-
1
-
-
84954093852
-
Molecular pathways: targeting IDO1 and Other tryptophan dioxygenases for cancer immunotherapy
-
Zhai L, Spranger S, Binder DC, Gritsina G, Lauing KL, Giles FJ, et al. Molecular pathways: targeting IDO1 and Other tryptophan dioxygenases for cancer immunotherapy. Clin Cancer Res (2015) 21:5427-33. doi:10.1158/1078-0432.CCR-15-0420
-
(2015)
Clin Cancer Res
, vol.21
, pp. 5427-5433
-
-
Zhai, L.1
Spranger, S.2
Binder, D.C.3
Gritsina, G.4
Lauing, K.L.5
Giles, F.J.6
-
2
-
-
85041630102
-
Indoleamine 2,3-dioxygenase (IDO): only an enzyme or a checkpoint controller?
-
Bilir C, Sarisozen C. Indoleamine 2,3-dioxygenase (IDO): only an enzyme or a checkpoint controller?. J Oncol Sci (2017) 3:52-6. doi:10.1016/j.jons.2017.04.001
-
(2017)
J Oncol Sci
, vol.3
, pp. 52-56
-
-
Bilir, C.1
Sarisozen, C.2
-
3
-
-
85016108719
-
A database of transcription factor binding sites identified by ChIP-seq experiments
-
Yevshin I, Sharipov R, Valeev T, Kel A, Kolpakov FGTRD. A database of transcription factor binding sites identified by ChIP-seq experiments. Nucleic Acids Res (2017) 45:D61-7. doi:10.1093/nar/gkw951
-
(2017)
Nucleic Acids Res
, vol.45
, pp. D61-D67
-
-
Yevshin, I.1
Sharipov, R.2
Valeev, T.3
Kel, A.4
Kolpakov, F.G.T.R.D.5
-
4
-
-
84926652188
-
Tryptophan-degrading enzymes in tumoral immune resistance
-
van Baren N, Van den Eynde BJ. Tryptophan-degrading enzymes in tumoral immune resistance. Front Immunol (2015) 6:34. doi:10.3389/fimmu.2015.00034
-
(2015)
Front Immunol
, vol.6
, pp. 34
-
-
van Baren, N.1
Van den Eynde, B.J.2
-
5
-
-
85019201137
-
A subcellular map of the human proteome
-
Thul PJ, Akesson L, Wiking M, Mahdessian D, Geladaki A, Ait Blal H, et al. A subcellular map of the human proteome. Science (2017) 356:eaal3321. doi:10.1126/science.aal3321
-
(2017)
Science
, vol.356
-
-
Thul, P.J.1
Akesson, L.2
Wiking, M.3
Mahdessian, D.4
Geladaki, A.5
Ait Blal, H.6
-
6
-
-
85010900146
-
Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors
-
Zulfiqar B, Mahroo A, Nasir K, Farooq RK, Jalal N, Rashid MU, et al. Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors. Onco Targets Ther (2017) 10:463-76. doi:10.2147/OTT.S119362
-
(2017)
Onco Targets Ther
, vol.10
, pp. 463-476
-
-
Zulfiqar, B.1
Mahroo, A.2
Nasir, K.3
Farooq, R.K.4
Jalal, N.5
Rashid, M.U.6
-
7
-
-
84885459070
-
Aryl hydrocarbon receptor signaling regulates NF-κB RelB activation during dendritic-cell differentiation
-
Vogel CFA, Wu D, Goth SR, Baek J, Lollies A, Domhardt R, et al. Aryl hydrocarbon receptor signaling regulates NF-κB RelB activation during dendritic-cell differentiation. Immunol Cell Biol (2013) 91:568-75. doi:10.1038/icb.2013.43
-
(2013)
Immunol Cell Biol
, vol.91
, pp. 568-575
-
-
Vogel, C.F.A.1
Wu, D.2
Goth, S.R.3
Baek, J.4
Lollies, A.5
Domhardt, R.6
-
8
-
-
84918842254
-
AhR-mediated, non-genomic modulation of IDO1 function
-
Pallotta MT, Fallarino F, Matino D, Macchiarulo A, Orabona C. AhR-mediated, non-genomic modulation of IDO1 function. Front Immunol (2014) 5:497. doi:10.3389/fimmu.2014.00497
-
(2014)
Front Immunol
, vol.5
, pp. 497
-
-
Pallotta, M.T.1
Fallarino, F.2
Matino, D.3
Macchiarulo, A.4
Orabona, C.5
-
9
-
-
84923366733
-
Chromatin architecture reorganization during stem cell differentiation
-
Dixon JR, Jung I, Selvaraj S, Shen Y, Antosiewicz-Bourget JE, Lee AY, et al. Chromatin architecture reorganization during stem cell differentiation. Nature (2015) 518:331-6. doi:10.1038/nature14222
-
(2015)
Nature
, vol.518
, pp. 331-336
-
-
Dixon, J.R.1
Jung, I.2
Selvaraj, S.3
Shen, Y.4
Antosiewicz-Bourget, J.E.5
Lee, A.Y.6
-
10
-
-
0028287976
-
Nitric oxide inhibits indoleamine 2, 3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes
-
Thomas SR, Mohr D, Stocker R. Nitric oxide inhibits indoleamine 2, 3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes. J Biol Chem (1994) 269:14457-64.
