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Volumn 9, Issue 12, 2014, Pages

IDO1 and IDO2 non-synonymous gene variants: Correlation with Crohn's disease risk and clinical phenotype

Author keywords

[No Author keywords available]

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; INDOLEAMINE 2,3 DIOXYGENASE 2; KYNURENINE; TRYPTOPHAN; UNCLASSIFIED DRUG; INDOLEAMINE 2,3-DIOXYGENASE 1, HUMAN; INDOLEAMINE 2,3-DIOXYGENASE 2, HUMAN;

EID: 84919935141     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115848     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 84858386087 scopus 로고    scopus 로고
    • Biomarkers in inflammatory bowel disease: Current practices and recent advances
    • Iskandar HN, Ciorba MA (2012) Biomarkers in inflammatory bowel disease: current practices and recent advances. Transl Res 159: 313-325.
    • (2012) Transl Res , vol.159 , pp. 313-325
    • Iskandar, H.N.1    Ciorba, M.A.2
  • 2
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier RJ, Podolsky DK (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427-434.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 3
    • 84868336049 scopus 로고    scopus 로고
    • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
    • Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, et al. (2012) Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 491: 119-124.
    • (2012) Nature , vol.491 , pp. 119-124
    • Jostins, L.1    Ripke, S.2    Weersma, R.K.3    Duerr, R.H.4    McGovern, D.P.5
  • 4
    • 79955566359 scopus 로고    scopus 로고
    • Recent insights into the genetics of inflammatory bowel disease
    • Cho JH, Brant SR (2011) Recent insights into the genetics of inflammatory bowel disease. Gastroenterology 140: 1704-1712.
    • (2011) Gastroenterology , vol.140 , pp. 1704-1712
    • Cho, J.H.1    Brant, S.R.2
  • 5
    • 84875261622 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and metabolic control of immune responses
    • Munn DH, Mellor AL (2013) Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol 34: 137-143.
    • (2013) Trends Immunol , vol.34 , pp. 137-143
    • Munn, D.H.1    Mellor, A.L.2
  • 6
    • 84862174198 scopus 로고    scopus 로고
    • Serum analysis of tryptophan catabolism pathway: Correlation with Crohn's disease activity
    • Gupta NK, Thaker AI, Kanuri N, Riehl TE, Rowley CW, et al. (2012) Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity. Inflamm Bowel Dis 18: 1214-1220.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1214-1220
    • Gupta, N.K.1    Thaker, A.I.2    Kanuri, N.3    Riehl, T.E.4    Rowley, C.W.5
  • 7
    • 84873413184 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase in intestinal disease
    • Ciorba MA (2013) Indoleamine 2,3 dioxygenase in intestinal disease. Curr Opin Gastroenterol 29: 146-152.
    • (2013) Curr Opin Gastroenterol , vol.29 , pp. 146-152
    • Ciorba, M.A.1
  • 8
    • 0345490963 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice
    • Gurtner GJ, Newberry RD, Schloemann SR, McDonald KG, Stenson WF (2003) Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. Gastroenterology 125: 1762-1773.
    • (2003) Gastroenterology , vol.125 , pp. 1762-1773
    • Gurtner, G.J.1    Newberry, R.D.2    Schloemann, S.R.3    McDonald, K.G.4    Stenson, W.F.5
  • 9
    • 77951635953 scopus 로고    scopus 로고
    • Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis
    • Ciorba MA, Bettonville EE, McDonald KG, Metz R, Prendergast GC, et al. (2010) Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis. J Immunol 184: 3907-3916.
    • (2010) J Immunol , vol.184 , pp. 3907-3916
    • Ciorba, M.A.1    Bettonville, E.E.2    McDonald, K.G.3    Metz, R.4    Prendergast, G.C.5
  • 10
    • 84880630193 scopus 로고    scopus 로고
    • IDO1 metabolites activate beta-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice
    • Thaker AI, Rao MS, Bishnupuri KS, Kerr TA, Foster L, et al. (2013) IDO1 metabolites activate beta-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice. Gastroenterology 145: 416-425 e411-414.
    • (2013) Gastroenterology , vol.145
    • Thaker, A.I.1    Rao, M.S.2    Bishnupuri, K.S.3    Kerr, T.A.4    Foster, L.5
  • 11
    • 54849418903 scopus 로고    scopus 로고
    • IDO1 and IDO2 are expressed in human tumors: Levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
