Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis

Circulation

Volumn 127, Issue 12, 2013, Pages 1308-1316

  Dayal, Sanjana ^a   Wilson, Katina M ^a   Motto, David G ^a   Miller Jr , Francis J ^a   Chauhan, Anil K ^a   Lentz, Steven R ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Aging; Blood platelets; Thrombosis

Indexed keywords

APOCYNIN; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; FIBRINOGEN; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ALPHA2B BETA 3; GLUTATHIONE PEROXIDASE 1; HYDROGEN PEROXIDE; MACROGOL; PROTEIN P47; THROMBIN; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CAROTID ARTERY; CAROTID ARTERY INJURY; CAROTID ARTERY OBSTRUCTION; CAROTID ARTERY THROMBOSIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENE OVEREXPRESSION; INFERIOR CAVA VEIN; INFERIOR VENA CAVA THROMBOSIS; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHOTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; TRANSGENIC MOUSE; VEIN THROMBOSIS; WILD TYPE;

ACETOPHENONES; AGING; ANIMALS; BLOOD PLATELETS; CATALASE; FEMALE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, ANIMAL; NADPH OXIDASE; OXIDATIVE STRESS; PLATELET ACTIVATION; POLYETHYLENE GLYCOLS; RISK FACTORS; SUPEROXIDE DISMUTASE; THROMBOSIS;

EID: 84875465881     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.000966     Document Type: Article

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