Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish

Developmental Cell

Volumn 44, Issue 4, 2018, Pages 433-446.e7

  González Rosa, Juan Manuel ^a,b   Sharpe, Michka ^a,b   Field, Dorothy ^c   Soonpaa, Mark H ^c   Field, Loren J ^c   Burns, Caroline E ^a,b,d   Burns, C Geoffrey ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

cardiomyocyte; cardiomyocyte proliferation; heart regeneration; polyploidization; zebrafish

Indexed keywords

PROTEIN DERIVATIVE; PROTEIN ECT2; UNCLASSIFIED DRUG; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL FUNCTION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINESIS; DIPLOIDY; EMBRYO; MONONUCLEAR CELL; MOUSE; NONHUMAN; POLYPLOIDY; PRIORITY JOURNAL; TISSUE REGENERATION; UPREGULATION; ZEBRA FISH; ANIMAL; CELL CULTURE; CYTOLOGY; EMBRYOLOGY; GENETICS; HEART; HEART INFARCTION; METABOLISM; PATHOLOGY; PHYSIOLOGY; REGENERATION; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL PROLIFERATION; CELLS, CULTURED; HEART; MYOCARDIAL INFARCTION; MYOCARDIUM; POLYPLOIDY; REGENERATION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 85044661250     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2018.01.021     Document Type: Article

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