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Volumn 78, Issue , 2018, Pages 128-140

Energy-matched moderate and high intensity exercise training improves nonalcoholic fatty liver disease risk independent of changes in body mass or abdominal adiposity — A randomized trial

Author keywords

Hepatic steatosis; High intensity interval training; Moderate intensity continuous training; Nonalcoholic fatty liver disease

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C PEPTIDE; CYTOKERATIN 18; FATTY ACID; FETUIN A; GLUCOSE; INSULIN;

EID: 85032881057     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2017.08.012     Document Type: Article
Times cited : (96)

References (57)
  • 1
    • 57349116780 scopus 로고    scopus 로고
    • Causes and metabolic consequences of fatty liver
    • Stefan, N., Kantartzis, K., Haring, H.U., Causes and metabolic consequences of fatty liver. Endocr Rev 29 (2008), 939–960.
    • (2008) Endocr Rev , vol.29 , pp. 939-960
    • Stefan, N.1    Kantartzis, K.2    Haring, H.U.3
  • 2
    • 80555136061 scopus 로고    scopus 로고
    • Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • Musso, G., Gambino, R., Cassader, M., Pagano, G., Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity. Ann Med 43 (2011), 617–649.
    • (2011) Ann Med , vol.43 , pp. 617-649
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 3
    • 42949178538 scopus 로고    scopus 로고
    • Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
    • Korenblat, K.M., Fabbrini, E., Mohammed, B.S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 134 (2008), 1369–1375.
    • (2008) Gastroenterology , vol.134 , pp. 1369-1375
    • Korenblat, K.M.1    Fabbrini, E.2    Mohammed, B.S.3    Klein, S.4
  • 4
    • 38649111018 scopus 로고    scopus 로고
    • Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease
    • Fabbrini, E., Mohammed, B.S., Magkos, F., Korenblat, K.M., Patterson, B.W., Klein, S., Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology 134 (2008), 424–431.
    • (2008) Gastroenterology , vol.134 , pp. 424-431
    • Fabbrini, E.1    Mohammed, B.S.2    Magkos, F.3    Korenblat, K.M.4    Patterson, B.W.5    Klein, S.6
  • 5
    • 84955487817 scopus 로고    scopus 로고
    • Progression of carotid vascular damage and cardiovascular events in non-alcoholic fatty liver disease patients compared to the general population during 10 years of follow-up
    • Fracanzani, A.L., Tiraboschi, S., Pisano, G., Consonni, D., Baragetti, A., Bertelli, C., et al. Progression of carotid vascular damage and cardiovascular events in non-alcoholic fatty liver disease patients compared to the general population during 10 years of follow-up. Atherosclerosis 246 (2016), 208–213.
    • (2016) Atherosclerosis , vol.246 , pp. 208-213
    • Fracanzani, A.L.1    Tiraboschi, S.2    Pisano, G.3    Consonni, D.4    Baragetti, A.5    Bertelli, C.6
  • 6
    • 84909997067 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and vascular disease: state-of-the-art
    • Fargion, S., Porzio, M., Fracanzani, A.L., Nonalcoholic fatty liver disease and vascular disease: state-of-the-art. World J Gastroenterol 20 (2014), 13306–13324.
    • (2014) World J Gastroenterol , vol.20 , pp. 13306-13324
    • Fargion, S.1    Porzio, M.2    Fracanzani, A.L.3
  • 7
    • 84876130551 scopus 로고    scopus 로고
    • Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States
    • Kim, D., Kim, W.R., Kim, H.J., Therneau, T.M., Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States. Hepatology 57 (2013), 1357–1365.
    • (2013) Hepatology , vol.57 , pp. 1357-1365
    • Kim, D.1    Kim, W.R.2    Kim, H.J.3    Therneau, T.M.4
  • 10
    • 84893388150 scopus 로고    scopus 로고
    • Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats
    • Linden, M.A., Fletcher, J.A., Morris, E.M., Meers, G.M., Kearney, M.L., Crissey, J.M., et al. Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats. Am J Physiol Endocrinol Metab 306 (2014), E300–10.
