메뉴 건너뛰기




Volumn 49, Issue 3, 2017, Pages

Metabolomics analysis identifies different metabotypes of asthma severity

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID DERIVATIVE; CORTISONE; HYDROCORTISONE; HYDROXYPROLINE; N OLEOYLETHANOLAMINE; N PALMITOYLTAURINE; PIPECOLIC ACID; PRASTERONE SULFATE; PROLYLHYDROXYPROLINE; TAURINE DERIVATIVE; UNCLASSIFIED DRUG; CORTICOSTEROID;

EID: 85034765323     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.01740-2016     Document Type: Article
Times cited : (149)

References (46)
  • 1
  • 3
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex. Heterogeneous disease
    • Anderson GP. Endotyping asthma: new insights into key pathogenic mechanisms in a complex. heterogeneous disease. Lancet 2008; 372: 1107–1119.
    • (2008) Lancet , vol.372 , pp. 1107-1119
    • Anderson, G.P.1
  • 4
    • 84893513577 scopus 로고    scopus 로고
    • International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
    • Chung KF, Wenzel SE, Brozek JL, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J 2014; 43: 343–373.
    • (2014) Eur Respir J , vol.43 , pp. 343-373
    • Chung, K.F.1    Wenzel, S.E.2    Brozek, J.L.3
  • 5
    • 78650315006 scopus 로고    scopus 로고
    • Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy
    • Dunn WB, Broadhurst DI, Atherton HJ, et al. Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem Soc Rev 2011; 40: 387–426.
    • (2011) Chem Soc Rev , vol.40 , pp. 387-426
    • Dunn, W.B.1    Broadhurst, D.I.2    Atherton, H.J.3
  • 6
    • 33846240326 scopus 로고    scopus 로고
    • Statistical strategies for avoiding false discoveries in metabolomics and related experiments
    • Broadhurst DI, Kell DB. Statistical strategies for avoiding false discoveries in metabolomics and related experiments. Metabolomics 2006; 2: 171–196.
    • (2006) Metabolomics , vol.2 , pp. 171-196
    • Broadhurst, D.I.1    Kell, D.B.2
  • 7
    • 1642300806 scopus 로고    scopus 로고
    • Ten categories of statistical errors: A guide for research in endocrinology and metabolism
    • Holmes TH. Ten categories of statistical errors: a guide for research in endocrinology and metabolism. Am J Physiol Endocrinol Metab 2004; 286: E495–E501.
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , pp. E495-E501
    • Holmes, T.H.1
  • 8
    • 84875512899 scopus 로고    scopus 로고
    • Serum metabolomics reveals pathways and biomarkers associated with asthma pathogenesis
    • Jung J, Kim SH, Lee HS, et al. Serum metabolomics reveals pathways and biomarkers associated with asthma pathogenesis. Clin Exp Allergy 2013; 43: 425–433.
    • (2013) Clin Exp Allergy , vol.43 , pp. 425-433
    • Jung, J.1    Kim, S.H.2    Lee, H.S.3
  • 9
    • 84876678696 scopus 로고    scopus 로고
    • Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma
    • Ried JS, Baurecht H, Stuckler F, et al. Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma. Allergy 2013; 68: 629–636.
    • (2013) Allergy , vol.68 , pp. 629-636
    • Ried, J.S.1    Baurecht, H.2    Stuckler, F.3
  • 10
    • 84891724066 scopus 로고    scopus 로고
    • Urinary metabolomic changes as a predictive biomarker of asthma exacerbation
    • Loureiro CC, Duarte IF, Gomes J, et al. Urinary metabolomic changes as a predictive biomarker of asthma exacerbation. J Allergy Clin Immunol 2014; 133: 261–263.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 261-263
    • Loureiro, C.C.1    Duarte, I.F.2    Gomes, J.3
  • 11
    • 79952309777 scopus 로고    scopus 로고
    • Metabolomic profiling of asthma: Diagnostic utility of urine nuclear magnetic resonance spectroscopy
    • Saude EJ, Skappak CD, Regush S, et al. Metabolomic profiling of asthma: diagnostic utility of urine nuclear magnetic resonance spectroscopy. J Allergy Clin Immunol 2011; 127(3): 757–764.
