Selective Cytotoxicity of Luteolin and Kaempferol on Cancerous Hepatocytes Obtained from Rat Model of Hepatocellular Carcinoma: Involvement of ROS-Mediated Mitochondrial Targeting

Nutrition and Cancer

Volumn 70, Issue 4, 2018, Pages 594-604

  Seydi, Enayatollah ^a,b   Salimi, Ahmad ^c   Rasekh, Hamid Reza ^d   Mohsenifar, Zhaleh ^d   Pourahmad, Jalal ^d  

^a ALBORZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ALBORZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ARDABIL UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOCHROME C; DIETHYLNITROSAMINE; KAEMPFEROL; LUTEOLIN; N (2 FLUORENYL)ACETAMIDE; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT; KAEMPFEROL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FLOW CYTOMETRY; LIVER CANCER CELL LINE; LIVER CELL; LIVER CELL CARCINOMA; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TARGETING SIGNAL; MITOCHONDRION; MITOCHONDRION SWELLING; MTT ASSAY; NONHUMAN; RAT; ANIMAL; APOPTOSIS; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL LIVER NEOPLASM; LIVER MITOCHONDRION; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

2-ACETYLAMINOFLUORENE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CYTOCHROMES C; DIETHYLNITROSAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; KAEMPFEROLS; LIVER NEOPLASMS, EXPERIMENTAL; LUTEOLIN; MALE; MITOCHONDRIA, LIVER; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 85046007166     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2018.1460679     Document Type: Article

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