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Volumn 8, Issue 1, 2018, Pages

Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; ANTIINFECTIVE AGENT; CLOSANTEL; NICLOSAMIDE; OMEPRAZOLE; OXYCLOZANIDE; PANTOPRAZOLE; PROTON PUMP INHIBITOR; RAFOXANIDE; SALICYLANILIDE DERIVATIVE;

EID: 85042719501     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-018-22037-x     Document Type: Article
Times cited : (70)

References (68)
  • 1
    • 84954362099 scopus 로고    scopus 로고
    • The global emergence of Helicobacter pylori antibiotic resistance
    • Thung, I. et al. The global emergence of Helicobacter pylori antibiotic resistance. Alimentary pharmacology & therapeutics 43, 514-533 (2016).
    • (2016) Alimentary Pharmacology & Therapeutics , vol.43 , pp. 514-533
    • Thung, I.1
  • 2
    • 84902084714 scopus 로고    scopus 로고
    • Helicobacter pylori infection: New pathogenetic and clinical aspects
    • Hagymási, K. & Tulassay, Z. Helicobacter pylori infection: new pathogenetic and clinical aspects. World journal of gastroenterology: WJG 20, 6386 (2014).
    • (2014) World Journal of Gastroenterology: WJG , vol.20 , pp. 6386
    • Hagymási, K.1    Tulassay, Z.2
  • 3
    • 84925358100 scopus 로고    scopus 로고
    • Helicobacter pylori update: Gastric cancer, reliable therapy, and possible benefits
    • e713
    • Graham, D. Y. Helicobacter pylori update: gastric cancer, reliable therapy, and possible benefits. Gastroenterology 148, 719-731. e713 (2015).
    • (2015) Gastroenterology , vol.148 , pp. 719-731
    • Graham, D.Y.1
  • 4
    • 77955767264 scopus 로고    scopus 로고
    • Helicobacter pylori infection concomitant with metabolic syndrome further increase risk of colorectal adenomas
    • Lin, Y.-L., Chiang, J.-K., Lin, S.-M. & Tseng, C.-E. Helicobacter pylori infection concomitant with metabolic syndrome further increase risk of colorectal adenomas. World Journal of Gastroenterology: WJG 16, 3841 (2010).
    • (2010) World Journal of Gastroenterology: WJG , vol.16 , pp. 3841
    • Lin, Y.-L.1    Chiang, J.-K.2    Lin, S.-M.3    Tseng, C.-E.4
  • 5
    • 84880802107 scopus 로고    scopus 로고
    • Association between helicobacter pylori infection and the risk of colorectal neoplasia: A systematic review and meta-analysis
    • Wu, Q., Yang, Z. P., Xu, P., Gao, L. C. & Fan, D. M. Association between helicobacter pylori infection and the risk of colorectal neoplasia: a systematic review and meta-analysis. Colorectal Disease 15 (2013).
    • (2013) Colorectal Disease , vol.15
    • Wu, Q.1    Yang, Z.P.2    Xu, P.3    Gao, L.C.4    Fan, D.M.5
  • 6
    • 60749109342 scopus 로고    scopus 로고
    • Acquisition of Helicobacter pylori infection in early childhood: Independent contributions of infected mothers, fathers, and siblings
    • Weyermann, M., Rothenbacher, D. & Brenner, H. Acquisition of Helicobacter pylori infection in early childhood: independent contributions of infected mothers, fathers, and siblings. The American journal of gastroenterology 104, 182 (2009).
    • (2009) The American Journal of Gastroenterology , vol.104 , pp. 182
    • Weyermann, M.1    Rothenbacher, D.2    Brenner, H.3
  • 7
    • 0033194725 scopus 로고    scopus 로고
    • Host determinants of Helicobacter pylori infection and its clinical outcome
    • Nguyen, T. N., Barkun, A. N. & Fallone, C. A. Host determinants of Helicobacter pylori infection and its clinical outcome. Helicobacter 4, 185-197 (1999).