-
(1994)
J Biol Chem
, vol.269
, pp. 14457-14464
-
-
Thomas, S.R.1
Mohr, D.2
Stocker, R.3
-
11
-
-
34548204420
-
Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide
-
Thomas SR, Terentis AC, Cai H, Takikawa O, Levina A, Lay PA, et al. Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide. J Biol Chem (2007) 282:23778-87. doi:10.1074/jbc. M700669200
-
(2007)
J Biol Chem
, vol.282
, pp. 23778-23787
-
-
Thomas, S.R.1
Terentis, A.C.2
Cai, H.3
Takikawa, O.4
Levina, A.5
Lay, P.A.6
-
12
-
-
2142754480
-
Nitric oxide-mediated regulation of gamma interferon-induced bacteriostasis: inhibition and degradation of human indoleamine 2,3-dioxygenase
-
Hucke C, MacKenzie CR, Adjogble KDZ, Takikawa O, Däubener W. Nitric oxide-mediated regulation of gamma interferon-induced bacteriostasis: inhibition and degradation of human indoleamine 2,3-dioxygenase. Infect Immun (2004) 72:2723-30. doi:10.1128/IAI.72.5.2723-2730.2004
-
(2004)
Infect Immun
, vol.72
, pp. 2723-2730
-
-
Hucke, C.1
MacKenzie, C.R.2
Adjogble, K.D.Z.3
Takikawa, O.4
Däubener, W.5
-
13
-
-
0033592288
-
Inhibition of NF-kB activation by pyrrolidine dithiocarbamate prevents in vivo expression of
-
Genes P, Liu SF, Ye X, Malik AB. Inhibition of NF-kB activation by pyrrolidine dithiocarbamate prevents in vivo expression of. Circulation (1999) 100:1330-7. doi:10.1161/01.CIR.100.12.1330
-
(1999)
Circulation
, vol.100
, pp. 1330-1337
-
-
Genes, P.1
Liu, S.F.2
Ye, X.3
Malik, A.B.4
-
14
-
-
0035873436
-
Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate
-
Thomas SR, Salahifar H, Mashima R, Hunt NH, Richardson DR, Stocker R. Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate. J Immunol (2001) 166:6332-40. doi:10.4049/jimmunol.166.10.6332
-
(2001)
J Immunol
, vol.166
, pp. 6332-6340
-
-
Thomas, S.R.1
Salahifar, H.2
Mashima, R.3
Hunt, N.H.4
Richardson, D.R.5
Stocker, R.6
-
15
-
-
29644441241
-
Nitration and inactivation of IDO by peroxynitrite
-
Fujigaki H, Saito K, Lin F, Fujigaki S, Takahashi K, Martin BM, et al. Nitration and inactivation of IDO by peroxynitrite. J Immunol (2006) 176:372-9. doi:10.4049/jimmunol.176.1.372
-
(2006)
J Immunol
, vol.176
, pp. 372-379
-
-
Fujigaki, H.1
Saito, K.2
Lin, F.3
Fujigaki, S.4
Takahashi, K.5
Martin, B.M.6
-
16
-
-
0037815119
-
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
-
Grohmann U, Fallarino F, Bianchi R, Orabona C, Vacca C, Fioretti MC, et al. A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. J Exp Med (2003) 198:153-60. doi:10.1084/jem.20030633
-
(2003)
J Exp Med
, vol.198
, pp. 153-160
-
-
Grohmann, U.1
Fallarino, F.2
Bianchi, R.3
Orabona, C.4
Vacca, C.5
Fioretti, M.C.6
-
17
-
-
84877677988
-
Regulation of IDO activity by oxygen supply: inhibitory effects on antimicrobial and immunoregulatory functions
-
Schmidt SK, Ebel S, Keil E, Woite C, Ernst JF, Benzin AE, et al. Regulation of IDO activity by oxygen supply: inhibitory effects on antimicrobial and immunoregulatory functions. PLoS One (2013) 8:e63301. doi:10.1371/journal.pone.0063301
-
(2013)
PLoS One
, vol.8
-
-
Schmidt, S.K.1
Ebel, S.2
Keil, E.3
Woite, C.4
Ernst, J.F.5
Benzin, A.E.6
-
18
-
-
79551477978
-
Hypoxia regulates the production and activity of glucose transporter-1 and indoleamine 2,3-dioxygenase in monocyte-derived endothelial-like cells: possible relevance to infantile haemangioma pathogenesis
