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Volumn 28, Issue 7, 2018, Pages 429-434

NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis

Author keywords

Antiplatelet; NADPH oxidase; NOX2; Oxidative stress; Platelet

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; ANTIOXIDANT; ANTITHROMBOCYTIC AGENT; CYBB PROTEIN, HUMAN; ENZYME INHIBITOR; REACTIVE OXYGEN METABOLITE;

EID: 85045475584     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2018.03.001     Document Type: Review
Times cited : (57)

References (69)
  • 2
    • 80051666038 scopus 로고    scopus 로고
    • Reactive oxygen species in cardiovascular disease
    • Sugamura, K., Keaney, J.F. Jr., Reactive oxygen species in cardiovascular disease. Free Radical Biol Med 51:September (5) (2011), 978–992.
    • (2011) Free Radical Biol Med , vol.51 , Issue.September (5) , pp. 978-992
    • Sugamura, K.1    Keaney, J.F.2
  • 3
    • 84929358935 scopus 로고    scopus 로고
    • Relationship between the increased haemostatic properties of blood platelets and oxidative stress level in multiple sclerosis patients with the secondary progressive stage
    • Morel, A., Bijak, M., Miller, E., Rywaniak, J., Miller, S., Saluk, J., Relationship between the increased haemostatic properties of blood platelets and oxidative stress level in multiple sclerosis patients with the secondary progressive stage. Oxid Med Cell Longevity, 2015, 2015, 240918.
    • (2015) Oxid Med Cell Longevity , vol.2015
    • Morel, A.1    Bijak, M.2    Miller, E.3    Rywaniak, J.4    Miller, S.5    Saluk, J.6
  • 4
    • 0031962580 scopus 로고    scopus 로고
    • Hydrogen peroxide is involved in collagen-induced platelet activation
    • Pignatelli, P., Pulcinelli, F.M., Lenti, L., Gazzaniga, P.P., Violi, F., Hydrogen peroxide is involved in collagen-induced platelet activation. Blood 91:January (2) (1998), 484–490.
    • (1998) Blood , vol.91 , Issue.January (2) , pp. 484-490
    • Pignatelli, P.1    Pulcinelli, F.M.2    Lenti, L.3    Gazzaniga, P.P.4    Violi, F.5
  • 5
    • 0001145160 scopus 로고    scopus 로고
    • Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation—role of arachidonic acid metabolism
    • Caccese, D., Pratico, D., Ghiselli, A., Natoli, S., Pignatelli, P., Sanguigni, V., et al. Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation—role of arachidonic acid metabolism. Thromb Haemostasis 83:March (3) (2000), 485–490.
    • (2000) Thromb Haemostasis , vol.83 , Issue.March (3) , pp. 485-490
    • Caccese, D.1    Pratico, D.2    Ghiselli, A.3    Natoli, S.4    Pignatelli, P.5    Sanguigni, V.6
  • 6
    • 0036285335 scopus 로고    scopus 로고
    • Generation of reactive oxygen species in blood platelets
    • Wachowicz, B., Olas, B., Zbikowska, H.M., Buczynski, A., Generation of reactive oxygen species in blood platelets. Platelets 13:May (3) (2002), 175–182.
    • (2002) Platelets , vol.13 , Issue.May (3) , pp. 175-182
    • Wachowicz, B.1    Olas, B.2    Zbikowska, H.M.3    Buczynski, A.4
  • 7
    • 84889884557 scopus 로고    scopus 로고
    • The role of intraplatelet reactive oxygen species in the regulation of platelet glycoprotein Ibalpha ectodomain shedding
    • Zhang, P., Du, J., Zhao, L., Wang, X., Zhang, Y., Yan, R., et al. The role of intraplatelet reactive oxygen species in the regulation of platelet glycoprotein Ibalpha ectodomain shedding. Thromb Res 132:6 (2013), 696–701.
    • (2013) Thromb Res , vol.132 , Issue.6 , pp. 696-701
    • Zhang, P.1    Du, J.2    Zhao, L.3    Wang, X.4    Zhang, Y.5    Yan, R.6
  • 8
    • 36549018143 scopus 로고    scopus 로고
    • Reactive oxygen species and human platelet GP IIb/IIIa receptor activation
    • Sill, J.C., Proper, J.A., Johnson, M.E., Uhl, C.B., Katusic, Z.S., Reactive oxygen species and human platelet GP IIb/IIIa receptor activation. Platelets 18:December (8) (2007), 613–619.