    • (1999) Helicobacter , vol.4 , pp. 185-197
    • Nguyen, T.N.1    Barkun, A.N.2    Fallone, C.A.3
  • 8
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nature reviews
    • Peek, R. M. Jr. & Blaser, M. J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nature reviews. Cancer 2, 28 (2002).
    • (2002) Cancer , vol.2 , pp. 28
    • Peek, R.M.1    Blaser, M.J.2
  • 9
    • 84906764012 scopus 로고    scopus 로고
    • Epidemiology of Helicobacter pylori infection
    • Eusebi, L. H., Zagari, R. M. & Bazzoli, F. Epidemiology of Helicobacter pylori infection. Helicobacter 19, 1-5 (2014).
    • (2014) Helicobacter , vol.19 , pp. 1-5
    • Eusebi, L.H.1    Zagari, R.M.2    Bazzoli, F.3
  • 10
    • 25144466064 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori: A clinical update
    • Romano, M. & Cuomo, A. Eradication of Helicobacter pylori: a clinical update. Medscape General Medicine 6, 19 (2004).
    • (2004) Medscape General Medicine , vol.6 , pp. 19
    • Romano, M.1    Cuomo, A.2
  • 12
    • 84892143010 scopus 로고    scopus 로고
    • Methicillin-resistant Staphylococcus aureus therapy: Past, present, and future
    • Rodvold, K. A. & McConeghy, K. W. Methicillin-resistant Staphylococcus aureus therapy: past, present, and future. Clinical infectious diseases 58, S20-S27 (2014).
    • (2014) Clinical Infectious Diseases , vol.58 , pp. S20-S27
    • Rodvold, K.A.1    McConeghy, K.W.2
  • 13
    • 84928797276 scopus 로고    scopus 로고
    • Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus
    • Rajamuthiah, R. et al. Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus. PLoS One 10, e0124595, https://doi.org/10.1371/journal.pone.0124595 (2015).
    • (2015) PLoS One , vol.10 , pp. e0124595
    • Rajamuthiah, R.1
  • 14
    • 84896751347 scopus 로고    scopus 로고
    • Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus
    • Rajamuthiah, R. et al. Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus. PLoS One 9, e89189, https://doi.org/10.1371/journal.pone.0089189 (2014).
    • (2014) PLoS One , vol.9 , pp. e89189
    • Rajamuthiah, R.1
  • 15
    • 84988036996 scopus 로고    scopus 로고
    • Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile
    • Gooyit, M. & Janda, K. D. Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile. Scientific reports 6, 33642 (2016).
    • (2016) Scientific Reports , vol.6 , pp. 33642
    • Gooyit, M.1    Janda, K.D.2
  • 16
    • 84872874295 scopus 로고    scopus 로고
    • New life for an old drug: The anthelmintic drug niclosamide inhibits Pseudomonas aeruginosa quorum sensing
    • Imperi, F. et al. New life for an old drug: the anthelmintic drug niclosamide inhibits Pseudomonas aeruginosa quorum sensing. Antimicrobial agents and chemotherapy 57, 996-1005 (2013).
    • (2013) Antimicrobial Agents and Chemotherapy , vol.57 , pp. 996-1005
    • Imperi, F.1
  • 17
    • 0032150389 scopus 로고    scopus 로고
    • Anthelmintics: Drugs for treating worms
    • Hall, A. Anthelmintics: drugs for treating worms. Africa health 20, 4-6 (1998).
    • (1998) Africa Health , vol.20 , pp. 4-6
    • Hall, A.1
  • 21
    • 85028338965 scopus 로고    scopus 로고
    • Characterization of a francisella tularensis-caenorhabditis elegans pathosystem for the evaluation of therapeutic compounds
    • Jayamani, E. et al. Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds. Antimicrobial agents and chemotherapy 61, e00310-00317 (2017).
    • (2017) Antimicrobial Agents and Chemotherapy , vol.61 , pp. e00310-00317
    • Jayamani, E.1
  • 22
    • 84866378228 scopus 로고    scopus 로고
    • Mechanisms of Helicobacter pylori antibiotic resistance: An updated appraisal
    • De Francesco, V. et al. Mechanisms of Helicobacter pylori antibiotic resistance: An updated appraisal. World journal of gastrointestinal pathophysiology 2, 35 (2011).
