-
1
-
-
0023710312
-
Cholesterol and lipids in the risk of coronary artery disease\-The Framingham Heart Study
-
Castelli, W. P. Cholesterol and lipids in the risk of coronary artery disease\-The Framingham Heart Study. Can. J. Cardiol. 4 (Suppl. A), 5A-10A (1988).
-
(1988)
Can. J. Cardiol.
, vol.4
, pp. 5A-10A
-
-
Castelli, W.P.1
-
2
-
-
72949132104
-
Factors of risk in the development of coronary heart disease-six year follow-up experience the Framingham Study
-
Kannel, W. B., Dawber, T. R., Kagan, A., Revotskie, N. &Stokes, J. III Factors of risk in the development of coronary heart disease-six year follow-up experience. The Framingham Study. Ann. Intern. Med. 55, 33-50 (1961).
-
(1961)
Ann. Intern. Med.
, vol.55
, pp. 33-50
-
-
Kannel, W.B.1
Dawber, T.R.2
Kagan, A.3
Revotskie, N.4
Stokes, J.5
-
3
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
Willer, C. J. et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 45, 1274-1283 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
-
4
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
-
5
-
-
84955263526
-
Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs
-
Below, J. E. et al. Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. Sci. Rep. 6, 19429 (2016).
-
(2016)
Sci. Rep.
, vol.6
, pp. 19429
-
-
Below, J.E.1
-
6
-
-
84860014014
-
Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: The PAGE study
-
Buyske, S. et al. Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. PLoS One 7, e35651 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e35651
-
-
Buyske, S.1
-
7
-
-
84878828157
-
Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations
-
Coram, M. A. et al. Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. Am. J. Hum. Genet. 92, 904-916 (2013).
-
(2013)
Am. J. Hum. Genet.
, vol.92
, pp. 904-916
-
-
Coram, M.A.1
-
8
-
-
84870879275
-
Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations
-
Elbers, C. C. et al. Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. PLoS One 7, e50198 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e50198
-
-
Elbers, C.C.1
-
9
-
-
84885996384
-
THOC5: A novel gene involved in HDL-cholesterol metabolism
-
Keller, M. et al. THOC5: A novel gene involved in HDL-cholesterol metabolism. J. Lipid Res. 54, 3170-3176 (2013).
-
(2013)
J. Lipid Res.
, vol.54
, pp. 3170-3176
-
-
Keller, M.1
-
10
-
-
84901949893
-
Amerindian-specific regions under positive selection harbour new lipid variants in Latinos
-
Ko, A. et al. Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat. Commun. 5, 3983 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3983
-
-
Ko, A.1
-
11
-
-
84971330664
-
Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride
-
Kurano, M. et al. Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride. J. Hum. Genet. 61, 427-433 (2016).
-
(2016)
J. Hum. Genet.
, vol.61
, pp. 427-433
-
-
Kurano, M.1
-
12
-
-
84941003694
-
Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration
-
Lanktree, M. B. et al. Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration. J. Lipid Res. 56, 1781-1786 (2015).
-
(2015)
J. Lipid Res.
, vol.56
, pp. 1781-1786
-
-
Lanktree, M.B.1
-
13
-
-
84963837739
-
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels
-
van Leeuwen, E. M. et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. J. Med. Genet. 53, 441-449 (2016).
-
(2016)
J. Med. Genet.
, vol.53
, pp. 441-449
-
-
Van Leeuwen, E.M.1
-
14
-
-
84959476339
-
Genetic susceptibility to lipid levels and lipid change over time and risk of incident hyperlipidemia in Chinese populations
-
Lu, X. et al. Genetic susceptibility to lipid levels and lipid change over time and risk of incident hyperlipidemia in Chinese populations. Circ. Cardiovasc. Genet. 9, 37-44 (2016).
-
(2016)
Circ. Cardiovasc. Genet.
, vol.9
, pp. 37-44
-
-
Lu, X.1
-
15
-
-
84861307204
-
Multi-ethnic analysis of lipid-associated loci: The NHLBI CARe project
-
Musunuru, K. et al. Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. PLoS One 7, e36473 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e36473
-
-
Musunuru, K.1
-
16
-
-
84930090376
-
The impact of low-frequency and rare variants on lipid levels
-
Surakka, I. et al. The impact of low-frequency and rare variants on lipid levels. Nat. Genet. 47, 589-597 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 589-597
-
-
Surakka, I.1
-
17
-
-
84943182742
-
The UK10K project identifies rare variants in health and disease
-
UK10K Consortium
-
UK10K Consortium. The UK10K project identifies rare variants in health and disease. Nature 526, 82-90 (2015).