    • (2007) Platelets , vol.18 , Issue.December (8) , pp. 613-619
    • Sill, J.C.1    Proper, J.A.2    Johnson, M.E.3    Uhl, C.B.4    Katusic, Z.S.5
  • 9
    • 84907455071 scopus 로고    scopus 로고
    • Nox family NADPH oxidases: molecular mechanisms of activation
    • Brandes, R.P., Weissmann, N., Schroder, K., Nox family NADPH oxidases: molecular mechanisms of activation. Free Radical Biol Med 76:November (2014), 208–226.
    • (2014) Free Radical Biol Med , vol.76 , Issue.November , pp. 208-226
    • Brandes, R.P.1    Weissmann, N.2    Schroder, K.3
  • 10
    • 84893194030 scopus 로고    scopus 로고
    • The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation
    • Walsh, T.G., Berndt, M.C., Carrim, N., Cowman, J., Kenny, D., Metharom, P., The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation. Redox Biol 2 (2014), 178–186.
    • (2014) Redox Biol , vol.2 , pp. 178-186
    • Walsh, T.G.1    Berndt, M.C.2    Carrim, N.3    Cowman, J.4    Kenny, D.5    Metharom, P.6
  • 11
    • 84963706369 scopus 로고    scopus 로고
    • Platelet signaling: a complex interplay between inhibitory and activatory networks
    • Bye, A.P., Unsworth, A.J., Gibbins, J.M., Platelet signaling: a complex interplay between inhibitory and activatory networks. J Thromb Haemostasis 14:May (5) (2016), 918–930.
    • (2016) J Thromb Haemostasis , vol.14 , Issue.May (5) , pp. 918-930
    • Bye, A.P.1    Unsworth, A.J.2    Gibbins, J.M.3
  • 12
  • 13
    • 84905679657 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi
    • Jones, C.I., Tucker, K.L., Sasikumar, P., Sage, T., Kaiser, W.J., Moore, C., et al. Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi. J Thromb Haemostasis 12:August (8) (2014), 1342–1352.
    • (2014) J Thromb Haemostasis , vol.12 , Issue.August (8) , pp. 1342-1352
    • Jones, C.I.1    Tucker, K.L.2    Sasikumar, P.3    Sage, T.4    Kaiser, W.J.5    Moore, C.6
  • 14
    • 84929484690 scopus 로고    scopus 로고
    • Peroxiredoxin II is an antioxidant enzyme that negatively regulates collagen-stimulated platelet function
    • Jang, J.Y., Wang, S.B., Min, J.H., Chae, Y.H., Baek, J.Y., Yu, D.Y., et al. Peroxiredoxin II is an antioxidant enzyme that negatively regulates collagen-stimulated platelet function. J Biol Chem 290:May (18) (2015), 11432–11442.
    • (2015) J Biol Chem , vol.290 , Issue.May (18) , pp. 11432-11442
    • Jang, J.Y.1    Wang, S.B.2    Min, J.H.3    Chae, Y.H.4    Baek, J.Y.5    Yu, D.Y.6
  • 16
    • 84875465881 scopus 로고    scopus 로고
    • Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis
    • Dayal, S., Wilson, K.M., Motto, D.G., Miller, F.J. Jr., Chauhan, A.K., Lentz, S.R., Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis. Circulation 127:March (12) (2013), 1308–1316.
    • (2013) Circulation , vol.127 , Issue.March (12) , pp. 1308-1316
    • Dayal, S.1    Wilson, K.M.2    Motto, D.G.3    Miller, F.J.4    Chauhan, A.K.5    Lentz, S.R.6
  • 17
    • 84883418353 scopus 로고    scopus 로고
    • The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis
    • Wang, Z., Cai, F., Chen, X., Luo, M., Hu, L., Lu, Y., The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis. PLoS One, 8(9), 2013, e75044.
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e75044
    • Wang, Z.1    Cai, F.2    Chen, X.3    Luo, M.4    Hu, L.5    Lu, Y.6
  • 20
    • 47649095282 scopus 로고    scopus 로고
    • NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity
    • Gambaryan, S., Kobsar, A., Hartmann, S., Birschmann, I., Kuhlencordt, P.J., Muller-Esterl, W., et al. NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity. J Thromb Haemostasis 6:August (8) (2008), 1376–1384.
