메뉴 건너뛰기




Volumn 42, Issue 7, 2018, Pages 1156-1167

Faecalibacterium prausnitzii and a Prebiotic Protect Intestinal Health in a Mouse Model of Antibiotic and Clostridium difficile Exposure

Author keywords

antibiotics; butyrate, Clostridium difficile, innate immunity, intestine, microbiome, prebiotic, probiotics

Indexed keywords

ANTIBIOTIC AGENT; CEFOXITIN; CLINDAMYCIN; METRONIDAZOLE; PIPERACILLIN PLUS TAZOBACTAM; PREBIOTIC AGENT; TIGHT JUNCTION PROTEIN; VANCOMYCIN; ANION TRANSPORT PROTEIN; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; BUTYRIC ACID DERIVATIVE; CLOSTRIDIUM DIFFICILE ENTEROTOXIN B RECEPTOR; CYTOKINE; IMMUNOGLOBULIN RECEPTOR; PROBIOTIC AGENT; STARCH;

EID: 85041190343     PISSN: 01486071     EISSN: 19412444     Source Type: Journal    
DOI: 10.1002/jpen.1053     Document Type: Article
Times cited : (46)

References (45)
  • 1
    • 84983605323 scopus 로고    scopus 로고
    • Cost of hospital management of Clostridium difficile infection in United States—a meta-analysis and modelling study
    • Zhang S, Palazuelos-Munoz S, Balsells EM, Nair H, Chit A, Kyaw MH. Cost of hospital management of Clostridium difficile infection in United States—a meta-analysis and modelling study. BMC Infect Dis. 2016;16:447
    • (2016) BMC Infect Dis , vol.16 , pp. 447
    • Zhang, S.1    Palazuelos-Munoz, S.2    Balsells, E.M.3    Nair, H.4    Chit, A.5    Kyaw, M.H.6
  • 2
    • 0037871799 scopus 로고    scopus 로고
    • Guidelines for environmental infection control in health-care facilities
    • Available from
    • Sehulster L, Chinn RYW. Guidelines for environmental infection control in health-care facilities. MMWR Recomm Rep. 2003;52(RR10):1-42. Available from: http://www.cdc.gov/HAI/organisms/cdiff/Cdiff_excerpt.html
    • (2003) MMWR Recomm Rep , vol.52 , Issue.RR10 , pp. 1-42
    • Sehulster, L.1    Chinn, R.Y.W.2
  • 3
    • 84881270083 scopus 로고    scopus 로고
    • Commensal Clostridia: leading players in the maintenance of gut homeostasis
    • Lopetuso LR, Scaldaferri F, Petito V, Gasbarrini A. Commensal Clostridia: leading players in the maintenance of gut homeostasis. Gut Pathogens. 2013;5:23
    • (2013) Gut Pathogens , vol.5 , pp. 23
    • Lopetuso, L.R.1    Scaldaferri, F.2    Petito, V.3    Gasbarrini, A.4
  • 6
    • 0036399823 scopus 로고    scopus 로고
    • How host-microbial interactions shape the nutrient environment of the mammalian intestine
    • Hooper L, Midtvedt T, Gordon J. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr. 2002;22:283-307
    • (2002) Annu Rev Nutr , vol.22 , pp. 283-307
    • Hooper, L.1    Midtvedt, T.2    Gordon, J.3
  • 7
    • 84863719891 scopus 로고    scopus 로고
    • Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection
    • Brandt LJ, Aroniadis OC, Mellow M, et al. Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection. Am J Gastroenterol. 2012;107:1079-1087
    • (2012) Am J Gastroenterol , vol.107 , pp. 1079-1087
    • Brandt, L.J.1    Aroniadis, O.C.2    Mellow, M.3
  • 8
    • 84892894991 scopus 로고    scopus 로고
    • Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection
    • Theriot CM, Koenigsknecht MJ, Carlson PE, et al. Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection. Nat Commun. 2014;5:3114
    • (2014) Nat Commun , vol.5 , pp. 3114
    • Theriot, C.M.1    Koenigsknecht, M.J.2    Carlson, P.E.3
  • 9
    • 84882779621 scopus 로고    scopus 로고
    • Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea
    • Antharam VC, Li EC, Ishmael A, et al. Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea. J Clin Microbiol. 2013;51:2884-2892
    • (2013) J Clin Microbiol , vol.51 , pp. 2884-2892
    • Antharam, V.C.1    Li, E.C.2    Ishmael, A.3
  • 10
    • 84868158515 scopus 로고    scopus 로고
    • Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice
    • Lawley TD, Clare S, Walker AW, et al. Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. PLoS Pathog. 2012;8:e1002995
