-
1
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov, L.B. et al. (2013) Signatures of mutational processes in human cancer. Nature, 500, 415-421
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
-
2
-
-
84906303775
-
Mechanisms underlying mutational signatures in human cancers
-
Helleday, T. et al. (2014) Mechanisms underlying mutational signatures in human cancers. Nat. Rev. Genet., 15, 585-598
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 585-598
-
-
Helleday, T.1
-
3
-
-
84925497848
-
Hypermutation in human cancer genomes: footprints and mechanisms
-
Roberts, S.A. et al. (2014) Hypermutation in human cancer genomes: footprints and mechanisms. Nat. Rev. Cancer, 14, 786-800
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 786-800
-
-
Roberts, S.A.1
-
4
-
-
84924341659
-
The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas
-
Saraconi, G. et al. (2014) The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas. Genome Biol., 15, 417
-
(2014)
Genome Biol
, vol.15
, pp. 417
-
-
Saraconi, G.1
-
5
-
-
85018197468
-
APOBEC enzymes: mutagenic fuel for cancer evolution and heterogeneity
-
Swanton, C. et al. (2015) APOBEC enzymes: mutagenic fuel for cancer evolution and heterogeneity. Cancer Discov., 5, 704-712
-
(2015)
Cancer Discov
, vol.5
, pp. 704-712
-
-
Swanton, C.1
-
6
-
-
84883356320
-
Evidence for APOBEC3B mutagenesis in multiple human cancers
-
Burns, M.B. et al. (2013) Evidence for APOBEC3B mutagenesis in multiple human cancers. Nat. Genet., 45, 977-983
-
(2013)
Nat. Genet
, vol.45
, pp. 977-983
-
-
Burns, M.B.1
-
7
-
-
84940574759
-
An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers
-
Chan, K. et al. (2015) An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nat. Genet., 47, 1067-1072
-
(2015)
Nat. Genet
, vol.47
, pp. 1067-1072
-
-
Chan, K.1
-
8
-
-
60049100687
-
Powerful mutators lurking in the genome
-
Petit, V. et al. (2009) Powerful mutators lurking in the genome. Philos. Trans. R. Soc. Lond. B. Biol. Sci., 364, 705-715
-
(2009)
Philos. Trans. R. Soc. Lond. B. Biol. Sci
, vol.364
, pp. 705-715
-
-
Petit, V.1
-
9
-
-
0036200070
-
An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22
-
Jarmuz, A. et al. (2002) An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics, 79, 285-296
-
(2002)
Genomics
, vol.79
, pp. 285-296
-
-
Jarmuz, A.1
-
10
-
-
33745936652
-
An overview of cytidine deaminases
-
Navaratnam, N. et al. (2006) An overview of cytidine deaminases. Int. J. Hematol., 83, 195-200
-
(2006)
Int. J. Hematol
, vol.83
, pp. 195-200
-
-
Navaratnam, N.1
-
11
-
-
50349093233
-
The AID/APOBEC family of nucleic acid mutators
-
Conticello, S.G. (2008) The AID/APOBEC family of nucleic acid mutators. Genome Biol., 9, 229
-
(2008)
Genome Biol
, vol.9
, pp. 229
-
-
Conticello, S.G.1
-
12
-
-
84882593001
-
Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death
-
Mussil, B. et al. (2013) Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death. PLoS One, 8, e73641
-
(2013)
PLoS One
, vol.8
-
-
Mussil, B.1
-
13
-
-
79953194132
-
Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism
-
Suspène, R. et al. (2011) Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism. Proc. Natl. Acad. Sci. USA., 108, 4858-4863
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 4858-4863
-
-
Suspène, R.1
-
14
-
-
84869159477
-
APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells
-
Shinohara, M. et al. (2012) APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells. Sci. Rep., 2, 806
-
(2012)
Sci. Rep
, vol.2
, pp. 806
-
-
Shinohara, M.1
-
15
-
-
84899645475
-
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer
-
Nik-Zainal, S. et al. (2014) Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer. Nat. Genet., 46, 487-491
-
(2014)
Nat. Genet
, vol.46
, pp. 487-491
-
-
Nik-Zainal, S.1
-
16
-
-
34247623286
-
Population stratification of a common APOBEC gene deletion polymorphism
-
Kidd, J.M. et al. (2007) Population stratification of a common APOBEC gene deletion polymorphism. PLoS Genet., 3, e63
-
(2007)
PLoS Genet
, vol.3
-
-
Kidd, J.M.1
-
17
-
-
84923309215
-
A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3'UTR enhances chromosomal DNA damage
-
Caval, V. et al. (2014) A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3'UTR enhances chromosomal DNA damage. Nat. Commun., 5, 5129