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , pp. E300-10
    • Linden, M.A.1    Fletcher, J.A.2    Morris, E.M.3    Meers, G.M.4    Kearney, M.L.5    Crissey, J.M.6
  • 11
    • 84971455408 scopus 로고    scopus 로고
    • Aerobic exercise training in the treatment of non-alcoholic fatty liver disease related fibrosis
    • Linden, M.A., Sheldon, R.D., Meers, G.M., Ortinau, L.C., Morris, E.M., Booth, F.W., et al. Aerobic exercise training in the treatment of non-alcoholic fatty liver disease related fibrosis. J Physiol 594 (2016), 5271–5284.
    • (2016) J Physiol , vol.594 , pp. 5271-5284
    • Linden, M.A.1    Sheldon, R.D.2    Meers, G.M.3    Ortinau, L.C.4    Morris, E.M.5    Booth, F.W.6
  • 14
    • 84859431733 scopus 로고    scopus 로고
    • Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease
    • Schultz, A., Mendonca, L.S., Aguila, M.B., Mandarim-de-Lacerda, C.A., Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease. Exp Toxicol Pathol 64 (2012), 273–282.
    • (2012) Exp Toxicol Pathol , vol.64 , pp. 273-282
    • Schultz, A.1    Mendonca, L.S.2    Aguila, M.B.3    Mandarim-de-Lacerda, C.A.4
  • 15
    • 77952947523 scopus 로고    scopus 로고
    • Beneficial effects of exercise training (treadmill) on insulin resistance and nonalcoholic fatty liver disease in high-fat fed C57BL/6 mice
    • Marques, C.M., Motta, V.F., Torres, T.S., Aguila, M.B., Mandarim-de-Lacerda, C.A., Beneficial effects of exercise training (treadmill) on insulin resistance and nonalcoholic fatty liver disease in high-fat fed C57BL/6 mice. Braz J Med Biol Res 43 (2010), 467–475.
    • (2010) Braz J Med Biol Res , vol.43 , pp. 467-475
    • Marques, C.M.1    Motta, V.F.2    Torres, T.S.3    Aguila, M.B.4    Mandarim-de-Lacerda, C.A.5
  • 17
    • 84861573124 scopus 로고    scopus 로고
    • Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease
    • Sullivan, S., Kirk, E.P., Mittendorfer, B., Patterson, B.W., Klein, S., Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease. Hepatology 55 (2012), 1738–1745.
    • (2012) Hepatology , vol.55 , pp. 1738-1745
    • Sullivan, S.1    Kirk, E.P.2    Mittendorfer, B.3    Patterson, B.W.4    Klein, S.5
  • 18
    • 70350072281 scopus 로고    scopus 로고
    • Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss
    • Johnson, N.A., Sachinwalla, T., Walton, D.W., Smith, K., Armstrong, A., Thompson, M.W., et al. Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Hepatology 50 (2009), 1105–1112.
    • (2009) Hepatology , vol.50 , pp. 1105-1112
    • Johnson, N.A.1    Sachinwalla, T.2    Walton, D.W.3    Smith, K.4    Armstrong, A.5    Thompson, M.W.6
  • 19
    • 84955259240 scopus 로고    scopus 로고
    • Exercise and diet in the management of nonalcoholic fatty liver disease
    • Mahady, S.E., George, J., Exercise and diet in the management of nonalcoholic fatty liver disease. Metabolism 65 (2016), 1172–1182.
    • (2016) Metabolism , vol.65 , pp. 1172-1182
    • Mahady, S.E.1    George, J.2
  • 20
    • 84952064157 scopus 로고    scopus 로고
    • Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial
    • Hallsworth, K., Thoma, C., Hollingsworth, K.G., Cassidy, S., Anstee, Q.M., Day, C.P., et al. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial. Clin Sci 129 (2015), 1097–1105.
    • (2015) Clin Sci , vol.129 , pp. 1097-1105
    • Hallsworth, K.1    Thoma, C.2    Hollingsworth, K.G.3    Cassidy, S.4    Anstee, Q.M.5    Day, C.P.6
  • 21
    • 84948419672 scopus 로고    scopus 로고
    • Aerobic interval exercise improves parameters of nonalcoholic fatty liver disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats
    • Kapravelou, G., Martinez, R., Andrade, A.M., Nebot, E., Camiletti-Moiron, D., Aparicio, V.A., et al. Aerobic interval exercise improves parameters of nonalcoholic fatty liver disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats. Appl Physiol Nutr Metab 40 (2015), 1242–1252.