-
Herbert A, Ng H, Jessup W, Kockx M, Cartland S, Thomas SR, et al. Hypoxia regulates the production and activity of glucose transporter-1 and indoleamine 2,3-dioxygenase in monocyte-derived endothelial-like cells: possible relevance to infantile haemangioma pathogenesis. Br J Dermatol (2011) 164:308-15. doi:10.1111/j.1365-2133.2010.10086.x
-
(2011)
Br J Dermatol
, vol.164
, pp. 308-315
-
-
Herbert, A.1
Ng, H.2
Jessup, W.3
Kockx, M.4
Cartland, S.5
Thomas, S.R.6
-
19
-
-
73949087467
-
T-cell activation under hypoxic conditions enhances IFN-γ secretion
-
Roman J, Rangasamy T, Guo J, Sugunan S, Meednu N, Packirisamy G, et al. T-cell activation under hypoxic conditions enhances IFN-γ secretion. Am J Respir Cell Mol Biol (2010) 42:123-8. doi:10.1165/rcmb.2008-0139OC
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 123-128
-
-
Roman, J.1
Rangasamy, T.2
Guo, J.3
Sugunan, S.4
Meednu, N.5
Packirisamy, G.6
-
20
-
-
58549107152
-
SOCS3 drives proteasomal degradation of indoleamine 2, 3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis
-
Orabona C, Pallotta MT, Volpi C, Fallarino F, Vacca C, Bianchi R, et al. SOCS3 drives proteasomal degradation of indoleamine 2, 3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis. Proc Natl Acad Sci U S A (2008) 105:20828-33. doi:10.1073/pnas.0810278105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20828-20833
-
-
Orabona, C.1
Pallotta, M.T.2
Volpi, C.3
Fallarino, F.4
Vacca, C.5
Bianchi, R.6
-
21
-
-
84859827337
-
Proteasomal degradation of indoleamine 2,3-dioxygenase in CD8+ dendritic cells is mediated by suppressor of cytokine signaling 3 (SOCS3)
-
Maria P, CIriana O, Claudia V, Ursula G, Paolo P, Francesca F. Proteasomal degradation of indoleamine 2,3-dioxygenase in CD8+ dendritic cells is mediated by suppressor of cytokine signaling 3 (SOCS3). Int J Tryptophan Res (2010) 3:91-7. doi:10.4137/IJTR.S3971
-
(2010)
Int J Tryptophan Res
, vol.3
, pp. 91-97
-
-
Maria, P.1
Iriana, O.C.2
Claudia, V.3
Ursula, G.4
Paolo, P.5
Francesca, F.6
-
22
-
-
84990184780
-
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1
-
Albini E, Rosini V, Gargaro M, Mondanelli G, Belladonna ML, Pallotta MT, et al. Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. J Cell Mol Med (2017) 21:165-76. doi:10.1111/jcmm.12954
-
(2017)
J Cell Mol Med
, vol.21
, pp. 165-176
-
-
Albini, E.1
Rosini, V.2
Gargaro, M.3
Mondanelli, G.4
Belladonna, M.L.5
Pallotta, M.T.6
-
23
-
-
84870476787
-
Different partners, opposite outcomes: a new perspective of the immunobiology of indoleamine 2,3-dioxygenase
-
Orabona C, Pallotta M, Grohmann U. Different partners, opposite outcomes: a new perspective of the immunobiology of indoleamine 2,3-dioxygenase. Mol Med (2012) 18:834-42. doi:10.2119/molmed.2012.00029
-
(2012)
Mol Med
, vol.18
, pp. 834-842
-
-
Orabona, C.1
Pallotta, M.2
Grohmann, U.3
-
24
-
-
85012926948
-
A relay pathway between arginine and tryptophan metabolism confers immunosuppressive properties on dendritic cells
-
Mondanelli G, Bianchi R, Pallotta MT, Orabona C, Albini E, Iacono A, et al. A relay pathway between arginine and tryptophan metabolism confers immunosuppressive properties on dendritic cells. Immunity (2017) 46:233-44. doi:10.1016/j.immuni.2017.01.005