-
(2014)
Nat. Commun
, vol.5
, pp. 5129
-
-
Caval, V.1
-
18
-
-
84876585078
-
A common deletion in the APOBEC3 genes and breast cancer risk
-
Long, J. et al. (2013) A common deletion in the APOBEC3 genes and breast cancer risk. J. Natl. Cancer Inst., 105, 573-579
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 573-579
-
-
Long, J.1
-
19
-
-
84904719180
-
APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women
-
Qi, G. et al. (2014) APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women. Tumour Biol., 35, 5723-5726
-
(2014)
Tumour Biol
, vol.35
, pp. 5723-5726
-
-
Qi, G.1
-
20
-
-
84969988140
-
Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation
-
Wen, W.X. et al. (2016) Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation. Breast Cancer Res., 18, 56
-
(2016)
Breast Cancer Res
, vol.18
, pp. 56
-
-
Wen, W.X.1
-
21
-
-
84885093727
-
APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry
-
Xuan, D. et al. (2013) APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry. Carcinogenesis, 34, 2240-2243
-
(2013)
Carcinogenesis
, vol.34
, pp. 2240-2243
-
-
Xuan, D.1
-
22
-
-
84953638836
-
Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population
-
Göhler, S. et al. (2016) Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population. J. Cancer Res. Clin. Oncol., 142, 273-276
-
(2016)
J. Cancer Res. Clin. Oncol
, vol.142
, pp. 273-276
-
-
Göhler, S.1
-
23
-
-
44949262835
-
Cohort profile: cohort of Norway (CONOR)
-
Naess, O. et al. (2008) Cohort profile: cohort of Norway (CONOR). Int. J. Epidemiol., 37, 481-485
-
(2008)
Int J. Epidemiol
, vol.37
, pp. 481-485
-
-
Naess, O.1
-
24
-
-
84930413360
-
Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon
-
Gansmo, L.B. et al. (2015) Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon. Int. J. Cancer, 137, 96-103
-
(2015)
Int. J. Cancer
, vol.137
, pp. 96-103
-
-
Gansmo, L.B.1
-
25
-
-
84963564563
-
MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk
-
Gansmo, L.B. et al. (2015) MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk. Cancer Med., 4, 1901-1907
-
(2015)
Cancer Med
, vol.4
, pp. 1901-1907
-
-
Gansmo, L.B.1
-
26
-
-
84968807183
-
Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate
-
Gansmo, L.B. et al. (2016) Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate. Oncotarget, 7, 28637-28646
-
(2016)
Oncotarget
, vol.7
, pp. 28637-28646
-
-
Gansmo, L.B.1
-
27
-
-
84987723048
-
MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer
-
Helwa, R. et al. (2016) MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer. Sci. Rep., 6, 33153
-
(2016)
Sci. Rep
, vol.6
, pp. 33153
-
-
Helwa, R.1
-
28
-
-
84988431028
-
Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBECsignature mutations in tumors
-
Middlebrooks, C.D. et al. (2016) Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBECsignature mutations in tumors. Nat. Genet., 48, 1330-1338
-
(2016)
Nat. Genet
, vol.48
, pp. 1330-1338
-
-
Middlebrooks, C.D.1
-
29
-
-
84943171338
-
A global reference for human genetic variation
-
Genomes Project, C., et al. (2015) A global reference for human genetic variation. Nature, 526, 68-74
-
(2015)
Nature
, vol.526
, pp. 68-74
-
-
Genomes Project, C.1
-
30
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond, G.L. et al. (2004) A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell, 119, 591-602
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
-
31
-
-
74849083374
-
Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis
-
Economopoulos, K.P. et al. (2010) Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis. Breast Cancer Res. Treat., 120, 211-216
-
(2010)
Breast Cancer Res. Treat
, vol.120
, pp. 211-216
-
-
Economopoulos, K.P.1
-
32
-
-
79751471610
-
The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
-
Knappskog, S. et al. (2011) The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians. Cancer Cell, 19, 273-282
-
(2011)
Cancer Cell
, vol.19
, pp. 273-282
-
-
Knappskog, S.1
-
33
-
-
84907998640
-
Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649)
-
Knappskog, S. et al. (2014) Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649). Oncotarget, 5, 8223-8234
-
(2014)
Oncotarget
, vol.5
, pp. 8223-8234
-
-
Knappskog, S.1
|