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Volumn 7, Issue , 2018, Pages

R-spondins can potentiate WNT signaling without LGRs

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR; PROTEIN SERINE THREONINE KINASE; PROTEOHEPARAN SULFATE; R SPONDIN; SECRETORY PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; WNT PROTEIN; THROMBOSPONDIN;

EID: 85043519684     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.33126     Document Type: Article
Times cited : (105)

References (37)
  • 2
    • 33745912405 scopus 로고    scopus 로고
    • A time- and cost-efficient system for high-level protein production in mammalian cells
    • Aricescu AR, Lu W, Jones EY. 2006. A time- and cost-efficient system for high-level protein production in mammalian cells. Acta Crystallographica Section D Biological Crystallography 62: 1243-1250. DOI: https://doi.org/10.1107/S0907444906029799
    • (2006) Acta Crystallographica Section D Biological Crystallography , vol.62 , pp. 1243-1250
    • Aricescu, A.R.1    Lu, W.2    Jones, E.Y.3
  • 3
    • 42549128765 scopus 로고    scopus 로고
    • R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
    • Bell SM, Schreiner CM, Wert SE, Mucenski ML, Scott WJ, Whitsett JA. 2008. R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. Development 135: 1049-1058. DOI: https://doi.org/10.1242/dev.013359
    • (2008) Development , vol.135 , pp. 1049-1058
    • Bell, S.M.1    Schreiner, C.M.2    Wert, S.E.3    Mucenski, M.L.4    Scott, W.J.5    Whitsett, J.A.6
  • 4
    • 79960990066 scopus 로고    scopus 로고
    • R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling
    • Carmon KS, Gong X, Lin Q, Thomas A, Liu Q. 2011. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. PNAS 108: 11452-11457. DOI: https://doi.org/10.1073/pnas. 1106083108
    • (2011) PNAS , vol.108 , pp. 11452-11457
    • Carmon, K.S.1    Gong, X.2    Lin, Q.3    Thomas, A.4    Liu, Q.5
  • 5
    • 84879160899 scopus 로고    scopus 로고
    • The structural basis of R-spondin recognition by LGR5 and RNF43
    • Chen PH, Chen X, Lin Z, Fang D, He X. 2013. The structural basis of R-spondin recognition by LGR5 and RNF43. Genes & Development 27: 1345-1350. DOI: https://doi.org/10.1101/gad.219915.113
    • (2013) Genes & Development , vol.27 , pp. 1345-1350
    • Chen, P.H.1    Chen, X.2    Lin, Z.3    Fang, D.4    He, X.5
  • 6
    • 84901426479 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycan as a cell-surface endocytosis receptor
    • Christianson HC, Belting M. 2014. Heparan sulfate proteoglycan as a cell-surface endocytosis receptor. Matrix Biology 35: 51-55. DOI: https://doi.org/10.1016/j.matbio.2013.10.004
    • (2014) Matrix Biology , vol.35 , pp. 51-55
    • Christianson, H.C.1    Belting, M.2
  • 7
    • 84907487414 scopus 로고    scopus 로고
    • Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
    • Clevers H, Loh KM, Nusse R. 2014. Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science 346: 1248012. DOI: https://doi.org/10.1126/science.1248012
    • (2014) Science , vol.346 , pp. 1248012
    • Clevers, H.1    Loh, K.M.2    Nusse, R.3
  • 10
    • 84893947796 scopus 로고    scopus 로고
    • The R-spondin/Lgr5/Rnf43 module: Regulator of Wnt signal strength
    • de Lau W, Peng WC, Gros P, Clevers H. 2014. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength. Genes & Development 28: 305-316. DOI: https://doi.org/10.1101/gad.235473.113
    • (2014) Genes & Development , vol.28 , pp. 305-316
    • de Lau, W.1    Peng, W.C.2    Gros, P.3    Clevers, H.4
  • 11
    • 84858111175 scopus 로고    scopus 로고
    • The R-spondin protein family
    • de Lau WB, Snel B, Clevers HC. 2012. The R-spondin protein family. Genome Biology 13: 242. DOI: https://doi.org/10.1186/gb-2012-13-3-242
    • (2012) Genome Biology , vol.13 , pp. 242
    • de Lau, W.B.1    Snel, B.2    Clevers, H.C.3
  • 13
    • 84989899660 scopus 로고    scopus 로고
    • Chromatin-Remodeling complex SWI/SNF controls multidrug resistance by transcriptionally regulating the drug efflux pump ABCB1
    • Dubey R, Lebensohn AM, Bahrami-Nejad Z, Marceau C, Champion M, Gevaert O, Sikic BI, Carette JE, Rohatgi R. 2016. Chromatin-Remodeling complex SWI/SNF controls multidrug resistance by transcriptionally regulating the drug efflux pump ABCB1. Cancer Research 76: 5810-5821. DOI: https://doi.org/10.1158/0008-5472.CAN-16-0716
    • (2016) Cancer Research , vol.76 , pp. 5810-5821
    • Dubey, R.1    Lebensohn, A.M.2    Bahrami-Nejad, Z.3    Marceau, C.4    Champion, M.5    Gevaert, O.6    Sikic, B.I.7    Carette, J.E.8    Rohatgi, R.9
  • 15
    • 84974662991 scopus 로고    scopus 로고
    • Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer
    • Hao H-X, Jiang X, Cong F. 2016. Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer. Cancers 8: 54. DOI: https://doi.org/10.3390/cancers8060054
    • (2016) Cancers , vol.8 , pp. 54
    • Hao, H.-X.1    Jiang, X.2    Cong, F.3
  • 18
    • 5044244757 scopus 로고    scopus 로고
    • R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
