Faecalibacterium prausnitzii and human intestinal health

Current Opinion in Microbiology

Volumn 16, Issue 3, 2013, Pages 255-261

  Miquel, S ^a   Martin R ^a   Rossi, O ^b   Bermudez Humaran L G ^a   Chatel, J M ^a   Sokol, H ^a,c,d   Thomas, M ^a   Wells, J M ^b   Langella, P ^a  

^a UMR1319 MICALIS   (France)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c Centre National de la Recherche Scientifique   (France)

^d HÔPITAL SAINT ANTOINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TRINITROBENZENESULFONIC ACID;

BACTERIAL STRAIN; BACTERIUM; BACTERIUM CULTURE; CELIAC DISEASE; COMMENSAL; FAECALIBACTERIUM PRAUSNITZII; HUMAN; IMMUNITY; INTESTINE; INTESTINE FLORA; IRRITABLE COLON; MICROFLORA; NONHUMAN; OBESITY; REVIEW; SUPERNATANT;

BACTERIA (MICROORGANISMS); FAECALIBACTERIUM PRAUSNITZII; MUS;

EID: 84881559009     PISSN: 13695274     EISSN: 18790364     Source Type: Journal    
DOI: 10.1016/j.mib.2013.06.003     Document Type: Review

References (62)