    • (2015) Appl Physiol Nutr Metab , vol.40 , pp. 1242-1252
    • Kapravelou, G.1    Martinez, R.2    Andrade, A.M.3    Nebot, E.4    Camiletti-Moiron, D.5    Aparicio, V.A.6
  • 22
    • 84941345328 scopus 로고    scopus 로고
    • Effect of training intensity on nonalcoholic fatty liver disease
    • Cho, J., Kim, S., Lee, S., Kang, H., Effect of training intensity on nonalcoholic fatty liver disease. Med Sci Sports Exerc 47 (2015), 1624–1634.
    • (2015) Med Sci Sports Exerc , vol.47 , pp. 1624-1634
    • Cho, J.1    Kim, S.2    Lee, S.3    Kang, H.4
  • 24
    • 12144259379 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population
    • Szczepaniak, L.S., Nurenberg, P., Leonard, D., Browning, J.D., Reingold, J.S., Grundy, S., et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab 288 (2005), E462–8.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E462-8
    • Szczepaniak, L.S.1    Nurenberg, P.2    Leonard, D.3    Browning, J.D.4    Reingold, J.S.5    Grundy, S.6
  • 25
    • 84896690564 scopus 로고    scopus 로고
    • Short-term aerobic exercise training increases postprandial pancreatic polypeptide but not peptide YY concentrations in obese individuals
    • Kanaley, J.A., Heden, T.D., Liu, Y., Whaley-Connell, A.T., Chockalingam, A., Dellsperger, K.C., et al. Short-term aerobic exercise training increases postprandial pancreatic polypeptide but not peptide YY concentrations in obese individuals. Int J Obes (Lond) 38 (2014), 266–271.
    • (2014) Int J Obes (Lond) , vol.38 , pp. 266-271
    • Kanaley, J.A.1    Heden, T.D.2    Liu, Y.3    Whaley-Connell, A.T.4    Chockalingam, A.5    Dellsperger, K.C.6
  • 26
    • 84937847704 scopus 로고    scopus 로고
    • Prior exercise does not alter the incretin response to a subsequent meal in obese women
    • Nyhoff, L.M., Heden, T.D., Leidy, H.J., Winn, N.C., Park, Y.M., Thyfault, J.P., et al. Prior exercise does not alter the incretin response to a subsequent meal in obese women. Peptides 71 (2015), 94–99.
    • (2015) Peptides , vol.71 , pp. 94-99
    • Nyhoff, L.M.1    Heden, T.D.2    Leidy, H.J.3    Winn, N.C.4    Park, Y.M.5    Thyfault, J.P.6
  • 27
    • 8944256349 scopus 로고
    • New methods for calculating metabolic rate with special reference to protein metabolism
    • Weir, J.B., New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 109 (1949), 1–9.
    • (1949) J Physiol , vol.109 , pp. 1-9
    • Weir, J.B.1
  • 28
    • 17944365040 scopus 로고    scopus 로고
    • Abdominal fat distribution in pre- and postmenopausal women: the impact of physical activity, age, and menopausal status
    • Kanaley, J.A., Sames, C., Swisher, L., Swick, A.G., Ploutz-Snyder, L.L., Steppan, C.M., et al. Abdominal fat distribution in pre- and postmenopausal women: the impact of physical activity, age, and menopausal status. Metabolism 50 (2001), 976–982.
    • (2001) Metabolism , vol.50 , pp. 976-982
    • Kanaley, J.A.1    Sames, C.2    Swisher, L.3    Swick, A.G.4    Ploutz-Snyder, L.L.5    Steppan, C.M.6
  • 29
    • 0034989141 scopus 로고    scopus 로고
    • Java-based graphical user interface for the MRUI quantitation package
    • Naressi, A., Couturier, C., Devos, J.M., Janssen, M., Mangeat, C., de Beer, R., et al. Java-based graphical user interface for the MRUI quantitation package. MAGMA 12 (2001), 141–152.