    • Kazanskaya O, Glinka A, del Barco Barrantes I, Stannek P, Niehrs C, Wu W. 2004. R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Developmental Cell 7: 525-534. DOI: https://doi.org/10.1016/j.devcel.2004.07.019
    • (2004) Developmental Cell , vol.7 , pp. 525-534
    • Kazanskaya, O.1    Glinka, A.2    del Barco Barrantes, I.3    Stannek, P.4    Niehrs, C.5    Wu, W.6
  • 19
    • 59149092731 scopus 로고    scopus 로고
    • The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development
    • Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG, Niehrs C. 2008. The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development 135: 3655-3664. DOI: https://doi.org/10.1242/dev.027284
    • (2008) Development , vol.135 , pp. 3655-3664
    • Kazanskaya, O.1    Ohkawara, B.2    Heroult, M.3    Wu, W.4    Maltry, N.5    Augustin, H.G.6    Niehrs, C.7
  • 24
    • 84927548248 scopus 로고    scopus 로고
    • 1D4: A versatile epitope tag for the purification and characterization of expressed membrane and soluble proteins
    • Molday LL, Molday RS. 2014. 1D4: a versatile epitope tag for the purification and characterization of expressed membrane and soluble proteins. Methods in Molecular Biology 1177: 1-15. DOI: https://doi.org/10.1007/978-1-4939-1034-2_1
    • (2014) Methods in Molecular Biology , vol.1177 , pp. 1-15
    • Molday, L.L.1    Molday, R.S.2
  • 26
    • 33744964431 scopus 로고    scopus 로고
    • Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
    • Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK. 2006. Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. Journal of Biological Chemistry 281: 13247-13257. DOI: https://doi.org/10.1074/jbc.M508324200
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 13247-13257
    • Nam, J.S.1    Turcotte, T.J.2    Smith, P.F.3    Choi, S.4    Yoon, J.K.5
  • 27
    • 33751547518 scopus 로고    scopus 로고
    • Dynamic expression of R-spondin family genes in mouse development
    • Nam JS, Turcotte TJ, Yoon JK. 2007b. Dynamic expression of R-spondin family genes in mouse development. Gene Expression Patterns 7: 306-312. DOI: https://doi.org/10.1016/j.modgep.2006.08.006
    • (2007) Gene Expression Patterns , vol.7 , pp. 306-312
    • Nam, J.S.1    Turcotte, T.J.2    Yoon, J.K.3
  • 28
    • 79952491185 scopus 로고    scopus 로고
    • Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis
    • Ohkawara B, Glinka A, Niehrs C. 2011. Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Developmental Cell 20: 303-314. DOI: https://doi.org/10. 1016/j.devcel.2011.01.006
    • (2011) Developmental Cell , vol.20 , pp. 303-314
    • Ohkawara, B.1    Glinka, A.2    Niehrs, C.3
  • 29
    • 0034730728 scopus 로고    scopus 로고
    • Cell surface heparan sulfate proteoglycans: Selective regulators of ligand-receptor encounters
    • Park PW, Reizes O, Bernfield M. 2000. Cell surface heparan sulfate proteoglycans: selective regulators of ligand-receptor encounters. Journal of Biological Chemistry 275: 29923-29926. DOI: https://doi.org/10.1074/jbc.R000008200
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 29923-29926
    • Park, P.W.1    Reizes, O.2    Bernfield, M.3
  • 30
    • 84879778870 scopus 로고    scopus 로고
    • Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5
    • Peng WC, de Lau W, Forneris F, Granneman JC, Huch M, Clevers H, Gros P. 2013. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5. Cell Reports 3: 1885-1892. DOI: https://doi.org/10.1016/j.celrep.2013.06.009
    • (2013) Cell Reports , vol.3 , pp. 1885-1892
    • Peng, W.C.1    de Lau, W.2    Forneris, F.3    Granneman, J.C.4    Huch, M.5    Clevers, H.6    Gros, P.7
  • 33
    • 84879189812 scopus 로고    scopus 로고
    • Structural basis for R-spondin recognition by LGR4/5/6 receptors
    • Wang D, Huang B, Zhang S, Yu X, Wu W, Wang X. 2013. Structural basis for R-spondin recognition by LGR4/5/6 receptors. Genes & Development 27: 1339-1344. DOI: https://doi.org/10.1101/gad.219360.113
    • (2013) Genes & Development , vol.27 , pp. 1339-1344
    • Wang, D.1    Huang, B.2    Zhang, S.3    Yu, X.4    Wu, W.5    Wang, X.6
  • 36
    • 84883468619 scopus 로고    scopus 로고
    • Crystal structures of Lgr4 and its complex with R-spondin1
    • Xu K, Xu Y, Rajashankar KR, Robev D, Nikolov DB. 2013. Crystal structures of Lgr4 and its complex with R-spondin1. Structure 21: 1683-1689. DOI: https://doi.org/10.1016/j.str.2013.07.001
    • (2013) Structure , vol.21 , pp. 1683-1689
    • Xu, K.1    Xu, Y.2    Rajashankar, K.R.3    Robev, D.4    Nikolov, D.B.5
  • 37
    • 84889570757 scopus 로고    scopus 로고
    • Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin
    • Zebisch M, Xu Y, Krastev C, MacDonald BT, Chen M, Gilbert RJ, He X, Jones EY. 2013. Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin. Nature Communications 4: 2787. DOI: https://doi.org/10.1038/ncomms3787
    • (2013) Nature Communications , vol.4 , pp. 2787
    • Zebisch, M.1    Xu, Y.2    Krastev, C.3    MacDonald, B.T.4    Chen, M.5    Gilbert, R.J.6    He, X.7    Jones, E.Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.