    • (2008) J Thromb Haemostasis , vol.6 , Issue.August (8) , pp. 1376-1384
    • Gambaryan, S.1    Kobsar, A.2    Hartmann, S.3    Birschmann, I.4    Kuhlencordt, P.J.5    Muller-Esterl, W.6
  • 21
    • 17944369584 scopus 로고    scopus 로고
    • Involvement of NADH/NADPH oxidase in human platelet ROS production
    • Seno, T., Inoue, N., Gao, D., Okuda, M., Sumi, Y., Matsui, K., et al. Involvement of NADH/NADPH oxidase in human platelet ROS production. Thromb Res 103:September (5) (2001), 399–409.
    • (2001) Thromb Res , vol.103 , Issue.September (5) , pp. 399-409
    • Seno, T.1    Inoue, N.2    Gao, D.3    Okuda, M.4    Sumi, Y.5    Matsui, K.6
  • 22
    • 84961233719 scopus 로고    scopus 로고
    • Differential roles of the NADPH-Oxidase 1 and 2 in platelet activation and thrombosis
    • Delaney, M.K., Kim, K., Estevez, B., Xu, Z., Stojanovic-Terpo, A., Shen, B., et al. Differential roles of the NADPH-Oxidase 1 and 2 in platelet activation and thrombosis. Arterioscler Thromb Vasc Biol 36:May (5) (2016 May), 846–854.
    • (2016) Arterioscler Thromb Vasc Biol , vol.36 , Issue.May (5) , pp. 846-854
    • Delaney, M.K.1    Kim, K.2    Estevez, B.3    Xu, Z.4    Stojanovic-Terpo, A.5    Shen, B.6
  • 23
    • 0025953364 scopus 로고
    • Superoxide dismutase triggers activation of “primed” platelets
    • Iuliano, L., Pratico, D., Ghiselli, A., Bonavita, M.S., Violi, F., Superoxide dismutase triggers activation of “primed” platelets. Arch Biochem Biophys 289:August (1) (1991), 180–183.
    • (1991) Arch Biochem Biophys , vol.289 , Issue.August (1) , pp. 180-183
    • Iuliano, L.1    Pratico, D.2    Ghiselli, A.3    Bonavita, M.S.4    Violi, F.5
  • 24
    • 0036682478 scopus 로고    scopus 로고
    • NAD(P)H oxidase-dependent platelet superoxide anion release increases platelet recruitment
    • Krotz, F., Sohn, H.Y., Gloe, T., Zahler, S., Riexinger, T., Schiele, T.M., et al. NAD(P)H oxidase-dependent platelet superoxide anion release increases platelet recruitment. Blood 100:August (3) (2002), 917–924.
    • (2002) Blood , vol.100 , Issue.August (3) , pp. 917-924
    • Krotz, F.1    Sohn, H.Y.2    Gloe, T.3    Zahler, S.4    Riexinger, T.5    Schiele, T.M.6
  • 25
    • 27144548487 scopus 로고    scopus 로고
    • Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway
    • Begonja, A.J., Gambaryan, S., Geiger, J., Aktas, B., Pozgajova, M., Nieswandt, B., et al. Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway. Blood 106:October (8) (2005), 2757–2760.
    • (2005) Blood , vol.106 , Issue.October (8) , pp. 2757-2760
    • Begonja, A.J.1    Gambaryan, S.2    Geiger, J.3    Aktas, B.4    Pozgajova, M.5    Nieswandt, B.6
  • 26
    • 33645297161 scopus 로고    scopus 로고
    • Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS
    • Begonja, A.J., Teichmann, L., Geiger, J., Gambaryan, S., Walter, U., Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS. Blood Cells Mol Dis 36:March–April (2) (2006), 166–170.
    • (2006) Blood Cells Mol Dis , vol.36 , Issue.March–April (2) , pp. 166-170
    • Begonja, A.J.1    Teichmann, L.2    Geiger, J.3    Gambaryan, S.4    Walter, U.5
  • 27
    • 84874525887 scopus 로고    scopus 로고
    • Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition
    • Liu, Y., Davidson, B.P., Yue, Q., Belcik, T., Xie, A., Inaba, Y., et al. Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition. Circ Cardiovasc Imaging 6:January (1) (2013), 74–82.
    • (2013) Circ Cardiovasc Imaging , vol.6 , Issue.January (1) , pp. 74-82
    • Liu, Y.1    Davidson, B.P.2    Yue, Q.3    Belcik, T.4    Xie, A.5    Inaba, Y.6
  • 28
    • 80054704273 scopus 로고    scopus 로고
    • NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies
    • Sirker, A., Zhang, M., Shah, A.M., NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. Basic Res Cardiol 106:September (5) (2011), 735–747.