    • (2011) World Journal of Gastrointestinal Pathophysiology , vol.2 , pp. 35
    • De Francesco, V.1
  • 23
    • 77955480115 scopus 로고    scopus 로고
    • Optimal drug synergy in antimicrobial treatments
    • Torella, J. P., Chait, R. & Kishony, R. Optimal drug synergy in antimicrobial treatments. PLoS Comput Biol 6, e1000796 (2010).
    • (2010) PLoS Comput Biol , vol.6 , pp. e1000796
    • Torella, J.P.1    Chait, R.2    Kishony, R.3
  • 25
    • 0037326432 scopus 로고    scopus 로고
    • Antimicrobial activity of esomeprazole versus omeprazole against Helicobacter pylori
    • Gatta, L. et al. Antimicrobial activity of esomeprazole versus omeprazole against Helicobacter pylori. Journal of Antimicrobial Chemotherapy 51, 439-442 (2003).
    • (2003) Journal of Antimicrobial Chemotherapy , vol.51 , pp. 439-442
    • Gatta, L.1
  • 26
    • 0033257538 scopus 로고    scopus 로고
    • Pantoprazole suppresses Helicobacter pylori without affecting cure
    • Adamek, R. J., Szymanski, C. & Pfaffenbach, B. Pantoprazole suppresses Helicobacter pylori without affecting cure. Helicobacter 4, 266-271 (1999).
    • (1999) Helicobacter , vol.4 , pp. 266-271
    • Adamek, R.J.1    Szymanski, C.2    Pfaffenbach, B.3
  • 28
    • 26944496132 scopus 로고    scopus 로고
    • Adherence properties of Helicobacter pylori: Impact on pathogenesis and adaptation to the host
    • Odenbreit, S. Adherence properties of Helicobacter pylori: impact on pathogenesis and adaptation to the host. International journal of medical microbiology 295, 317-324 (2005).
    • (2005) International Journal of Medical Microbiology , vol.295 , pp. 317-324
    • Odenbreit, S.1
  • 29
    • 34047250343 scopus 로고    scopus 로고
    • Helicobacter pylori is invasive and it may be a facultative intracellular organism
    • Dubois, A. & Borén, T. Helicobacter pylori is invasive and it may be a facultative intracellular organism. Cellular microbiology 9, 1108-1116 (2007).
    • (2007) Cellular Microbiology , vol.9 , pp. 1108-1116
    • Dubois, A.1    Borén, T.2
  • 30
    • 67249098317 scopus 로고    scopus 로고
    • Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche
    • Tan, S., Tompkins, L. S. & Amieva, M. R. Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche. PLoS pathogens 5, e1000407 (2009).
    • (2009) PLoS Pathogens , vol.5 , pp. e1000407
    • Tan, S.1    Tompkins, L.S.2    Amieva, M.R.3
  • 31
    • 0031966460 scopus 로고    scopus 로고
    • Omeprazole may exert both a bacteriostatic and a bacteriocidal effect on the growth of Helicobacter pylori (NCTC 11637) in vitro by inhibiting bacterial urease activity
    • Mirshahi, F., Fowler, G., Patel, A. & Shaw, G. Omeprazole may exert both a bacteriostatic and a bacteriocidal effect on the growth of Helicobacter pylori (NCTC 11637) in vitro by inhibiting bacterial urease activity. Journal of clinical pathology 51, 220-224 (1998).
    • (1998) Journal of Clinical Pathology , vol.51 , pp. 220-224
    • Mirshahi, F.1    Fowler, G.2    Patel, A.3    Shaw, G.4
  • 32
    • 9844229885 scopus 로고    scopus 로고
    • Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains
    • Yamaoka, Y. et al. Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains. Gut 41, 442-451 (1997).
