PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

Nature

Volumn 552, Issue 7683, 2017, Pages 121-125

  Wartewig, Tim ^a,b   Kurgyis, Zsuzsanna ^a,b   Keppler, Selina ^a,b   Pechloff, Konstanze ^a,b,c   Hameister, Erik ^a,b   Öllinger, Rupert ^a,b   Maresch, Roman ^a,b   Buch, Thorsten ^d   Steiger, Katja ^b   Winter, Christof ^a,b,c   Rad, Roland ^a,b,c   Ruland, Jürgen ^a,b,c,e  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e German Center for Infection Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE C; T LYMPHOCYTE RECEPTOR; PDCD1 PROTEIN, HUMAN;

CELL; GENETIC ANALYSIS; IMMUNE RESPONSE; IMMUNOASSAY; RODENT; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL EXPANSION; GENE DELETION; GENE FREQUENCY; GENETIC SCREENING; GENOME; IN VIVO STUDY; LYMPHOMAGENESIS; MOUSE; MOUSE MODEL; MUTAGENESIS; NONHODGKIN LYMPHOMA; NONHUMAN; PDCD1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T CELL LYMPHOMA; TRANSPOSON; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; FEMALE; GENETICS; HAPLOINSUFFICIENCY; HUMAN; MALE; METABOLISM; MUTATION; PATHOLOGY; T LYMPHOCYTE; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOGENESIS; CELLS, CULTURED; FEMALE; GENES, TUMOR SUPPRESSOR; HAPLOINSUFFICIENCY; HUMANS; LYMPHOMA, T-CELL; MALE; MICE; MUTATION; PROGRAMMED CELL DEATH 1 RECEPTOR; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 85038873854     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature24649     Document Type: Article

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