Refrigeration-induced binding of von willebrand factor facilitates fast clearance of refrigerated platelets

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 37, Issue 12, 2017, Pages 2271-2279

  Chen, Wenchun ^a,b   Druzak, Samuel A ^a,b   Wang, Yingchun ^a,b   Josephson, Cassandra D ^a,b   Hoffmeister, Karin M ^c   Ware, Jerry ^d   Li, Renhao ^a,b  

^a CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BLOOD RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Phosphatidylserine; Platelet transfusion; Refrigeration; Temperature; Von Willebrand factor

Indexed keywords

CALCIUM ION; GLYCOPROTEIN IB ALPHA; PEPTIDE; PEPTIDE OS1; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; ADHESION RECEPTOR; PROTEIN BINDING; THROMBIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN UNFOLDING; REFRIGERATION; SIGNAL TRANSDUCTION; TEMPERATURE MEASUREMENT; THROMBOCYTE; WILD TYPE; ANIMAL; BINDING COMPETITION; BLOOD STORAGE; C57BL MOUSE; CHEMISTRY; COLD; DRUG EFFECTS; GENETICS; GENOTYPE; KNOCKOUT MOUSE; METABOLISM; PHENOTYPE; PROCEDURES; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; THROMBOCYTE ACTIVATION; THROMBOCYTE TRANSFUSION; TIME FACTOR; TRANSGENIC MOUSE;

ANIMALS; BINDING, COMPETITIVE; BLOOD PLATELETS; BLOOD PRESERVATION; COLD TEMPERATURE; GENOTYPE; HUMANS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PEPTIDES; PHENOTYPE; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET TRANSFUSION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN UNFOLDING; REFRIGERATION; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; VON WILLEBRAND FACTOR;

EID: 85038262852     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.117.310062     Document Type: Article

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