    • (2012) PLoS Pathog , vol.8
    • Lawley, T.D.1    Clare, S.2    Walker, A.W.3
  • 14
    • 66149084058 scopus 로고    scopus 로고
    • GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
    • Thangaraju M, Cresci G, Anath S, Digby G, Lambert N, Mellinger J, Ganapathy V. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. Cancer Res. 2009;69:2826-2832
    • (2009) Cancer Res , vol.69 , pp. 2826-2832
    • Thangaraju, M.1    Cresci, G.2    Anath, S.3    Digby, G.4    Lambert, N.5    Mellinger, J.6    Ganapathy, V.7
  • 15
    • 77951932119 scopus 로고    scopus 로고
    • Role of colonic short-chain fatty acid transport and diarrhea
    • Binder HJ. Role of colonic short-chain fatty acid transport and diarrhea. Annu Rev Physiol. 2010;72:297-313
    • (2010) Annu Rev Physiol , vol.72 , pp. 297-313
    • Binder, H.J.1
  • 16
    • 84862870885 scopus 로고    scopus 로고
    • Microbial butyrate and its role for barrier function in the gastrointestinal tract
    • Ploger S, Stumpff F, Penner G, et al. Microbial butyrate and its role for barrier function in the gastrointestinal tract. Ann NY Acad Sci. 2012;1258:52-59
    • (2012) Ann NY Acad Sci , vol.1258 , pp. 52-59
    • Ploger, S.1    Stumpff, F.2    Penner, G.3
  • 17
    • 0034062353 scopus 로고    scopus 로고
    • The luminal short-chain fatty acid butyrate modulates NF-κB activity in a human colonic epithelial cell line
    • Inan MS, Rasoulpour RJ, Yin L, Hubbard AK, Rosenberg DW, Giardina C. The luminal short-chain fatty acid butyrate modulates NF-κB activity in a human colonic epithelial cell line. Gastroenterology 2000;118:724-734
    • (2000) Gastroenterology , vol.118 , pp. 724-734
    • Inan, M.S.1    Rasoulpour, R.J.2    Yin, L.3    Hubbard, A.K.4    Rosenberg, D.W.5    Giardina, C.6
  • 18
    • 0031042629 scopus 로고    scopus 로고
    • Lack of butyrate is associated with induction of Bax and subsequent apoptosis in the proximal colon of guinea pig
    • Hass R, Busche R, Luciano L, Reale E, Engelhardt WV. Lack of butyrate is associated with induction of Bax and subsequent apoptosis in the proximal colon of guinea pig. Gastroenterology 1997;112:875-881
    • (1997) Gastroenterology , vol.112 , pp. 875-881
    • Hass, R.1    Busche, R.2    Luciano, L.3    Reale, E.4    Engelhardt, W.V.5
  • 19
    • 84905675648 scopus 로고    scopus 로고
    • Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic
    • Hill C, Guarner F, Reid G, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014;11:506-514
    • (2014) Nat Rev Gastroenterol Hepatol , vol.11 , pp. 506-514
    • Hill, C.1    Guarner, F.2    Reid, G.3
  • 20
    • 84881559009 scopus 로고    scopus 로고
    • Faecalibaterium prausnitzii and human intestinal health
    • Miquel S, Martin R, Rossi O, et al. Faecalibaterium prausnitzii and human intestinal health. Curr Opin Microbiol. 2014;16:255-261
    • (2014) Curr Opin Microbiol , vol.16 , pp. 255-261
    • Miquel, S.1    Martin, R.2    Rossi, O.3
  • 22
    • 0036866628 scopus 로고    scopus 로고
    • Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb.nov
    • Duncan SH, Hold GL, Harmsen H, Stewart CS, Flint HJ. Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb.nov. Int J Syst Evol Microbiol. 2002;52:2141-2146
    • (2002) Int J Syst Evol Microbiol , vol.52 , pp. 2141-2146
    • Duncan, S.H.1    Hold, G.L.2    Harmsen, H.3    Stewart, C.S.4    Flint, H.J.5
  • 23
    • 33646585117 scopus 로고    scopus 로고
    • Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut
    • Belenguer A, Duncan SH, Calder AG, Holtrop G, Louis P, Lobley GE, Flint HJ. Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut. Appl Environ Microbiol 2006;72:3593-3599
    • (2006) Appl Environ Microbiol , vol.72 , pp. 3593-3599
    • Belenguer, A.1    Duncan, S.H.2    Calder, A.G.3    Holtrop, G.4    Louis, P.5    Lobley, G.E.6    Flint, H.J.7
  • 24
  • 25
    • 23044492161 scopus 로고    scopus 로고
    • Effect of antibiotic treatment on growth of and toxin production by Clostridium difficile in the cecal contents of mice
