Dendrimer-like alpha-d-glucan nanoparticles activate dendritic cells and are effective vaccine adjuvants

Journal of Controlled Release

Volumn 204, Issue , 2015, Pages 51-59

  Lu, Fangjia ^a   Mencia, Alejandra ^b   Bi, Lin ^b   Taylor, Aaron ^c   Yao, Yuan ^b   HogenEsch, Harm ^a  

^a PURDUE UNIVERSITY   (United States)

^b Department of Food Science ^*  (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Adjuvants; Dendritic cells; IL 1 ; Inflammation; Nanoparticles; Vaccines

Indexed keywords

ANTIGENS; COST EFFECTIVENESS; CYTOLOGY; DENDRIMERS; IMMUNE SYSTEM; NANOPARTICLES; PATHOLOGY; PROTEINS; VACCINES;

ADJUVANTS; COSTIMULATORY MOLECULES; DENDRITIC CELLS; ELECTROSTATIC ADSORPTION; INFLAMMATION; INTRAMUSCULAR INJECTIONS; POSITIVE SURFACE CHARGE; SYNTHETIC NANOPARTICLES;

CELLS;

ANTIGEN; DENDRIMER; GLUCAN; NANO 11 ANTIGEN; NANOPARTICLE; UNCLASSIFIED DRUG; VACCINE; (3-CHLORO-2-HYDROXYPROPYL)TRIMETHYLAMMONIUM CHLORIDE; CYTOKINE; IMMUNOLOGICAL ADJUVANT; OCTENYL SUCCINATE; OVALBUMIN; PROPANOL; QUATERNARY AMMONIUM DERIVATIVE; SUCCINIC ACID DERIVATIVE;

ADJUVANT THERAPY; ADSORPTION KINETICS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DENDRITIC CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATIC ELECTRICITY; SURFACE CHARGE; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; FEMALE; FLOW CYTOMETRY; IMMUNOLOGY; PARTICLE SIZE; SECRETION (PROCESS); SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DENDRIMERS; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; GLUCANS; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OVALBUMIN; PARTICLE SIZE; PROPANOLS; QUATERNARY AMMONIUM COMPOUNDS; SUCCINATES; SURFACE PROPERTIES;

EID: 84924426166     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.03.002     Document Type: Article

References (33)

