastre, Adolfo ^e   Diamond, Michael S ^a   more..

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c University of North Carolina at Chapel Hill   (United States)

^d Veterinary Dentistry and Oral Surgery   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g NATIONAL INSTITUTES OF HEALTH   (United States)

^h ITMO UNIVERSITY   (Russian Federation)

Author keywords

flavivirus; immunity; infectious clone; interferon; pathogenesis; pregnancy; RNA sequencing; transgenic mice; vertical transmission; Zika virus

Indexed keywords

ARGININE; LYSINE; RAG1 PROTEIN; STAT2 PROTEIN; VIRUS RNA; ALPHA BETA INTERFERON RECEPTOR; BETA INTERFERON; HOMEODOMAIN PROTEIN; IFNAR1 PROTEIN, MOUSE; INTERFERON; NS3 PROTEIN, FLAVIVIRUS; NS4B PROTEIN, FLAVIVIRUS; RAG-1 PROTEIN; RNA HELICASE; SERINE PROTEINASE; VIRAL PROTEIN;

ADULT; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BLOOD BRAIN BARRIER; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; EXON; GENE EXPRESSION; HOMOLOGOUS RECOMBINATION; HOST RESISTANCE; IMMUNE DEFICIENCY; INNATE IMMUNITY; MESENCEPHALON; MOUSE; NEXT GENERATION SEQUENCING; NONHUMAN; PATHOGENICITY; PLACENTAL TRANSFER; RNA SEQUENCE; T LYMPHOCYTE; VERO CELL LINE; VIRUS STRAIN; ZIKA FEVER; ZIKA VIRUS; ZIKA VIRUS DAK 41525; ANIMAL; BRAIN; C57BL MOUSE; DISEASE MODEL; FEMALE; FETUS DISEASE; GENETICS; HUMAN; IMMUNITY; IMMUNOLOGY; METABOLISM; MUTATION; PLACENTA; PREGNANCY; PREGNANCY COMPLICATION; TRANSGENIC MOUSE; VERTICAL TRANSMISSION; VIROLOGY;

ANIMALS; BRAIN; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FEMALE; FETAL DISEASES; HOMEODOMAIN PROTEINS; HUMANS; IMMUNITY; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; INTERFERON-BETA; INTERFERONS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RECEPTOR, INTERFERON ALPHA-BETA; RNA HELICASES; SERINE ENDOPEPTIDASES; STAT2 TRANSCRIPTION FACTOR; VIRAL NONSTRUCTURAL PROTEINS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85046115626     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2018.04.003     Document Type: Article

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