    • Pultz NJ, Donskey CJ. Effect of antibiotic treatment on growth of and toxin production by Clostridium difficile in the cecal contents of mice. Antimicrob Agents Chemother. 2005;49:3529-3532
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3529-3532
    • Pultz, N.J.1    Donskey, C.J.2
  • 26
    • 77950516928 scopus 로고    scopus 로고
    • Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8
    • Cresci G, Thangaraju M, Mellinger J, Liu K, Ganapathy V. Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8. J Gastrointest Surg. 2010;14:449-461
    • (2010) J Gastrointest Surg , vol.14 , pp. 449-461
    • Cresci, G.1    Thangaraju, M.2    Mellinger, J.3    Liu, K.4    Ganapathy, V.5
  • 27
    • 84887227527 scopus 로고    scopus 로고
    • Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury
    • Cresci G, Nagy L, Ganapathy V. Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury. J Parent Enteral Nutr. 2013;37:763-774
    • (2013) J Parent Enteral Nutr , vol.37 , pp. 763-774
    • Cresci, G.1    Nagy, L.2    Ganapathy, V.3
  • 29
    • 84992391514 scopus 로고    scopus 로고
    • Frizzled proteins are colonic epithelial receptors for C. difficile B
    • Tao L, Zhang J, Meraner P, et al. Frizzled proteins are colonic epithelial receptors for C. difficile B. Nature. 2016;538:350-355
    • (2016) Nature , vol.538 , pp. 350-355
    • Tao, L.1    Zhang, J.2    Meraner, P.3
  • 30
    • 85007575443 scopus 로고    scopus 로고
    • Complete microbiota engraftment is not essential for recovery from recurrent Clostridium difficile infection following fecal microbiota transplantation
    • Staley C, Kelly CR, Brandt LJ, Khoruts A, Sadowsky MJ. Complete microbiota engraftment is not essential for recovery from recurrent Clostridium difficile infection following fecal microbiota transplantation. mBio. 2016;7:e01965-16
    • (2016) mBio , vol.7 , pp. e1916-e1965
    • Staley, C.1    Kelly, C.R.2    Brandt, L.J.3    Khoruts, A.4    Sadowsky, M.J.5
  • 31
    • 84857067037 scopus 로고    scopus 로고
    • Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis
    • Buffie CG, Jarchum I, Equinda M, et al. Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis. Infect Immun. 2012;80:62-73
    • (2012) Infect Immun , vol.80 , pp. 62-73
    • Buffie, C.G.1    Jarchum, I.2    Equinda, M.3
  • 32
    • 2342586106 scopus 로고    scopus 로고
    • Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B
    • Hayashi H, Szaszi K, Coady-Osberg N, et al. Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. J Gen Physiol. 2004;123:491-504
    • (2004) J Gen Physiol , vol.123 , pp. 491-504
    • Hayashi, H.1    Szaszi, K.2    Coady-Osberg, N.3
  • 33
    • 84912016691 scopus 로고    scopus 로고
    • The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection
    • Sun X, Hirota SA. The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection. Mol Immunol. 2015;63:193-202
    • (2015) Mol Immunol , vol.63 , pp. 193-202
    • Sun, X.1    Hirota, S.A.2
  • 34
    • 84924247475 scopus 로고    scopus 로고
    • Lactobacillus rhamnosus CNCM I-3690 and the commensal bacterium Faecalibacterium prausnitzii A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice
    • Laval L, Martin R, Natividad JN, et al. Lactobacillus rhamnosus CNCM I-3690 and the commensal bacterium Faecalibacterium prausnitzii A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice. Gut Microbes. 2015;6:1-9
    • (2015) Gut Microbes , vol.6 , pp. 1-9
    • Laval, L.1    Martin, R.2    Natividad, J.N.3
  • 35
    • 84878317467 scopus 로고    scopus 로고
    • Markers of intestinal inflammation, not bacterial burden, correlate with clinical outcomes in Clostridium difficile infection
    • El Feghaly R, Stauber JL, Deych E, Gonzalez C, Tarr PI, Haslam DB. Markers of intestinal inflammation, not bacterial burden, correlate with clinical outcomes in Clostridium difficile infection. J Clin Dis. 2013;56:1713-1721
