Conformational changes in the A1 domain of von Willebrand factor modulating the interaction with platelet glycoprotein Ibα

Journal of Biological Chemistry

Volumn 271, Issue 15, 1996, Pages 9046-9053

  Miyata, Shigeki ^a   Goto, Shinya ^a   Federici, Augusto B ^a,b   Ware, Jerry ^a   Ruggeri, Zaverio M ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DISULFIDE; GLYCOPROTEIN IB; MONOCLONAL ANTIBODY; VON WILLEBRAND FACTOR;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PH; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SHEAR STRESS; SITE DIRECTED MUTAGENESIS; THROMBOCYTE; THROMBOCYTE AGGREGATION; VON WILLEBRAND DISEASE;

ALKYLATION; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; CHO CELLS; CIRCULAR DICHROISM; CRICETINAE; DNA PRIMERS; HUMANS; IMMUNOLOGIC TECHNIQUES; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN; VON WILLEBRAND FACTOR;

EID: 0029882792     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.15.9046     Document Type: Article

References (49)

1. Ruggen, Z. M., and Ware, J. (1993) FASEB J. 7, 308-316
2. Fuster, W., Bowie, E J., Lewis, J. C., Fass, D. N., Owen, C. A. J , and Brown, A. L (1978) J. Clin. Invest, 61, 722-730
3. Nichols, T. C., Bellinger, D. A., Johnson, T. A , Lamb, M A., and Griggs, T. R. (1986) Circ. Res. 59, 15-26
4. Bellinger, D. A , Nichols, T. C., Read, M. S., Reddick, R. L., Lamb, M. A., Brinkhous, K. M., Evatt, B L., and Griggs, T. R. (1987) Proc Natl. Acad. Sci. U. S. A. 84, 8100-8104
5. Fajimura, Y., Titani, K , Holland, L. Z., Russell, S R., Roberts, J. R., Elder, J. H., Ruggeri, Z. M., and Zimmerman, T. S. (1986) J. Biol. Chem. 261, 381-385
6. Vicente, V., Houghten, R A , and Ruggeri, Z. M. (1990) J. Biol. Chem. 265, 274-280
7. Savage, B., Shattil, S. J., and Ruggeri, Z. M (1992) J Biol Chem. 267, 11300-11306
8. Alevriadou, B. R., Moake, J L , Turner, N. A., Ruggeri, Z. M., Folie, B J., Phillips, M. D., Schreiber, A. B., Hrinda, M. E., and McIntire, L. V (1993) Blood 81, 1263-1276
9. Shelton-Inloes, B. B , Titani, K., and Sadler, J. E. (1986) Biochemistry 25, 3164-3171
10. Andrews, R. K., German, J J , Booth, W. J., Corino, G. L , Castaldi, P. A., and Berndt, M. C. (1989) Biochemistry 28, 8326-8336
11. Mohri, H., Yoshioka, A , Zimmerman, T. S., and Ruggeri, Z. M. (1989) J Biol. Chem. 264, 17361-17367
12. Sugimoto, M., Ricca, G., Hrmda, M. E., Schreiber, A. E., Searfoss, G. H., Bottini, E., and Ruggeri, Z. M. (1991) Biochemistry 30, 5202-5209
13. Azuma, H., Dent, J. A , Sugimoto, M , Ruggeri, Z. M., and Ware, J. (1991) J. Biol. Chem. 266, 12342-12347
14. Azuma, H., Hayashi, T., Dent, J. A., Ruggeri, Z. M., and Ware, J. (1993) J Biol. Chem 268, 2821-2827
15. Howard, M A , and Firkin, B. G. (1971) Thromb. Haemostasis 26, 362-369
16. Scott, J P., Montgomery, R. R., and Retzinger. G. S. (1991) J. Biol Chem. 266, 8149-8155
17. Read, M. S., Smith, S. V., Lamb, M. A., and Brinkhous, K. M. (1989) Blood 74, 1031-1035
18. Sugimoto, M., Mohri, H., McClintock, R. A., and Ruggeri, Z. M. (1991) J. Biol Chem. 266, 18172-18178
19. Peterson, D M., Stathopoulos, N. A., Giorgio, T. D., Hellums, J. D., and Moake, J. L (1987) Blood 69, 625-628
20. Ware, J., Dent, J. A , Azuma, H., Sugimoto, M., Kyrle, P. A., Yoshioka, A., and Ruggeri, Z. M. (1991) Proc. Natl. Acad Sci U. S A. 88, 2946-2950