    • Lob S, Konigsrainer A, Zieker D, Brucher BL, Rammensee HG, et al. (2009) IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism. Cancer Immunol Immunother 58: 153-157.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 153-157
    • Lob, S.1    Konigsrainer, A.2    Zieker, D.3    Brucher, B.L.4    Rammensee, H.G.5
  • 14
    • 70149116670 scopus 로고    scopus 로고
    • Identification of genetic variants in the human indoleamine 2,3-dioxygenase (IDO1) gene, which have altered enzyme activity
    • Arefayene M, Philips S, Cao D, Mamidipalli S, Desta Z, et al. (2009) Identification of genetic variants in the human indoleamine 2,3-dioxygenase (IDO1) gene, which have altered enzyme activity. Pharmacogenet Genomics 19: 464-476.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 464-476
    • Arefayene, M.1    Philips, S.2    Cao, D.3    Mamidipalli, S.4    Desta, Z.5
  • 15
    • 80052692788 scopus 로고    scopus 로고
    • Influence of Crohn's disease risk alleles and smoking on disease location
    • Chen H, Lee A, Bowcock A, Zhu W, Li E, et al. (2011) Influence of Crohn's disease risk alleles and smoking on disease location. Dis Colon Rectum 54: 1020-1025.
    • (2011) Dis Colon Rectum , vol.54 , pp. 1020-1025
    • Chen, H.1    Lee, A.2    Bowcock, A.3    Zhu, W.4    Li, E.5
  • 16
    • 33646778482 scopus 로고    scopus 로고
    • The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications
    • Satsangi J, Silverberg MS, Vermeire S, Colombel JF (2006) The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 55: 749-753.
    • (2006) Gut , vol.55 , pp. 749-753
    • Satsangi, J.1    Silverberg, M.S.2    Vermeire, S.3    Colombel, J.F.4
  • 17
    • 84861012132 scopus 로고    scopus 로고
    • An ileal Crohn's disease gene signature based on whole human genome expression profiles of disease unaffected ileal mucosal biopsies
    • Zhang T, Song B, Zhu W, Xu X, Gong QQ, et al. (2012) An ileal Crohn's disease gene signature based on whole human genome expression profiles of disease unaffected ileal mucosal biopsies. PLoS One 7: e37139.
    • (2012) PLoS One , vol.7 , pp. e37139
    • Zhang, T.1    Song, B.2    Zhu, W.3    Xu, X.4    Gong, Q.Q.5
  • 19
    • 0031451315 scopus 로고    scopus 로고
    • Simultaneous measurement of serum tryptophan and kynurenine by HPLC
    • Widner B, Werner ER, Schennach H, Wachter H, Fuchs D (1997) Simultaneous measurement of serum tryptophan and kynurenine by HPLC. Clin Chem 43: 2424-2426.
    • (1997) Clin Chem , vol.43 , pp. 2424-2426
    • Widner, B.1    Werner, E.R.2    Schennach, H.3    Wachter, H.4    Fuchs, D.5
  • 21
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society Series B: 289-300.
    • (1995) Journal of the Royal Statistical Society Series B , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 22
    • 20544469356 scopus 로고    scopus 로고
    • TNFalpha and IL10 SNPs act together to predict disease behaviour in Crohn's disease
    • Fowler EV, Eri R, Hume G, Johnstone S, Pandeya N, et al. (2005) TNFalpha and IL10 SNPs act together to predict disease behaviour in Crohn's disease. J Med Genet 42: 523-528.
    • (2005) J Med Genet , vol.42 , pp. 523-528
    • Fowler, E.V.1    Eri, R.2    Hume, G.3    Johnstone, S.4    Pandeya, N.5
  • 23
    • 34547643025 scopus 로고    scopus 로고
    • Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    • Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, et al. (2007) Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res 67: 7082-7087.
    • (2007) Cancer Res , vol.67 , pp. 7082-7087
    • Metz, R.1    Duhadaway, J.B.2    Kamasani, U.3    Laury-Kleintop, L.4    Muller, A.J.5
  • 24
    • 79957963254 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases
    • Prendergast GC, Chang MY, Mandik-Nayak L, Metz R, Muller AJ (2011) Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases. Curr Med Chem 18: 2257-2262.
    • (2011) Curr Med Chem , vol.18 , pp. 2257-2262
    • Prendergast, G.C.1    Chang, M.Y.2    Mandik-Nayak, L.3    Metz, R.4    Muller, A.J.5
  • 25
    • 84885658881 scopus 로고    scopus 로고
    • Recent advances in inflammatory bowel disease: Mucosal immune cells in intestinal inflammation
    • Cader MZ, Kaser A (2013) Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation. Gut 62: 1653-1664.
    • (2013) Gut , vol.62 , pp. 1653-1664
    • Cader, M.Z.1    Kaser, A.2
  • 26
    • 84872015298 scopus 로고    scopus 로고
    • Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2: The Absence of IDO1 Upregulates IDO2 Expression in the Epididymis
    • Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, et al. (2012) Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2: The Absence of IDO1 Upregulates IDO2 Expression in the Epididymis. J Histochem Cytochem.
    • (2012) J Histochem Cytochem
    • Fukunaga, M.1    Yamamoto, Y.2    Kawasoe, M.3    Arioka, Y.4    Murakami, Y.5
  • 27
    • 84896516675 scopus 로고    scopus 로고
    • IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation
    • Epub ahead of print
    • Metz R, Smith C, Duhadaway JB, Chandler P, Baban B, et al. (2014 [Epub ahead of print]) IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. Int Immunol.
    • (2014) Int Immunol
    • Metz, R.1    Smith, C.2    Duhadaway, J.B.3    Chandler, P.4    Baban, B.5
  • 28
  • 29
    • 33747119866 scopus 로고    scopus 로고
    • 4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms
    • Choi BK, Asai T, Vinay DS, Kim YH, Kwon BS (2006) 4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms. Cytokine 34: 233-242.
    • (2006) Cytokine , vol.34 , pp. 233-242
    • Choi, B.K.1    Asai, T.2    Vinay, D.S.3    Kim, Y.H.4    Kwon, B.S.5
  • 30
    • 47249131189 scopus 로고    scopus 로고
    • Inflamed intestinal mucosa features a specific epithelial expression pattern of indoleamine 2,3-dioxygenase
    • Ferdinande L, Demetter P, Perez-Novo C, Waeytens A, Taildeman J, et al. (2008) Inflamed intestinal mucosa features a specific epithelial expression pattern of indoleamine 2,3-dioxygenase. Int J Immunopathol Pharmacol 21: 289-295.
    • (2008) Int J Immunopathol Pharmacol , vol.21 , pp. 289-295
    • Ferdinande, L.1    Demetter, P.2    Perez-Novo, C.3    Waeytens, A.4    Taildeman, J.5
  • 32
    • 84863775017 scopus 로고    scopus 로고
    • Posttranslational modification of indoleamine 2,3-dioxygenase
    • Fujigaki H, Seishima M, Saito K (2012) Posttranslational modification of indoleamine 2,3-dioxygenase. Anal Bioanal Chem 403: 1777-1782.
    • (2012) Anal Bioanal Chem , vol.403 , pp. 1777-1782
    • Fujigaki, H.1    Seishima, M.2    Saito, K.3
  • 33
    • 0038256114 scopus 로고    scopus 로고
    • Available
    • Genetic Power Calculator. Available: http://pngu.mgh.harvard.edu/~purcell/gpc/#cc-ins.Harvard.
    • Genetic Power Calculator
  • 35
    • 84872617225 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase gene polymorphisms correlate with CD8+ Treg impairment in systemic sclerosis
    • Tardito S, Negrini S, Conteduca G, Ferrera F, Parodi A, et al. (2013) Indoleamine 2,3 dioxygenase gene polymorphisms correlate with CD8+ Treg impairment in systemic sclerosis. Hum Immunol 74: 166-169.
    • (2013) Hum Immunol , vol.74 , pp. 166-169
    • Tardito, S.1    Negrini, S.2    Conteduca, G.3    Ferrera, F.4    Parodi, A.5
  • 36
    • 64949113986 scopus 로고    scopus 로고
    • Genotyping and expression analysis of IDO2 in human pancreatic cancer: A novel, active target
    • discussion 787-789.
    • Witkiewicz AK, Costantino CL, Metz R, Muller AJ, Prendergast GC, et al. (2009) Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target. J Am Coll Surg 208: 781-787; discussion 787-789.
    • (2009) J Am Coll Surg , vol.208 , pp. 781-787
    • Witkiewicz, A.K.1    Costantino, C.L.2    Metz, R.3    Muller, A.J.4    Prendergast, G.C.5
  • 37
    • 84857815702 scopus 로고    scopus 로고
    • Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder
    • Cutler JA, Rush AJ, McMahon FJ, Laje G (2012) Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder. J Psychopharmacol 26: 360-367.
    • (2012) J Psychopharmacol , vol.26 , pp. 360-367
    • Cutler, J.A.1    Rush, A.J.2    McMahon, F.J.3    Laje, G.4
  • 38
    • 84895900553 scopus 로고    scopus 로고
    • Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the oral inhibitor of indoleamine 2,3-dioxygenase (IDO1) INCB024360 in patients (pts) with advanced malignancies
    • Abstract
    • Beatty GL, O'Dwyer PJ, Clark J, Shi JG, Newton RC, et al. (2013) Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the oral inhibitor of indoleamine 2,3-dioxygenase (IDO1) INCB024360 in patients (pts) with advanced malignancies. J Clin Oncol 31 (Abstract 3025).
    • (2013) J Clin Oncol , vol.31
    • Beatty, G.L.1    O'Dwyer, P.J.2    Clark, J.3    Shi, J.G.4    Newton, R.C.5


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