    • (2011) Basic Res Cardiol , vol.106 , Issue.September (5) , pp. 735-747
    • Sirker, A.1    Zhang, M.2    Shah, A.M.3
  • 29
    • 84862869038 scopus 로고    scopus 로고
    • Different behaviour of NOX2 activation in patients with paroxysmal/persistent or permanent atrial fibrillation
    • Cangemi, R., Celestini, A., Calvieri, C., Carnevale, R., Pastori, D., Nocella, C., et al. Different behaviour of NOX2 activation in patients with paroxysmal/persistent or permanent atrial fibrillation. Heart 98:July (14) (2012), 1063–1066.
    • (2012) Heart , vol.98 , Issue.July (14) , pp. 1063-1066
    • Cangemi, R.1    Celestini, A.2    Calvieri, C.3    Carnevale, R.4    Pastori, D.5    Nocella, C.6
  • 30
    • 84942163075 scopus 로고    scopus 로고
    • Nox2 up-regulation is associated with an enhanced risk of atrial fibrillation in patients with pneumonia
    • Violi, F., Carnevale, R., Calvieri, C., Nocella, C., Falcone, M., Farcomeni, A., et al. Nox2 up-regulation is associated with an enhanced risk of atrial fibrillation in patients with pneumonia. Thorax 70:October (10) (2015), 961–966.
    • (2015) Thorax , vol.70 , Issue.October (10) , pp. 961-966
    • Violi, F.1    Carnevale, R.2    Calvieri, C.3    Nocella, C.4    Falcone, M.5    Farcomeni, A.6
  • 31
    • 84939424111 scopus 로고    scopus 로고
    • Pathophysiology and treatments of oxidative injury in ischemic stroke: focus on the phagocytic NADPH oxidase 2
    • Carbone, F., Teixeira, P.C., Braunersreuther, V., Mach, F., Vuilleumier, N., Montecucco, F., Pathophysiology and treatments of oxidative injury in ischemic stroke: focus on the phagocytic NADPH oxidase 2. Antioxid Redox Signal 23:August (5) (2015), 460–489.
    • (2015) Antioxid Redox Signal , vol.23 , Issue.August (5) , pp. 460-489
    • Carbone, F.1    Teixeira, P.C.2    Braunersreuther, V.3    Mach, F.4    Vuilleumier, N.5    Montecucco, F.6
  • 32
    • 84876132783 scopus 로고    scopus 로고
    • NOX2 up-regulation is associated with artery dysfunction in patients with peripheral artery disease
    • Loffredo, L., Carnevale, R., Cangemi, R., Angelico, F., Augelletti, T., Di Santo, S., et al. NOX2 up-regulation is associated with artery dysfunction in patients with peripheral artery disease. Int J Cardiol 165:April (1) (2013), 184–192.
    • (2013) Int J Cardiol , vol.165 , Issue.April (1) , pp. 184-192
    • Loffredo, L.1    Carnevale, R.2    Cangemi, R.3    Angelico, F.4    Augelletti, T.5    Di Santo, S.6
  • 33
    • 84944271850 scopus 로고    scopus 로고
    • NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation
    • Kim, K., Li, J., Tseng, A., Andrews, R.K., Cho, J., NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation. Blood 126:October (16) (2015), 1952–1964.
    • (2015) Blood , vol.126 , Issue.October (16) , pp. 1952-1964
    • Kim, K.1    Li, J.2    Tseng, A.3    Andrews, R.K.4    Cho, J.5
  • 36
    • 4444294006 scopus 로고    scopus 로고
    • gp91phox-dependent expression of platelet CD40 ligand
    • Pignatelli, P., Sanguigni, V., Lenti, L., Ferro, D., Finocchi, A., Rossi, P., et al. gp91phox-dependent expression of platelet CD40 ligand. Circulation 110:September (10) (2004), 1326–1329.
    • (2004) Circulation , vol.110 , Issue.September (10) , pp. 1326-1329
    • Pignatelli, P.1    Sanguigni, V.2    Lenti, L.3    Ferro, D.4    Finocchi, A.5    Rossi, P.6
  • 37
    • 84899747619 scopus 로고    scopus 로고
    • Platelet NOX, a novel target for anti-thrombotic treatment
    • Violi, F., Pignatelli, P., Platelet NOX, a novel target for anti-thrombotic treatment. Thromb Haemostasis 111:May (5) (2014), 817–823.
