Identification of an antimicrobial agent effective against methicillin-resistant Staphylococcus aureus persisters using a fluorescence-based screening strategy

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Kim, Wooseong ^a   Conery, Annie L ^b   Rajamuthiah, Rajmohan ^a,b   Fuchs, Beth Burgwyn ^a,b   Ausubel, Frederick M ^b   Mylonakis, Eleftherios ^a  

^a BROWN UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CIPROFLOXACIN; GENTAMICIN; NH 125; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; ORGANIC COMPOUND; SYTOX GREEN;

ARTICLE; BACTERIAL STRAIN; BACTERIAL VIABILITY; BACTERIUM ISOLATION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFECT; DRUG IDENTIFICATION; DRUG SCREENING; FLUORESCENCE ANALYSIS; LIMIT OF DETECTION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ANIMAL; BIOFILM; CAENORHABDITIS ELEGANS; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE; MICROBIOLOGY; PHYSIOLOGY; PRECLINICAL STUDY; STAPHYLOCOCCAL INFECTIONS;

BACTERIA (MICROORGANISMS); CAENORHABDITIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CAENORHABDITIS ELEGANS; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; ORGANIC CHEMICALS; STAPHYLOCOCCAL INFECTIONS;

EID: 84932629790     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127640     Document Type: Article

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