-
(2015)
Nature
, vol.526
, pp. 82-90
-
-
-
18
-
-
84875996758
-
Trans-ethnic fine-mapping of lipid loci identifies populationspecific signals and allelic heterogeneity that increases the trait variance explained
-
Wu, Y. et al. Trans-ethnic fine-mapping of lipid loci identifies populationspecific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet. 9, e1003379 (2013).
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003379
-
-
Wu, Y.1
-
19
-
-
84945370533
-
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers
-
Sidore, C. et al. Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers. Nat. Genet. 47, 1272-1281 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 1272-1281
-
-
Sidore, C.1
-
20
-
-
85014345453
-
Analysis with the exome array identifies multiple new independent variants in lipid loci
-
Kanoni, S. et al. Analysis with the exome array identifies multiple new independent variants in lipid loci. Hum. Mol. Genet. 25, 4094-4106 (2016).
-
(2016)
Hum. Mol. Genet.
, vol.25
, pp. 4094-4106
-
-
Kanoni, S.1
-
21
-
-
84925860386
-
Multiple associated variants increase the heritability explained for plasma lipids and coronary artery disease
-
Tada, H. et al. Multiple associated variants increase the heritability explained for plasma lipids and coronary artery disease. Circ. Cardiovasc. Genet. 7, 583-587 (2014).
-
(2014)
Circ. Cardiovasc. Genet.
, vol.7
, pp. 583-587
-
-
Tada, H.1
-
22
-
-
84884167819
-
Heritability of metabolic syndrome traits in a large population-based sample
-
van Dongen, J., Willemsen, G., Chen, W.-M., de Geus, E. J. C. &Boomsma, D. I. Heritability of metabolic syndrome traits in a large population-based sample. J. Lipid Res. 54, 2914-2923 (2013).
-
(2013)
J. Lipid Res.
, vol.54
, pp. 2914-2923
-
-
Van Dongen, J.1
Willemsen, G.2
Chen, W.-M.3
De Geus, E.J.C.4
Boomsma, D.I.5
-
23
-
-
84904048618
-
Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations
-
Ganesh, S. K. et al. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am. J. Hum. Genet. 95, 49-65 (2014).
-
(2014)
Am. J. Hum. Genet.
, vol.95
, pp. 49-65
-
-
Ganesh, S.K.1
-
24
-
-
84995494168
-
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
-
Hoffmann, T. J. et al. Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Nat. Genet. 49, 54-64 (2017).
-
(2017)
Nat. Genet.
, vol.49
, pp. 54-64
-
-
Hoffmann, T.J.1
-
25
-
-
84939422197
-
Characterizing race/ethnicity and genetic ancestry for 100,000 subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort
-
Banda, Y. et al. Characterizing race/ethnicity and genetic ancestry for 100,000 subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort. Genetics 200, 1285-1295 (2015).
-
(2015)
Genetics
, vol.200
, pp. 1285-1295
-
-
Banda, Y.1
-
26
-
-
84939426058
-
Genotyping informatics and quality control for 100,000 subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort
-
Kvale, M. N. et al. Genotyping informatics and quality control for 100,000 subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort. Genetics 200, 1051-1060 (2015).
-
(2015)
Genetics
, vol.200
, pp. 1051-1060
-
-
Kvale, M.N.1
-
27
-
-
81955167912
-
Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm
-
Hoffmann, T. J. et al. Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm. Genomics 98, 422-430 (2011).
-
(2011)
Genomics
, vol.98
, pp. 422-430
-
-
Hoffmann, T.J.1
-
28
-
-
79960700796
-
Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array
-
Hoffmann, T. J. et al. Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics 98, 79-89 (2011).
-
(2011)
Genomics
, vol.98
, pp. 79-89
-
-
Hoffmann, T.J.1
-
29
-
-
84924060689
-
Efficient Bayesian mixed-model analysis increases association power in large cohorts
-
Loh, P.-R. et al. Efficient Bayesian mixed-model analysis increases association power in large cohorts. Nat. Genet. 47, 284-290 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 284-290
-
-
Loh, P.-R.1
-
30
-
-
79955860273
-
Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
-
Han, B. &Eskin, E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet. 88, 586-598 (2011).