    • (2014) Thromb Haemostasis , vol.111 , Issue.May (5) , pp. 817-823
    • Violi, F.1    Pignatelli, P.2
  • 38
    • 51649094903 scopus 로고    scopus 로고
    • Oxidative stress is associated with arterial dysfunction and enhanced intima-media thickness in children with hypercholesterolemia: the potential role of nicotinamide-adenine dinucleotide phosphate oxidase
    • Martino, F., Loffredo, L., Carnevale, R., Sanguigni, V., Martino, E., Catasca, E., et al. Oxidative stress is associated with arterial dysfunction and enhanced intima-media thickness in children with hypercholesterolemia: the potential role of nicotinamide-adenine dinucleotide phosphate oxidase. Pediatrics 122:September (3) (2008), e648–e655.
    • (2008) Pediatrics , vol.122 , Issue.September (3) , pp. e648-e655
    • Martino, F.1    Loffredo, L.2    Carnevale, R.3    Sanguigni, V.4    Martino, E.5    Catasca, E.6
  • 39
    • 79551476712 scopus 로고    scopus 로고
    • Inherited human gp91phox deficiency is associated with impaired isoprostane formation and platelet dysfunction
    • Pignatelli, P., Carnevale, R., Di Santo, S., Bartimoccia, S., Sanguigni, V., Lenti, L., et al. Inherited human gp91phox deficiency is associated with impaired isoprostane formation and platelet dysfunction. Arterioscler Thromb Vasc Biol 31:February (2) (2011), 423–434.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.February (2) , pp. 423-434
    • Pignatelli, P.1    Carnevale, R.2    Di Santo, S.3    Bartimoccia, S.4    Sanguigni, V.5    Lenti, L.6
  • 40
    • 84991721119 scopus 로고    scopus 로고
    • RhoA and Rac1 GTPases fifferentially regulate agonist-receptor mediated reactive oxygen species generation in platelets
    • Akbar, H., Duan, X., Saleem, S., Davis, A.K., Zheng, Y., RhoA and Rac1 GTPases fifferentially regulate agonist-receptor mediated reactive oxygen species generation in platelets. PLoS One, 11(9), 2016, e0163227.
    • (2016) PLoS One , vol.11 , Issue.9
    • Akbar, H.1    Duan, X.2    Saleem, S.3    Davis, A.K.4    Zheng, Y.5
  • 41
    • 84928757883 scopus 로고    scopus 로고
    • Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets
    • Dutting, S., Heidenreich, J., Cherpokova, D., Amin, E., Zhang, S.C., Ahmadian, M.R., et al. Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets. J Thromb Haemostasis 13:May (5) (2015), 827–838.
    • (2015) J Thromb Haemostasis , vol.13 , Issue.May (5) , pp. 827-838
    • Dutting, S.1    Heidenreich, J.2    Cherpokova, D.3    Amin, E.4    Zhang, S.C.5    Ahmadian, M.R.6
  • 42
    • 78549272749 scopus 로고    scopus 로고
    • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
    • Lievens, D., Zernecke, A., Seijkens, T., Soehnlein, O., Beckers, L., Munnix, I.C., et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood 116:November (20) (2010), 4317–4327.
    • (2010) Blood , vol.116 , Issue.November (20) , pp. 4317-4327
    • Lievens, D.1    Zernecke, A.2    Seijkens, T.3    Soehnlein, O.4    Beckers, L.5    Munnix, I.C.6
  • 43
    • 0037143597 scopus 로고    scopus 로고
    • Platelet-derived CD40L: the switch-hitting player of cardiovascular disease
    • Andre, P., Nannizzi-Alaimo, L., Prasad, S.K., Phillips, D.R., Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation 106:August (8) (2002), 896–899.
    • (2002) Circulation , vol.106 , Issue.August (8) , pp. 896-899
    • Andre, P.1    Nannizzi-Alaimo, L.2    Prasad, S.K.3    Phillips, D.R.4
  • 45
    • 84912122085 scopus 로고    scopus 로고
    • Different degrees of NADPH oxidase 2 regulation and in vivo platelet activation: lesson from chronic granulomatous disease
    • Carnevale, R., Loffredo, L., Sanguigni, V., Plebani, A., Rossi, P., Pignata, C., et al. Different degrees of NADPH oxidase 2 regulation and in vivo platelet activation: lesson from chronic granulomatous disease. J Am Heart Assoc, 3(June (3)), 2014, e000920.
    • (2014) J Am Heart Assoc , vol.3 , Issue.June (3)
    • Carnevale, R.1    Loffredo, L.2    Sanguigni, V.3    Plebani, A.4    Rossi, P.5    Pignata, C.6
  • 46
    • 0038494921 scopus 로고    scopus 로고
    • Platelet-collagen interaction: is GPVI the central receptor?
