Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

Cell

Volumn 173, Issue 2, 2018, Pages 291-304.e6

  Hoadley, Katherine A ^a,s   Yau, Christina ^b,c   Hinoue, Toshinori ^d   Wolf, Denise M ^c   Lazar, Alexander J ^e,s   Drill, Esther ^f   Shen, Ronglai ^f   Taylor, Alison M ^g,h   Cherniack, Andrew D ^g,h,s   Thorsson, Vésteinn ⁱ   Akbani, Rehan ^e   Bowlby, Reanne ^j   Wong, Christopher K ^k   Wiznerowicz, Maciej ^l,m,n   Sanchez Vega, Francisco ^f   Robertson, A Gordon ^j,s   Schneider, Barbara G ^o   Lawrence, Michael S ^g,p,s   Noushmehr, Houtan ^q,r   Malta, Tathiane M ^q,r   Caesar Johnson, Samantha J ^s   Demchok, John A ^s   Felau, Ina ^s   Kasapi, Melpomeni ^s   Ferguson, Martin L ^s   Hutter, Carolyn M ^s   Sofia, Heidi J ^s   Tarnuzzer, Roy ^s   Wang, Zhining ^s   Yang, Liming ^s   Zenklusen, Jean C ^s   Stuart, Joshua M ^k   Laird, Peter W ^d   Benz, Christopher C ^b   more..

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VAN ANDEL RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h DANA FARBER CANCER INSTITUTE   (United States)

ⁱ INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^j BRITISH COLUMBIA CANCER AGENCY   (Canada)

^k University of California Santa Cruz   (United States)

^l POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^m GREATER POLAND CANCER CENTRE   (Poland)

ⁿ International Institute for Molecular Oncology   (Poland)

^o VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^p HARVARD MEDICAL SCHOOL   (United States)

^q HENRY FORD HEALTH SYSTEM   (United States)

^r UNIVERSITY OF SÃO PAULO   (Brazil)

^s Julia)

more..

Author keywords

cancer; cell of origin; genome; methylome; organs; proteome; subtypes; TCGA; tissues; transcriptome

Indexed keywords

DNA; MESSENGER RNA; MICRORNA; TUMOR PROTEIN;

ADULT; ANEUPLOIDY; ARTICLE; CELLS; CHROMOSOME; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DNA METHYLATION; FEMALE; FEMALE GENITAL TRACT CANCER; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN TISSUE; KIDNEY CANCER; MALE; MALIGNANT NEOPLASM; MICROARRAY ANALYSIS; MOLECULAR BIOLOGY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR CLASSIFICATION; CLUSTER ANALYSIS; CPG ISLAND; FACTUAL DATABASE; GENETICS; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY;

ANEUPLOIDY; CHROMOSOMES; CLUSTER ANALYSIS; CPG ISLANDS; DATABASES, FACTUAL; DNA METHYLATION; HUMANS; MICRORNAS; MUTATION; NEOPLASM PROTEINS; NEOPLASMS; RNA, MESSENGER;

EID: 85044737247     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.03.022     Document Type: Article

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