-
(2017)
Immunity
, vol.46
, pp. 233-244
-
-
Mondanelli, G.1
Bianchi, R.2
Pallotta, M.T.3
Orabona, C.4
Albini, E.5
Iacono, A.6
-
25
-
-
84904216760
-
Aryl hydrocarbon receptor control of a disease tolerance defense pathway
-
Bessede A, Gargaro M, Pallotta MT, Matino D, Brunacci C, Bicciato S, et al. Aryl hydrocarbon receptor control of a disease tolerance defense pathway. Nature (2015) 511:184-90. doi:10.1038/nature13323.Aryl
-
(2015)
Nature
, vol.511
, pp. 184-190
-
-
Bessede, A.1
Gargaro, M.2
Pallotta, M.T.3
Matino, D.4
Brunacci, C.5
Bicciato, S.6
-
26
-
-
84875261622
-
Indoleamine 2,3 dioxygenase and metabolic control of immune responses
-
Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol (2013) 34:137-43. doi:10.1016/j.it.2012.10.001
-
(2013)
Trends Immunol
, vol.34
, pp. 137-143
-
-
Munn, D.H.1
Mellor, A.L.2
-
27
-
-
84919712776
-
New insights into IDO biology in bacterial and viral infections
-
Schmidt SV, Schultze JL. New insights into IDO biology in bacterial and viral infections. Front Immunol (2014) 5:384. doi:10.3389/fimmu.2014.00384
-
(2014)
Front Immunol
, vol.5
, pp. 384
-
-
Schmidt, S.V.1
Schultze, J.L.2
-
28
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science (1998) 281:1191-3. doi:10.1126/science.281.5380.1191
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
Bondarev, I.4
Conway, S.J.5
Marshall, B.6
-
29
-
-
84980650089
-
Understanding the role of the kynurenine pathway in human breast cancer immunobiology
-
Heng B, Lim CK, Lovejoy DB, Bessede A, Gluch L, Guillemin GJ. Understanding the role of the kynurenine pathway in human breast cancer immunobiology. Oncotarget (2016) 7:6506-20. doi:10.18632/oncotarget.6467
-
(2016)
Oncotarget
, vol.7
, pp. 6506-6520
-
-
Heng, B.1
Lim, C.K.2
Lovejoy, D.B.3
Bessede, A.4
Gluch, L.5
Guillemin, G.J.6
-
30
-
-
79956004948
-
3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival
-
Zaher SS, Germain C, Fu H, Larkin DFP, George AJT. 3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci (2011) 52:2640-8. doi:10.1167/iovs.10-5793
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 2640-2648
-
-
Zaher, S.S.1
Germain, C.2
Fu, H.3
Larkin, D.F.P.4
George, A.J.T.5
-
31
-
-
84962448887
-
The tryptophan metabolite picolinic acid suppresses proliferation and metabolic activity of CD4+ T cells and inhibits c-Myc activation
-
Prodinger J, Loacker LJ, Schmidt RLJ, Ratzinger F, Greiner G, Witzeneder N, et al. The tryptophan metabolite picolinic acid suppresses proliferation and metabolic activity of CD4+ T cells and inhibits c-Myc activation. J Leukoc Biol (2016) 99:583-94. doi:10.1189/jlb.3A0315-135R
-
(2016)
J Leukoc Biol
, vol.99
, pp. 583-594
-
-
Prodinger, J.1
Loacker, L.J.2
Schmidt, R.L.J.3
Ratzinger, F.4
Greiner, G.5
Witzeneder, N.6
-
32
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann U, Orabona C, Fallarino F, Vacca C, Calcinaro F, Falorni A, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol (2002) 3:1097-101. doi:10.1038/ni846
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
Vacca, C.4
Calcinaro, F.5
Falorni, A.6
-
33
-
-
41149132390
-
Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
-
Katz JB, Muller AJ, Prendergast GC. Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape. Immunol Rev (2008) 222:206-21. doi:10.1111/j.1600-065X.2008.00610.x