    • Nieswandt, B., Watson, S.P., Platelet-collagen interaction: is GPVI the central receptor?. Blood 102:July (2) (2003), 449–461.
    • (2003) Blood , vol.102 , Issue.July (2) , pp. 449-461
    • Nieswandt, B.1    Watson, S.P.2
  • 47
    • 84861677598 scopus 로고    scopus 로고
    • ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways
    • Arthur, J.F., Qiao, J., Shen, Y., Davis, A.K., Dunne, E., Berndt, M.C., et al. ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways. J Thromb Haemostasis 10:June (6) (2012), 1133–1141.
    • (2012) J Thromb Haemostasis , vol.10 , Issue.June (6) , pp. 1133-1141
    • Arthur, J.F.1    Qiao, J.2    Shen, Y.3    Davis, A.K.4    Dunne, E.5    Berndt, M.C.6
  • 48
    • 80054686061 scopus 로고    scopus 로고
    • LDL from obese patients with the metabolic syndrome show increased lipid peroxidation and activate platelets
    • Colas, R., Sassolas, A., Guichardant, M., Cugnet-Anceau, C., Moret, M., Moulin, P., et al. LDL from obese patients with the metabolic syndrome show increased lipid peroxidation and activate platelets. Diabetologia 54:November (11) (2011), 2931–2940.
    • (2011) Diabetologia , vol.54 , Issue.November (11) , pp. 2931-2940
    • Colas, R.1    Sassolas, A.2    Guichardant, M.3    Cugnet-Anceau, C.4    Moret, M.5    Moulin, P.6
  • 49
    • 0037164094 scopus 로고    scopus 로고
    • Platelet activation in obese women: role of inflammation and oxidant stress
    • Davi, G., Guagnano, M.T., Ciabattoni, G., Basili, S., Falco, A., Marinopiccoli, M., et al. Platelet activation in obese women: role of inflammation and oxidant stress. JAMA 288:October (16) (2002 2), 2008–2014.
    • (2002) JAMA , vol.288 , Issue.October (16) , pp. 2008-2014
    • Davi, G.1    Guagnano, M.T.2    Ciabattoni, G.3    Basili, S.4    Falco, A.5    Marinopiccoli, M.6
  • 50
    • 84884393288 scopus 로고    scopus 로고
    • Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype
    • Vazzana, N., Ganci, A., Cefalu, A.B., Lattanzio, S., Noto, D., Santoro, N., et al. Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. J Am Heart Assoc, 2(April (2)), 2013, e000063.
    • (2013) J Am Heart Assoc , vol.2 , Issue.April (2)
    • Vazzana, N.1    Ganci, A.2    Cefalu, A.B.3    Lattanzio, S.4    Noto, D.5    Santoro, N.6
  • 51
    • 84928320169 scopus 로고    scopus 로고
    • Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade
    • Magwenzi, S., Woodward, C., Wraith, K.S., Aburima, A., Raslan, Z., Jones, H., et al. Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade. Blood 125:April (17) (2015), 2693–2703.
    • (2015) Blood , vol.125 , Issue.April (17) , pp. 2693-2703
    • Magwenzi, S.1    Woodward, C.2    Wraith, K.S.3    Aburima, A.4    Raslan, Z.5    Jones, H.6
  • 52
    • 85047289202 scopus 로고    scopus 로고
    • Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways
    • Wraith, K.S., Magwenzi, S., Aburima, A., Wen, Y., Leake, D., Naseem, K.M., Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways. Blood 122:July (4) (2013), 580–589.
    • (2013) Blood , vol.122 , Issue.July (4) , pp. 580-589
    • Wraith, K.S.1    Magwenzi, S.2    Aburima, A.3    Wen, Y.4    Leake, D.5    Naseem, K.M.6
  • 53
    • 36048938222 scopus 로고    scopus 로고
    • Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A
    • Korporaal, S.J., Van Eck M, A.J., Ijsseldijk, M., Out, R., Lisman, T., et al. Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A. Arterioscler Thromb Vasc Biol 27:November (11) (2007), 2476–2483.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.November (11) , pp. 2476-2483
    • Korporaal, S.J.1    Van Eck M, A.J.2    Ijsseldijk, M.3    Out, R.4    Lisman, T.5
  • 54
    • 34948882706 scopus 로고    scopus 로고
    • Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype
    • Podrez, E.A., Byzova, T.V., Febbraio, M., Salomon, R.G., Ma, Y., Valiyaveettil, M., et al. Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype. Nat Med 13:September (9) (2007), 1086–1095.
