Polyploidization and cell fusion contribute to wound healing in the adult Drosophila epithelium

Current Biology

Volumn 23, Issue 22, 2013, Pages 2224-2232

  Losick, Vicki P ^a   Fox, Donald T ^b   Spradling, Allan C ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; DROSOPHILA PROTEIN; HPO PROTEIN, DROSOPHILA; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; RAC PROTEIN; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN; YORKIE PROTEIN, DROSOPHILA;

ABDOMINAL INJURY; AGE; ANIMAL; ARTICLE; CELL CYCLE; CELL FUSION; CYTOLOGY; DROSOPHILA; EPITHELIUM CELL; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; POLYPLOIDY; TRANSGENIC ANIMAL; WOUND HEALING;

ABDOMINAL INJURIES; AGE FACTORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL CYCLE; CELL FUSION; CYCLIN E; DROSOPHILA; DROSOPHILA PROTEINS; EPITHELIAL CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NUCLEAR PROTEINS; POLYPLOIDY; PROTEIN-SERINE-THREONINE KINASES; RAC GTP-BINDING PROTEINS; TRANS-ACTIVATORS; WOUND HEALING;

EID: 84889078273     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2013.09.029     Document Type: Article

References (50)

1. W. Razzell, W. Wood, and P. Martin Swatting flies: modelling wound healing and inflammation in Drosophila Dis. Model. Mech. 4 2011 569 574
2. M.J. Galko, and M.A. Krasnow Cellular and genetic analysis of wound healing in Drosophila larvae PLoS Biol. 2 2004 E239
3. M. Rämet, R. Lanot, D. Zachary, and P. Manfruelli JNK signaling pathway is required for efficient wound healing in Drosophila Dev. Biol. 241 2002 145 156
4. Z. Wang, C. Wilhelmsson, P. Hyrsl, T.G. Loof, P. Dobes, M. Klupp, O. Loseva, M. Mörgelin, J. Iklé, and R.M. Cripps Pathogen entrapment by transglutaminase - a conserved early innate immune mechanism PLoS Pathog. 6 2010 e1000763
5. H. Tang Regulation and function of the melanization reaction in Drosophila Fly (Austin) 3 2009 105 111
6. M.T. Abreu-Blanco, J.M. Verboon, R. Liu, J.J. Watts, and S.M. Parkhurst Drosophila embryos close epithelial wounds using a combination of cellular protrusions and an actomyosin purse string J. Cell Sci. 125 2012 5984 5997
7. W. Wood, A. Jacinto, R. Grose, S. Woolner, J. Gale, C. Wilson, and P. Martin Wound healing recapitulates morphogenesis in Drosophila embryos Nat. Cell Biol. 4 2002 907 912
8. S.H. Baek, H.W. Cho, Y.C. Kwon, J.H. Lee, M.J. Kim, H. Lee, and K.M. Choe Requirement for Pak3 in Rac1-induced organization of actin and myosin during Drosophila larval wound healing FEBS Lett. 586 2012 772 777
9. S.H. Baek, Y.C. Kwon, H. Lee, and K.M. Choe Rho-family small GTPases are required for cell polarization and directional sensing in Drosophila wound healing Biochem. Biophys. Res. Commun. 394 2010 488 492
10. C. Lesch, J. Jo, Y. Wu, G.S. Fish, and M.J. Galko A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes Genetics 186 2010 943 957
11. Y. Wu, A.R. Brock, Y. Wang, K. Fujitani, R. Ueda, and M.J. Galko A blood-borne PDGF/VEGF-like ligand initiates wound-induced epidermal cell migration in Drosophila larvae Curr. Biol. 19 2009 1473 1477
12. Y. Shirakata, R. Kimura, D. Nanba, R. Iwamoto, S. Tokumaru, C. Morimoto, K. Yokota, M. Nakamura, K. Sayama, and E. Mekada Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing J. Cell Sci. 118 2005 2363 2370
13. S. Werner, H. Smola, X. Liao, M.T. Longaker, T. Krieg, P.H. Hofschneider, and L.T. Williams The function of KGF in morphogenesis of epithelium and reepithelialization of wounds Science 266 1994 819 822
14. K.A. Mace, J.C. Pearson, and W. McGinnis An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head Science 308 2005 381 385
15. J.C. Pearson, M.T. Juarez, M. Kim, O. Drivenes, and W. McGinnis Multiple transcription factor codes activate epidermal wound-response genes in Drosophila Proc. Natl. Acad. Sci. USA 106 2009 2224 2229
16. S.B. Ting, J. Caddy, N. Hislop, T. Wilanowski, A. Auden, L.L. Zhao, S. Ellis, P. Kaur, Y. Uchida, and W.M. Holleran A homolog of Drosophila grainy head is essential for epidermal integrity in mice Science 308 2005 411 413
17. P. Angel, A. Szabowski, and M. Schorpp-Kistner Function and regulation of AP-1 subunits in skin physiology and pathology Oncogene 20 2001 2413 2423
18. K.A. Bielefeld, S. Amini-Nik, and B.A. Alman Cutaneous wound healing: recruiting developmental pathways for regeneration Cell. Mol. Life Sci. 70 2013 2059 2081
19. K. Schlegelmilch, M. Mohseni, O. Kirak, J. Pruszak, J.R. Rodriguez, D. Zhou, B.T. Kreger, V. Vasioukhin, J. Avruch, T.R. Brummelkamp, and F.D. Camargo Yap1 acts downstream of α-catenin to control epidermal proliferation Cell 144 2011 782 795
20. I. Bernascone, and F. Martin-Belmonte Crossroads of Wnt and Hippo in epithelial tissues Trends Cell Biol. 23 2013 380 389
