Targeting glioma stem cells through combined BMI1 and EZH2 inhibition

Nature Medicine

Volumn 23, Issue 11, 2017, Pages 1352-1361

  Jin, Xun ^a,b,c   Kim, Leo J Y ^a,d,e   Wu, Qiulian ^a,e   Wallace, Lisa C ^a   Prager, Briana C ^a,d,e,f   Sanvoranart, Tanwarat ^a   Gimple, Ryan C ^a,d,e   Wang, Xiuxing ^a,e   Mack, Stephen C ^a,g   Miller, Tyler E ^a,d   Huang, Ping ^a   Valentim, Claudia L ^a   Zhou, Qi Gang ^a   Barnholtz Sloan, Jill S ^d   Bao, Shideng ^a,d,f   Sloan, Andrew E ^d,h   Rich, Jeremy N ^a,d,e,f  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c WENZHOU MEDICAL UNIVERSITY   (China)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF SAN DIEGO   (United States)

^f CASE WESTERN RESERVE UNIVERSITY   (United States)

^g BAYLOR COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; TRANSCRIPTION FACTOR EZH2; UBIQUITIN PROTEIN LIGASE E3; BMI1 PROTEIN, HUMAN; EZH2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; FEMALE; GENE ACTIVATION; GENE DISRUPTION; GERMLINE STEM CELL; GLIOBLASTOMA; GLIOMA STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL NICHE; TARGET CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CANCER STEM CELL; DRUG EFFECTS; GENETIC EPIGENESIS; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BRAIN NEOPLASMS; ENHANCER OF ZESTE HOMOLOG 2 PROTEIN; EPIGENESIS, GENETIC; GLIOBLASTOMA; HUMANS; MICE; NEOPLASTIC STEM CELLS; POLYCOMB REPRESSIVE COMPLEX 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 85033237290     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4415     Document Type: Article

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