    • (1997) Gut , vol.41 , pp. 442-451
    • Yamaoka, Y.1
  • 33
    • 0031015599 scopus 로고    scopus 로고
    • Association of antral mucosal levels of interleukin 8 and reactive oxygen radicals in patients infected with Helicobacter pylori
    • Zhang, Q. et al. Association of antral mucosal levels of interleukin 8 and reactive oxygen radicals in patients infected with Helicobacter pylori. Clinical Science 92, 69-73 (1997).
    • (1997) Clinical Science , vol.92 , pp. 69-73
    • Zhang, Q.1
  • 34
  • 35
    • 85019086270 scopus 로고    scopus 로고
    • Erythromycin modification that improves its acidic stability while optimizing it for local drug delivery
    • Cyphert, E. L., Wallat, J. D., Pokorski, J. K. & von Recum, H. A. Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery. Antibiotics 6, 11 (2017).
    • (2017) Antibiotics , vol.6 , pp. 11
    • Cyphert, E.L.1    Wallat, J.D.2    Pokorski, J.K.3    Von Recum, H.A.4
  • 36
    • 85042688129 scopus 로고    scopus 로고
    • (Wb Saunders Co Independence Square West Curtis Center, Ste 300, Philadelphia, Pa 19106-3399)
    • Daarmaillac, V., Bouchard, S., Lamouliatte, H. & Mégraud, F. In Gastroenterology. A78-A78 (Wb Saunders Co Independence Square West Curtis Center, Ste 300, Philadelphia, Pa 19106-3399).
    • Gastroenterology , pp. A78-A78
    • Daarmaillac, V.1    Bouchard, S.2    Lamouliatte, H.3    Mégraud, F.4
  • 37
    • 33947507582 scopus 로고    scopus 로고
    • Combined effect of pH and concentration on the activities of gentamicin and oxacillin against Staphylococcus aureus in pharmacodynamic models of extracellular and intracellular infections
    • Baudoux, P. et al. Combined effect of pH and concentration on the activities of gentamicin and oxacillin against Staphylococcus aureus in pharmacodynamic models of extracellular and intracellular infections. J Antimicrob Chemother 59, 246-253, https://doi.org/10.1093/jac/dkl489 (2007).
    • (2007) J Antimicrob Chemother , vol.59 , pp. 246-253
    • Baudoux, P.1
  • 38
    • 0030824392 scopus 로고    scopus 로고
    • Effect of pH on in vitro antimicrobial susceptibility of the Bacteroides fragilis group
    • Falagas, M. E., McDermott, L. & Snydman, D. R. Effect of pH on in vitro antimicrobial susceptibility of the Bacteroides fragilis group. Antimicrob Agents Chemother 41, 2047-2049 (1997).
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2047-2049
    • Falagas, M.E.1    McDermott, L.2    Snydman, D.R.3
  • 39
    • 34248367724 scopus 로고    scopus 로고
    • Role of acidic pH in the susceptibility of intraphagocytic methicillin-resistant Staphylococcus aureus strains to meropenem and cloxacillin
    • Lemaire, S., Van Bambeke, F., Mingeot-Leclercq, M. P., Glupczynski, Y. & Tulkens, P. M. Role of acidic pH in the susceptibility of intraphagocytic methicillin-resistant Staphylococcus aureus strains to meropenem and cloxacillin. Antimicrob Agents Chemother 51, 1627-1632, https://doi.org/10.1128/AAC.01192-06 (2007).
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 1627-1632
    • Lemaire, S.1    Van Bambeke, F.2    Mingeot-Leclercq, M.P.3    Glupczynski, Y.4    Tulkens, P.M.5
  • 40
    • 84964877024 scopus 로고    scopus 로고
    • Prevalence of antibiotic resistance in Helicobacter pylori: A recent literature review
    • Ghotaslou, R., Leylabadlo, H. E. & Asl, Y. M. Prevalence of antibiotic resistance in Helicobacter pylori: A recent literature review. World journal of methodology 5, 164 (2015).