    • (2011) J Allergy Clin Immunol , vol.127 , Issue.3 , pp. 757-764
    • Saude, E.J.1    Skappak, C.D.2    Regush, S.3
  • 12
    • 84936817781 scopus 로고    scopus 로고
    • Metabolomic endotype of asthma
    • Comhair SA, McDunn J, Bennett C, et al. Metabolomic endotype of asthma. J Immunol 2015; 195: 643–650.
    • (2015) J Immunol , vol.195 , pp. 643-650
    • Comhair, S.A.1    McDunn, J.2    Bennett, C.3
  • 13
    • 84938513563 scopus 로고    scopus 로고
    • Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms
    • Hinks TS, Zhou X, Staples KJ, et al. Innate and adaptive T cells in asthmatic patients: relationship to severity and disease mechanisms. J Allergy Clin Immunol 2015; 136: 323–333.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 323-333
    • Hinks, T.S.1    Zhou, X.2    Staples, K.J.3
  • 14
    • 34047261246 scopus 로고    scopus 로고
    • Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease
    • Vijayanand P, Seumois G, Pickard C, et al. Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease. N Engl J Med 2007; 356: 1410–1422.
    • (2007) N Engl J Med , vol.356 , pp. 1410-1422
    • Vijayanand, P.1    Seumois, G.2    Pickard, C.3
  • 15
    • 79959913950 scopus 로고    scopus 로고
    • Human serum metabolome C. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
    • Dunn WB, Broadhurst D, Begley P, et al. Human serum metabolome C. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat Protoc 2011; 6: 1060–1083.
    • (2011) Nat Protoc , vol.6 , pp. 1060-1083
    • Dunn, W.B.1    Broadhurst, D.2    Begley, P.3
  • 16
    • 84878275118 scopus 로고    scopus 로고
    • Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow
    • Kirwan JA, Broadhurst DI, Davidson RL, et al. Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow. Anal Bioanal Chem 2013; 405: 5147–5157.
    • (2013) Anal Bioanal Chem , vol.405 , pp. 5147-5157
    • Kirwan, J.A.1    Broadhurst, D.I.2    Davidson, R.L.3
  • 18
    • 84951931682 scopus 로고    scopus 로고
    • Exploring the mode of action of dithranol therapy for psoriasis: A metabolomic analysis using HaCaT cells
    • Hollywood KA, Winder CL, Dunn WB, et al. Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells. Mol Biosyst 2015; 11: 2198–2209.
    • (2015) Mol Biosyst , vol.11 , pp. 2198-2209
    • Hollywood, K.A.1    Winder, C.L.2    Dunn, W.B.3
  • 20
    • 0034960264 scopus 로고    scopus 로고
    • Missing value estimation methods for DNA microarrays
    • Troyanskaya O, Cantor M, Sherlock G, et al. Missing value estimation methods for DNA microarrays. Bioinformatics 2001; 17: 520–525.
    • (2001) Bioinformatics , vol.17 , pp. 520-525
    • Troyanskaya, O.1    Cantor, M.2    Sherlock, G.3
  • 21
    • 0345016307 scopus 로고    scopus 로고
    • Giving meaningful interpretation to ordination axes: Assessing loading significance in principal component analysis
    • Peres-Neto PR, Jackson DA, Somers KM. Giving meaningful interpretation to ordination axes: assessing loading significance in principal component analysis. Ecology 2003; 84: 2347–2363.
    • (2003) Ecology , vol.84 , pp. 2347-2363
    • Peres-Neto, P.R.1    Jackson, D.A.2    Somers, K.M.3
  • 22
    • 84883427602 scopus 로고    scopus 로고
    • Sphingolipids and susceptibility to asthma
    • Levy BD. Sphingolipids and susceptibility to asthma. N Engl J Med 2013; 369: 976–978.
    • (2013) N Engl J Med , vol.369 , pp. 976-978
    • Levy, B.D.1
  • 23
    • 85011570000 scopus 로고    scopus 로고
    • The metabolomics of asthma control: A promising link between genetics and disease
    • McGeachie MJ, Dahlin A, Qiu W, et al. The metabolomics of asthma control: a promising link between genetics and disease. Immun Inflamm Dis 2015; 3: 224–238.