-
(2008)
Immunol Rev
, vol.222
, pp. 206-221
-
-
Katz, J.B.1
Muller, A.J.2
Prendergast, G.C.3
-
34
-
-
54849418903
-
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
-
Löb S, Königsrainer A, Zieker D, Brücher BLDM, Rammensee HG, Opelz G, et al. IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism. Cancer Immunol Immunother (2009) 58:153-7. doi:10.1007/s00262-008-0513-6
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 153-157
-
-
Löb, S.1
Königsrainer, A.2
Zieker, D.3
Brücher, B.L.D.M.4
Rammensee, H.G.5
Opelz, G.6
-
35
-
-
81255138408
-
Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives
-
Godin-Ethier J, HanafiL-A, Piccirillo CA, Lapointe R. Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives. Clin Cancer Res (2011) 17:6985-91. doi:10.1158/1078-0432.CCR-11-1331
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6985-6991
-
-
Godin-Ethier, J.1
HanafiL-A.2
Piccirillo, C.A.3
Lapointe, R.4
-
36
-
-
85021185202
-
Cervical cancer neoantigen landscape and immune activity is associated with human papillomavirus master regulators
-
Qin Y, Ekmekcioglu S, Forget M-A, Szekvolgyi L, Hwu P, Grimm EA, et al. Cervical cancer neoantigen landscape and immune activity is associated with human papillomavirus master regulators. Front Immunol (2017) 8:689. doi:10.3389/fimmu.2017.00689
-
(2017)
Front Immunol
, vol.8
, pp. 689
-
-
Qin, Y.1
Ekmekcioglu, S.2
Forget, M-A.3
Szekvolgyi, L.4
Hwu, P.5
Grimm, E.A.6
-
37
-
-
85028853575
-
The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade
-
Foy JP, Bertolus C, Michallet MC, Deneuve S, Incitti R, Bendriss-Vermare N, et al. The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade. Ann Oncol (2017) 28:1934-41. doi:10.1093/annonc/mdx210
-
(2017)
Ann Oncol
, vol.28
, pp. 1934-1941
-
-
Foy, J.P.1
Bertolus, C.2
Michallet, M.C.3
Deneuve, S.4
Incitti, R.5
Bendriss-Vermare, N.6
-
38
-
-
84990857069
-
In vitro cytokine licensing induces persistent permissive chromatin at the Indoleamine 2,3-dioxygenase promoter
-
Rovira Gonzalez YI, Lynch PJ, Thompson EE, Stultz BG, Hursh DA. In vitro cytokine licensing induces persistent permissive chromatin at the Indoleamine 2,3-dioxygenase promoter. Cytotherapy (2016) 18:1114-28. doi:10.1016/j.jcyt.2016.05.017
-
(2016)
Cytotherapy
, vol.18
, pp. 1114-1128
-
-
Rovira Gonzalez, Y.I.1
Lynch, P.J.2
Thompson, E.E.3
Stultz, B.G.4
Hursh, D.A.5
-
39
-
-
84952922317
-
IL-27 induces the expression of IDO and PD-L1 in human cancer cells
-
Carbotti G, Barisione G, Airoldi I, Mezzanzanica D, Bagnoli M, Ferrero S, et al. IL-27 induces the expression of IDO and PD-L1 in human cancer cells. Oncotarget (2015) 6:43267-80. doi:10.18632/oncotarget.6530
-
(2015)
Oncotarget
, vol.6
, pp. 43267-43280
-
-
Carbotti, G.1
Barisione, G.2
Airoldi, I.3
Mezzanzanica, D.4
Bagnoli, M.5
Ferrero, S.6
-
41
-
-
66549102581
-
Co-operative action of interleukin-10 and interferon-γ to regulate dendritic cell functions
-
Yanagawa Y, Iwabuchi K, Onoé K. Co-operative action of interleukin-10 and interferon-γ to regulate dendritic cell functions. Immunology (2009) 127:345-53. doi:10.1111/j.1365-2567.2008.02986.x
-
(2009)
Immunology
, vol.127
, pp. 345-353
-
-
Yanagawa, Y.1
Iwabuchi, K.2
Onoé, K.3
-
42
-