    • (2015) World Journal of Methodology , vol.5 , pp. 164
    • Ghotaslou, R.1    Leylabadlo, H.E.2    Asl, Y.M.3
  • 41
    • 84988708761 scopus 로고    scopus 로고
    • Helicobacter pylori eradication with proton pump inhibitors or potassium-competitive acid blockers: The effect of clarithromycin resistance
    • Matsumoto, H. et al. Helicobacter pylori eradication with proton pump inhibitors or potassium-competitive acid blockers: the effect of clarithromycin resistance. Digestive diseases and sciences 61, 3215-3220 (2016).
    • (2016) Digestive Diseases and Sciences , vol.61 , pp. 3215-3220
    • Matsumoto, H.1
  • 42
    • 0036128606 scopus 로고    scopus 로고
    • Helicobacter pylori uses motility for initial colonization and to attain robust infection
    • Ottemann, K. M. & Lowenthal, A. C. Helicobacter pylori uses motility for initial colonization and to attain robust infection. Infection and immunity 70, 1984-1990 (2002).
    • (2002) Infection and Immunity , vol.70 , pp. 1984-1990
    • Ottemann, K.M.1    Lowenthal, A.C.2
  • 43
    • 84958582334 scopus 로고    scopus 로고
    • Critical role of antimicrobial peptide cathelicidin for controlling helicobacter pylori survival and infection
    • Zhang, L. et al. Critical role of antimicrobial peptide cathelicidin for controlling helicobacter pylori survival and infection. The Journal of Immunology 196, 1799-1809 (2016).
    • (2016) The Journal of Immunology , vol.196 , pp. 1799-1809
    • Zhang, L.1
  • 44
    • 79251485942 scopus 로고    scopus 로고
    • Targeting of Helicobacter pylori VacA to mitochondria
    • Galmiche, A. & Rassow, J. Targeting of Helicobacter pylori VacA to mitochondria. Gut microbes 1, 392-395 (2010).
    • (2010) Gut Microbes , vol.1 , pp. 392-395
    • Galmiche, A.1    Rassow, J.2
  • 45
    • 0032563331 scopus 로고    scopus 로고
    • Vacuolation induced by cytotoxin from Helicobacter pylori is mediated by the EGF receptor in HeLa cells
    • Seto, K., Hayashi-Kuwabara, Y., Yoneta, T., Suda, H. & Tamaki, H. Vacuolation induced by cytotoxin from Helicobacter pylori is mediated by the EGF receptor in HeLa cells. FEBS letters 431, 347-350 (1998).
    • (1998) FEBS Letters , vol.431 , pp. 347-350
    • Seto, K.1    Hayashi-Kuwabara, Y.2    Yoneta, T.3    Suda, H.4    Tamaki, H.5
  • 46
    • 78650293305 scopus 로고    scopus 로고
    • Targeting bacterial membrane function: An underexploited mechanism for treating persistent infections
    • Hurdle, J. G., O'neill, A. J., Chopra, I. & Lee, R. E. Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections. Nature Reviews Microbiology 9, 62-75 (2011).
    • (2011) Nature Reviews Microbiology , vol.9 , pp. 62-75
    • Hurdle, J.G.1    O'Neill, A.J.2    Chopra, I.3    Lee, R.E.4
  • 47
    • 84984601509 scopus 로고    scopus 로고
    • Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions
    • Zhao, J., He, Q., Gong, Z., Chen, S. & Cui, L. Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions. Springer Plus 5, 1436 (2016).
    • (2016) Springer Plus , vol.5 , pp. 1436
    • Zhao, J.1    He, Q.2    Gong, Z.3    Chen, S.4    Cui, L.5
  • 48
    • 84884512993 scopus 로고    scopus 로고
    • Collapsing the proton motive force to identify synergistic combinations against Staphylococcus aureus
    • Farha, M. A., Verschoor, C. P., Bowdish, D. & Brown, E. D. Collapsing the proton motive force to identify synergistic combinations against Staphylococcus aureus. Chemistry & biology 20, 1168-1178 (2013).
