Artemether Does Not Turn α Cells into β Cells

Cell Metabolism

Volumn 27, Issue 1, 2018, Pages 218-225.e4

  van der Meulen, Talitha ^a   Lee, Sharon ^a   Noordeloos, Els ^a   Donaldson, Cynthia J ^b   Adams, Michael W ^a   Noguchi, Glyn M ^a   Mawla, Alex M ^a   Huising, Mark O ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

artemether; artemisinins; dedifferentiation; diabetes; GCaMP6; maturation; neogenesis; pancreatic islet; transdifferentiation

Indexed keywords

ARTEMETHER; CALCIUM; GLUCOSE; INSULIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ARX; UNCLASSIFIED DRUG; ARX PROTEIN, MOUSE; HOMEODOMAIN PROTEIN;

ARTICLE; CELL TRANSDIFFERENTIATION; DIABETES MELLITUS; DRUG MECHANISM; GENE; GENE EXPRESSION; GLUCOSE TRANSPORT; INS2 GENE; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DEATH; DRUG EFFECT; METABOLISM;

ANIMALS; ARTEMETHER; CALCIUM; CELL DEATH; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; GLUCAGON-SECRETING CELLS; GLUCOSE; HOMEODOMAIN PROTEINS; INSULIN; INSULIN SECRETION; INSULIN-SECRETING CELLS; MICE, INBRED C57BL; TRANSCRIPTION FACTORS;

EID: 85034967038     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2017.10.002     Document Type: Article

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