Octenylsuccinate hydroxypropyl phytoglycogen enhances the solubility and in-vitro antitumor efficacy of niclosamide

International Journal of Pharmaceutics

Volumn 535, Issue 1-2, 2018, Pages 157-163

  Xie, Ying ^a   Yao, Yuan ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Cancer cell inhibition; Niclosamide; Octenylsuccinate hydroxypropyl phytoglycogen; Solubility; Transdermal

Indexed keywords

ANTINEOPLASTIC AGENT; BIOPOLYMER; DENDRIMER; GLYCOGEN; HYDROXYL GROUP; NICLOSAMIDE; OCTENYLSUCCINATE HYDROXYPROPYL PHYTOGLYCOGEN; PROPANE; SUCCINIC ACID; UNCLASSIFIED DRUG; DRUG CARRIER; SUCCINIC ACID DERIVATIVE;

A-549 CELL LINE; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTALLIZATION; CYTOTOXICITY ASSAY; DISPERSION; DRUG EFFICACY; DRUG INHIBITION; DRUG SOLUBILITY; FEMALE; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY; MALE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; SOLID; X RAY POWDER DIFFRACTION; BIOLOGICAL MODEL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; DRUG FORMULATION; METABOLISM; SKIN; SKIN ABSORPTION; SOLUBILITY; SOLUTION AND SOLUBILITY;

A549 CELLS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; DRUG CARRIERS; DRUG COMPOUNDING; GLYCOGEN; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; NICLOSAMIDE; SKIN; SKIN ABSORPTION; SOLUBILITY; SOLUTIONS; SUCCINATES;

EID: 85033483663     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2017.11.004     Document Type: Article

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