Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8

Science Translational Medicine

Volumn 10, Issue 423, 2018, Pages

  Kioon, Marie Dominique Ah ^a   Tripodo, Claudio ^b   Fernandez, David ^a   Kirou, Kyriakos A ^a   Spiera, Robert F ^a   Crow, Mary K ^a   Gordon, Jessica K ^a   Barrat, Franck J ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CHEMOKINE; CXCL4 CHEMOKINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE DELTA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; BLEOMYCIN; PF4 PROTEIN, HUMAN; THROMBOCYTE FACTOR 4;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE EXACERBATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOGENESIS; INFLAMMATION; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCLERODERMA; SIGNAL TRANSDUCTION; SKIN FIBROSIS; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; ANIMAL; DENDRITIC CELL; DISEASE MODEL; FIBROSIS; METABOLISM; PATHOLOGY; SKIN;

ANIMALS; BLEOMYCIN; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; HUMANS; INTERFERON-ALPHA; MALE; MICE; MIDDLE AGED; PLATELET FACTOR 4; SCLERODERMA, SYSTEMIC; SIGNAL TRANSDUCTION; SKIN; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 85040528918     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aam8458     Document Type: Article

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