Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells

Biochimie

Volumn 145, Issue , 2018, Pages 53-62

  Civit, Laia ^a   Taghdisi, Seyed Mohammad ^a,f   Jonczyk, Anna ^a   Haßel, Silvana K ^a   Gröber, Carsten ^b   Blank, Michael ^b   Stunden, H James ^c   Beyer, Marc ^a,d   Schultze, Joachim ^a   Latz, Eicke ^c,d,e   Mayer, Günter ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Am Klopferspitz 19a   (Germany)

^c UNIVERSITY HOSPITAL BONN   (Germany)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Broad spectrum aptamers; Cell SELEX; DNA aptamers; High throughput sequencing; Screening methods

Indexed keywords

APTAMER; DNA; OLIGONUCLEOTIDE; ANTINEOPLASTIC AGENT;

A-549 CELL LINE; ARTICLE; BINDING AFFINITY; BREAST CANCER CELL LINE; CONTROLLED STUDY; DNA LIBRARY; EVALUATION STUDY; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IN VITRO SELECTION; INTERMETHOD COMPARISON; MCF-7 CELL LINE; MOLECULAR INTERACTION; NCI-H460 CELL LINE; NEXT GENERATION SEQUENCING; RAMOS CELL LINE; SANGER SEQUENCING; SOLID MALIGNANT NEOPLASM; THP-1 CELL LINE; BREAST TUMOR; CHEMISTRY; DRUG SCREENING; FEMALE; METABOLISM; PATHOLOGY; PROCEDURES; SYNTHESIS; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

A549 CELLS; ANTINEOPLASTIC AGENTS; APTAMERS, NUCLEOTIDE; BREAST NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MCF-7 CELLS; SELEX APTAMER TECHNIQUE;

EID: 85035048301     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2017.10.007     Document Type: Article

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