Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

Gastroenterology

Volumn 153, Issue 6, 2017, Pages 1504-1516.e2

  Nikolaus, Susanna ^a   Schulte, Berenice ^a   Al Massad, Natalie ^a   Thieme, Florian ^a   Schulte, Dominik M ^a   Bethge, Johannes ^a   Rehman, Ateequr ^b   Tran, Florian ^a,b   Aden, Konrad ^a,b   Häsler, Robert ^b   Moll, Natalie ^c   Schütze, Gregor ^c   Schwarz, Markus J ^c   Waetzig, Georg H ^d   Rosenstiel, Philip ^b   Krawczak, Michael ^b   Szymczak, Silke ^b   Schreiber, Stefan ^a,b  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d CONARIS Research Institute AG ^*  (Germany)

Author keywords

Amino Acid; Anti Inflammatory; Diet; Inflammation; Kynurenine

Indexed keywords

C REACTIVE PROTEIN; DNA 16S; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; INTERLEUKIN 22; KYNURENINE; MESSENGER RNA; QUINOLINIC ACID; SOLUTE CARRIER FAMILY 6 MEMBER 19; SOLUTE CARRIER PROTEIN; TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE; TRYPTOPHAN 2,3 DIOXYGENASE 2; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; AUTACOID; BIOLOGICAL MARKER; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; SLC6A19 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; AMINO ACID BLOOD LEVEL; AMPLICON; ARTICLE; COLITIS; COLON BIOPSY; CONTROLLED STUDY; CROHN DISEASE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES MICROFLORA; FEMALE; FOLLOW UP; GERMANY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INFLAMMATORY BOWEL DISEASE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION; TRYPTOPHAN METABOLISM; ULCERATIVE COLITIS; BIOTRANSFORMATION; BLOOD; CASE CONTROL STUDY; COLON; DEFICIENCY; FECES; GENETICS; INTESTINE FLORA; METABOLISM; MICROBIOLOGY; MIDDLE AGED; PREDICTIVE VALUE; PROGNOSIS; PROSPECTIVE STUDY; TIME FACTOR; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; BIOMARKERS; BIOTRANSFORMATION; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; COLITIS, ULCERATIVE; COLON; CROHN DISEASE; FECES; FEMALE; GASTROINTESTINAL MICROBIOME; GERMANY; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKINS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; QUINOLINIC ACID; TIME FACTORS; TRYPTOPHAN; TRYPTOPHAN OXYGENASE; YOUNG ADULT;

EID: 85035117631     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2017.08.028     Document Type: Article

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