gp91phox-dependent expression of platelet CD40 ligand

Circulation

Volumn 110, Issue 10, 2004, Pages 1326-1329

  Pignatelli, P ^a   Sanguigni, V ^b   Lenti, L ^a   Ferro, D ^a   Finocchi, A ^b   Rossi, P ^b   Violi, Francesco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

CD40 ligand; NADPH oxidase; Oxidative stress; Platelets

Indexed keywords

ANTIOXIDANT; ARACHIDONIC ACID; CATALASE; CD40 LIGAND; COLLAGEN; GLYCOPROTEIN GP 91; MANNITOL; PHOSPHOLIPASE A2 INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE DISMUTASE; THROMBIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THROMBOCYTE;

ADULT; ANTIOXIDANTS; ARACHIDONIC ACID; ARACHIDONIC ACIDS; ASPIRIN; BLOOD PLATELETS; CATALASE; CD40 LIGAND; COLLAGEN; GRANULOMATOUS DISEASE, CHRONIC; HUMANS; MALE; MANNITOL; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; PHOSPHOLIPASES A; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES; THROMBIN;

EID: 4444294006     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000134963.77201.55     Document Type: Article

References (14)

1. Schoenbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci. 2001;58:4-43.
2. André P, Nannizzi-Alaimo L, Prasad SK, et al. Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation. 2002;106:896-899.
3. Pignatelli P, Lenti L, Sanguigni V, et al. Carnitine inhibits arachidonic acid accumulation into platelet phospholipids: effects on platelet function and oxidative stress. Am J Physiol Heart Circ Physiol. 2003;284:H41-H48.
4. Burritt JB, DeLeo FR, McDonald CL, et al. Phage display epitome mapping of human neutrophil flavocytocrome b558: identification of two juxtaposed extracellular domains. J Biol Chem. 2001;276:2053-2061.
5. Mackay IR, Rosen FS. Immunodeficiency disease caused by defects in phagocytes. N Engl J Med. 2000;343:1703-1714.
6. Rae J, Newburger PE, Dinauer MC, et al. X-linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91 phox component of respiratory burst oxidase. Am J Hum Genet. 1998;62:1320-1331.
7. Krotz F, Sohn H Y, Gloe T, et al. NAD(P)H oxidase-dependent platelet Superoxide anion release increases platelet recruitment. Blood. 2002;100:917-924.
8. Schiffrin EL, Touyz RM. Inflammation and vascular hypertrophy induced by angiotensin ii: role of NADPH oxidase-derived reactive oxygen species independently of blood pressure elevation? Arterioscler Thromb Vasc Biol. 2003;23:707-709.
9. Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res. 2000;86:494-501.
10. Vignais PV. The superoxide-generating NADPH oxidase: structural aspects and activation mechanism. Cell Mol Life Sci. 2002;59:1428-1459.
11. Shiose A, Sumimoto H. Arachidonic acid and phosphorylation synergistically induce a conformational change pf p47phox to activate the phagocyte NADPH oxidase. J Biol Chem. 2000;275:13793-13801.
12. Stumpf C, Lehner C, Eskafi S, et al. Enhanced levels of CD154 (CD40 ligand) on platelets in patients with chronic heart failure. Eur J Heart Fail. 2003;5:629-637.
13. Mach F, Schonbeck U, Sukhova GK, et al. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature. 1998;394:200-203.
14. Schonbeck U, Gerdes N, Varo N, et al. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. Circulation. 2002;106:2888-2893.