Whether to push or pull? Nicotine reduction and non-combusted alternatives - Two strategies for reducing smoking and improving public health

Preventive Medicine

Volumn 117, Issue , 2018, Pages 8-14

  Smith, Tracy T ^a   Hatsukami, Dorothy K ^b   Benowitz, Neal L ^c   Colby, Suzanne M ^d   McClernon, F Joseph ^e   Strasser, Andrew A ^f   Tidey, Jennifer W ^d   White, Cassidy M ^g   Donny, Eric C ^g  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BROWN UNIVERSITY   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative nicotine delivery systems; E cigarettes; Endgame; Nicotine reduction

Indexed keywords

NICOTINE;

ARTICLE; ASSOCIATION; CRAVING; FOOD AND DRUG ADMINISTRATION; HABITUATION; HEALTH BELIEF; HEALTH CARE POLICY; HEALTH HAZARD; HUMAN; PRIORITY JOURNAL; PROGNOSIS; PUBLIC HEALTH; REINFORCEMENT; REWARD; RISK REDUCTION; SMOKING CESSATION; TOBACCO; TOBACCO DEPENDENCE; TOBACCO USE; ADDICTION; ELECTRONIC CIGARETTE; PROCEDURES; PSYCHOLOGY; SMOKING; SMOKING REDUCTION;

BEHAVIOR, ADDICTIVE; ELECTRONIC NICOTINE DELIVERY SYSTEMS; HUMANS; NICOTINE; PUBLIC HEALTH; SMOKING REDUCTION; TOBACCO SMOKING;

EID: 85044867374     PISSN: 00917435     EISSN: 10960260     Source Type: Journal    
DOI: 10.1016/j.ypmed.2018.03.021     Document Type: Article

References (123)

1. Abrams, D.B., Promise and peril of e-cigarettes: can disruptive technology make cigarettes obsolete?. JAMA 311:2 (2014), 135–136.
2. Action on Smoking and Health, ASH Factsheet: Use of E-cigarettes (vapourisers) Among Adults in Great Britain. 2017.
3. Adkison, S.E., et al. Electronic nicotine delivery systems: international tobacco control four-country survey. Am. J. Prev. Med. 44:3 (2013), 207–215.
4. Babb, S., et al. Quitting smoking among adults - United States, 2000–2015. MMWR Morb. Mortal. Wkly Rep. 65:52 (2017), 1457–1464.
5. Baicker, K., Chandra, A., Evidence-based health policy. N. Engl. J. Med. 377:25 (2017), 2413–2415.
6. Balleine, B.W., O'Doherty, J.P., Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action. Neuropsychopharmacology 35:1 (2010), 48–69.
7. Bates, C., The Tobacco Endgame: A Critique of Policy Proposals Aimed at Ending Tobacco Use. Tobacco Endgame Supplement of the Journal Tobacco Control. 2015.
8. Bates, C., Wade, C., Reducing Nicotine in Cigarettes: Challenges and Opportunities. 2017, R Street.
9. Baum, W.M., On two types of deviation from the matching law: bias and undermatching. J. Exp. Anal. Behav. 22:1 (1974), 231–242.
10. Bean, S.T., Smith, M.J., Victimless vapour? Health care organizations should restrict the use of e-cigarettes. Can. J. Public Health 106:8 (2016), e467–9.
11. Beard, E., et al. Association between electronic cigarette use and changes in quit attempts, success of quit attempts, use of smoking cessation pharmacotherapy, and use of stop smoking services in England: time series analysis of population trends. BMJ, 354, 2016, i4645.
12. Benowitz, N.L., Henningfield, J.E., Establishing a nicotine threshold for addiction. The implications for tobacco regulation. N. Engl. J. Med. 331:2 (1994), 123–125.
13. Benowitz, N.L., et al. Smokers of low-yield cigarettes do not consume less nicotine. N. Engl. J. Med. 309:3 (1983), 139–142.
14. Benowitz, N.L., et al. Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes. Cancer Epidemiol. Biomark. Prev. 21:5 (2012), 761–769.