    • (2015) Immun Inflamm Dis , vol.3 , pp. 224-238
    • McGeachie, M.J.1    Dahlin, A.2    Qiu, W.3
  • 24
    • 0030060835 scopus 로고    scopus 로고
    • Nocturnal cortisol secretion in healthy adults before and after inhalation of budesonide
    • Nikolaizik WH, Marchant JL, Preece MA, et al. Nocturnal cortisol secretion in healthy adults before and after inhalation of budesonide. Am J Respir Crit Care Med 1996; 153: 97–101.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 97-101
    • Nikolaizik, W.H.1    Marchant, J.L.2    Preece, M.A.3
  • 25
    • 0030008193 scopus 로고    scopus 로고
    • Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients
    • Clark DJ, Grove A, Cargill RI, et al. Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients. Thorax 1996; 51: 262–266.
    • (1996) Thorax , vol.51 , pp. 262-266
    • Clark, D.J.1    Grove, A.2    Cargill, R.I.3
  • 26
    • 0036779687 scopus 로고    scopus 로고
    • Emerging roles of PPARs in inflammation and immunity
    • Daynes RA, Jones DC. Emerging roles of PPARs in inflammation and immunity. Nat Rev Immunol 2002; 2: 748–759.
    • (2002) Nat Rev Immunol , vol.2 , pp. 748-759
    • Daynes, R.A.1    Jones, D.C.2
  • 27
    • 0035120035 scopus 로고    scopus 로고
    • Cholesterol-lowering effect of garlic extracts and organosulfur compounds; human and animal studies
    • Yeh YY, Liu L. Cholesterol-lowering effect of garlic extracts and organosulfur compounds; human and animal studies. J Nutr 2001; 131: Suppl. 3, 989S–993S.
    • (2001) J Nutr , vol.131 , pp. 989S-993S
    • Yeh, Y.Y.1    Liu, L.2
  • 28
    • 84981625743 scopus 로고
    • Estimation of caffeine, theophylline, and theobromine in plant material
    • Jalal MAF, Collin HA. Estimation of caffeine, theophylline, and theobromine in plant material. New Phytol 1975; 76: 277–281.
    • (1975) New Phytol , vol.76 , pp. 277-281
    • Jalal, M.A.F.1    Collin, H.A.2
  • 29
    • 41149099000 scopus 로고    scopus 로고
    • Symbiotic gut microbes modulate human metabolic phenotypes
    • Li M, Wang B, Zhang M, et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci USA 2008; 105: 2117–2122.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2117-2122
    • Li, M.1    Wang, B.2    Zhang, M.3
  • 30
    • 12144259790 scopus 로고    scopus 로고
    • Dietary intake of fatty acids. Antioxidants and selected food groups and asthma in adults
    • Nagel G, Linseisen J. Dietary intake of fatty acids. antioxidants and selected food groups and asthma in adults. Eur J Clin Nutr 2005; 59: 8–15.
    • (2005) Eur J Clin Nutr , vol.59 , pp. 8-15
    • Nagel, G.1    Linseisen, J.2
  • 32
    • 33747419124 scopus 로고    scopus 로고
    • Pulmonary and vascular pharmacology of sphingosine 1-phosphate
    • Brinkmann V, Baumruker T. Pulmonary and vascular pharmacology of sphingosine 1-phosphate. Curr Opin Pharmacol 2006; 6: 244–250.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 244-250
    • Brinkmann, V.1    Baumruker, T.2
  • 33
    • 84905638795 scopus 로고    scopus 로고
    • Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways
    • Trankner D, Hahne N, Sugino K, et al. Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways. Proc Natl Acad Sci USA 2014; 111: 11515–11520.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 11515-11520
    • Trankner, D.1    Hahne, N.2    Sugino, K.3
  • 34
    • 17844392649 scopus 로고    scopus 로고
    • Oleoylethanolamide excites vagal sensory neurones. Induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1
    • Wang X, Miyares RL, Ahern GP. Oleoylethanolamide excites vagal sensory neurones. induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1. J Physiol 2005; 564(Pt 2): 541–547.