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 586-598
-
-
Han, B.1
Eskin, E.2
-
31
-
-
79959241413
-
Genomic inflation factors under polygenic inheritance
-
Yang, J. et al. Genomic inflation factors under polygenic inheritance. Eur. J. Hum. Genet. 19, 807-812 (2011).
-
(2011)
Eur. J. Hum. Genet.
, vol.19
, pp. 807-812
-
-
Yang, J.1
-
32
-
-
84921782559
-
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
-
Pasaniuc, B. et al. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics 30, 2906-2914 (2014).
-
(2014)
Bioinformatics
, vol.30
, pp. 2906-2914
-
-
Pasaniuc, B.1
-
33
-
-
84926430250
-
UK Biobank: An open access resource for identifying the causes of a wide range of complex diseases of middle and old age
-
Sudlow, C. et al. UK Biobank: An open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 12, e1001779 (2015).
-
(2015)
PLoS Med.
, vol.12
, pp. e1001779
-
-
Sudlow, C.1
-
34
-
-
33745700802
-
Assessing heterogeneity in meta-analysis: Q statistic or I2 index? Psychol
-
Huedo-Medina, T. B., Sánchez-Meca, J., Marín-Martínez, F. &Botella, J. Assessing heterogeneity in meta-analysis: Q statistic or I2 index? Psychol. Methods 11, 193-206 (2006).
-
(2006)
Methods
, vol.11
, pp. 193-206
-
-
Huedo-Medina, T.B.1
Sánchez-Meca, J.2
Marín-Martínez, F.3
Botella, J.4
-
35
-
-
0032747981
-
Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism
-
Sijbrands, E. J. G. et al. Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism. Arterioscler. Thromb. Vasc. Biol. 19, 2722-2729 (1999).
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2722-2729
-
-
Sijbrands, E.J.G.1
-
36
-
-
84898478242
-
Sex-specific association of the zinc finger protein 259 rs2075290 polymorphism and serum lipid levels
-
Aung, L. H. H. et al. Sex-specific association of the zinc finger protein 259 rs2075290 polymorphism and serum lipid levels. Int. J. Med. Sci. 11, 471-478 (2014).
-
(2014)
Int. J. Med. Sci.
, vol.11
, pp. 471-478
-
-
Aung, L.H.H.1
-
37
-
-
84954289735
-
Model-free estimation of recent genetic relatedness
-
Conomos, M. P., Reiner, A. P., Weir, B. S. &Thornton, T. A. Model-free estimation of recent genetic relatedness. Am. J. Hum. Genet. 98, 127-148 (2016).
-
(2016)
Am. J. Hum. Genet.
, vol.98
, pp. 127-148
-
-
Conomos, M.P.1
Reiner, A.P.2
Weir, B.S.3
Thornton, T.A.4
-
38
-
-
84901060300
-
Estimating heritability of complex traits from genome-wide association studies using IBS-based Haseman-Elston regression
-
Chen, G.-B. Estimating heritability of complex traits from genome-wide association studies using IBS-based Haseman-Elston regression. Stat. Genet. 5, 107 (2014).
-
(2014)
Stat. Genet.
, vol.5
, pp. 107
-
-
Chen, G.-B.1
-
39
-
-
78650856517
-
GCTA: A tool for genome-wide complex trait analysis
-
Yang, J., Lee, S. H., Goddard, M. E. &Visscher, P. M. GCTA: A tool for genome-wide complex trait analysis. Am. J. Hum. Genet. 88, 76-82 (2011).
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 76-82
-
-
Yang, J.1
Lee, S.H.2
Goddard, M.E.3
Visscher, P.M.4
-
40
-
-
84929001104
-
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
-
GTEx Consortium
-
GTEx Consortium. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 348, 648-660 (2015).
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
-
41
-
-
84947789021
-
-
(Wiley, Hoboken, NJ,)
-
Hosmer, D. &Lemeshow, S. Applied Survival Analysis: Regression Modeling of Time to Event Data (Wiley, Hoboken, NJ, 2008).