-
52649138296
-
Adenosine receptors in regulation of dendritic cell differentiation and function
-
Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, et al. Adenosine receptors in regulation of dendritic cell differentiation and function. Blood (2008) 112:1822-31. doi:10.1182/blood-2008-02-136325
-
(2008)
Blood
, vol.112
, pp. 1822-1831
-
-
Novitskiy, S.V.1
Ryzhov, S.2
Zaynagetdinov, R.3
Goldstein, A.E.4
Huang, Y.5
Tikhomirov, O.Y.6
-
43
-
-
85026737480
-
Constitutive IDO1 expression in human tumors is driven by cyclooxygenase-2 and mediates intrinsic immune resistance
-
Hennequart M, Pilotte L, Cane S, Hoffmann D, Stroobant V, De Plaen E, et al. Constitutive IDO1 expression in human tumors is driven by cyclooxygenase-2 and mediates intrinsic immune resistance. Cancer Immunol Res (2017) 5:695-709. doi:10.1158/2326-6066.CIR-16-0400
-
(2017)
Cancer Immunol Res
, vol.5
, pp. 695-709
-
-
Hennequart, M.1
Pilotte, L.2
Cane, S.3
Hoffmann, D.4
Stroobant, V.5
De Plaen, E.6
-
45
-
-
84863354166
-
Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy
-
Wang D, Saga Y, Mizukami H, Sato N, Nonaka H, Fujiwara H, et al. Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy. Int J Oncol (2012) 40:929-34. doi:10.3892/ijo.2011.1295
-
(2012)
Int J Oncol
, vol.40
, pp. 929-934
-
-
Wang, D.1
Saga, Y.2
Mizukami, H.3
Sato, N.4
Nonaka, H.5
Fujiwara, H.6
-
46
-
-
0037090313
-
Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses
-
Mellor AL, Keskin DB, Johnson T, Chandler P, Munn DH. Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. J Immunol (2002) 168:3771-6. doi:10.4049/jimmunol.168.8.3771
-
(2002)
J Immunol
, vol.168
, pp. 3771-3776
-
-
Mellor, A.L.1
Keskin, D.B.2
Johnson, T.3
Chandler, P.4
Munn, D.H.5
-
47
-
-
84979536652
-
Tolerogenic phenotype of IFN-γ-induced IDO+ dendritic cells is maintained via an autocrine IDO-kynurenine/AhR-IDO loop
-
Li Q, Harden JL, Anderson CD, Egilmez NK. Tolerogenic phenotype of IFN-γ-induced IDO+ dendritic cells is maintained via an autocrine IDO-kynurenine/AhR-IDO loop. J Immunol (2016) 197:962-70. doi:10.4049/jimmunol.1502615
-
(2016)
J Immunol
, vol.197
, pp. 962-970
-
-
Li, Q.1
Harden, J.L.2
Anderson, C.D.3
Egilmez, N.K.4
-
48
-
-
84944045501
-
Tumor-expressed IDO recruits and activates MDSCs in a treg-dependent manner
-
Holmgaard RB, Zamarin D, Li Y, Gasmi B, Munn DH, Allison JP, et al. Tumor-expressed IDO recruits and activates MDSCs in a treg-dependent manner. Cell Rep (2015) 13:412-24. doi:10.1016/j.celrep.2015.08.077
-
(2015)
Cell Rep
, vol.13
, pp. 412-424
-
-
Holmgaard, R.B.1
Zamarin, D.2
Li, Y.3
Gasmi, B.4
Munn, D.H.5
Allison, J.P.6
-
50
-
-
34047220868
-
Cancer immunoediting: from immune surveillance to immune escape
-
Kim R, Emi M, Tanabe K. Cancer immunoediting: from immune surveillance to immune escape. Immunology (2007) 121:1-17. doi:10.1111/j.1365-2567.2007.02587.x
-
(2007)
Immunology
, vol.121
, pp. 1-17
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
-
51
-
-
2542430341
-
The three Es of cancer immunoediting
-
Dunn GP, Old LJ, Schreiber RD. The three Es of cancer immunoediting. Annu Rev Immunol (2004) 22:329-60. doi:10.1146/annurev.immunol.22.012703.104803
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 329-360
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
