Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

Immunity

Volumn 47, Issue 5, 2017, Pages 928-942.e7

  Dalmas, Elise ^a,b   Lehmann, Frank M ^b   Dror, Erez ^a,b   Wueest, Stephan ^c   Thienel, Constanze ^a,b   Borsigova, Marcela ^a,b   Stawiski, Marc ^a,b   Traunecker, Emmanuel ^b   Lucchini, Fabrizio C ^c   Dapito, Dianne H ^d   Kallert, Sandra M ^b   Guigas, Bruno ^e   Pattou, Francois ^f   Kerr Conte, Julie ^f   Maechler, Pierre ^g   Girard, Jean Philippe ^h   Konrad, Daniel ^c   Wolfrum, Christian ^d   Böni Schnetzler, Marianne ^a,b   Finke, Daniela ^b   Donath, Marc Y ^a,b   more..

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^d ETH ZURICH   (Switzerland)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^f UNIV LILLE   (France)

^g UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^h UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

Aldh1a2; beta cells; ILC2; innate lymphoid cells; insulin; interleukin 33; islet

Indexed keywords

ALDH1A2 PROTEIN; ALPHA SMOOTH MUSCLE ACTIN; CD45 ANTIGEN; EPITHELIAL CELL ADHESION MOLECULE; GALACTOSIDASE; GLUCOSE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN G; INSULIN; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 5; KLRG1 PROTEIN; PALMITIC ACID; PROTEIN; RETINOIC ACID; RETINOL; STEM CELL ANTIGEN 1; THY 1 ANTIGEN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; BONE MARROW DERIVED DENDRITIC CELL; BROWN ADIPOSE TISSUE; CELL STRESS; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DIABETES MELLITUS; DIET INDUCED OBESITY; DOWN REGULATION; EOSINOPHIL; EPIDIDYMIS FAT; EX VIVO STUDY; EXOCRINE PANCREAS; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE TEST; INSULIN RELEASE; INSULIN RESPONSE; INSULIN SENSITIVITY; LYMPHOID CELL; MACROPHAGE; MALE; MESENCHYME CELL; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY T LYMPHOCYTE; RETINOL DEFICIENCY; UPREGULATION; WHITE ADIPOSE TISSUE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECTS; IMMUNOLOGY; INFLAMMATION; LYMPHOCYTE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; HUMANS; INFLAMMATION; INSULIN; INTERLEUKIN-33; ISLETS OF LANGERHANS; LYMPHOCYTES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELOID CELLS; TRETINOIN; VITAMIN A;

EID: 85034272882     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.10.015     Document Type: Article

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