15. Bickel, W.K., Marsch, L.A., Toward a behavioral economic understanding of drug dependence: delay discounting processes. Addiction 96:1 (2001), 73–86.
16. Blackford, A.L., et al. Cotinine concentration in smokers from different countries: relationship with amount smoked and cigarette type. Cancer Epidemiol. Biomark. Prev. 15:10 (2006), 1799–1804.
17. Blank, M.D., Eissenberg, T., Commentary on Brose et al. (2015): protecting individual and public health by regulating electronic cigarette nicotine delivery. Addiction 110:7 (2015), 1169–1170.
18. Bold, K.W., et al. Trajectories of E-cigarette and conventional cigarette use among youth. Pediatrics, 141(1), 2018 (Jan, pii: e20171832).
19. Brandon, T.H., Wetter, D.W., Baker, T.B., Affect, expectancies, urges, and smoking: do they conform to models of drug motivation and relapse?. Exp. Clin. Psychopharmacol. 4:1 (1996), 29–36.
20. Breslau, N., et al. Nicotine dependence in the United States: prevalence, trends, and smoking persistence. Arch. Gen. Psychiatry 58:9 (2001), 810–816.
21. Brown, J., et al. Real-world effectiveness of e-cigarettes when used to aid smoking cessation: a cross-sectional population study. Addiction 109:9 (2014), 1531–1540.
22. Bullen, C., et al. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 382:9905 (2013), 1629–1637.
23. Caggiula, A.R., et al. The role of nicotine in smoking: a dual-reinforcement model. Neb. Symp. Motiv. 55 (2009), 91–109.
24. Carpenter, M., et al. A naturalistic, randomized pilot trial of E-cigarettes: uptake, exposure, and behavioral effects. Cancer Epidemiol. Biomark. Prev. 26:12 (2017), 1795–1803 (Dec).
25. Carter, B.L., Tiffany, S.T., The cue-availability paradigm: the effects of cigarette availability on cue reactivity in smokers. Exp. Clin. Psychopharmacol. 9:2 (2001), 183–190.
26. Centers for Disease Control and Prevention, Quitting smoking among adults—United States, 2001–2010. MMWR Morb. Mortal. Wkly Rep. 60:44 (2011), 1513–1519.
27. Choi, J.J., et al. Defined contribution pensions: plan rules, participant decisions, and the path of least resistance. Poterba, J.M., (eds.) Tax Policy and the Economy, 2002, MIT Press, Cambridge, MA, 67–113.
28. Connolly, G.N., et al. Public attitudes regarding banning of cigarettes and regulation of nicotine. Am. J. Public Health 102:4 (2012), e1–2.
29. Cowie, G.A., et al. Cigarette brand loyalty in Australia: findings from the ITC four country survey. Tob. Control. 23:Suppl. 1 (2014), i73–9.
30. Czogala, J., et al. Secondhand exposure to vapors from electronic cigarettes. Nicotine Tob. Res. 16:6 (2014), 655–662.
31. Denlinger-Apte, R., et al. Acceptability of a Reduced Nicotine Product Standard for Cigarettes among Smokers Provided with Reduced Nicotine Cigarettes for Six Weeks. 2017, Society for Research on Nicotine and Tobacco Symposium Abstract.
32. Dias-Ferreira, E., et al. Chronic stress causes frontostriatal reorganization and affects decision-making. Science 325:5940 (2009), 621–625.
33. Donny, E.C., Dierker, L.C., The absence of DSM-IV nicotine dependence in moderate-to-heavy daily smokers. Drug Alcohol Depend. 89:1 (2007), 93–96.
34. Donny, E.C., Houtsmuller, E., Stitzer, M.L., Smoking in the absence of nicotine: behavioral, subjective and physiological effects over 11 days. Addiction 102:2 (2007), 324–334.
35. Donny, E.C., et al. Reduced nicotine product standards for combustible tobacco: building an empirical basis for effective regulation. Prev. Med. 68 (2014), 17–22.