1. G. Leroux-Roels Unmet needs in modern vaccinology: adjuvants to improve the immune response Vaccine 28 Suppl. 3 2010 C25 C36
2. L.A. Brito, and D.T. O'Hagan Designing and building the next generation of improved vaccine adjuvants J. Control. Release 190 2014 563 579
3. E.B. Lindblad Aluminium compounds for use in vaccines Immunol. Cell Biol. 82 2004 497 505
4. H. HogenEsch Mechanism of immunopotentiation and safety of aluminum adjuvants Front. Immunol. 4 2013 406
5. R.J. Talbot, D. Newton, N.D. Priest, J.G. Austin, and J.P. Day Inter-subject variability in the metabolism of aluminium following intravenous injection as citrate Hum. Exp. Toxicol. 14 1995 595 599
6. C. Minshall, J. Nadal, and C. Exley Aluminium in human sweat J. Trace Elem. Med. Biol. 28 2014 87 88
7. R. Rappuoli, C.W. Mandl, S. Black, and E. De Gregorio Vaccines for the twenty-first century society Nat. Rev. Immunol. 11 2011 865 872
8. D.T. O'Hagan, and E. De Gregorio The path to a successful vaccine adjuvant - 'the long and winding road' Drug Discov. Today 14 2009 541 551
9. A.E. Gregory, R. Titball, and D. Williamson Vaccine delivery using nanoparticles Frontiers Cell. Infect. Microbiol. 3 2013 13
10. L. Zhao, A. Seth, N. Wibowo, C.X. Zhao, N. Mitter, C. Yu, and A.P. Middelberg Nanoparticle vaccines Vaccine 32 2014 327 337
11. E. van Riet, A. Ainai, T. Suzuki, G. Kersten, and H. Hasegawa Combatting infectious diseases; nanotechnology as a platform for rational vaccine design Adv. Drug Deliv. Rev. 74C 2014 28 34
12. S.L. Scheffler, L. Huang, L. Bi, and Y. Yao In vitro digestibility and emulsification properties of phytoglycogen octenyl succinate J. Agric. Food Chem. 58 2010 5140 5146
13. L. Huang, and Y. Yao Particulate structure of phytoglycogen nanoparticles probed using amyloglucosidase Carbohydr. Polym. 83 2011 1665 1671
14. S.L. Scheffler, X. Wang, L. Huang, F. San-Martin Gonzalez, and Y. Yao Phytoglycogen octenyl succinate, an amphiphilic carbohydrate nanoparticle, and epsilon-polylysine to improve lipid oxidative stability of emulsions J. Agric. Food Chem. 58 2010 660 667
15. A. Sokolovska, S.L. Hem, and H. HogenEsch Activation of dendritic cells and induction of CD4(+) T cell differentiation by aluminum-containing adjuvants Vaccine 25 2007 4575 4585
16. G.T. Hermanson Bioconjugate Techniques 3rd ed. 2013 Academic Press, Inc. San Diego
17. F. Lu, and H. HogenEsch Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant Vaccine 31 2013 3979 3986
18. J.L. Putaux, A. Buleon, R. Borsali, and H. Chanzy Ultrastructural aspects of phytoglycogen from cryo-transmission electron microscopy and quasi-elastic light scattering data Int. J. Biol. Macromol. 26 1999 145 150
19. S.D. Xiang, A. Scholzen, G. Minigo, C. David, V. Apostolopoulos, P.L. Mottram, and M. Plebanski Pathogen recognition and development of particulate vaccines: does size matter? Methods 40 2006 1 9
20. X. Li, B.R. Sloat, N. Yanasarn, and Z. Cui Relationship between the size of nanoparticles and their adjuvant activity: data from a study with an improved experimental design Eur. J. Pharm. Biopharm. 78 2011 107 116
21. T. Fifis, A. Gamvrellis, B. Crimeen-Irwin, G.A. Pietersz, J. Li, P.L. Mottram, I.F. McKenzie, and M. Plebanski Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors J. Immunol. 173 2004 3148 3154
22. J.W. Mannhalter, H.O. Neychev, G.J. Zlabinger, R. Ahmad, and M.M. Eibl Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation Clin. Exp. Immunol. 61 1985 143 151
23. G.L. Morefield, A. Sokolovska, D. Jiang, H. HogenEsch, J.P. Robinson, and S.L. Hem Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro Vaccine 23 2005 1588 1595
24. S. Burgdorf, V. Lukacs-Kornek, and C. Kurts The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation J. Immunol. 176 2006 6770 6776
25. P. Kalinski, C.M. Hilkens, E.A. Wierenga, and M.L. Kapsenberg T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal Immunol. Today 20 1999 561 567
26. G. Lopez-Castejon, and D. Brough Understanding the mechanism of IL-1beta secretion Cytokine Growth Factor Rev. 22 2011 189 195
27. H. Li, S. Nookala, and F. Re Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release J. Immunol. 178 2007 5271 5276
28. P. Marrack, A.S. McKee, and M.W. Munks Towards an understanding of the adjuvant action of aluminium Nat. Rev. Immunol. 9 2009 287 293
29. F.A. Sharp, D. Ruane, B. Claass, E. Creagh, J. Harris, P. Malyala, M. Singh, D.T. O'Hagan, V. Petrilli, J. Tschopp, L.A. O'Neill, and E.C. Lavelle Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome Proc. Natl. Acad. Sci. U. S. A. 106 2009 870 875
30. M. Yang, K. Flavin, I. Kopf, G. Radics, C.H. Hearnden, G.J. McManus, B. Moran, A. Villalta-Cerdas, L.A. Echegoyen, S. Giordani, and E.C. Lavelle Functionalization of carbon nanoparticles modulates inflammatory cell recruitment and NLRP3 inflammasome activation Small 9 2013 4194 4206
31. S. Neumann, K. Burkert, R. Kemp, T. Rades, P. Rod Dunbar, and S. Hook Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants Immunol. Cell Biol. 92 2014 535 542
32. R. Li, X. Wang, Z. Ji, B. Sun, H. Zhang, C.H. Chang, S. Lin, H. Meng, Y.P. Liao, M. Wang, Z. Li, A.A. Hwang, T.B. Song, R. Xu, Y. Yang, J.I. Zink, A.E. Nel, and T. Xia Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity ACS Nano 7 2013 2352 2368
33. K. Niikura, T. Matsunaga, T. Suzuki, S. Kobayashi, H. Yamaguchi, Y. Orba, A. Kawaguchi, H. Hasegawa, K. Kajino, T. Ninomiya, K. Ijiro, and H. Sawa Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo ACS Nano 7 2013 3926 3938