Flavonoids identified from korean scutellaria baicalensis induce apoptosis by ROS generation and caspase activation on human fibrosarcoma cells

American Journal of Chinese Medicine

Volumn 42, Issue 2, 2014, Pages 465-483

  Zhang, Jue ^a   Park, Hyeon Soo ^b   Kim, Jin A ^b   Hong, Gyeong Eun ^b   Nagappan, Arulkumar ^b   Park, Kwang Il ^c   Kim, Gon Sup ^b  

^a BEIJING HOSPITAL   (China)

^b Gyeongsang National University   (South Korea)

^c UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Apoptosis; Flavonoids; Human Fibrosarcoma; Korean Scutellaria baicalensis G; Proteomic Analysis; Total ROS

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; BAICALIN; CASPASE 3; CASPASE 8; CASPASE 9; FLAVONOID; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; PROTEIN BAX; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; WOGONIN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG IDENTIFICATION; DRUG ISOLATION; ENZYME ACTIVATION; FIBROSARCOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PANCREAS CANCER; PROTEOMICS; SCUTELLARIA BAICALENSIS; STOMACH CANCER; TANDEM MASS SPECTROMETRY; UPREGULATION;

APOPTOSIS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASES; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROSARCOMA; FLAVONOIDS; GENE EXPRESSION; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN K; HUMANS; KOREA; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SCUTELLARIA BAICALENSIS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 84897870173     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X14500311     Document Type: Article

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