36. Donny, E.C., et al. Randomized trial of reduced-nicotine standards for cigarettes. N. Engl. J. Med. 373:14 (2015), 1340–1349.
37. Donny, E.C., et al. Reducing the nicotine content of combusted tobacco products sold in New Zealand. Tob. Control. 26:e1 (2017), e37–e42.
38. Eriksen, M., et al. The Tobacco Atlas. Fifth Edition, 2015, American Cancer Society and World Lung Foundation.
39. Etter, J.F., Gateway effects and electronic cigarettes. Addiction, 2017, 10.1111/add.13924 (Aug 7, Epub ahead of print, PMID: 28786147).
40. Fagerstrom, K., Eissenberg, T., Dependence on tobacco and nicotine products: a case for product-specific assessment. Nicotine Tob. Res. 14:11 (2012), 1382–1390.
41. Farsalinos, K.E., et al. Electronic cigarette use in the European Union: analysis of a representative sample of 27,460 Europeans from 28 countries. Addiction 111:11 (2016), 2032–2040.
42. FDA, Philip Morris Products S.A. Modified Risk Tobacco Product (MRTP) Applications. [December 26, 2017]; Available from https://www.fda.gov/TobaccoProducts/Labeling/MarketingandAdvertising/ucm546281.htm, 2017.
43. Fix, B.V., et al. Smokers' reactions to FDA regulation of tobacco products: findings from the 2009 ITC United States survey. BMC Public Health, 11, 2011, 941.
44. Fojtik, B., U.S., FDA Can Learn From Japan How to Reduce Smoking. [December, 26, 2017]; Available from https://www.huffingtonpost.com/entry/us-fda-can-learn-from-japan-how-to-reduce-smoking_us_5a395a92e4b0c12e6337b182?ncid=engmodushpmg00000006, 2017.
45. Food and Drug Administration, FDA Accounces Comprehensive Regulatory Place to Shift Trajectory of Tobacco-Related Disease, Death. 2017.
46. Glantz, S., Accumulating Evidence Suggests E-cigs 1/3 to 1/2 as Bad as Cigs (Maybe Higher). Glantz blog, 2016 (December 14, 2017).
47. Goldenson, N.I., et al. Associations of electronic cigarette nicotine concentration with subsequent cigarette smoking and vaping levels in adolescents. JAMA Pediatr. 171:12 (2017), 1192–1199, 10.1001/jamapediatrics.2017.3209 (Dec. 1).
48. Goniewicz, M.L., et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob. Control. 23:2 (2014), 133–139.
49. Goodwin, R.D., Keyes, K.M., Hasin, D.S., Changes in cigarette use and nicotine dependence in the United States: evidence from the 2001–2002 wave of the national epidemiologic survey of alcoholism and related conditions. Am. J. Public Health 99:8 (2009), 1471–1477.
50. Hajek, P., et al. Electronic cigarettes: review of use, content, safety, effects on smokers and potential for harm and benefit. Addiction 109:11 (2014), 1801–1810.
51. Harrell, P.T., et al. Expectancies for cigarettes, e-cigarettes, and nicotine replacement therapies among e-cigarette users (aka vapers). Nicotine Tob. Res. 17:2 (2015), 193–200.
52. Hatsukami, D.K., et al. Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation. Addiction 105:2 (2010), 343–355.
53. Hatsukami, D.K., et al. Nicotine reduction: strategic research plan. Nicotine Tob. Res. 15:6 (2013), 1003–1013.
54. Hatsukami, D.K., et al. Dose-response effects of spectrum research cigarettes. Nicotine Tob. Res. 15:6 (2013), 1113–1121.
55. Hatsukami, D.K., et al. Reduced nicotine content cigarettes and nicotine patch. Cancer Epidemiol. Biomark. Prev. 22:6 (2013), 1015–1024.
56. Hatsukami, D.K., et al. Compensatory smoking from gradual and immediate reduction in cigarette nicotine content. Cancer Epidemiol. Biomark. Prev. 24:2 (2015), 472–476.
