Glucose feeds the TCA cycle via circulating lactate

Nature

Volumn 551, Issue 7678, 2017, Pages 115-118

  Hui, Sheng ^a   Ghergurovich, Jonathan M ^a   Morscher, Raphael J ^a   Jang, Cholsoon ^a   Teng, Xin ^a   Lu, Wenyun ^a   Esparza, Lourdes A ^b   Reya, Tannishtha ^b   Zhan, Le ^c,d   Yanxiang Guo, Jessie ^c,e,f   White, Eileen ^c,d   Rabinowitz, Joshua D ^a,c  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^d RUTGERS UNIVERSITY   (United States)

^e ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^f RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; GLUCOSE; LACTIC ACID; CARBON; GLUTAMINE;

CANCER; CARBON DIOXIDE; CELLS AND CELL COMPONENTS; GLUCOSE; MAMMAL; METABOLISM; NUTRIENT; OXIC CONDITIONS; QUANTITATIVE ANALYSIS; RODENT; SECONDARY METABOLITE; TUMOR;

ARTERIAL CIRCULATION; ARTICLE; CARBON SOURCE; CITRIC ACID CYCLE; DIET RESTRICTION; GENETIC MANIPULATION; GLUCONEOGENESIS; GLUCOSE INFUSION; GLYCOLYSIS; ISOTOPE TRACING; JUGULAR VEIN; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEADY STATE; THERMODYNAMICS; ANIMAL; BLOOD; BRAIN; GLUCOSE BLOOD LEVEL; METABOLISM; MOUSE; MUSCLE; PANCREAS TUMOR;

MAMMALIA; MUS;

ANIMALS; BLOOD GLUCOSE; BRAIN; CARBON; CITRIC ACID CYCLE; FASTING; GLUCOSE; GLUTAMINE; GLYCOLYSIS; LACTIC ACID; MICE; MUSCLES; PANCREATIC NEOPLASMS;

EID: 85032944832     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature24057     Document Type: Article

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