Nocturnal cortisol secretion in healthy adults before and after inhalation of budesonide

American Journal of Respiratory and Critical Care Medicine

Volumn 153, Issue 1, 1996, Pages 97-101

  Nikolaizik, W H ^b   Marchant, J L ^b   Preece, M A ^b   Warner, J O ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; HYDROCORTISONE;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DOSE RESPONSE; ENDOCRINE FUNCTION TEST; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE RELEASE; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SINGLE BLIND PROCEDURE;

EID: 0030060835     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.153.1.8542169     Document Type: Article

References (22)

1. Law, C. M., J. L. Marchant, J. W. Honour, M. A. Preece, and J. O. Warner. 1986. Nocturnal adrenal suppression in asthmatic children taking inhaled beclomethasone dipropionate. Lancet 1:942-944.
2. Law, C. M., M. A. Preece, and J. O. Warner. 1987. Nocturnal adrenal suppression in children inhaling beclomethasone dipropionate. Lancet 1:1321.
3. Priftis, K., A. D. Milner, E. Conway, and J. W. Honour. 1990. Adrenal function in asthma. Arch. Dis. Child. 65:838-840.
4. Nikolaizik, W. H., J. L. Marchant, M. A. Preece, and J. O. Warner. 1994. Endocrine and lung function in asthmatic children on inhaled corticosteroids. Am. J. Respir. Crit. Care Med. 150:624-628.
5. Dohlwitz, A., and A. Uppfeldt. 1985. Schmerzlinderung bei Venenpunktion. Anaesthesist 34:355-358.
6. Hallen, B., and A. Uppfeldt. 1982. Does lidocaine-prilicaine cream permit painfree insertion of IV catheters in children? Anesthesiology 57: 340-342.
7. Harris, D. M. 1975. Properties and therapeutic uses of some corticosteroids with enhanced topical potency. J. Steroid Biochem. 6: 711-716.
8. Löfdahl, C. G., T. Mellstrand, and N. Svedmyr. 1984. Glucocorticoids and asthma: studies of resistance and systemic effects of glucocorticoids. Eur. J. Respir. Dis. 65(Suppl. 136):69-79.
9. Vlasses, P. H., R. K. Ferguson, J. R. Koplin, R. A. Clementi, and P. J. Green. 1981. Adrenocortical function after chronic inhalation of fluocortinbutyl and beclomethasone dipropionate. Clin. Pharmcol. Ther. 29:643-649.
10. Mygind, N., and I. Hansen. 1973. Beclomethasone dipropionate aerosol effect on the adrenals in normal persons. Acta Allergol. 28:211-218.
11. Sherman, B., M. Weinberger, H. Chen-Walden, and H. Wendt. 1982. Further studies on the effects of inhaled glucocorticoids on pituitary-adrenal function in healthy adults. J. Allergy Clin. Immunol. 69: 208-212.
12. Crowley, S., P. C. Hindmarsh, W. J. Honour, and C. G. D. Brook. 1993. Reproducibility of the cortisol response to stimulation with a low dose of ACTH(1-24): the effect of basal cortisol levels and comparison of low-dose with high-dose secretory dynamics. J. Endocrinol. 136:167-172.
13. Wyatt, R., J. Waschek, M. Weinberger, and B. Sherman. 1978. Effects of inhaled beclomethasone dipropionate and alternate-day prednisone on pituitary-adrenal function in children with chronic asthma. N. Engl. J. Med. 299:1387-1392.
14. Nassif, E., M. Weinberger, B. Sherman, and K. Brown. 1987. Extrapulmonary effects of maintenance corticosteroid therapy with alternate-day prednisone and inhaled beclomethasone in children with chronic asthma. J. Allergy Clin. Immunol. 80:518-529.
15. Ryrfeldt, A., P. Andersson, S. Edsbäcker, M. Tönnesson, D. Davies, and R. Pauwels. 1982. Pharmacokinetics and metabolism of budesonide, a selective glucocorticoid. Eur. J. Respir. Dis. 63(Suppl. 122):86-95.
16. Pouw, E. M., M. F. Prummel, H. Oosting, C. M. Roos, and E. Endert. 1991. Beclomethasone inhalation decreases serum osteocalcin concentrations. B.M.J. 302:627-628.
17. Teelucksingh, S., P. L. Padfield, L. Tibi, K. J. Gough, and P. R. Holt. 1991. Inhaled corticosteroids, bone formation, and osteocalcin. Lancet 338:60-61.
18. Jennings, B. H., K. E. Andersson, and S. A. Johansson. 1991. Assessment of systemic effects of inhaled glucocorticoids: comparison of the effects of inhaled budesonide and oral prednisolone on adrenal function and markers of bone turnover. Eur. J. Clin. Pharmacol. 40:77-82.
19. Toogood, J. H., B. H. Jennings, A. B. Hodsman, J. Baskerville, and L. J. Fraher. 1991. Effects of dose and dosing schedule of inhaled budesonide on bone turnover. J. Allergy Clin. Immunol. 88:572-580.
20. Packe, G. E., J. G. Douglas, A. F. McDonald, S. P. Robins, and D. M. Reid. 1992. Bone density in asthmatic patients taking high dose inhaled beclomethasone dipropionate and intermittent systemic corticosteroids. Thorax 47:414-417.
21. Kruszynska, Y. T., M. Greenstone, P. D. Home, and N. J. Cooke. 1987. Effect of high dose inhaled beclomethasone dipropionate on carbohydrate and lipid metabolism in normal subjects. Thorax 42:881-884.
22. Ebden, P., P. McNally, A. Samanta, and G. J. Fancourt. 1989. The effects of high dose inhaled beclomethasone dipropionate on glucose and lipid profiles in normal and diet controlled diabetic subjects. Respir. Med. 83:289-291.