    • (2007) Nat Med , vol.13 , Issue.September (9) , pp. 1086-1095
    • Podrez, E.A.1    Byzova, T.V.2    Febbraio, M.3    Salomon, R.G.4    Ma, Y.5    Valiyaveettil, M.6
  • 55
    • 84907776794 scopus 로고    scopus 로고
    • LDL oxidation by platelets propagates platelet activation via an oxidative stress-mediated mechanism
    • Carnevale, R., Bartimoccia, S., Nocella, C., Di Santo, S., Loffredo, L., Illuminati, G., et al. LDL oxidation by platelets propagates platelet activation via an oxidative stress-mediated mechanism. Atherosclerosis 237:November (1) (2014), 108–116.
    • (2014) Atherosclerosis , vol.237 , Issue.November (1) , pp. 108-116
    • Carnevale, R.1    Bartimoccia, S.2    Nocella, C.3    Di Santo, S.4    Loffredo, L.5    Illuminati, G.6
  • 56
    • 80051551971 scopus 로고    scopus 로고
    • Anoxia-reoxygenation enhances platelet thromboxane A2 production via reactive oxygen species-generated NOX2: effect in patients undergoing elective percutaneous coronary intervention
    • Basili, S., Pignatelli, P., Tanzilli, G., Mangieri, E., Carnevale, R., Nocella, C., et al. Anoxia-reoxygenation enhances platelet thromboxane A2 production via reactive oxygen species-generated NOX2: effect in patients undergoing elective percutaneous coronary intervention. Arterioscler Thromb Vasc Biol 31:August (8) (2011), 1766–1771.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.August (8) , pp. 1766-1771
    • Basili, S.1    Pignatelli, P.2    Tanzilli, G.3    Mangieri, E.4    Carnevale, R.5    Nocella, C.6
  • 57
    • 0038755593 scopus 로고    scopus 로고
    • Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration
    • Davi, G., Chiarelli, F., Santilli, F., Pomilio, M., Vigneri, S., Falco, A., et al. Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. Circulation 107:July (25) (2003), 3199–3203.
    • (2003) Circulation , vol.107 , Issue.July (25) , pp. 3199-3203
    • Davi, G.1    Chiarelli, F.2    Santilli, F.3    Pomilio, M.4    Vigneri, S.5    Falco, A.6
  • 58
    • 84891465151 scopus 로고    scopus 로고
    • Relationship between platelet and urinary 8-Iso-PGF2alpha levels in subjects with different degrees of NOX2 regulation
    • Carnevale, R., Iuliano, L., Nocella, C., Bartimoccia, S., Trape, S., Russo, R., et al. Relationship between platelet and urinary 8-Iso-PGF2alpha levels in subjects with different degrees of NOX2 regulation. J Am Heart Assoc, 2(June (3)), 2013, e000198.
    • (2013) J Am Heart Assoc , vol.2 , Issue.June (3)
    • Carnevale, R.1    Iuliano, L.2    Nocella, C.3    Bartimoccia, S.4    Trape, S.5    Russo, R.6
  • 59
    • 85004125679 scopus 로고    scopus 로고
    • NADPH oxidase-2 and atherothrombosis: insight from chronic granulomatous disease
    • Violi, F., Carnevale, R., Loffredo, L., Pignatelli, P., Gallin, J.I., NADPH oxidase-2 and atherothrombosis: insight from chronic granulomatous disease. Arterioscler Thromb Vasc Biol 37:February (2) (2017), 218–225.
    • (2017) Arterioscler Thromb Vasc Biol , vol.37 , Issue.February (2) , pp. 218-225
    • Violi, F.1    Carnevale, R.2    Loffredo, L.3    Pignatelli, P.4    Gallin, J.I.5
  • 60
    • 0343527886 scopus 로고    scopus 로고
    • C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population
    • Ito, D., Murata, M., Watanabe, K., Yoshida, T., Saito, I., Tanahashi, N., et al. C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population. Stroke 31:April (4) (2000), 936–939.
    • (2000) Stroke , vol.31 , Issue.April (4) , pp. 936-939
    • Ito, D.1    Murata, M.2    Watanabe, K.3    Yoshida, T.4    Saito, I.5    Tanahashi, N.6
  • 61
    • 14344251109 scopus 로고    scopus 로고
    • The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediates
    • Vitseva, O., Flockhart, D.A., Jin, Y., Varghese, S., Freedman, J.E., The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediates. J Pharmacol Exp Ther 312:March (3) (2005), 1144–1150.