    • (2001) MAGMA , vol.12 , pp. 141-152
    • Naressi, A.1    Couturier, C.2    Devos, J.M.3    Janssen, M.4    Mangeat, C.5    de Beer, R.6
  • 31
    • 84908374749 scopus 로고    scopus 로고
    • Determining pancreatic beta-cell compensation for changing insulin sensitivity using an oral glucose tolerance test
    • Solomon, T.P., Malin, S.K., Karstoft, K., Knudsen, S.H., Haus, J.M., Laye, M.J., et al. Determining pancreatic beta-cell compensation for changing insulin sensitivity using an oral glucose tolerance test. Am J Physiol Endocrinol Metab 307 (2014), E822–9.
    • (2014) Am J Physiol Endocrinol Metab , vol.307 , pp. E822-9
    • Solomon, T.P.1    Malin, S.K.2    Karstoft, K.3    Knudsen, S.H.4    Haus, J.M.5    Laye, M.J.6
  • 32
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews, D.R., Hosker, J.P., Rudenski, A.S., Naylor, B.A., Treacher, D.F., Turner, R.C., Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985), 412–419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 33
    • 84859942552 scopus 로고    scopus 로고
    • Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
    • Lomonaco, R., Ortiz-Lopez, C., Orsak, B., Webb, A., Hardies, J., Darland, C., et al. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. Hepatology 55 (2012), 1389–1397.
    • (2012) Hepatology , vol.55 , pp. 1389-1397
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3    Webb, A.4    Hardies, J.5    Darland, C.6
  • 34
    • 72449161164 scopus 로고    scopus 로고
    • Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults
    • Shah, K., Stufflebam, A., Hilton, T.N., Sinacore, D.R., Klein, S., Villareal, D.T., Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) 17 (2009), 2162–2168.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 2162-2168
    • Shah, K.1    Stufflebam, A.2    Hilton, T.N.3    Sinacore, D.R.4    Klein, S.5    Villareal, D.T.6
  • 35
    • 34447119267 scopus 로고    scopus 로고
    • Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism
    • Shojaee-Moradie, F., Baynes, K.C., Pentecost, C., Bell, J.D., Thomas, E.L., Jackson, N.C., et al. Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism. Diabetologia 50 (2007), 404–413.
    • (2007) Diabetologia , vol.50 , pp. 404-413
    • Shojaee-Moradie, F.1    Baynes, K.C.2    Pentecost, C.3    Bell, J.D.4    Thomas, E.L.5    Jackson, N.C.6
  • 36
    • 34548129160 scopus 로고    scopus 로고
    • Use of covariates in randomized controlled trials
    • Van Breukelen, G.J., Van Dijk, K.R., Use of covariates in randomized controlled trials. J Int Neuropsychol Soc 13 (2007), 903–904.
    • (2007) J Int Neuropsychol Soc , vol.13 , pp. 903-904
    • Van Breukelen, G.J.1    Van Dijk, K.R.2
  • 37
    • 85007277385 scopus 로고    scopus 로고
    • Effects of lifestyle interventions on clinical characteristics of patients with non-alcoholic fatty liver disease: a meta-analysis
    • Katsagoni, C.N., Georgoulis, M., Papatheodoridis, G.V., Panagiotakos, D.B., Kontogianni, M.D., Effects of lifestyle interventions on clinical characteristics of patients with non-alcoholic fatty liver disease: a meta-analysis. Metabolism 68 (2017), 119–132.
    • (2017) Metabolism , vol.68 , pp. 119-132
    • Katsagoni, C.N.1    Georgoulis, M.2    Papatheodoridis, G.V.3    Panagiotakos, D.B.4    Kontogianni, M.D.5
  • 38
    • 79952361224 scopus 로고    scopus 로고
    • Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease
    • [quiz 9]
    • Kistler, K.D., Brunt, E.M., Clark, J.M., Diehl, A.M., Sallis, J.F., Schwimmer, J.B., et al. Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. Am J Gastroenterol 106 (2011), 460–468 [quiz 9].
