Lung disease phenotypes caused by overexpression of combinations of α-, β-, and γ-subunits of the epithelial sodium channel in mouse airways

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 314, Issue 2, 2018, Pages L318-L331

  Livraghi Butrico, Alessandra ^a   Wilkinson, Kristen J ^a   Volmer, Allison S ^a   Gilmore, Rodney C ^a   Rogers, Troy D ^a   Caldwell, Ray A ^d   Burns, Kimberlie A ^a   Esther, Charles R ^a,b   Mall, Marcus A ^c   Boucher, Richard C ^a   O’Neal, Wanda K ^a   Grubb, Barbara R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d Parion Sciences   (United States)

Author keywords

CCSP driven overexpression; Epithelial sodium transport; Mucociliary clearance; Mucus concentration; ; ; ENaC subunits

Indexed keywords

EPITHELIAL SODIUM CHANNEL; SCNN1B PROTEIN, MOUSE; SCNN1G PROTEIN, MOUSE;

AIRWAY; ALPHA CHAIN; ARTICLE; BACTERIAL LOAD; BETA CHAIN; BIOENERGY; DISEASE SEVERITY; FEMALE; FETUS; GAMMA SUBUNIT; GENE OVEREXPRESSION; HISTOPATHOLOGY; HYDRATION; LEUKOCYTE DIFFERENTIAL COUNT; LUNG DISEASE; LUNG LAVAGE; MOUSE; MUCUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN STRUCTURE; SODIUM ABSORPTION; ANIMAL; C3H MOUSE; C57BL MOUSE; GENETICS; METABOLISM; PATHOLOGY; PNEUMONIA; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION;

ANIMALS; EPITHELIAL SODIUM CHANNELS; LUNG DISEASES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; PHENOTYPE; PNEUMONIA; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION;

EID: 85043603150     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00382.2017     Document Type: Article

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