New life for an old Drug: The anthelmintic drug niclosamide inhibits pseudomonas aeruginosa quorum sensing

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 2, 2013, Pages 996-1005

  Imperi, Francesco ^a   Massai, Francesco ^a   Pillai, Cejoice Ramachandran ^a   Longo, Francesca ^b   Zennaro, Elisabetta ^b   Rampioni, Giordano ^b   Visc, Paolo ^a,b   Leoni, Livia ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; N ACYLHOMOSERINE LACTONE; NICLOSAMIDE; PYOCYANINE; RHAMNOLIPID; TRANSCRIPTOME;

AGAR GEL ELECTROPHORESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL VIRULENCE; BIOFILM; BIOSENSOR; CELL DENSITY; CONTROLLED STUDY; GALLERIA MELLONELLA; GENE CONTROL; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; NONHUMAN; PATHOGENICITY; PHENOTYPE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; QUORUM SENSING;

ACYL-BUTYROLACTONES; ANTI-BACTERIAL AGENTS; ANTICESTODAL AGENTS; ANTINEMATODAL AGENTS; BIOFILMS; DRUG DISCOVERY; GLYCOLIPIDS; NICLOSAMIDE; PANCREATIC ELASTASE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; PYOCYANINE; QUORUM SENSING; VIRULENCE FACTORS;

EID: 84872874295     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01952-12     Document Type: Article

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