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Volumn 757, Issue , 2015, Pages 21-27

Quinaldic acid inhibits proliferation of colon cancer HT-29 cells in vitro: Effects on signaling pathways

Author keywords

Chemical compounds studied in this article; Quinaldic acid (PubChem CID: 7124)

Indexed keywords

CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; QUINALDIC ACID; TRANSCRIPTION FACTOR; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE; QUINOLINE DERIVATIVE;

EID: 84926391847     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.02.053     Document Type: Article
Times cited : (14)

References (41)
  • 1
    • 23944515326 scopus 로고    scopus 로고
    • Intracellular signal transduction pathway proteins as targets for cancer therapy
    • A.A. Adjei, and M. Hidalgo Intracellular signal transduction pathway proteins as targets for cancer therapy J. Clin. Oncol. 23 2005 5386 5403
    • (2005) J. Clin. Oncol. , vol.23 , pp. 5386-5403
    • Adjei, A.A.1    Hidalgo, M.2
  • 2
    • 0001752768 scopus 로고    scopus 로고
    • The Cambridge structural database: A quarter of a million crystal structures and rising
    • F.H. Allen The Cambridge structural database: a quarter of a million crystal structures and rising Acta Crystallogr. B 58 2002 380 388
    • (2002) Acta Crystallogr. B , vol.58 , pp. 380-388
    • Allen, F.H.1
  • 3
    • 77956165220 scopus 로고    scopus 로고
    • Caught in the Akt: Regulation of Wnt signaling in the intestine
    • E.C. Anderson, and M.H. Wong Caught in the Akt: regulation of Wnt signaling in the intestine Gastroenterology 139 2010 718 722
    • (2010) Gastroenterology , vol.139 , pp. 718-722
    • Anderson, E.C.1    Wong, M.H.2
  • 4
    • 84926347883 scopus 로고
    • Estimation of zinc in aluminum alloys by means of quinaldinic acid
    • J.H. Bartram, and P.J. Kent Estimation of zinc in aluminum alloys by means of quinaldinic acid Metallurgia 33 1946 179 181
    • (1946) Metallurgia , vol.33 , pp. 179-181
    • Bartram, J.H.1    Kent, P.J.2
  • 5
    • 23944526062 scopus 로고    scopus 로고
    • Activation of AKT kinases in cancer: Implications for therapeutic targeting
    • A. Bellacosa, C.C. Kumar, A. Di Cristofano, and J.R. Testa Activation of AKT kinases in cancer: implications for therapeutic targeting Adv. Cancer Res. 94 2005 29 86
    • (2005) Adv. Cancer Res. , vol.94 , pp. 29-86
    • Bellacosa, A.1    Kumar, C.C.2    Di Cristofano, A.3    Testa, J.R.4
  • 6
    • 0017138410 scopus 로고
    • Mutagenic activity of Trp metabolites produced by rat intestinal microflora
    • J.P. Bowden, K.T. Chung, and A. Andrews Mutagenic activity of Trp metabolites produced by rat intestinal microflora J. Natl. Cancer Inst. 57 1976 921 924
    • (1976) J. Natl. Cancer Inst. , vol.57 , pp. 921-924
    • Bowden, J.P.1    Chung, K.T.2    Andrews, A.3
  • 7
    • 0347381537 scopus 로고
    • Quantitative studies on metabolites of tryptophan in the urine of the dog, cat, rat, and man
    • R.R. Brown, and J.M. Price Quantitative studies on metabolites of tryptophan in the urine of the dog, cat, rat, and man J. Biol. Chem. 219 1956 985 997
    • (1956) J. Biol. Chem. , vol.219 , pp. 985-997
    • Brown, R.R.1    Price, J.M.2
  • 8
    • 0015092005 scopus 로고
    • The role of urinary tryptophan metabolites in the etiology of bladder cancer
    • G.T. Bryan The role of urinary tryptophan metabolites in the etiology of bladder cancer Am. J. Clin. Nutr. 24 1971 841 847
    • (1971) Am. J. Clin. Nutr. , vol.24 , pp. 841-847
    • Bryan, G.T.1
  • 9
    • 44349111717 scopus 로고    scopus 로고
    • Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: Is PTEN loss predictor of local recurrence?
