메뉴 건너뛰기




Volumn 127, Issue 3, 2011, Pages 757-764.e6

Metabolomic profiling of asthma: Diagnostic utility of urine nuclear magnetic resonance spectroscopy

Author keywords

Asthma; biomarkers; inflammation; metabolomics; NMR; urine

Indexed keywords

1 METHYLNICOTINAMIDE; 2 METHYLGLUTARIC ACID; 2 OXOGLUTARIC ACID; 3 HYDROXY 3 METHYLGLUTARIC ACID; 3 METHYLADIPATE; 4 AMINOHIPPURIC ACID; ACETONE; ACETYLCARNITINE; ACONITIC ACID; ADENINE; ADIPIC ACID; ALANINE; BIOLOGICAL MARKER; CREATINE; DIMETHYLAMINE; FORMIC ACID; FUMARIC ACID; GLUCOSE; GLYCOLIC ACID; IMIDAZOLE; INOSITOL; LACTIC ACID; OXALOACETIC ACID; PHENYLACETYLENE; PHENYLACETYLGLYCINE; PHENYLALANINE; TELE METHYLHISTAMINE; THREONINE; TRYPTOPHAN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 79952309777     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.12.1077     Document Type: Article
Times cited : (148)

References (53)
  • 1
    • 47949119866 scopus 로고    scopus 로고
    • Pathogenesis of asthma
    • S.T. Holgate Pathogenesis of asthma Clin Exp Allergy 38 2008 872 897
    • (2008) Clin Exp Allergy , vol.38 , pp. 872-897
    • Holgate, S.T.1
  • 2
    • 61849110311 scopus 로고    scopus 로고
    • Biomarkers in the assessment and management of airways diseases
    • D.R. Taylor, and I.D. Pavord Biomarkers in the assessment and management of airways diseases Postgrad Med J 84 2008 628 634 quiz 33
    • (2008) Postgrad Med J , vol.84 , pp. 628-634
    • Taylor, D.R.1    Pavord, I.D.2
  • 4
    • 33846937320 scopus 로고    scopus 로고
    • Basic mechanisms of development of airway structural changes in asthma
    • DOI 10.1183/09031936.00053506
    • E.D. Fixman, A. Stewart, and J.G. Martin Basic mechanisms of development of airway structural changes in asthma Eur Respir J 29 2007 379 389 (Pubitemid 46231919)
    • (2007) European Respiratory Journal , vol.29 , Issue.2 , pp. 379-389
    • Fixman, E.D.1    Stewart, A.2    Martin, J.G.3
  • 6
    • 31144451043 scopus 로고    scopus 로고
    • Biomarkers predicting response to corticosteroid therapy in asthma
    • DOI 10.2165/00151829-200504050-00002
    • C.E. Brightling, R.H. Green, and I.D. Pavord Biomarkers predicting response to corticosteroid therapy in asthma Treat Respir Med 4 2005 309 316 (Pubitemid 43127499)
    • (2005) Treatments in Respiratory Medicine , vol.4 , Issue.5 , pp. 309-316
    • Brightling, C.E.1    Green, R.H.2    Pavord, I.D.3
  • 8
    • 33846252642 scopus 로고    scopus 로고
    • Quantitative sputum cell counts as a marker of airway inflammation in clinical practice
    • DOI 10.1097/ACI.0b013e328013e3c2, PII 0013083220070200000018
    • F.E. Hargreave Quantitative sputum cell counts as a marker of airway inflammation in clinical practice Curr Opin Allergy Clin Immunol 7 2007 102 106 (Pubitemid 46095894)
    • (2007) Current Opinion in Allergy and Clinical Immunology , vol.7 , Issue.1 , pp. 102-106
    • Hargreave, F.E.1
  • 10
    • 52049108262 scopus 로고    scopus 로고
    • Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: A randomised controlled trial
    • S.J. Szefler, H. Mitchell, C.A. Sorkness, P.J. Gergen, G.T. O'Connor, and W.J. Morgan Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial Lancet 372 2008 1065 1072
    • (2008) Lancet , vol.372 , pp. 1065-1072
    • Szefler, S.J.1    Mitchell, H.2    Sorkness, C.A.3    Gergen, P.J.4    O'Connor, G.T.5    Morgan, W.J.6
  • 11
    • 58449117420 scopus 로고    scopus 로고
    • Metabolomics in pharmaceutical research and development: Metabolites, mechanisms and pathways