21. Pareti, F. I., Niiya, K., McPherson, J. M., and Ruggeri, Z. M (1987) J. Biol Chem 262, 13835-13841
22. Studier, F. W , and Moffatt, B. A. (1986) J. Mol. Biol. 189, 113-130
23. Rosenberg, A. H., Lade, B N., Chui, D. S., Lin, S. W., Dunn, J. J., and Studier, F. W. (1987) Gene (Amst.) 56, 125-135
24. Sugimoto, M., Dent, J., MeClintock, R , Ware, J , and Ruggeri, Z. M. (1993) J. Biol. Chem 268, 12185-12192
25. Prior, C. P., Chu, V., Cambou, B., Dent, J A., Ebert, B., Gore, R., Holt, J., Irish, T., Lee, J., Mitschelen, J , McClintock, R. A , Searfoss, G., Ricca, G A , Tarr, C , Weber, D , Ware, J. L., Ruggeri, Z. M , and Hrinda, M (1993) Biol Technology 11, 709-713
26. Ruggeri, Z. M , Pareti, F. I., Mannucci, P. M., Ciavarella, N., and Zimmerman, T. S (1980) N. Engl. J. Med. 302, 1047-1051
27. Ruggeri, Z. M., and Zimmerman, T. S. (1980) J. Clin. Invest. 65, 1318-1325
28. Kroner, P. A., Kluessendorf, M L., Scott, J. P., and Montgomery, R. R. (1992) Blood 79, 2048-2055
29. Ginsburg, D., and Sadler, J. E. (1993) Thromb. Haemostasis 69, 177-184
30. Rabinowitz, I., Tuley, E A., Mancuso, D. J., Randi, A. M., Firkin, B. G., Howard, M. A., and Sadler, J. B. (1992) Proc. Natl Acad. Sci. U S. A. 89, 9846-9849
31. Sadler, J. E. (1994) Thromb. Haemostasis 71, 520-525
32. Kunkel, T. A , Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-383
33. Mohri, H., Fujimura, Y., Shima, M , Yoshioka, A., Houghten, R A , Ruggeri, Z M., and Zimmerman, T. S. (1988) J. Biol. Chem. 263, 17901-17904
34. Handa, M , Titani, K., Holland, L Z., Roberts, J R., and Ruggeri, Z. M. (1986) J Biol. Chem 261, 12579-12585
35. Ey, P. L., Prowse, S. J , and Jenkin, C R. (1978) Immunochemistry 15, 429-436
36. Fraker, P J., and Speck, J. C. (1978) Biochem. Biophys. Res. Commun. 80, 849-857
37. Laemmh, U. K. (1970) Nature 227, 680-685
38. Goto, S , Salomon, D. R , Ikeda, Y., and Ruggeri, Z M. (1995) J. Biol Chem 270, 23352-21361
39. Ruggeri, Z M., De Marco, L., Gatti, L., Bader, R., and Montgomery, R. R (1983) J. Clin. Invest 72, 1-12
40. Corash, L. (1990) Blood Cells 160, 97-108
41. Ikeda, Y, Handa, M., Kawano, K., Kamata, T., Murata, M , Araki, Y., Anbo, H., Kawai, Y., Watanabe, K., Itagaki, I., Sakai, K., and Ruggeri, Z. M. (1991) J. Clin. Invest. 87, 1234-1240
42. Ptitsyn, O. B. (1987) J. Protein Chem 6, 273-293
43. Holmberg, L., Dent, J. A., Schneppenheim, R., Budde, U., Ware, J., and Ruggeri, Z. M. (1993) J. Clin. Invest. 91, 2169-2177
44. De Marco, L., Mazzucato, M , De Roia, D., Casonato, A., Federici, A. B., Girolami, A., and Ruggeri, Z. M. (1990) J. Clin. Invest. 86, 785-792
45. Cruz, M. A., Handin, R. I., and Wise, R. J. (1993) J. Biol. Chem. 268, 21238-21245
46. Matsushita, T., and Sadler, J. E (1995) J. Biol. Chem. 270, 13406-13414
47. Berndt, M. C , Ward, C. M., Booth, W J., Castaldi, P. A , Mazurov, A. V., and Andrews, R. K (1992) Biochemistry 31, 11144-11151
48. Girma, J. P, Takahashi, Y., Yoshioka, A., Diaz, J., and Meyer, D. (1990) Thromb. Haemostasis 64, 326-332
49. Titani, K., Kumar, S., Takio, K., Ericsson, L. H., Wade, R. D., Ashida, K., Walsh, K. A , Chopek, M. W , Sadler, J E., and Fujikawa, K. (1986) Biochemistry 25, 3171-3184