52
-
-
84993929137
-
Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies
-
Shou D, Liang W, Song Z, Yin J, Sun Q, Gong W. Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies. Oncotarget (2016) 7:64505-11. doi:10.18632/oncotarget.11352
-
(2016)
Oncotarget
, vol.7
, pp. 64505-64511
-
-
Shou, D.1
Liang, W.2
Song, Z.3
Yin, J.4
Sun, Q.5
Gong, W.6
-
53
-
-
84863012436
-
Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-associated macrophages
-
Zhao Q, Kuang D-M, Wu Y, Xiao X, Li X-F, Li T-J, et al. Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-associated macrophages. J Immunol (2012) 188:1117-24. doi:10.4049/jimmunol.1100164
-
(2012)
J Immunol
, vol.188
, pp. 1117-1124
-
-
Zhao, Q.1
Kuang, D-M.2
Wu, Y.3
Xiao, X.4
Li, X-F.5
Li, T-J.6
-
54
-
-
23844451052
-
Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells
-
Okamoto A, Nikaido T, Ochiai K, Takakura S, Saito M, Aoki Y, et al. Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells. Clin Cancer Res (2005) 11:6030-9. doi:10.1158/1078-0432.CCR-04-2671
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6030-6039
-
-
Okamoto, A.1
Nikaido, T.2
Ochiai, K.3
Takakura, S.4
Saito, M.5
Aoki, Y.6
-
55
-
-
84975117196
-
Analysis of kynurenine/tryptophan ratio and expression of IDO1 and 2 mRNA in tumour tissue of cervical cancer patients
-
Hascitha J, Priya R, Jayavelu S, Dhandapani H, Selvaluxmy G, Sunder Singh S, et al. Analysis of kynurenine/tryptophan ratio and expression of IDO1 and 2 mRNA in tumour tissue of cervical cancer patients. Clin Biochem (2016) 49:919-24. doi:10.1016/j.clinbiochem.2016.04.008
-
(2016)
Clin Biochem
, vol.49
, pp. 919-924
-
-
Hascitha, J.1
Priya, R.2
Jayavelu, S.3
Dhandapani, H.4
Selvaluxmy, G.5
Sunder Singh, S.6
-
56
-
-
85033491718
-
Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival
-
Zhai L, Ladomersky E, Lauing KL, Wu M, Genet M, Gritsina G, et al. Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival. Clin Cancer Res (2017) 23:6650-60. doi:10.1158/1078-0432.CCR-17-0120
-
(2017)
Clin Cancer Res
, vol.23
, pp. 6650-6660
-
-
Zhai, L.1
Ladomersky, E.2
Lauing, K.L.3
Wu, M.4
Genet, M.5
Gritsina, G.6
-
57
-
-
84994386116
-
Improved radiosynthesis and biological evaluations of L- and D-1-[18F]fluoroethyl-tryptophan for PET imaging of IDO-mediated kynurenine pathway of tryptophan metabolism
-
Xin Y, Cai H. Improved radiosynthesis and biological evaluations of L- and D-1-[18F]fluoroethyl-tryptophan for PET imaging of IDO-mediated kynurenine pathway of tryptophan metabolism. Mol Imaging Biol (2017) 19:589-98. doi:10.1007/s11307-016-1024-z
-
(2017)
Mol Imaging Biol
, vol.19
, pp. 589-598
-
-
Xin, Y.1
Cai, H.2
-
58
-
-
84962909909
-
Fully automated radiosynthesis of N1-[18F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging
-
Henrottin J, Lemaire C, Egrise D, Zervosen A, van Den Eynde B, Plenevaux A, et al. Fully automated radiosynthesis of N1-[18F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging. Nucl Med Biol (2016) 43:379-89. doi:10.1016/j.nucmedbio.2016.03.001
-
(2016)
Nucl Med Biol
, vol.43
, pp. 379-389
-
-
Henrottin, J.1
Lemaire, C.2
Egrise, D.3
Zervosen, A.4
van Den Eynde, B.5
Plenevaux, A.6
-
59
-
-
84959292227
-
IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance
-