-
(2008)
Applied Survival Analysis: Regression Modeling of Time to Event Data
-
-
Hosmer, D.1
Lemeshow, S.2
-
42
-
-
49949104757
-
SLCO1B1 variants and statin-induced myopathy-A genomewide study
-
Link, E. et al. SLCO1B1 variants and statin-induced myopathy-A genomewide study. N. Engl. J. Med. 359, 789-799 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 789-799
-
-
Link, E.1
-
43
-
-
84864619335
-
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple loci implicated in sex steroid hormone regulation
-
Coviello, A. D. et al. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple loci implicated in sex steroid hormone regulation. PLoS Genet. 8, e1002805 (2012).
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002805
-
-
Coviello, A.D.1
-
44
-
-
67649838598
-
Genome-wide association meta-analysis for total serum bilirubin levels
-
Johnson, A. D. et al. Genome-wide association meta-analysis for total serum bilirubin levels. Hum. Mol. Genet. 18, 2700-2710 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2700-2710
-
-
Johnson, A.D.1
-
45
-
-
76749146910
-
PharmGKB very important pharmacogene: SLCO1B1
-
Oshiro, C., Mangravite, L., Klein, T. &Altman, R. PharmGKB very important pharmacogene: SLCO1B1. Pharmacogenet. Genomics 20, 211-216 (2010).
-
(2010)
Pharmacogenet. Genomics
, vol.20
, pp. 211-216
-
-
Oshiro, C.1
Mangravite, L.2
Klein, T.3
Altman, R.4
-
46
-
-
0040368659
-
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
-
Abe, T. et al. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J. Biol. Chem. 274, 17159-17163 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17159-17163
-
-
Abe, T.1
-
47
-
-
0033601257
-
A novel human hepatic organic anion transporting polypeptide (OATP2) Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
-
Hsiang, B. et al. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J. Biol. Chem. 274, 37161-37168 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37161-37168
-
-
Hsiang, B.1
-
48
-
-
80053102580
-
Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
-
Yu, E. A. &Weaver, D. R. Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes. Aging 3, 479-493 (2011).
-
(2011)
Aging
, vol.3
, pp. 479-493
-
-
Yu, E.A.1
Weaver, D.R.2
-
49
-
-
80053054824
-
Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation
-
Shimba, S. et al. Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation. PLoS One 6, e25231 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e25231
-
-
Shimba, S.1
-
50
-
-
84934932181
-
A metabolomic study of adipose tissue in mice with a disruption of the circadian system
-
Castro, C., Briggs, W., Paschos, G. K., FitzGerald, G. A. &Griffin, J. L. A metabolomic study of adipose tissue in mice with a disruption of the circadian system. Mol. Biosyst. 11, 1897-1906 (2015).
-
(2015)
Mol. Biosyst.
, vol.11
, pp. 1897-1906
-
-
Castro, C.1
Briggs, W.2
Paschos, G.K.3
FitzGerald, G.A.4
Griffin, J.L.5
-
51
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks, D. J. et al. Bile acids: natural ligands for an orphan nuclear receptor. Science 284, 1365-1368 (1999).
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
-
52
-
-
0028031001
-
Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates
-
Green, M. D., Oturu, E. M. &Tephly, T. R. Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug Metab. Dispos. 22, 799-805 (1994).
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 799-805
-
-
Green, M.D.1
Oturu, E.M.2
Tephly, T.R.3
-
53
-
-
0029809062
-
Isolation and characterization of a novel cDNA encoding a human UDPglucuronosyltransferase active on C19 steroids
-
Beaulieu, M., Lévesque, E., Hum, D. W. &Bélanger, A. Isolation and characterization of a novel cDNA encoding a human UDPglucuronosyltransferase active on C19 steroids. J. Biol. Chem. 271, 22855-22862 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22855-22862
-
-
Beaulieu, M.1
Lévesque, E.2
Hum, D.W.3
Bélanger, A.4
-
54
-
-
0037403749
-
Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics
-
Turgeon, D., Carrier, J.-S., Chouinard, S. &Bélanger, A. Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics. Drug Metab. Dispos. 31, 670-676 (2003).
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 670-676
-
-
Turgeon, D.1
Carrier, J.-S.2
Chouinard, S.3
Bélanger, A.4
-
55
-
-
84865626577
-
Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis
-
Liao, Y.-J. et al. Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis. Mol. Med. 18, 412-422 (2012).
-
(2012)
Mol. Med.
