Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses

Cell Host and Microbe

Volumn 22, Issue 5, 2017, Pages 653-666.e5

  Liu, Haiyun ^a   Archer, Nathan K ^a   Dillen, Carly A ^a   Wang, Yu ^a   Ashbaugh, Alyssa G ^a   Ortines, Roger V ^a   Kao, Tracy ^a   Lee, Steven K ^a   Cai, Shuting S ^a   Miller, Robert J ^a   Marchitto, Mark C ^a   Zhang, Emily ^a   Riggins, Daniel P ^c   Plaut, Roger D ^c   Stibitz, Scott ^c   Geha, Raif S ^d   Miller, Lloyd S ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

atopic dermatitis; cutaneous; epicutaneous; IL 17; IL 36; inflammation; phenol soluble modulin; skin; Staphylococcus aureus; T cell

Indexed keywords

CD4 ANTIGEN; CYTOKINE RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 35; INTERLEUKIN 36; INTERLEUKIN 36 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; UNCLASSIFIED DRUG; BACTERIAL TOXIN; CYTOKINE; HEMOLYSIN; IL33 PROTEIN, MOUSE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN-36 RECEPTOR, MOUSE; INTERLEUKIN-36, MOUSE; MYD88 PROTEIN, MOUSE; STAPHYLOCOCCAL ALPHA-TOXIN; STAPHYLOCOCCAL DELTA TOXIN; VIRULENCE FACTOR;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; GAMMA DELTA T LYMPHOCYTE; HOST RESISTANCE; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE; ANIMAL; ATOPIC DERMATITIS; BAGG ALBINO MOUSE; DISEASE MODEL; FEMALE; HOST PARASITE INTERACTION; IMMUNOLOGY; INFLAMMATION; MALE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; SKIN; STAPHYLOCOCCUS INFECTION;

ANIMALS; BACTERIAL TOXINS; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DERMATITIS, ATOPIC; DISEASE MODELS, ANIMAL; FEMALE; HEMOLYSIN PROTEINS; HOST-PARASITE INTERACTIONS; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-17; INTERLEUKIN-18; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; INTERLEUKIN-33; MALE; MICE; MICE, INBRED BALB C; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, INTERLEUKIN-1; SKIN; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; T-LYMPHOCYTES; VIRULENCE FACTORS;

EID: 85032733103     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.10.006     Document Type: Article

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