Munn DH, Mellor AL. IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance. Trends Immunol (2016) 37:193-207. doi:10.1016/j.it.2016.01.002
-
(2016)
Trends Immunol
, vol.37
, pp. 193-207
-
-
Munn, D.H.1
Mellor, A.L.2
-
60
-
-
85009411841
-
The kynurenine pathway is a double-edged sword in immune-privileged sites and in cancer: implications for immunotherapy
-
Routy JP, Routy B, Graziani GM, Mehraj V. The kynurenine pathway is a double-edged sword in immune-privileged sites and in cancer: implications for immunotherapy. Int J Tryptophan Res (2016) 9:67-77. doi:10.4137/IJTR.S38355
-
(2016)
Int J Tryptophan Res
, vol.9
, pp. 67-77
-
-
Routy, J.P.1
Routy, B.2
Graziani, G.M.3
Mehraj, V.4
-
61
-
-
84879880747
-
Therapeutic gene modified cell based cancer vaccines
-
Kozlowska A, Mackiewicz J, Mackiewicz A. Therapeutic gene modified cell based cancer vaccines. Gene (2013) 525:200-7. doi:10.1016/j.gene.2013.03.056
-
(2013)
Gene
, vol.525
, pp. 200-207
-
-
Kozlowska, A.1
Mackiewicz, J.2
Mackiewicz, A.3
-
62
-
-
85015363472
-
The rationale of indoleamine 2,3-dioxygenase inhibition for cancer therapy
-
Brochez L, Chevolet I, Kruse V. The rationale of indoleamine 2,3-dioxygenase inhibition for cancer therapy. Eur J Cancer (2017) 76:167-82. doi:10.1016/j.ejca.2017.01.011
-
(2017)
Eur J Cancer
, vol.76
, pp. 167-182
-
-
Brochez, L.1
Chevolet, I.2
Kruse, V.3
-
63
-
-
84921398751
-
Trial watch: IDO inhibitors in cancer therapy
-
Vacchelli E, Aranda F, Eggermont A, Sautès-Fridman C, Tartour E, Kennedy EP, et al. Trial watch: IDO inhibitors in cancer therapy. Oncoimmunology (2014) 3:e957994. doi:10.4161/21624011.2014.957994
-
(2014)
Oncoimmunology
, vol.3
-
-
Vacchelli, E.1
Aranda, F.2
Eggermont, A.3
Sautès-Fridman, C.4
Tartour, E.5
Kennedy, E.P.6
-
64
-
-
85039046206
-
Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells
-
Liu Y, Liang X, Yin X, Lv J, Tang K, Ma J, et al. Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells. Nat Commun (2017) 8:15207. doi:10.1038/ncomms15207
-
(2017)
Nat Commun
, vol.8
, pp. 15207
-
-
Liu, Y.1
Liang, X.2
Yin, X.3
Lv, J.4
Tang, K.5
Ma, J.6
-
65
-
-
85017184437
-
Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma
-
Garg AD, Vandenberk L, Van Woensel M, Belmans J, Schaaf M, Boon L, et al. Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma. Oncoimmunology (2017) 6:e1295903. doi:10.1080/2162402X.2017.1295903
-
(2017)
Oncoimmunology
, vol.6
-
-
Garg, A.D.1
Vandenberk, L.2
Van Woensel, M.3
Belmans, J.4
Schaaf, M.5
Boon, L.6
-
66
-
-
84871232968
-
Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth
-
Blache CA, Manuel ER, Kaltcheva TI, Wong AN, Ellenhorn JDI, Blazar BR, et al. Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth. Cancer Res (2012) 72:6447-56. doi:10.1158/0008-5472.CAN-12-0193
-
(2012)
Cancer Res
, vol.72
, pp. 6447-6456
-
-
Blache, C.A.1
Manuel, E.R.2
Kaltcheva, T.I.3
Wong, A.N.4
Ellenhorn, J.D.I.5
Blazar, B.R.6
-
67
-
-
84886943979
-
A road less traveled paved by IDO silencing: harnessing the antitumor activity of neutrophils
-
Manuel ER, Diamond DJ. A road less traveled paved by IDO silencing: harnessing the antitumor activity of neutrophils. Oncoimmunology (2013) 2:e23322. doi:10.4161/onci.23322
-
(2013)
Oncoimmunology
, vol.2
-
-
Manuel, E.R.1
Diamond, D.J.2
|