21. M.V. Plikus, D.L. Gay, E. Treffeisen, A. Wang, R.J. Supapannachart, and G. Cotsarelis Epithelial stem cells and implications for wound repair Semin. Cell Dev. Biol. 23 2012 946 953
22. V.P. Losick, L.X. Morris, D.T. Fox, and A. Spradling Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation Dev. Cell 21 2011 159 171
23. H. Jiang, and B.A. Edgar Intestinal stem cells in the adult Drosophila midgut Exp. Cell Res. 317 2011 2780 2788
24. D.T. Fox, and A.C. Spradling The Drosophila hindgut lacks constitutively active adult stem cells but proliferates in response to tissue damage Cell Stem Cell 5 2009 290 297
25. M.I. Worley, L. Setiawan, and I.K. Hariharan Regeneration and transdetermination in Drosophila imaginal discs Annu. Rev. Genet. 46 2012 289 310
26. B. Zhao, K. Tumaneng, and K.L. Guan The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal Nat. Cell Biol. 13 2011 877 883
27. J.J. Fernandes, K.B. Atreya, K.M. Desai, R.E. Hall, M.D. Patel, A.A. Desai, A.E. Benham, J.L. Mable, and J.L. Straessle A dominant negative form of Rac1 affects myogenesis of adult thoracic muscles in Drosophila Dev. Biol. 285 2005 11 27
28. D.S. Andersen, J. Colombani, and P. Léopold Coordination of organ growth: principles and outstanding questions from the world of insects Trends Cell Biol. 23 2013 336 344
29. D.T. Fox, and R.J. Duronio Endoreplication and polyploidy: insights into development and disease Development 140 2013 3 12
30. B.A. Edgar, and P.H. O'Farrell Genetic control of cell division patterns in the Drosophila embryo Cell 57 1989 177 187
31. R.C. King Ovarian Development in Drosophila melanogaster 1970 Academic Press New York
32. Y. Tamori, and W.M. Deng Tissue repair through cell competition and compensatory cellular hypertrophy in postmitotic epithelia Dev. Cell 25 2013 350 363
33. D.T. Fox, J.G. Gall, and A.C. Spradling Error-prone polyploid mitosis during normal Drosophila development Genes Dev. 24 2010 2294 2302
34. M.K. Diril, C.K. Ratnacaram, V.C. Padmakumar, T. Du, M. Wasser, V. Coppola, L. Tessarollo, and P. Kaldis Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration Proc. Natl. Acad. Sci. USA 109 2012 3826 3831
35. M.C. Schroeder, and G. Halder Regulation of the Hippo pathway by cell architecture and mechanical signals Semin. Cell Dev. Biol. 23 2012 803 811
36. A.R. Brock, D.T. Babcock, and M.J. Galko Active cop, passive cop: developmental stage-specific modes of wound-induced blood cell recruitment in Drosophila Fly (Austin) 2 2008 303 305
37. J.V. Cordeiro, and A. Jacinto The role of transcription-independent damage signals in the initiation of epithelial wound healing Nat. Rev. Mol. Cell Biol. 14 2013 249 262
38. S. Adachi, K. Minamisawa, Y. Okushima, S. Inagaki, K. Yoshiyama, Y. Kondou, E. Kaminuma, M. Kawashima, T. Toyoda, and M. Matsui Programmed induction of endoreduplication by DNA double-strand breaks in Arabidopsis Proc. Natl. Acad. Sci. USA 108 2011 10004 10009
39. K.R. Machlus, and J.E. Italiano Jr. The incredible journey: From megakaryocyte development to platelet formation J. Cell Biol. 201 2013 785 796
40. M.J. Allen, T.A. Godenschwege, M.A. Tanouye, and P. Phelan Making an escape: development and function of the Drosophila giant fibre system Semin. Cell Dev. Biol. 17 2006 31 41
41. M.M. Parast, S. Aeder, and A.E. Sutherland Trophoblast giant-cell differentiation involves changes in cytoskeleton and cell motility Dev. Biol. 230 2001 43 60
42. A. Patel, and P.R. Dash Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation Eur. J. Cell Biol. 91 2012 171 179
43. B. Li, and J.H.C. Wang Fibroblasts and myofibroblasts in wound healing: force generation and measurement J. Tissue Viability 20 2011 108 120
44. X. Trepat, and J.J. Fredberg Plithotaxis and emergent dynamics in collective cellular migration Trends Cell Biol. 21 2011 638 646
45. J.M. Reinke, and H. Sorg Wound repair and regeneration Eur. Surg. Res. 49 2012 35 43
46. K.T. Weber, Y. Sun, S.K. Bhattacharya, R.A. Ahokas, and I.C. Gerling Myofibroblast-mediated mechanisms of pathological remodelling of the heart Nat. Rev. Cardiol. 10 2013 15 26
47. S.E. Senyo, M.L. Steinhauser, C.L. Pizzimenti, V.K. Yang, L. Cai, M. Wang, T.D. Wu, J.L. Guerquin-Kern, C.P. Lechene, and R.T. Lee Mammalian heart renewal by pre-existing cardiomyocytes Nature 493 2013 433 436
48. M.A. Laflamme, and C.E. Murry Heart regeneration Nature 473 2011 326 335
49. A. Jenett, G.M. Rubin, T.T. Ngo, D. Shepherd, C. Murphy, H. Dionne, B.D. Pfeiffer, A. Cavallaro, D. Hall, and J. Jeter A GAL4-driver line resource for Drosophila neurobiology Cell Rep. 2 2012 991 1001
50. C.J. Evans, J.M. Olson, K.T. Ngo, E. Kim, N.E. Lee, E. Kuoy, A.N. Patananan, D. Sitz, P. Tran, and M.T. Do G-TRACE: rapid Gal4-based cell lineage analysis in Drosophila Nat. Methods 6 2009 603 605