    • T. Colakoglu, S. Yildirim, F. Kayaselcuk, T.Z. Nursal, A. Ezer, T. Noyan, H. Karakayali, and M. Haberal Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local recurrence? Am. J. Surg. 195 2008 719 725
    • (2008) Am. J. Surg. , vol.195 , pp. 719-725
    • Colakoglu, T.1    Yildirim, S.2    Kayaselcuk, F.3    Nursal, T.Z.4    Ezer, A.5    Noyan, T.6    Karakayali, H.7    Haberal, M.8
  • 11
    • 0017883532 scopus 로고
    • Synthesis and metabolism of l-kynurenine in rat brain
    • E.M. Gal, and A.D. Sherman Synthesis and metabolism of l-kynurenine in rat brain J. Neurochem. 30 1978 607 613
    • (1978) J. Neurochem. , vol.30 , pp. 607-613
    • Gal, E.M.1    Sherman, A.D.2
  • 12
    • 51449119250 scopus 로고    scopus 로고
    • Therapeutic strategies for inhibiting oncogenic BRAF signaling
    • E. Halilovic, and D.B. Solit Therapeutic strategies for inhibiting oncogenic BRAF signaling Curr. Opin. Pharmacol. 8 2008 419 426
    • (2008) Curr. Opin. Pharmacol. , vol.8 , pp. 419-426
    • Halilovic, E.1    Solit, D.B.2
  • 13
    • 0014690828 scopus 로고
    • Mode of action of hypoglycemic agents. I. Inhibition of gluconeogenesis by quinaldic acid and 5-methoxyindole-2-carboxylic acid
    • R.L. Hanson, P.D. Ray, P. Walter, and H.A. Lardy Mode of action of hypoglycemic agents. I. Inhibition of gluconeogenesis by quinaldic acid and 5-methoxyindole-2-carboxylic acid J. Biol. Chem. 244 1969 4351 4359
    • (1969) J. Biol. Chem. , vol.244 , pp. 4351-4359
    • Hanson, R.L.1    Ray, P.D.2    Walter, P.3    Lardy, H.A.4
  • 14
    • 0037096804 scopus 로고    scopus 로고
    • Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma
    • N. Itoh, S. Semba, M. Ito, H. Takeda, S. Kawata, and M. Yamakawa Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma Cancer 94 2002 127 134
    • (2002) Cancer , vol.94 , pp. 127-134
    • Itoh, N.1    Semba, S.2    Ito, M.3    Takeda, H.4    Kawata, S.5    Yamakawa, M.6
  • 15
    • 73049167444 scopus 로고
    • The metabolism of quinaldic acid
    • M. Kaihara, and J.M. Price The metabolism of quinaldic acid J. Biol. Chem. 237 1962 1727 1729
    • (1962) J. Biol. Chem. , vol.237 , pp. 1727-1729
    • Kaihara, M.1    Price, J.M.2
  • 19
    • 77950364793 scopus 로고    scopus 로고
    • Growth inhibiting activity of quinaldic acid isolated from Ephedra pachyclada against intestinal bacteria
    • C.H. Lee, and H.S. Lee Growth inhibiting activity of quinaldic acid isolated from Ephedra pachyclada against intestinal bacteria J. Korean Soc. Appl. Biol. Chem. 52 2009 331 335
    • (2009) J. Korean Soc. Appl. Biol. Chem. , vol.52 , pp. 331-335
    • Lee, C.H.1    Lee, H.S.2
  • 20
    • 84951384024 scopus 로고
    • A simplified method of evaluating dose-effect experiments
    • J.T. Litchfield, and F.A. Wilcoxon A simplified method of evaluating dose-effect experiments J. Pharmacol. Exp. Ther. 96 1949 99 113
    • (1949) J. Pharmacol. Exp. Ther. , vol.96 , pp. 99-113
    • Litchfield, J.T.1    Wilcoxon, F.A.2
  • 21
    • 36248987708 scopus 로고    scopus 로고
    • Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin-induced cell death
    • S. Maddika, G.H. Bay, T.J. Kroczak, S.R. Ande, S. Maddika, E. Wiechec, S.B. Gibson, and M. Los Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin-induced cell death Cell Prolif. 40 2007 835 848
    • (2007) Cell Prolif. , vol.40 , pp. 835-848
    • Maddika, S.1    Bay, G.H.2    Kroczak, T.J.3    Ande, S.R.4    Maddika, S.5    Wiechec, E.6    Gibson, S.B.7    Los, M.8
  • 22
    • 61749088475 scopus 로고    scopus 로고
    • Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity
    • S. Maddika, S. Panigrahi, E. Wiechec, S. Wesselborg, U. Fischer, K. Schulze-Osthoff, and M. Los Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity Mol. Cell Biol. 29 2009 1235 1248
    • (2009) Mol. Cell Biol. , vol.29 , pp. 1235-1248