    • E.Y. Xu, W.H. Schaefer, and Q. Xu Metabolomics in pharmaceutical research and development: metabolites, mechanisms and pathways Curr Opin Drug Discov Devel 12 2009 40 52
    • (2009) Curr Opin Drug Discov Devel , vol.12 , pp. 40-52
    • Xu, E.Y.1    Schaefer, W.H.2    Xu, Q.3
  • 15
    • 63049090930 scopus 로고    scopus 로고
    • Exploring human metabolites using the human metabolome database
    • I.J. Forsythe, and D.S. Wishart Exploring human metabolites using the human metabolome database Curr Protoc Bioinformatics 2009 Chapter 14:Unit14 8
    • (2009) Curr Protoc Bioinformatics
    • Forsythe, I.J.1    Wishart, D.S.2
  • 16
    • 79952297863 scopus 로고    scopus 로고
    • The use of nuclear magnetic resonance analysis of urine in the diagnosis of asthma
    • C. Skappak Ejs, K. Cook, B. Rowe, and D.J. Adamko The use of nuclear magnetic resonance analysis of urine in the diagnosis of asthma Am J Respir Crit Care Med 179 2009 A2531
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 2531
    • Skappak Ejs, C.1    Cook, K.2    Rowe, B.3    Adamko, D.J.4
  • 18
    • 67650296388 scopus 로고    scopus 로고
    • A novel study design to investigate the early-life origins of asthma in children (SAGE study)
    • A.L. Kozyrskyj, K.T. HayGlass, A.J. Sandford, P.D. Pare, M. Chan-Yeung, and A.B. Becker A novel study design to investigate the early-life origins of asthma in children (SAGE study) Allergy 64 2009 1185 1193
    • (2009) Allergy , vol.64 , pp. 1185-1193
    • Kozyrskyj, A.L.1    Hayglass, K.T.2    Sandford, A.J.3    Pare, P.D.4    Chan-Yeung, M.5    Becker, A.B.6
  • 19
    • 33749179972 scopus 로고    scopus 로고
    • Optimization of NMR analysis of biological fluids for quantitative accuracy
    • DOI 10.1007/s11306-006-0023-5
    • E.J. Saude, C.M. Slupsky, and B.D. Sykes Optimization of NMR analysis of biological fluids for quantitative accuracy Metabolomics 2 2006 113 123 (Pubitemid 44473570)
    • (2006) Metabolomics , vol.2 , Issue.3 , pp. 113-123
    • Saude, E.J.1    Slupsky, C.M.2    Sykes, B.D.3
  • 20
    • 33947392610 scopus 로고    scopus 로고
    • Urine stability for metabolomic studies: Effects of preparation and storage
    • DOI 10.1007/s11306-006-0042-2
    • E.J. Saude, and B.D. Sykes Urine stability for metabolomic studies: effects of preparation and storage Metabolomics 3 2007 19 27 (Pubitemid 46453528)
    • (2007) Metabolomics , vol.3 , Issue.1 , pp. 19-27
    • Saude, E.J.1    Sykes, B.D.2
  • 21
    • 36049042571 scopus 로고    scopus 로고
    • Variation of metabolites in normal human urine
    • DOI 10.1007/s11306-007-0091-1
    • E.J. Saude, D. Adamko, B.H. Rowe, T. Marrie, and B.D. Sykes Variation of metabolites in normal human urine Metabolomics 3 2007 439 451 (Pubitemid 350090674)
    • (2007) Metabolomics , vol.3 , Issue.4 , pp. 439-451
    • Saude, E.J.1    Adamko, D.2    Rowe, B.H.3    Marrie, T.4    Sykes, B.D.5
  • 24
    • 0033019597 scopus 로고    scopus 로고
    • Lack of relationship between eosinophil cationic protein and eosinophil protein X in nasal lavage and urine and the severity of childhood asthma in a 6-month follow-up study
    • DOI 10.1046/j.1365-2222.1999.00586.x
    • C. Wojnarowski, B. Roithner, D.Y. Koller, G. Halmerbauer, C. Gartner, and E. Tauber Lack of relationship between eosinophil cationic protein and eosinophil protein X in nasal lavage and urine and the severity of childhood asthma in a 6-month follow-up study Clin Exp Allergy 29 1999 926 932 (Pubitemid 29317803)
    • (1999) Clinical and Experimental Allergy , vol.29 , Issue.7 , pp. 926-932