    • (2011) Am J Gastroenterol , vol.106 , pp. 460-468
    • Kistler, K.D.1    Brunt, E.M.2    Clark, J.M.3    Diehl, A.M.4    Sallis, J.F.5    Schwimmer, J.B.6
  • 39
    • 34548222136 scopus 로고    scopus 로고
    • Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association
    • Haskell, W.L., Lee, I.M., Pate, R.R., Powell, K.E., Blair, S.N., Franklin, B.A., et al. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation 116 (2007), 1081–1093.
    • (2007) Circulation , vol.116 , pp. 1081-1093
    • Haskell, W.L.1    Lee, I.M.2    Pate, R.R.3    Powell, K.E.4    Blair, S.N.5    Franklin, B.A.6
  • 41
    • 70449099399 scopus 로고    scopus 로고
    • Aerobic exercise increases peripheral and hepatic insulin sensitivity in sedentary adolescents
    • van der Heijden, G.J., Toffolo, G., Manesso, E., Sauer, P.J., Sunehag, A.L., Aerobic exercise increases peripheral and hepatic insulin sensitivity in sedentary adolescents. J Clin Endocrinol Metab 94 (2009), 4292–4299.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4292-4299
    • van der Heijden, G.J.1    Toffolo, G.2    Manesso, E.3    Sauer, P.J.4    Sunehag, A.L.5
  • 42
    • 73449116035 scopus 로고    scopus 로고
    • Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis
    • Promrat, K., Kleiner, D.E., Niemeier, H.M., Jackvony, E., Kearns, M., Wands, J.R., et al. Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis. Hepatology 51 (2010), 121–129.
    • (2010) Hepatology , vol.51 , pp. 121-129
    • Promrat, K.1    Kleiner, D.E.2    Niemeier, H.M.3    Jackvony, E.4    Kearns, M.5    Wands, J.R.6
  • 44
    • 84980357038 scopus 로고    scopus 로고
    • Effects of moderate and vigorous exercise on nonalcoholic fatty liver disease: a randomized clinical trial
    • Zhang, H.J., He, J., Pan, L.L., Ma, Z.M., Han, C.K., Chen, C.S., et al. Effects of moderate and vigorous exercise on nonalcoholic fatty liver disease: a randomized clinical trial. JAMA Intern Med 176 (2016), 1074–1082.
    • (2016) JAMA Intern Med , vol.176 , pp. 1074-1082
    • Zhang, H.J.1    He, J.2    Pan, L.L.3    Ma, Z.M.4    Han, C.K.5    Chen, C.S.6
  • 45
    • 84879979114 scopus 로고    scopus 로고
    • Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver disease
    • Haus, J.M., Solomon, T.P., Kelly, K.R., Fealy, C.E., Kullman, E.L., Scelsi, A.R., et al. Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver disease. J Clin Endocrinol Metab 98 (2013), E1181–8.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. E1181-8
    • Haus, J.M.1    Solomon, T.P.2    Kelly, K.R.3    Fealy, C.E.4    Kullman, E.L.5    Scelsi, A.R.6
  • 46
    • 84863307348 scopus 로고    scopus 로고
    • Short-term exercise reduces markers of hepatocyte apoptosis in nonalcoholic fatty liver disease
    • Fealy, C.E., Haus, J.M., Solomon, T.P., Pagadala, M., Flask, C.A., McCullough, A.J., et al. Short-term exercise reduces markers of hepatocyte apoptosis in nonalcoholic fatty liver disease. J Appl Physiol 113 (2012), 1–6.
    • (2012) J Appl Physiol , vol.113 , pp. 1-6
    • Fealy, C.E.1    Haus, J.M.2    Solomon, T.P.3    Pagadala, M.4    Flask, C.A.5    McCullough, A.J.6
  • 48
    • 84885230287 scopus 로고    scopus 로고
    • Fetuin-A is linked to improved glucose tolerance after short-term exercise training in nonalcoholic fatty liver disease
    • Malin, S.K., Mulya, A., Fealy, C.E., Haus, J.M., Pagadala, M.R., Scelsi, A.R., et al. Fetuin-A is linked to improved glucose tolerance after short-term exercise training in nonalcoholic fatty liver disease. J Appl Physiol 115 (2013), 988–994.
