Determining pancreatic β-cell compensation for changing insulin sensitivity using an oral glucose tolerance test

American Journal of Physiology - Endocrinology and Metabolism

Volumn 307, Issue 9, 2014, Pages E822-E829

  Solomon, Thomas P J ^a,b   Malin, Steven K ^c   Karstoft, Kristian ^b   Knudsen, Sine H ^b   Haus, Jacob M ^d   Laye, Matthew J ^b   Pedersen, Maria ^b   Pedersen, Bente K ^b   Kirwan, John P ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Rigshospitalet   (Denmark)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Disposition index; Hyperinsulinemic euglycemic clamp; Insulin resistance; Insulin secretion; Insulin sensitivity; Insulin sensitivity index; Obesity; Oral glucose tolerance; Type 2 diabetes; cell dysfunction; cell function

Indexed keywords

C PEPTIDE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLUCAGON LIKE PEPTIDE 1; INSULIN; METFORMIN; SULFONYLUREA; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN;

ADULT; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CLAMP; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INDEPENDENT VARIABLE; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OBSERVATIONAL STUDY; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; ALLOSTASIS; ANALYSIS; BLOOD; CLINICAL TRIAL; COHORT ANALYSIS; DENMARK; DIABETES MELLITUS, TYPE 2; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; METABOLISM; MIDDLE AGED; MULTICENTER STUDY; OHIO; PATHOPHYSIOLOGY; PREDIABETIC STATE; SECRETION (PROCESS); VALIDATION STUDY;

ALLOSTASIS; BLOOD GLUCOSE; COHORT STUDIES; DENMARK; DIABETES MELLITUS, TYPE 2; DIAGNOSIS, DIFFERENTIAL; DISEASE PROGRESSION; FEMALE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; OHIO; PREDIABETIC STATE;

EID: 84908374749     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00269.2014     Document Type: Article

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