, vol.18
, pp. 412-422
-
-
Liao, Y.-J.1
-
56
-
-
36349011287
-
Glycine N-methyltransferase-/-mice develop chronic hepatitis and glycogen storage disease in the liver
-
Liu, S.-P. et al. Glycine N-methyltransferase-/-mice develop chronic hepatitis and glycogen storage disease in the liver. Hepatology 46, 1413-1425 (2007).
-
(2007)
Hepatology
, vol.46
, pp. 1413-1425
-
-
Liu, S.-P.1
-
57
-
-
84927126103
-
Cholesterol transport through lysosome-peroxisome membrane contacts
-
Chu, B.-B. et al. Cholesterol transport through lysosome-peroxisome membrane contacts. Cell 161, 291-306 (2015).
-
(2015)
Cell
, vol.161
, pp. 291-306
-
-
Chu, B.-B.1
-
58
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst, J. et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49 (2011).
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
-
59
-
-
84948761469
-
Glucagon receptor antagonism induces increased cholesterol absorption
-
Guan, H.-P. et al. Glucagon receptor antagonism induces increased cholesterol absorption. J. Lipid Res. 56, 2183-2195 (2015).
-
(2015)
J. Lipid Res.
, vol.56
, pp. 2183-2195
-
-
Guan, H.-P.1
-
60
-
-
84884407233
-
Fat depots, free fatty acids, and dyslipidemia
-
Ebbert, J. O. &Jensen, M. D. Fat depots, free fatty acids, and dyslipidemia. Nutrients 5, 498-508 (2013).
-
(2013)
Nutrients
, vol.5
, pp. 498-508
-
-
Ebbert, J.O.1
Jensen, M.D.2
-
61
-
-
78651507377
-
Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: A magnetic resonance imaging study
-
Hoenig, M. R., Cowin, G., Buckley, R., McHenery, C. &Coulthard, A. Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: A magnetic resonance imaging study. Lipids Health Dis. 10, 12 (2011).
-
(2011)
Lipids Health Dis.
, vol.10
, pp. 12
-
-
Hoenig, M.R.1
Cowin, G.2
Buckley, R.3
McHenery, C.4
Coulthard, A.5
-
62
-
-
55549147191
-
Personal genomes: The case of the missing heritability
-
Maher, B. Personal genomes: the case of the missing heritability. Nature 456, 18-21 (2008).
-
(2008)
Nature
, vol.456
, pp. 18-21
-
-
Maher, B.1
-
63
-
-
85007028930
-
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study
-
Dewey, F. E. et al. Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study. Science 354, aaf6814 (2016).
-
(2016)
Science
, vol.354
, pp. aaf6814
-
-
Dewey, F.E.1
-
64
-
-
84922421928
-
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
-
Lu, X. et al. Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. Hum. Mol. Genet. 24, 865-874 (2015).
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. 865-874
-
-
Lu, X.1
-
65
-
-
85035766416
-
Exome-wide association study of plasma lipids in ≥ 300,000 individuals
-
Liu, D. J. et al. Exome-wide association study of plasma lipids in ≥ 300,000 individuals. Nat. Genet. 49, 1758-1766 (2017).
-
(2017)
Nat. Genet.
, vol.49
, pp. 1758-1766
-
-
Liu, D.J.1
-
66
-
-
85035814059
-
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease
-
Lu, X. et al. Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. Nat. Genet. 49, 1722-1730 (2017).
-
(2017)
Nat. Genet.
, vol.49
, pp. 1722-1730
-
-
Lu, X.1
-
67
-
-
0015348189
-
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
-
Friedewald, W. T., Levy, R. I. &Fredrickson, D. S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502 (1972).
-
(1972)
Clin. Chem.
, vol.18
, pp. 499-502
-
-
Friedewald, W.T.1
Levy, R.I.2
Fredrickson, D.S.3
-
68
-
-
84856478855
-
A linear complexity phasing method for thousands of genomes
-
Delaneau, O., Marchini, J. &Zagury, J.-F. A linear complexity phasing method for thousands of genomes. Nat. Methods 9, 179-181 (2011).
-
(2011)
Nat. Methods
, vol.9
, pp. 179-181
-
-
Delaneau, O.1
Marchini, J.2
Zagury, J.-F.3
-
69
-
-
84863845193
-
Genotype imputation with thousands of genomes
-
Howie, B., Marchini, J. &Stephens, M. Genotype imputation with thousands of genomes. G3 1, 457-470 (2011).
