Evidence of insulin-dependent signalling mechanisms produced by Citrus sinensis (L.) Osbeck fruit peel in an insulin resistant diabetic animal model

Food and Chemical Toxicology

Volumn 116, Issue , 2018, Pages 86-99

  Sathiyabama, Rajiv Gandhi ^a   Rajiv Gandhi, Gopalsamy ^a   Denadai, Marina ^a   Sridharan, Gurunagarajan ^b   Jothi, Gnanasekaran ^b   Sasikumar, Ponnusamy ^c   Siqueira Quintans, Jullyana de Souza ^a   Narain, Narendra ^a   Cuevas, Luis Eduardo ^d   Coutinho, Henrique Douglas Melo ^e   Ramos, Andreza Guedes Barbosa ^a   Quintans Júnior, Lucindo José ^a   Gurgel, Ricardo Queiroz ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^b SRIMAD ANDAVAN ARTS AND SCIENCE COLLEGE   (India)

^c UNIVERSITY AT BUFFALO   (United States)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^e REGIONAL UNIVERSITY OF CARIRI   (Brazil)

Author keywords

Adipose; Citrus sinensis; Diabetes; Histology; Insulin receptor; Pancreatic cell

Indexed keywords

ANTIDIABETIC AGENT; CITRUS SINENSIS EXTRACT; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR; METHANOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOL DERIVATIVE; PLANT EXTRACT; UNCLASSIFIED DRUG; CREATININE; INSULIN; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BODY WEIGHT; CELL PROTECTION; CONTROLLED STUDY; DIET RESTRICTION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; FEMALE; FLUID INTAKE; FOOD INTAKE; FRUIT; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; IMMUNOREACTIVITY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SIGNALING; LIPID DIET; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SWEET ORANGE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ADIPOSE TISSUE; ANIMAL; BLOOD; CHEMISTRY; CITRUS; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE TOLERANCE TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER FUNCTION TEST; METABOLISM; OBESITY; PANCREAS ISLET; PATHOPHYSIOLOGY; PLANT STRUCTURES; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; WISTAR RAT;

ADIPOSE TISSUE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITRUS; CREATININE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; LIVER FUNCTION TESTS; MALE; OBESITY; PHENOLS; PLANT EXTRACTS; PLANT STRUCTURES; RATS, WISTAR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; STREPTOZOCIN; TANDEM MASS SPECTROMETRY;

EID: 85045411390     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2018.03.050     Document Type: Article

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