1. Wang R.F., Cao W.W., Cerniglia C.E. Phylogenetic analysis of Fusobacterium prausnitzii based upon the 16S rRNA gene sequence and PCR confirmation. Int J Syst Bacteriol 1996, 46:341-343.
2. Suau A., Bonnet R., Sutren M., Godon J.J., Gibson G.R., Collins M.D., Dore J. Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut. Appl Environ Microbiol 1999, 65:4799-4807.
3. Duncan S.H., Hold G.L., Harmsen H.J., Stewart C.S., Flint H.J. Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov. Int J Syst Evol Microbiol 2002, 52:2141-2146.
4. Lopez-Siles M., Khan T.M., Duncan S.H., Harmsen H.J., Garcia-Gil L.J., Flint H.J. Cultured representatives of two major phylogroups of human colonic Faecalibacterium prausnitzii can utilize pectin, uronic acids, and host-derived substrates for growth. Appl Environ Microbiol 2012, 78:420-428.
5. Duncan S.H., Louis P., Flint H.J. Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl Environ Microbiol 2004, 70:5810-5817.
6. Khan M.T., Duncan S.H., Stams A.J., van Dijl J.M., Flint H.J., Harmsen H.J. The gut anaerobe Faecalibacterium prausnitzii uses an extracellular electron shuttle to grow at oxic-anoxic interphases. ISME J 2012, 6:1578-1585.
7. Lay C., Sutren M., Rochet V., Saunier K., Dore J., Rigottier-Gois L. Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota. Environ Microbiol 2005, 7:933-946.
8. Hold G.L., Schwiertz A., Aminov R.I., Blaut M., Flint H.J. Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces. Appl Environ Microbiol 2003, 69:4320-4324.
9. Castillo M., Skene G., Roca M., Anguita M., Badiola I., Duncan S.H., Flint H.J., Martin-Orue S.M. Application of 16S rRNA gene-targetted fluorescence in situ hybridization and restriction fragment length polymorphism to study porcine microbiota along the gastrointestinal tract in response to different sources of dietary fibre. FEMS Microbiol Ecol 2007, 59:138-146.
10. Nava G.M., Stappenbeck T.S. Diversity of the autochthonous colonic microbiota. Gut Microbes 2011, 2.
11. Oikonomou G., Teixeira A.G., Foditsch C., Bicalho M.L., Machado V.S., Bicalho R.C. Fecal microbial diversity in pre-weaned dairy calves as described by pyrosequencing of metagenomic 16S rDNA. Associations of Faecalibacterium species with health and growth. PLoS ONE 2013, 8:e63157.
12. Bjerrum L., Engberg R.M., Leser T.D., Jensen B.B., Finster K., Pedersen K. Microbial community composition of the ileum and cecum of broiler chickens as revealed by molecular and culture-based techniques. Poult Sci 2006, 85:1151-1164.
13. Scupham A.J. Succession in the intestinal microbiota of preadolescent turkeys. FEMS Microbiol Ecol 2007, 60:136-147.
14. Foglesong M.A., Cruden D.L., Markovetz A.J. Pleomorphism of fusobacteria isolated from the cockroach hindgut. J Bacteriol 1984, 158:474-480.
15. Li M., Wang B., Zhang M., Rantalainen M., Wang S., Zhou H., Zhang Y., Shen J., Pang X., Zhang M., et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci U S A 2008, 105:2117-2122.
16. Wrzosek L.M.S., Noordine M.L., Bouet S., Joncquel Chevalier-Curt M., Robert V., Philippe C., Bridonneau C., Cherbuy C., Robbe-Masselot C., Langella P., Thomas M. Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. BMC Biology 2013, 11.
17. Flint H.J., Scott K.P., Duncan S.H., Louis P., Forano E. Microbial degradation of complex carbohydrates in the gut. Gut Microbes 2012, 3:289-306.
18. Macfarlane G.T., Macfarlane S. Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics. J Clin Gastroenterol 2011, 45(Suppl.):S120-S127.
19. Ploger S., Stumpff F., Penner G.B., Schulzke J.D., Gabel G., Martens H., Shen Z., Gunzel D., Aschenbach J.R. Microbial butyrate and its role for barrier function in the gastrointestinal tract. Ann N Y Acad Sci 2012, 1258:52-59.
20. Hudcovic T., Kolinska J., Klepetar J., Stepankova R., Rezanka T., Srutkova D., Schwarzer M., Erban V., Du Z., Wells J.M., et al. Protective effect of Clostridium tyrobutyricum in acute dextran sodium sulphate-induced colitis: differential regulation of tumour necrosis factor-alpha and interleukin-18 in BALB/c and severe combined immunodeficiency mice. Clin Exp Immunol 2012, 167:356-365.
21. Sokol H., Pigneur B., Watterlot L., Lakhdari O., Bermudez-Humaran L.G., Gratadoux J.J., Blugeon S., Bridonneau C., Furet J.P., Corthier G., et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2008, 105:16731-16736.
22. Sokol H., Seksik P., Furet J.P., Firmesse O., Nion-Larmurier I., Beaugerie L., Cosnes J., Corthier G., Marteau P., Dore J. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis 2009, 15:1183-1189.
23. Swidsinski A., Loening-Baucke V., Vaneechoutte M., Doerffel Y. Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora. Inflamm Bowel Dis 2008, 14:147-161.
24. Willing B., Halfvarson J., Dicksved J., Rosenquist M., Jarnerot G., Engstrand L., Tysk C., Jansson J.K. Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis 2009, 15:653-660.
25. Maccaferri S., Vitali B., Klinder A., Kolida S., Ndagijimana M., Laghi L., Calanni F., Brigidi P., Gibson G.R., Costabile A. Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in vitro approach using a continuous culture colonic model system. J Antimicrob Chemother 2010, 65:2556-2565.
26. Dorffel Y., Swidsinski A., Loening-Baucke V., Wiedenmann B., Pavel M. Common biostructure of the colonic microbiota in neuroendocrine tumors and Crohn's disease and the effect of therapy. Inflamm Bowel Dis 2011, 18:1663-1671.
27. Rajilic-Stojanovic M., Biagi E., Heilig H.G., Kajander K., Kekkonen R.A., Tims S., de Vos W.M. Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology 2011, 141:1792-1801.
28. Duboc H., Rainteau D., Rajca S., Humbert L., Farabos D., Maubert M., Grondin V., Jouet P., Bouhassira D., Seksik P., et al. Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome. Neurogastroenterol Motil 2012, 24:513-520. e246-e517.
29. Rigsbee L., Agans R., Shankar V., Kenche H., Khamis H.J., Michail S., Paliy O. Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrome. Am J Gastroenterol 2012, 107:1740-1751.
30. Blaut M., Klaus S. Intestinal microbiota and obesity. Handb Exp Pharmacol 2012, 251-273.