    • Maddika, S.1    Panigrahi, S.2    Wiechec, E.3    Wesselborg, S.4    Fischer, U.5    Schulze-Osthoff, K.6    Los, M.7
  • 23
    • 65949119310 scopus 로고    scopus 로고
    • How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
    • Y. Mebratu, and Y. Tesfaigzi How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle 8 2009 1168 1175
    • (2009) Cell Cycle , vol.8 , pp. 1168-1175
    • Mebratu, Y.1    Tesfaigzi, Y.2
  • 24
    • 79953702532 scopus 로고    scopus 로고
    • Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations
    • H.A. Mutsaers, L.P. van den Heuvel, L.H. Ringens, A.C. Dankers, F.G. Russel, J.F. Wetzels, J.G. Hoenderop, and R. Masereeuw Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations PLoS One 6 4 2011 e18438
    • (2011) PLoS One , vol.6 , Issue.4 , pp. e18438
    • Mutsaers, H.A.1    Van Den Heuvel, L.P.2    Ringens, L.H.3    Dankers, A.C.4    Russel, F.G.5    Wetzels, J.F.6    Hoenderop, J.G.7    Masereeuw, R.8
  • 25
    • 0018252076 scopus 로고
    • Inhibition by kynurenine metabolites of proinsulin synthesis in isolated pancreatic islets
    • Y. Noto, and H. Okamoto Inhibition by kynurenine metabolites of proinsulin synthesis in isolated pancreatic islets Acta Diabetol. Lat. 15 1978 273 282
    • (1978) Acta Diabetol. Lat. , vol.15 , pp. 273-282
    • Noto, Y.1    Okamoto, H.2
  • 26
    • 0016137888 scopus 로고
    • Inhibitory effect of quinaldic acid on glucose-induced insulin release from isolated Langerhans islets of the rat
    • H. Okamoto, S. Miyamoto, H. Mabuchi, and R. Takeda Inhibitory effect of quinaldic acid on glucose-induced insulin release from isolated Langerhans islets of the rat Biochem. Biophys. Res. Commun. 59 1974 623 629
    • (1974) Biochem. Biophys. Res. Commun. , vol.59 , pp. 623-629
    • Okamoto, H.1    Miyamoto, S.2    Mabuchi, H.3    Takeda, R.4
  • 34
    • 0014107133 scopus 로고
    • Influence of l-tryptophan and its metabolites on gluconeogenesis in the isolated, perfused liver
    • C.M. Veneziale, P. Walter, N. Kneer, and H.A. Lardy Influence of l-tryptophan and its metabolites on gluconeogenesis in the isolated, perfused liver Biochemistry 6 1967 2129 2138
    • (1967) Biochemistry , vol.6 , pp. 2129-2138
    • Veneziale, C.M.1    Walter, P.2    Kneer, N.3    Lardy, H.A.4
  • 37
    • 84930741113 scopus 로고    scopus 로고
    • Kynurenic acid inhibits colon cancer proliferation in vitro: Effects on signaling pathways
    • K. Walczak, W.A. Turski, and G. Rajtar Kynurenic acid inhibits colon cancer proliferation in vitro: effects on signaling pathways Amino Acids 46 2014 2393 2401
    • (2014) Amino Acids , vol.46 , pp. 2393-2401
    • Walczak, K.1    Turski, W.A.2    Rajtar, G.3
  • 38
    • 84866079666 scopus 로고    scopus 로고
    • Kynurenic acid enhances expression of p21 Waf1/Cip1 in colon cancer HT-29 cells
    • K. Walczak, W.A. Turski, and W. Rzeski Kynurenic acid enhances expression of p21 Waf1/Cip1 in colon cancer HT-29 cells Pharmacol. Rep. 64 2012 745 750
    • (2012) Pharmacol. Rep. , vol.64 , pp. 745-750
    • Walczak, K.1    Turski, W.A.2    Rzeski, W.3
  • 39
    • 84867577438 scopus 로고    scopus 로고
    • Kynurenic acid in human renal cell carcinoma: Its antiproliferative and antimigrative action on Caki-2 cells
    • K. Walczak, M. Zurawska, J. Kis, R. Starownik, W. Zgrajka, K. Bar, W.A. Turski, and W. Rzeski Kynurenic acid in human renal cell carcinoma: its antiproliferative and antimigrative action on Caki-2 cells Amino Acids 43 2012 1663 1670
    • (2012) Amino Acids , vol.43 , pp. 1663-1670
    • Walczak, K.1    Zurawska, M.2    Kis, J.3    Starownik, R.4    Zgrajka, W.5    Bar, K.6    Turski, W.A.7    Rzeski, W.8
  • 40


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.