Identification of an aptamer through whole cell-SELEX for targeting high metastatic liver cancers

Oncotarget

Volumn 7, Issue 7, 2016, Pages 8282-8294

  Rong, Yuan ^a   Chen, Hao ^a   Zhou, Xue Feng ^a   Yin, Chang Qing ^a   Wang, Bi Cheng ^a   Peng, Chun Wei ^a   Liu, Shao Ping ^b   Wang, Fu Bing ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b Hubei Cancer Clinical Study Center   (China)

Author keywords

Aptamer; Cell SELEX; Hepatocellular carcinoma; Invasion; Migration

Indexed keywords

APTAMER; CYTOKERATIN 19; LY 1 APTAMER; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; VIMENTIN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CELL INVASION; CELL MIGRATION; CELL SUBPOPULATION; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; LIVER CELL CARCINOMA; LUNG METASTASIS; MALE; METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CARCINOMA, HEPATOCELLULAR; CELL MOTION; CELL PROLIFERATION; DRUG SCREENING; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; LIVER NEOPLASMS; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APTAMERS, NUCLEOTIDE; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; CELL PROLIFERATION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SELEX APTAMER TECHNIQUE; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84958781074     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6988     Document Type: Article

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