    • (2013) Chemistry & Biology , vol.20 , pp. 1168-1178
    • Farha, M.A.1    Verschoor, C.P.2    Bowdish, D.3    Brown, E.D.4
  • 49
    • 85027245424 scopus 로고    scopus 로고
    • Activity of a novel protonophore against methicillin-resistant Staphylococcus aureus
    • In press
    • Tharmalingam, N. et al. Activity of a novel protonophore against methicillin-resistant Staphylococcus aureus. Future Med Chem In press (2017).
    • (2017) Future Med Chem
    • Tharmalingam, N.1
  • 51
    • 84895648029 scopus 로고    scopus 로고
    • U. S. Niclosamide EPA
    • Prevention, U. S. Niclosamide EPA (1999).
    • (1999) Prevention
  • 52
    • 84906929990 scopus 로고    scopus 로고
    • Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori
    • Giannouli, M. et al. Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori. BMC microbiology 14, 228 (2014).
    • (2014) BMC Microbiology , vol.14 , pp. 228
    • Giannouli, M.1
  • 54
    • 85042733033 scopus 로고    scopus 로고
    • Antibacterial properties of four novel hit compounds from a methicillin-resistant staphylococcus aureus-caenorhabditis elegans high-throughput screen
    • (Accepted)
    • Tharmalingam, N. et al. Antibacterial Properties of Four Novel Hit Compounds from a Methicillin-Resistant Staphylococcus aureus-Caenorhabditis elegans High-Throughput Screen Microbial Drug Resistance (Accepted) (2018).
    • (2018) Microbial Drug Resistance
    • Tharmalingam, N.1
  • 55
    • 85029150047 scopus 로고    scopus 로고
    • Repurposing niclosamide as a versatile antimicrobial surface coating against device-associated, hospital-acquired bacterial infections
    • Gwisai, T. et al. Repurposing niclosamide as a versatile antimicrobial surface coating against device-associated, hospital-acquired bacterial infections. Biomedical Materials (2017).
    • (2017) Biomedical Materials
    • Gwisai, T.1
  • 56
    • 85021913413 scopus 로고    scopus 로고
    • Synergistic efficacy of Aedes aegypti antimicrobial peptide cecropin A2 and tetracycline against Pseudomonas aeruginosa
    • Zheng, Z. et al. Synergistic efficacy of Aedes aegypti antimicrobial peptide cecropin A2 and tetracycline against Pseudomonas aeruginosa. Antimicrob Agents Chemother 61 (2017).
    • (2017) Antimicrob Agents Chemother , vol.61
    • Zheng, Z.1
  • 57
    • 84897918849 scopus 로고    scopus 로고
    • The use of resazurin as a novel antimicrobial agent against Francisella tularensis
    • Schmitt, D. M. et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis. Front Cell Infect Microbiol 3, 93, https://doi.org/10.3389/fcimb.2013.00093 (2013).
    • (2013) Front Cell Infect Microbiol , vol.3 , pp. 93
    • Schmitt, D.M.1
  • 58
    • 84962069179 scopus 로고    scopus 로고
    • Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes β-catenin mediated oncogenesis and IL-8 secretion in vitro
    • Tharmalingam, N. et al. Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes β-catenin mediated oncogenesis and IL-8 secretion in vitro. American journal of translational research 8, 885 (2016).
    • (2016) American Journal of Translational Research , vol.8 , pp. 885
    • Tharmalingam, N.1
  • 59
    • 85007575573 scopus 로고    scopus 로고
    • Menadione induces G2/M arrest in gastric cancer cells by down-regulation of CDC25C and proteasome mediated degradation of CDK1 and cyclin B1
    • Lee, M. H. et al. Menadione induces G2/M arrest in gastric cancer cells by down-regulation of CDC25C and proteasome mediated degradation of CDK1 and cyclin B1. American journal of translational research 8, 5246 (2016).
    • (2016) American Journal of Translational Research , vol.8 , pp. 5246
    • Lee, M.H.1
  • 60
    • 0028824813 scopus 로고
    • The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure
    • De Kimpe, S. J., Kengatharan, M., Thiemermann, C. & Vane, J. R. The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. Proceedings of the National Academy of Sciences 92, 10359-10363 (1995).