57. Hecht, S.S., et al. Evaluation of toxicant and carcinogen metabolites in the urine of e-cigarette users versus cigarette smokers. Nicotine Tob. Res. 17:6 (2015), 704–709.
58. Henningfield, J.E., The tobacco endgame: it's all about behavior. Prev. Med. 68 (2014), 11–16.
59. Herrnstein, R.J., Relative and absolute strength of response as a function of frequency of reinforcement. J. Exp. Anal. Behav. 4 (1961), 267–272.
60. Herrnstein, R.J., On the law of effect. J. Exp. Anal. Behav. 13:2 (1970), 243–266.
61. Higgins, S.T., et al. Addiction potential of cigarettes with reduced nicotine content in populations with psychiatric disorders and other vulnerabilities to tobacco addiction. JAMA Psychiatry 74:10 (2017), 1056–1064.
62. Hitchman, S.C., et al. Associations between E-cigarette type, frequency of use, and quitting smoking: findings from a longitudinal online panel survey in great Britain. Nicotine Tob. Res. 17:10 (2015), 1187–1194, 10.1093/ntr/ntv078 (Oct, Epub 2015 Apr 20).
63. Hogarth, L., et al. Associative learning mechanisms underpinning the transition from recreational drug use to addiction. Ann. N. Y. Acad. Sci. 1282 (2013), 12–24.
64. Jamal, A., et al. Tobacco use among middle and high school students - United States, 2011–2016. MMWR Morb. Mortal. Wkly Rep. 66:23 (2017), 597–603.
65. Jo, C.L., et al. US consumer interest in non-cigarette tobacco products spikes around the 2009 federal tobacco tax increase. Tob. Control. 24:4 (2015), 395–399.
66. Kozlowski, L.T., Prospects for a nicotine-reduction strategy in the cigarette endgame: alternative tobacco harm reduction scenarios. Int. J. Drug Policy 26:6 (2015), 543–547.
67. Kozlowski, L.T., Cigarette prohibition and the need for more prior testing of the WHO TobReg's global nicotine-reduction strategy. Tob. Control. 26:e1 (2017), e31–e34, 10.1136/tobaccocontrol-2016-052995 (Mar, Epub 2016 Jun 29).
68. Kozlowski, L.T., Let actual markets help assess the worth of optional very-low-nicotine cigarettes before deciding on mandatory regulations. Addiction 112:1 (2017), 3–5.
69. Kozlowski, L.T., Abrams, D.B., Obsolete tobacco control themes can be hazardous to public health: the need for updating views on absolute product risks and harm reduction. BMC Public Health, 16, 2016, 432.
70. Kozlowski, L.T., O'Connor, R.J., Cigarette filter ventilation is a defective design because of misleading taste, bigger puffs, and blocked vents. Tob. Control. 11:Suppl. 1 (2002), I40–50.
71. Kozlowski, L.T., Warner, K.E., Adolescents and e-cigarettes: objects of concern may appear larger than they are. Drug Alcohol Depend. 174 (2017), 209–214.
72. Kozlowski, L.T., et al. Applying the risk/use equilibrium: use medicinal nicotine now for harm reduction. Tob. Control. 10:3 (2001), 201–203.
73. Kunze, U., et al. Alternative nicotine delivery systems (ANDS)–public health-aspects. Wien. Klin. Wochenschr. 110:23 (1998), 811–816.
74. Lanza, S.T., Russell, M.A., Braymiller, J.L., Emergence of electronic cigarette use in US adolescents and the link to traditional cigarette use. Addict. Behav. 67 (2017), 38–43.
75. Lee, P.N., Summary of the epidemiological evidence relating snus to health. Regul. Toxicol. Pharmacol. 59:2 (2011), 197–214.
76. Lee, P.N., The effect on health of switching from cigarettes to snus - a review. Regul. Toxicol. Pharmacol. 66:1 (2013), 1–5.
77. Leventhal, A.M., et al. Association of e-cigarette vaping and progression to heavier patterns of cigarette smoking. JAMA 316:18 (2016), 1918–1920.