    • (2013) J Clin Dis , vol.56 , pp. 1713-1721
    • El Feghaly, R.1    Stauber, J.L.2    Deych, E.3    Gonzalez, C.4    Tarr, P.I.5    Haslam, D.B.6
  • 36
    • 79955048935 scopus 로고    scopus 로고
    • Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen
    • Hasegawa M, Yamazaki T, Kamada N, et al. Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen. J Immunol. 2011;186:4872-4880
    • (2011) J Immunol , vol.186 , pp. 4872-4880
    • Hasegawa, M.1    Yamazaki, T.2    Kamada, N.3
  • 37
    • 79959828804 scopus 로고    scopus 로고
    • A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins
    • Ryan A, Lynch M, Smith SM, et al. A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins. PLoS Pathog. 2011;7:e1002076
    • (2011) PLoS Pathog , vol.7
    • Ryan, A.1    Lynch, M.2    Smith, S.M.3
  • 38
    • 84867605854 scopus 로고    scopus 로고
    • Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis
    • Jarchum I, Liu M, Shi C, Equinda M, Pamer EG. Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis. Infect Immun. 2012;80:2989-2996
    • (2012) Infect Immun , vol.80 , pp. 2989-2996
    • Jarchum, I.1    Liu, M.2    Shi, C.3    Equinda, M.4    Pamer, E.G.5
  • 39
    • 84969919884 scopus 로고    scopus 로고
    • The microbiota and immune response during Clostridium difficile infection
    • Buonomo EL, Petri WA. The microbiota and immune response during Clostridium difficile infection. Anaerobe 2016;14:79-84
    • (2016) Anaerobe , vol.14 , pp. 79-84
    • Buonomo, E.L.1    Petri, W.A.2
  • 40
    • 33750488134 scopus 로고    scopus 로고
    • Mucosal IL-8 and TGFβ recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells
    • Smythies LE, Maheshwari A, Clements R, et al. Mucosal IL-8 and TGFβ recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells. J Leukoc Biol. 2006;80:492-499
    • (2006) J Leukoc Biol , vol.80 , pp. 492-499
    • Smythies, L.E.1    Maheshwari, A.2    Clements, R.3
  • 41
    • 80355146868 scopus 로고    scopus 로고
    • Monocyte recruitment during infection and inflammation
    • Shi C, Pamer EG. Monocyte recruitment during infection and inflammation. Nat Rev Immunol. 2011;11:762-774
    • (2011) Nat Rev Immunol , vol.11 , pp. 762-774
    • Shi, C.1    Pamer, E.G.2
  • 42
    • 0036668692 scopus 로고    scopus 로고
    • Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium
    • Perner A, Andresen L, Normark M, Rask-Madsen J. Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium. Scand J Gastroenterol. 2002;37:944-948
    • (2002) Scand J Gastroenterol , vol.37 , pp. 944-948
    • Perner, A.1    Andresen, L.2    Normark, M.3    Rask-Madsen, J.4
  • 43
    • 84918843257 scopus 로고    scopus 로고
    • Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages
    • Rath M, Muller I, Kropf P, Closs EI, Munder M. Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages. Front Immunol. 2014;5:532
    • (2014) Front Immunol , vol.5 , pp. 532
    • Rath, M.1    Muller, I.2    Kropf, P.3    Closs, E.I.4    Munder, M.5
  • 44
    • 80052755511 scopus 로고    scopus 로고
    • Commensla gut flora reduces susceptibiolity to experimentally induced colitis via T-cell-derived interleukin-10
    • Pils MC, Bleich A, Prinz I, et al. Commensla gut flora reduces susceptibiolity to experimentally induced colitis via T-cell-derived interleukin-10. Inflamm Bowel Dis. 2011;10:2038-2046
    • (2011) Inflamm Bowel Dis , vol.10 , pp. 2038-2046
    • Pils, M.C.1    Bleich, A.2    Prinz, I.3
  • 45
    • 84928775824 scopus 로고    scopus 로고
    • Identification of Metabolic signatures linked to anti-inflammatory effects of Faecalibacterium prausnitzii
    • Miquel S, Leclerc M, Martin R, et al. Identification of Metabolic signatures linked to anti-inflammatory effects of Faecalibacterium prausnitzii. mBio. 2015;6:e00300-15
    • (2015) mBio , vol.6 , pp. e00300-e00315
    • Miquel, S.1    Leclerc, M.2    Martin, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.