    • Wojnarowski, C.1    Roithner, B.2    Koller, D.Y.3    Halmerbauer, G.4    Gartner, C.5    Tauber, E.6    Frischer, T.7
  • 25
    • 0033772785 scopus 로고    scopus 로고
    • Urinary excretion of leukotriene E4 and eosinophil protein X in children with atopic asthma
    • C. Severien, A. Artlich, S. Jonas, and G. Becher Urinary excretion of leukotriene E4 and eosinophil protein X in children with atopic asthma Eur Respir J 16 2000 588 592
    • (2000) Eur Respir J , vol.16 , pp. 588-592
    • Severien, C.1    Artlich, A.2    Jonas, S.3    Becher, G.4
  • 26
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • G.L. Semenza Targeting HIF-1 for cancer therapy Nat Rev Cancer 3 2003 721 732 (Pubitemid 37328811)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 28
    • 0002301232 scopus 로고    scopus 로고
    • Metabonomic applications in toxicity screening and disease diagnosis
    • J.P. Shockcor, and E. Holmes Metabonomic applications in toxicity screening and disease diagnosis Curr Top Med Chem 2 2002 35 51
    • (2002) Curr Top Med Chem , vol.2 , pp. 35-51
    • Shockcor, J.P.1    Holmes, E.2
  • 29
    • 30844471152 scopus 로고    scopus 로고
    • Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition
    • J. Azmi, J. Connelly, E. Holmes, J.K. Nicholson, R.F. Shore, and J.L. Griffin Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition Biomarkers 10 2005 401 416
    • (2005) Biomarkers , vol.10 , pp. 401-416
    • Azmi, J.1    Connelly, J.2    Holmes, E.3    Nicholson, J.K.4    Shore, R.F.5    Griffin, J.L.6
  • 32
    • 0036229938 scopus 로고    scopus 로고
    • Metabolic, nutritional, iatrogenic, and artifactual sources of urinary organic acids: A comprehensive table
    • A. Kumps, P. Duez, and Y. Mardens Metabolic, nutritional, iatrogenic, and artifactual sources of urinary organic acids: a comprehensive table Clin Chem 48 2002 708 717 (Pubitemid 34439102)
    • (2002) Clinical Chemistry , vol.48 , Issue.5 , pp. 708-717
    • Kumps, A.1    Duez, P.2    Mardens, Y.3
  • 33
    • 0037385013 scopus 로고    scopus 로고
    • The role of carnitine in myocardial dysfunction
    • D.F. Pauly, and C.J. Pepine The role of carnitine in myocardial dysfunction Am J Kidney Dis 41 2003 S35 S43
    • (2003) Am J Kidney Dis , vol.41
    • Pauly, D.F.1    Pepine, C.J.2
  • 34
    • 48749091722 scopus 로고    scopus 로고
    • Change in the membranous lipid composition accelerates lipid peroxidation in young rat hearts subjected to 2 weeks of hypoxia followed by hyperoxia
    • T. Oka, T. Itoi, N. Terada, H. Nakanishi, R. Taguchi, and K. Hamaoka Change in the membranous lipid composition accelerates lipid peroxidation in young rat hearts subjected to 2 weeks of hypoxia followed by hyperoxia Circ J 72 2008 1359 1366
    • (2008) Circ J , vol.72 , pp. 1359-1366
    • Oka, T.1    Itoi, T.2    Terada, N.3    Nakanishi, H.4    Taguchi, R.5    Hamaoka, K.6
  • 37
    • 0000944474 scopus 로고
    • A study of creatine metabolism in diseases causing muscle wasting
    • C. Fitch, and D. Sinton A study of creatine metabolism in diseases causing muscle wasting J Clin Invest 43 1964 444 452
    • (1964) J Clin Invest , vol.43 , pp. 444-452
    • Fitch, C.1    Sinton, D.2
  • 39
    • 0016173316 scopus 로고
    • The inhibitory effect of nicotinamide on asthma-like symptoms and eosinophilia in guinea pigs, anaphylactic mast cell degranulation in mice, and histamine release from rat isolated peritoneal mast cells by compound 48-80