    • (1995) Proceedings of the National Academy of Sciences , vol.92 , pp. 10359-10363
    • De Kimpe, S.J.1    Kengatharan, M.2    Thiemermann, C.3    Vane, J.R.4
  • 61
    • 85042698437 scopus 로고    scopus 로고
    • Antimicrobial activity of 1,3,4-oxadiazole derivatives against planktonic cells and biofilm of Staphylococcus aureus
    • Accepted
    • Zheng, Z. et al. Antimicrobial activity of 1,3,4-oxadiazole derivatives against planktonic cells and biofilm of Staphylococcus aureus. Future Medicinal Chemistry Accepted (2017).
    • (2017) Future Medicinal Chemistry
    • Zheng, Z.1
  • 62
    • 0035867057 scopus 로고    scopus 로고
    • Comparative in vitro and in vivo activity of the C-8 methoxy quinolone moxifloxacin and the C-8 chlorine quinolone BAY y 3118
    • Dalhoff, A. Comparative in vitro and in vivo activity of the C-8 methoxy quinolone moxifloxacin and the C-8 chlorine quinolone BAY y 3118. Clinical infectious diseases 32, S16-S22 (2001).
    • (2001) Clinical Infectious Diseases , vol.32 , pp. S16-S22
    • Dalhoff, A.1
  • 63
    • 0027252455 scopus 로고
    • Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flaB flagellin genes and construction of H. Pylori flaA-and flaB-negative mutants by electroporation-mediated allelic exchange
    • Suerbaum, S., Josenhans, C. & Labigne, A. Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flaB flagellin genes and construction of H. pylori flaA-and flaB-negative mutants by electroporation-mediated allelic exchange. Journal of bacteriology 175, 3278-3288 (1993).
    • (1993) Journal of Bacteriology , vol.175 , pp. 3278-3288
    • Suerbaum, S.1    Josenhans, C.2    Labigne, A.3
  • 64
    • 84946576631 scopus 로고    scopus 로고
    • Inhibitory effect of piperine on Helicobacter pylori growth and adhesion to gastric adenocarcinoma cells
    • Tharmalingam, N. et al. Inhibitory effect of piperine on Helicobacter pylori growth and adhesion to gastric adenocarcinoma cells. Infectious agents and cancer 9, 43 (2014).
    • (2014) Infectious Agents and Cancer , vol.9 , pp. 43
    • Tharmalingam, N.1
  • 65
    • 84932629790 scopus 로고    scopus 로고
    • Identification of an antimicrobial agent effective against methicillin-resistant staphylococcus aureus persisters using a fluorescence-based screening strategy
    • Kim, W. et al. Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy. PLoS One 10, e0127640, https://doi.org/10.1371/journal.pone.0127640 (2015).
    • (2015) PLoS One , vol.10 , pp. e0127640
    • Kim, W.1
  • 66
    • 0033958917 scopus 로고    scopus 로고
    • Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease
    • Scott, D. R. et al. Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease. Infection and immunity 68, 470-477 (2000).
    • (2000) Infection and Immunity , vol.68 , pp. 470-477
    • Scott, D.R.1
  • 67
    • 84902962360 scopus 로고    scopus 로고
    • Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis
    • Kwon, B. et al. Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis. Hum Mol Genet 23, 3681-3694, https://doi.org/10.1093/hmg/ddu077 (2014).
    • (2014) Hum Mol Genet , vol.23 , pp. 3681-3694
    • Kwon, B.1
  • 68
    • 0037308523 scopus 로고    scopus 로고
    • MC21-A, a bactericidal antibiotic produced by a new marine bacterium, Pseudoalteromonas phenolica sp. Nov. O-BC30(T), against methicillin-resistant Staphylococcus aureus
    • Isnansetyo, A. & Kamei, Y. MC21-A, a bactericidal antibiotic produced by a new marine bacterium, Pseudoalteromonas phenolica sp. nov. O-BC30(T), against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 47, 480-488 (2003).
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 480-488
    • Isnansetyo, A.1    Kamei, Y.2


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