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.March (3) , pp. 1144-1150
    • Vitseva, O.1    Flockhart, D.A.2    Jin, Y.3    Varghese, S.4    Freedman, J.E.5
  • 62
    • 35048860281 scopus 로고    scopus 로고
    • Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance
    • Stef, G., Csiszar, A., Ziangmin, Z., Ferdinandy, P., Ungvari, Z., Veress, G., Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance. Pharmacol Rep 59:July–August (4) (2007), 428–436.
    • (2007) Pharmacol Rep , vol.59 , Issue.July–August (4) , pp. 428-436
    • Stef, G.1    Csiszar, A.2    Ziangmin, Z.3    Ferdinandy, P.4    Ungvari, Z.5    Veress, G.6
  • 63
    • 84861062943 scopus 로고    scopus 로고
    • Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
    • Lassegue, B., San Martin, A., Griendling, K.K., Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 110:May (10) (2012), 1364–1390.
    • (2012) Circ Res , vol.110 , Issue.May (10) , pp. 1364-1390
    • Lassegue, B.1    San Martin, A.2    Griendling, K.K.3
  • 64
    • 84863115260 scopus 로고    scopus 로고
    • Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation
    • Bosco, E.E., Kumar, S., Marchioni, F., Biesiada, J., Kordos, M., Szczur, K., et al. Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. Chem Biol 19:February (2) (2012), 228–242.
    • (2012) Chem Biol , vol.19 , Issue.February (2) , pp. 228-242
    • Bosco, E.E.1    Kumar, S.2    Marchioni, F.3    Biesiada, J.4    Kordos, M.5    Szczur, K.6
  • 65
    • 80052235340 scopus 로고    scopus 로고
    • NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action
    • Jaquet, V., Marcoux, J., Forest, E., Leidal, K.G., McCormick, S., Westermaier, Y., et al. NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action. Br J Pharmacol 164:September (2b) (2011), 507–520.
    • (2011) Br J Pharmacol , vol.164 , Issue.September (2b) , pp. 507-520
    • Jaquet, V.1    Marcoux, J.2    Forest, E.3    Leidal, K.G.4    McCormick, S.5    Westermaier, Y.6
  • 66
    • 84862743816 scopus 로고    scopus 로고
    • Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits
    • Smith, S.M., Min, J., Ganesh, T., Diebold, B., Kawahara, T., Zhu, Y., et al. Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chem Biol 19:June (6) (2012), 752–763.
    • (2012) Chem Biol , vol.19 , Issue.June (6) , pp. 752-763
    • Smith, S.M.1    Min, J.2    Ganesh, T.3    Diebold, B.4    Kawahara, T.5    Zhu, Y.6
  • 67
    • 84939452794 scopus 로고    scopus 로고
    • Evolution of NADPH oxidase inhibitors: selectivity and mechanisms for target engagement
    • Altenhofer, S., Radermacher, K.A., Kleikers, P.W., Wingler, K., Schmidt, H.H., Evolution of NADPH oxidase inhibitors: selectivity and mechanisms for target engagement. Antioxid Redox Signal 23:August (5) (2015), 406–427.
    • (2015) Antioxid Redox Signal , vol.23 , Issue.August (5) , pp. 406-427
    • Altenhofer, S.1    Radermacher, K.A.2    Kleikers, P.W.3    Wingler, K.4    Schmidt, H.H.5
  • 68
    • 78649686720 scopus 로고    scopus 로고
    • Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque
    • Dwivedi, S., Pandey, D., Khandoga, A.L., Brandl, R., Siess, W., Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque. J Transl Med, 8(December), 2010, 128.
    • (2010) J Transl Med , vol.8 , Issue.December , pp. 128
    • Dwivedi, S.1    Pandey, D.2    Khandoga, A.L.3    Brandl, R.4    Siess, W.5
  • 69
    • 34447648178 scopus 로고    scopus 로고
    • Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation
    • Akbar, H., Kim, J., Funk, K., Cancelas, J.A., Shang, X., Chen, L., et al. Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation. J Thromb Haemostasis 5:August (8) (2007), 1747–1755.
    • (2007) J Thromb Haemostasis , vol.5 , Issue.August (8) , pp. 1747-1755
    • Akbar, H.1    Kim, J.2    Funk, K.3    Cancelas, J.A.4    Shang, X.5    Chen, L.6


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