31. Furet J.P., Kong L.C., Tap J., Poitou C., Basdevant A., Bouillot J.L., Mariat D., Corthier G., Dore J., Henegar C., et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes 2010, 59:3049-3057.
32. Graessler J., Qin Y., Zhong H., Zhang J., Licinio J., Wong M.L., Xu A., Chavakis T., Bornstein A.B., Ehrhart-Bornstein M., et al. Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters. Pharmacogenomics J 2012, 10.1038/tpj.2012.43.
33. Balamurugan R., George G., Kabeerdoss J., Hepsiba J., Chandragunasekaran A.M., Ramakrishna B.S. Quantitative differences in intestinal Faecalibacterium prausnitzii in obese Indian children. Br J Nutr 2010, 103:335-338.
34. De Palma G., Nadal I., Medina M., Donat E., Ribes-Koninckx C., Calabuig M., Sanz Y. Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children. BMC Microbiol 2010, 10:63.
35. De Palma G., Nadal I., Collado M.C., Sanz Y. Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects. Br J Nutr 2009, 102:1154-1160.
36. Nadal I., Donat E., Ribes-Koninckx C., Calabuig M., Sanz Y. Imbalance in the composition of the duodenal microbiota of children with coeliac disease. J Med Microbiol 2007, 56:1669-1674.
37. Candela M., Rampelli S., Turroni S., Severgnini M., Consolandi C., De Bellis G., Masetti R., Ricci G., Pession A., Brigidi P. Unbalance of intestinal microbiota in atopic children. BMC Microbiol 2012, 12:95.
38. Swidsinski A., Loening-Baucke V., Verstraelen H., Osowska S., Doerffel Y. Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea. Gastroenterology 2008, 135:568-579.
39. Swidsinski A., Dorffel Y., Loening-Baucke V., Theissig F., Ruckert J.C., Ismail M., Rau W.A., Gaschler D., Weizenegger M., Kuhn S., et al. Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum. Gut 2011, 60:34-40.
40. Wu Z.W., Ling Z.X., Lu H.F., Zuo J., Sheng J.F., Zheng S.S., Li L.J. Changes of gut bacteria and immune parameters in liver transplant recipients. Hepatobiliary Pancreat Dis Int 2012, 11:40-50.
41. Sobhani I., Tap J., Roudot-Thoraval F., Roperch J.P., Letulle S., Langella P., Corthier G., Tran Van Nhieu J., Furet J.P. Microbial dysbiosis in colorectal cancer (CRC) patients. PLoS ONE 2011, 6:e16393.
42. Murai M., Turovskaya O., Kim G., Madan R., Karp C.L., Cheroutre H., Kronenberg M. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat Immunol 2009, 10:1178-1184.
43. Jeon S.G., Kayama H., Ueda Y., Takahashi T., Asahara T., Tsuji H., Tsuji N.M., Kiyono H., Ma J.S., Kusu T., et al. Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon. PLoS Pathog 2012, 8:e1002714.
44. Kiyono H., McGhee J.R., Wannemuehler M.J., Michalek S.M. Lack of oral tolerance in C3H/HeJ mice. J Exp Med 1982, 155:605-610.
45. Tanaka K., Ishikawa H. Role of intestinal bacterial flora in oral tolerance induction. Histol Histopathol 2004, 19:907-914.
46. Ng S.C., Benjamin J.L., McCarthy N.E., Hedin C.R., Koutsoumpas A., Plamondon S., Price C.L., Hart A.L., Kamm M.A., Forbes A., et al. Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflamm Bowel Dis 2011, 17:2027-2037.
47. Louis P., Flint H.J. Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol Lett 2009, 294:1-8.
48. Ramirez-Farias C., Slezak K., Fuller Z., Duncan A., Holtrop G., Louis P. Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii. Br J Nutr 2009, 101:541-550.
49. Joly F., Mayeur C., Bruneau A., Noordine M.L., Meylheuc T., Langella P., Messing B., Duee P.H., Cherbuy C., Thomas M. Drastic changes in fecal and mucosa-associated microbiota in adult patients with short bowel syndrome. Biochimie 2010, 92:753-761.
50. Wang M., Molin G., Ahrne S., Adawi D., Jeppsson B. High proportions of proinflammatory bacteria on the colonic mucosa in a young patient with ulcerative colitis as revealed by cloning and sequencing of 16S rRNA genes. Dig Dis Sci 2007, 52:620-627.
51. Jia W., Whitehead R.N., Griffiths L., Dawson C., Waring R.H., Ramsden D.B., Hunter J.O., Cole J.A. Is the abundance of Faecalibacterium prausnitzii relevant to Crohn's disease?. FEMS Microbiol Lett 2010, 310:138-144.
52. Hansen R., Russell R.K., Reiff C., Louis P., McIntosh F., Berry S.H., Mukhopadhya I., Bisset W.M., Barclay A.R., Bishop J., et al. Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis. Am J Gastroenterol 2012, 107:1913-1922.
53. McLaughlin S.D., Walker A.W., Churcher C., Clark S.K., Tekkis P.P., Johnson M.W., Parkhill J., Ciclitira P.J., Dougan G., Nicholls R.J., et al. The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing. Ann Surg 2010, 252:90-98.
54. Vermeiren J., Van den Abbeele P., Laukens D., Vigsnaes L.K., De Vos M., Boon N., Van de Wiele T. Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin environment. FEMS Microbiol Ecol 2012, 79:685-696.
55. Kabeerdoss J., Sankaran V., Pugazhendhi S., Ramakrishna B.S. Clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: a case-control study in India. BMC Gastroenterol 2013, 13:20.
56. Martinez-Medina M., Aldeguer X., Gonzalez-Huix F., Acero D., Garcia-Gil L.J. Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis. Inflamm Bowel Dis 2006, 12:1136-1145.
57. Mondot S., Kang S., Furet J.P., Aguirre de Carcer D., McSweeney C., Morrison M., Marteau P., Dore J., Leclerc M. Highlighting new phylogenetic specificities of Crohn's disease microbiota. Inflamm Bowel Dis 2011, 17:185-192.
58. Joossens M., Huys G., Cnockaert M., De Preter V., Verbeke K., Rutgeerts P., Vandamme P., Vermeire S. Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives. Gut 2011, 60:631-637.
59. Fujimoto T., Imaeda H., Takahashi K., Kasumi E., Bamba S., Fujiyama Y., Andoh A. Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease. J Gastroenterol Hepatol 2013, 28:613-619.
60. Kang S., Denman S.E., Morrison M., Yu Z., Dore J., Leclerc M., McSweeney C.S. Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray. Inflamm Bowel Dis 2010, 16:2034-2042.
61. Benjamin J.L., Hedin C.R., Koutsoumpas A., Ng S.C., McCarthy N.E., Prescott N.J., Pessoa-Lopes P., Mathew C.G., Sanderson J., Hart A.L., et al. Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota. Inflamm Bowel Dis 2012, 18:1092-1100.
62. Li Q., Wang C., Tang C., Li N., Li J. Molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with Crohn's disease. PLoS ONE 2012, 7:e34939.