78. Li, J., Newcombe, R., Walton, D., Responses towards additional tobacco control measures: data from a population-based survey of New Zealand adults. N. Z. Med. J. 129:1428 (2016), 87–92.
79. Loewenstein, G., Brennan, T., Volpp, K.G., Asymmetric paternalism to improve health behaviors. J. Am. Med. Assoc. 298:20 (2007), 2415–2417.
80. Loewenstein, G., et al. Can behavioural economics make us healthier?. BMJ, 344, 2012, e3482.
81. McDowell, J.J., Matching theory in natural human environments. Behav. Anal. 11:2 (1988), 95–109.
82. McDowell, J.J., On the classic and modern theories of matching. J. Exp. Anal. Behav. 84:1 (2005), 111–127.
83. McNeill, A., et al. E-cigarettes: An Evidence Uptake. A Report Commissioned by Public Health England. 2015, Public Health England, London.
84. McRobbie, H., et al. Electronic cigarettes for smoking cessation and reduction. Cochrane Database Syst. Rev., 12, 2014, CD010216.
85. Mercincavage, M., et al. A randomized controlled trial of progressively reduced nicotine content cigarettes on smoking behaviors, biomarkers of exposure, and subjective ratings. Cancer Epidemiol. Biomark. Prev. 25:7 (2016), 1125–1133.
86. Mercincavage, M., et al. Attrition during a randomized controlled trial of reduced nicotine content cigarettes as a proxy for understanding acceptability of nicotine product standards. Addiction 112:6 (2017), 1095–1103.
87. Miller, M.E., et al. Electronic cigarette expectancies in smokers with psychological distress. Tob. Regul. Sci. 3:1 (2017), 108–114.
88. National Academy of Sciences, Engineering, and Medicine, Public Health Consequences of E-cigarettes. 2018, The National Academicis Press, Washington, DC.
89. Nuffield Council on Bioethics, Public Health: Ethical Issues. 2007, Cambridge Publishers Ltd, London.
90. Nutt, D.J., et al. Estimating the harms of nicotine-containing products using the MCDA approach. Eur. Addict. Res. 20:5 (2014), 218–225.
91. O'Donoghue, T., Rabin, M., Doing it now or later. Am. Econ. Rev. 89:1 (1999), 103–124.
92. Pacek, L.R., et al. Perceived nicotine content of reduced nicotine content cigarettes is a correlate of perceived health risks. Tob. Control., 2017, 10.1136/tobaccocontrol-2017-053689 (Jul 22, pii: tobaccocontrol-2017-053689, Epub ahead of print).
93. Pearson, J.L., et al. Public support for mandated nicotine reduction in cigarettes. Am. J. Public Health 103:3 (2013), 562–567.
94. Primack, B.A., et al. Progression to traditional cigarette smoking after electronic cigarette use among US adolescents and young adults. JAMA Pediatr. 169:11 (2015), 1018–1023.
95. Primack, B.A., et al. Initiation of traditional cigarette smoking after electronic cigarette use among tobacco-naive U.S. young adults. Am. J. Med., 131(4), 2018, 10.1016/j.amjmed.2017.11.005 (e1-443.e9, Apr, Epub 2017 Dec 11).
96. Proctor, R.N., Golden Holocaust: Origins of the Cigarette Catastrophe and the Case for Abolition. 2011, University of California Press, Berkeley, Los Angeles, London.
97. Reuter, P., Can tobacco control endgame analysis learn anything from the US experience with illegal drugs?. Tob. Control. 22:Suppl. 1 (2013), i49–51.
98. Robinson, T.E., Berridge, K.C., Incentive-sensitization and addiction. Addiction 96:1 (2001), 103–114.
99. Ross, K.C., Juliano, L.M., Perceived smoking availability differentially affects mood and reaction time. Addict. Behav. 45 (2015), 234–238.
100. Rupprecht, L.E., et al. Behavioral mechanisms underlying nicotine reinforcement. Curr. Top. Behav. Neurosci. 24 (2015), 19–53.