    • (2005) J Physiol , vol.564 , pp. 541-547
    • Wang, X.1    Miyares, R.L.2    Ahern, G.P.3
  • 35
    • 33746657575 scopus 로고    scopus 로고
    • A FAAH-regulated class of N-acyl taurines that activates TRP ion channels
    • Saghatelian A, McKinney MK, Bandell M, et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 2006; 45: 9007–9015.
    • (2006) Biochemistry , vol.45 , pp. 9007-9015
    • Saghatelian, A.1    McKinney, M.K.2    Bandell, M.3
  • 36
    • 65749107679 scopus 로고    scopus 로고
    • Role of TRPV1 in inflammation-induced airway hypersensitivity
    • Lee LY, Gu Q. Role of TRPV1 in inflammation-induced airway hypersensitivity. Curr Opin Pharmacol 2009; 9: 243–249.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 243-249
    • Lee, L.Y.1    Gu, Q.2
  • 37
    • 84896710602 scopus 로고    scopus 로고
    • Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma
    • McGarvey LP, Butler CA, Stokesberry S, et al. Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma. J Allergy Clin Immunol 2014; 133: 704–712 e704.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 704-712e704
    • McGarvey, L.P.1    Butler, C.A.2    Stokesberry, S.3
  • 38
    • 84907270790 scopus 로고    scopus 로고
    • The metabolite 5′-methylthioadenosine signals through the adenosine receptor A2B in melanoma
    • Limm K, Wallner S, Milenkovic VM, et al. The metabolite 5′-methylthioadenosine signals through the adenosine receptor A2B in melanoma. Eur J Cancer 2014; 50: 2714–2724.
    • (2014) Eur J Cancer , vol.50 , pp. 2714-2724
    • Limm, K.1    Wallner, S.2    Milenkovic, V.M.3
  • 39
    • 34248138496 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
    • Szallasi A, Cortright DN, Blum CA, et al. The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 2007; 6: 357–372.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 357-372
    • Szallasi, A.1    Cortright, D.N.2    Blum, C.A.3
  • 40
    • 80053231268 scopus 로고    scopus 로고
    • Adenosine triphosphate and adenosine receptors and pain
    • Beaulieu P, Lussier D, Porreca F, Dickenson A, eds. Seattle, IASP Press
    • Burnstock G, Sawynok J. Adenosine triphosphate and adenosine receptors and pain. In: Beaulieu P, Lussier D, Porreca F, Dickenson A, eds. Pharmacology of Pain. Seattle, IASP Press, 2010; pp. 303–326.
    • (2010) Pharmacology of Pain , pp. 303-326
    • Burnstock, G.1    Sawynok, J.2
  • 43
    • 2942707641 scopus 로고    scopus 로고
    • Serum dehydroepiandrosterone sulfate concentration as an indicator of adrenocortical suppression during inhaled steroid therapy in adult asthmatic patients
    • Kannisto S, Laatikainen A, Taivainen A, et al. Serum dehydroepiandrosterone sulfate concentration as an indicator of adrenocortical suppression during inhaled steroid therapy in adult asthmatic patients. Eur J Endocrinol 2004; 150: 687–690.
    • (2004) Eur J Endocrinol , vol.150 , pp. 687-690
    • Kannisto, S.1    Laatikainen, A.2    Taivainen, A.3
  • 44
    • 53849148238 scopus 로고    scopus 로고
    • Prolyl-hydroxyproline dipeptide in non-hydrolyzed morning urine and its value in postmenopausal osteoporosis
    • Husek P, Svagera Z, Vsiansky F, et al. Prolyl-hydroxyproline dipeptide in non-hydrolyzed morning urine and its value in postmenopausal osteoporosis. Clin Chem Lab Med 2008; 46: 1391–1397.
    • (2008) Clin Chem Lab Med , vol.46 , pp. 1391-1397
    • Husek, P.1    Svagera, Z.2    Vsiansky, F.3
  • 46
    • 0034701480 scopus 로고    scopus 로고
    • Inhaled corticosteroid use and bone-mineral density in patients with asthma
    • Wong CA, Walsh LJ, Smith CJ, et al. Inhaled corticosteroid use and bone-mineral density in patients with asthma. Lancet 2000; 355: 1399–1403.
    • (2000) Lancet , vol.355 , pp. 1399-1403
    • Wong, C.A.1    Walsh, L.J.2    Smith, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.