-
(2011)
G3
, vol.1
, pp. 457-470
-
-
Howie, B.1
Marchini, J.2
Stephens, M.3
-
70
-
-
84864417548
-
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
-
Howie, B., Fuchsberger, C., Stephens, M., Marchini, J. &Abecasis, G. R. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat. Genet. 44, 955-959 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 955-959
-
-
Howie, B.1
Fuchsberger, C.2
Stephens, M.3
Marchini, J.4
Abecasis, G.R.5
-
71
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie, B. N., Donnelly, P. &Marchini, J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009).
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000529
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
72
-
-
77953808087
-
Genotype imputation for genome-wide association studies
-
Marchini, J. &Howie, B. Genotype imputation for genome-wide association studies. Nat. Rev. Genet. 11, 499-511 (2010).
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 499-511
-
-
Marchini, J.1
Howie, B.2
-
73
-
-
62649089065
-
Genotype-imputation accuracy across worldwide human populations
-
Huang, L. et al. Genotype-imputation accuracy across worldwide human populations. Am. J. Hum. Genet. 84, 235-250 (2009).
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 235-250
-
-
Huang, L.1
-
74
-
-
84989838868
-
Reference-based phasing using the Haplotype Reference Consortium panel
-
Loh, P.-R. et al. Reference-based phasing using the Haplotype Reference Consortium panel. Nat. Genet. 48, 1443-1448 (2016).
-
(2016)
Nat. Genet.
, vol.48
, pp. 1443-1448
-
-
Loh, P.-R.1
-
75
-
-
84984598118
-
Next-generation genotype imputation service and methods
-
Das, S. et al. Next-generation genotype imputation service and methods. Nat. Genet. 48, 1284-1287 (2016).
-
(2016)
Nat. Genet.
, vol.48
, pp. 1284-1287
-
-
Das, S.1
-
76
-
-
84865760395
-
GENCODE: The reference human genome annotation for the ENCODE Project
-
Harrow, J. et al. GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res. 22, 1760-1774 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1760-1774
-
-
Harrow, J.1
-
77
-
-
84858779229
-
HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
-
Ward, L. D. &Kellis, M. HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res. 40, D930-D934 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D930-D934
-
-
Ward, L.D.1
Kellis, M.2
-
78
-
-
77956534324
-
ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
-
Wang, K., Li, M. &Hakonarson, H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 38, e164 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. e164
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
79
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
Schadt, E. E. et al. Mapping the genetic architecture of gene expression in human liver. PLoS Biol. 6, e107 (2008).
-
(2008)
PLoS Biol.
, vol.6
, pp. e107
-
-
Schadt, E.E.1
-
80
-
-
84885018609
-
Systematic identification of trans eQTLs as putative drivers of known disease associations
-
Westra, H.-J. et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat. Genet. 45, 1238-1243 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1238-1243
-
-
Westra, H.-J.1
-
81
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
Lappalainen, T. et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature 501, 506-511 (2013).
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
-
82
-
-
79959916375
-
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
-
Greenawalt, D. M. et al. A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res. 21, 1008-1016 (2011).
-
(2011)
Genome Res.
, vol.21
, pp. 1008-1016
-
-
Greenawalt, D.M.1
-
83
-
-
79952489475
-
Estimating missing heritability for disease from genome-wide association studies
-
Lee, S. H., Wray, N. R., Goddard, M. E. &Visscher, P. M. Estimating missing heritability for disease from genome-wide association studies. Am. J. Hum. Genet. 88, 294-305 (2011).
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 294-305
-
-
Lee, S.H.1
Wray, N.R.2
Goddard, M.E.3
Visscher, P.M.4
-
84
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S. et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
85
-
-
84930213392
-
Second-generation PLINK: Rising to the challenge of larger and richer datasets
-
Chang, C. C. et al. Second-generation PLINK: rising to the challenge of larger and richer datasets. Gigascience 4, 7 (2015).
-
(2015)
Gigascience
, vol.4
, pp. 7
-
-
Chang, C.C.1
-
86
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
-
Nicolae, D. L. et al. Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS. PLoS Genet. 6, e1000888 (2010).
-
(2010)
PLoS Genet.
, vol.6
, pp. e1000888
-
-
Nicolae, D.L.1
|