101. Saitta, D., et al. A risk assessment matrix for public health principles: the case for E-cigarettes. Int. J. Environ. Res. Public Health, 14(4), 2017.
102. Scherer, G., Smoking behaviour and compensation: a review of the literature. Psychopharmacology 145:1 (1999), 1–20.
103. Shields, P.G., Long-term nicotine replacement therapy: cancer risk in context. Cancer Prev. Res. (Phila.) 4:11 (2011), 1719–1723.
104. Smith, T.T., et al. Impact of smoking reduced nicotine content cigarettes on sensitivity to cigarette price: further results from a multi-site clinical trial. Addiction 112:2 (2017), 349–359.
105. Soneji, S., et al. Association between initial use of e-cigarettes and subsequent cigarette smoking among adolescents and young adults: a systematic review and meta-analysis. JAMA Pediatr. 171:8 (2017), 788–797.
106. Stanwick, R., E-cigarettes: are we renormalizing public smoking? Reversing five decades of tobacco control and revitalizing nicotine dependency in children and youth in Canada. Paediatr. Child Health 20:2 (2015), 101–105.
107. Sweanor, D., Alcabes, P., Drucker, E., Tobacco harm reduction: how rational public policy could transform a pandemic. Int. J. Drug Policy 18:2 (2007), 70–74.
108. The Surgeon General, The Health Consequences of Smoking-50 Years of Progress: A Report of the Surgeon General. 2014 (Atlanta (GA)).
109. Tiffany, S.T., A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. Psychol. Rev. 97:2 (1990), 147–168.
110. Tiffany, S.T., Conklin, C.A., A cognitive processing model of alcohol craving and compulsive alcohol use. Addiction 95:Suppl. 2 (2000), S145–53.
111. Tobacco Meets Technology, [December 26, 2017]; Available from https://www.pmi.com/smoke-free-products/iqos-our-tobacco-heating-system, 2017.
112. US Departmenf of Health and Human Services, The Health Consequences of Smoking: Nicotine Addiction: A Report of the Surgeon General. 1988.
113. US Department of Health and Human Services, How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Sugeon General. 2010, Dept. of Health and Human Services, Rockville, MD.
114. Warner, K.E., Pollack, H.A., The Nicotine Fix, in The Atlantic. 2014 (United States).
115. West, R., Shahab, L., Brown, J., Estimating the population impact of e-cigarettes on smoking cessation in England. Addiction 111:6 (2016), 1118–1119.
116. Wilson, S.J., Sayette, M.A., Fiez, J.A., Quitting-unmotivated and quitting-motivated cigarette smokers exhibit different patterns of cue-elicited brain activation when anticipating an opportunity to smoke. J. Abnorm. Psychol. 121:1 (2012), 198–211.
117. Wilson, S.J., et al. Instructed smoking expectancy modulates cue-elicited neural activity: a preliminary study. Nicotine Tob. Res. 7:4 (2005), 637–645.
118. World Health Organization, WHO Global Report on Trends in Prevalence of Tobacco Smoking 2015. 2015, WHO Library Cataloguing.
119. World Health Organization, WHO Report on the Global Tobacco Epidemic. 2015, 2015.
120. World Health Organization, WHO Study Group on Tobacco Product Regulation: Report on the Scientific Basis of Tobacco Product Regulation: Fifth Report of a WHO Study Group. WHO Technical Report Series, 2015, World Health Organization, Geneva.
121. Zacny, J.P., Stitzer, M.L., Cigarette brand-switching: effects on smoke exposure and smoking behavior. J. Pharmacol. Exp. Ther. 246:2 (1988), 619–627.
122. Zeller, M., Hatsukami, D., G. Strategic Dialogue on Tobacco Harm Reduction, The Strategic Dialogue on Tobacco Harm Reduction: a vision and blueprint for action in the US. Tob. Control. 18:4 (2009), 324–332.
123. Zhu, S.H., et al. E-cigarette use and associated changes in population smoking cessation: evidence from US current population surveys. BMJ, 358, 2017, j3262.