    • (2013) J Appl Physiol , vol.115 , pp. 988-994
    • Malin, S.K.1    Mulya, A.2    Fealy, C.E.3    Haus, J.M.4    Pagadala, M.R.5    Scelsi, A.R.6
  • 49
    • 33746367157 scopus 로고    scopus 로고
    • Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans
    • Stefan, N., Hennige, A.M., Staiger, H., Machann, J., Schick, F., Krober, S.M., et al. Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans. Diabetes Care 29 (2006), 853–857.
    • (2006) Diabetes Care , vol.29 , pp. 853-857
    • Stefan, N.1    Hennige, A.M.2    Staiger, H.3    Machann, J.4    Schick, F.5    Krober, S.M.6
  • 50
    • 84952043139 scopus 로고    scopus 로고
    • Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease
    • Cuthbertson, D.J., Shojaee-Moradie, F., Sprung, V.S., Jones, H., Pugh, C.J., Richardson, P., et al. Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease. Clin Sci (Lond) 130 (2016), 93–104.
    • (2016) Clin Sci (Lond) , vol.130 , pp. 93-104
    • Cuthbertson, D.J.1    Shojaee-Moradie, F.2    Sprung, V.S.3    Jones, H.4    Pugh, C.J.5    Richardson, P.6
  • 51
    • 85001850052 scopus 로고    scopus 로고
    • Exercise reduces liver lipids and visceral adiposity in patients with nonalcoholic steatohepatitis in a randomized controlled trial
    • [e3]
    • Houghton, D., Thoma, C., Hallsworth, K., Cassidy, S., Hardy, T., Burt, A.D., et al. Exercise reduces liver lipids and visceral adiposity in patients with nonalcoholic steatohepatitis in a randomized controlled trial. Clin Gastroenterol Hepatol 15 (2017), 96–102 [e3].
    • (2017) Clin Gastroenterol Hepatol , vol.15 , pp. 96-102
    • Houghton, D.1    Thoma, C.2    Hallsworth, K.3    Cassidy, S.4    Hardy, T.5    Burt, A.D.6
  • 52
    • 85008873207 scopus 로고    scopus 로고
    • Insights into the role and interdependence of oxidative stress and inflammation in liver diseases
    • Li, S., Hong, M., Tan, H.Y., Wang, N., Feng, Y., Insights into the role and interdependence of oxidative stress and inflammation in liver diseases. Oxid Med Cell Longev, 2016, 2016, 4234061.
    • (2016) Oxid Med Cell Longev , vol.2016 , pp. 4234061
    • Li, S.1    Hong, M.2    Tan, H.Y.3    Wang, N.4    Feng, Y.5
  • 54
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly, K.L., Smith, C.I., Schwarzenberg, S.J., Jessurun, J., Boldt, M.D., Parks, E.J., Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115 (2005), 1343–1351.
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 55
    • 34547911800 scopus 로고    scopus 로고
    • The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
    • Petersen, K.F., Dufour, S., Savage, D.B., Bilz, S., Solomon, G., Yonemitsu, S., et al. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A 104 (2007), 12587–12594.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12587-12594
    • Petersen, K.F.1    Dufour, S.2    Savage, D.B.3    Bilz, S.4    Solomon, G.5    Yonemitsu, S.6
  • 56
    • 80051971972 scopus 로고    scopus 로고
    • Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals
    • Rabol, R., Petersen, K.F., Dufour, S., Flannery, C., Shulman, G.I., Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals. Proc Natl Acad Sci U S A 108 (2011), 13705–13709.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13705-13709
    • Rabol, R.1    Petersen, K.F.2    Dufour, S.3    Flannery, C.4    Shulman, G.I.5
  • 57
    • 85008222802 scopus 로고    scopus 로고
    • Mitochondrial adaptation in nonalcoholic fatty liver disease: novel mechanisms and treatment strategies
    • Sunny, N.E., Bril, F., Cusi, K., Mitochondrial adaptation in nonalcoholic fatty liver disease: novel mechanisms and treatment strategies. Trends Endocrinol Metab 28 (2017), 250–260.
    • (2017) Trends Endocrinol Metab , vol.28 , pp. 250-260
    • Sunny, N.E.1    Bril, F.2    Cusi, K.3


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