    • E. Bekier, J. Wyczolkowska, H. Szyc, and C. Maslinski The inhibitory effect of nicotinamide on asthma-like symptoms and eosinophilia in guinea pigs, anaphylactic mast cell degranulation in mice, and histamine release from rat isolated peritoneal mast cells by compound 48-80 Int Arch Allergy Appl Immunol 47 1974 737 748
    • (1974) Int Arch Allergy Appl Immunol , vol.47 , pp. 737-748
    • Bekier, E.1    Wyczolkowska, J.2    Szyc, H.3    Maslinski, C.4
  • 42
    • 0034114734 scopus 로고    scopus 로고
    • Determination of histamine, 1-methylhistasnine and N-methylhistamine by capillary electrophoresis with micelles
    • DOI 10.1002/1099-0801(200005)14:3<184::AID-BMC970>3.0.CO;2-2
    • F. Nishiwaki, K. Kuroda, Y. Inoue, and G. Endo Determination of histamine, 1-methylhistamine and N-methylhistamine by capillary electrophoresis with micelles Biomed Chromatogr 14 2000 184 187 (Pubitemid 30255905)
    • (2000) Biomedical Chromatography , vol.14 , Issue.3 , pp. 184-187
    • Nishiwaki, F.1    Kuroda, K.2    Inoue, Y.3    Endo, G.4
  • 44
    • 0025635910 scopus 로고
    • Determination of N-methylhistamine in urine as an indicator of histamine release in immediate allergic reactions
    • V. Stephan, A. Zimmermann, J. Kuhr, and R. Urbanek Determination of N-methylhistamine in urine as an indicator of histamine release in immediate allergic reactions J Allergy Clin Immunol 86 1990 862 868
    • (1990) J Allergy Clin Immunol , vol.86 , pp. 862-868
    • Stephan, V.1    Zimmermann, A.2    Kuhr, J.3    Urbanek, R.4
  • 45
    • 69149084827 scopus 로고    scopus 로고
    • Manipulation of indoleamine 2,3 dioxygenase; A novel therapeutic target for treatment of diseases
    • P. Tan, and A. Bharath Manipulation of indoleamine 2,3 dioxygenase; a novel therapeutic target for treatment of diseases Expert Opin Ther Targets 2009
    • (2009) Expert Opin Ther Targets
    • Tan, P.1    Bharath, A.2
  • 48
    • 33749179972 scopus 로고    scopus 로고
    • Optimization of NMR analysis of biological fluids for quantitative accuracy
    • DOI 10.1007/s11306-006-0023-5
    • E.J. Saude, C.M. Slupsky, and B.D. Sykes Optimization of NMR analysis of biological fluids for quantitative accuracy Metabolomics 2 2006 113 123 (Pubitemid 44473570)
    • (2006) Metabolomics , vol.2 , Issue.3 , pp. 113-123
    • Saude, E.J.1    Slupsky, C.M.2    Sykes, B.D.3
  • 49
    • 33947392610 scopus 로고    scopus 로고
    • Urine stability for metabolomic studies: Effects of preparation and storage
    • DOI 10.1007/s11306-006-0042-2
    • E.J. Saude, and B.D. Sykes Urine stability for metabolomic studies: effects of preparation and storage Metabolomics 3 2007 19 27 (Pubitemid 46453528)
    • (2007) Metabolomics , vol.3 , Issue.1 , pp. 19-27
    • Saude, E.J.1    Sykes, B.D.2
  • 50
    • 36049042571 scopus 로고    scopus 로고
    • Variation of metabolites in normal human urine
    • DOI 10.1007/s11306-007-0091-1
    • E.J. Saude, D. Adamko, B.H. Rowe, T. Marrie, and B.D. Sykes Variation of metabolites in normal human urine Metabolomics 3 2007 439 451 (Pubitemid 350090674)
    • (2007) Metabolomics , vol.3 , Issue.4 , pp. 439-451
    • Saude, E.J.1    Adamko, D.2    Rowe, B.H.3    Marrie, T.4    Sykes, B.D.5
  • 52
    • 0019327003 scopus 로고
    • A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules
    • A. Kumar, R.R. Ernst, and K. Wuthrich A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules Biochem Biophys Res Commun 95 1980 1 6
    • (1980) Biochem Biophys Res Commun , vol.95 , pp. 1-6
    • Kumar, A.1    Ernst, R.R.2    Wuthrich, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.