Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Science

Volumn 360, Issue 6386, 2018, Pages 331-335

  Filbin, Mariella G ^a,b,c,d,e   Tirosh, Itay ^c,d,f   Hovestadt, Volker ^a,c,d   Shaw, McKenzie L ^a,c,d   Escalante, Leah E ^a,c,d   Mathewson, Nathan D ^g   Neftel, Cyril ^a,c,d,h   Frank, Nelli ⁱ   Pelton, Kristine ^j   Hebert, Christine M ^a,c,d   Haberler, Christine ^k   Yizhak, Keren ^d   Gojo, Johannes ^e   Egervari, Kristof ^a   Mount, Christopher ^l   Van Galen, Peter ^a,c,d   Bonal, Dennis M ^b   Nguyen, Quang De ^b   Beck, Alexander ^a   Sinai, Claire ^b,j   Czech, Thomas ⁱ   Dorfer, Christian ⁱ   Goumnerova, Liliana ^b   Lavarino, Cinzia ^m   Carcaboso, Angel M ^m   Mora, Jaume ^m   Mylvaganam, Ravindra ^a   Luo, Christina C ^a   Peyrl, Andreas ^e   Popović, Mara ⁿ   Azizi, Amedeo ^e   Batchelor, Tracy T ^o   Frosch, Matthew P ^a   Martinez Lage, Maria ^a   Kieran, Mark W ^b   Bandopadhayay, Pratiti ^b,d   Beroukhim, Rameen ^d,p   Fritsch, Gerhard ⁱ   Getz, Gad ^a,d   Rozenblatt Rosen, Orit ^c,d   Wucherpfennig, Kai W ^g   Louis, David N ^a   Monje, Michelle ^l   Slavc, Irene ^e   Ligon, Keith L ^b,d,j   Golub, Todd R ^b,d   Regev, Aviv ^c,d,q   Bernstein, Bradley E ^a,c,d   Suvà, Mario L ^a,c,d   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e UNIV KLIN KINDER JUGENDHEILKUNDE   (Austria)

^f WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^g HARVARD MEDICAL SCHOOL   (United States)

^h LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

ⁱ MEDICAL UNIVERSITY OF VIENNA   (Austria)

^j BOSTON CHILDREN S HOSPITAL   (United States)

^k MEDICAL UNIVERSITY OF VIENNA   (Austria)

^l STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m HOSPITAL SANT JOAN DE DÉU   (Spain)

ⁿ UNIVERSITY OF LJUBLJANA   (Slovenia)

^o MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^p BRIGHAM AND WOMEN S HOSPITAL   (United States)

^q HOWARD HUGHES MEDICAL INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; ISOCITRATE DEHYDROGENASE; HISTONE; MAPK7 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 7; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

CELL; DEVELOPMENTAL BIOLOGY; DIFFERENTIATION; GENETICS; MUTATION; NERVOUS SYSTEM; PROTEIN; RNA; TUMOR;

ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE EXPRESSION; GENE MUTATION; GENETIC HETEROGENEITY; GLIOMA; HAPLOTYPE; HUMAN; HUMAN CELL; MOUSE; MUTANT; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; ONCOGENE; PRIORITY JOURNAL; RNA SEQUENCE; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; BRAIN TUMOR; CARCINOGENESIS; GENETICS; METABOLISM; MUTATION; OLIGODENDROGLIA; PATHOLOGY; PROCEDURES; SEQUENCE ANALYSIS;

BRAIN NEOPLASMS; CARCINOGENESIS; CELL PROLIFERATION; GLIOMA; HISTONES; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 7; MUTATION; OLIGODENDROGLIA; ONCOGENES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS;

EID: 85045656768     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aao4750     Document Type: Article

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