메뉴 건너뛰기




Volumn 18, Issue 1, 2017, Pages

Ghrelin therapy improves lung and cardiovascular function in experimental emphysema

Author keywords

Cardiac function; Experimental emphysema; Ghrelin therapy; Lung function; Lung inflammation; Lung remodelling

Indexed keywords

GHRELIN; INTERLEUKIN 10; INTERLEUKIN 8; KERATINOCYTE DERIVED CHEMOKINE; PANCREATIC ELASTASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

EID: 85032729395     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-017-0668-9     Document Type: Article
Times cited : (17)

References (63)
  • 2
    • 0021919760 scopus 로고
    • Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis
    • Janoff A. Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis. 1985;132:417-33.
    • (1985) Am Rev Respir Dis. , vol.132 , pp. 417-433
    • Janoff, A.1
  • 3
    • 0041374156 scopus 로고    scopus 로고
    • On the progressive nature of emphysema: roles of proteases, inflammation, and mechanical forces
    • Suki B, Lutchen KR, Ingenito EP. On the progressive nature of emphysema: roles of proteases, inflammation, and mechanical forces. Am J Respir Crit Care Med. 2003;168:516-21.
    • (2003) Am J Respir Crit Care Med. , vol.168 , pp. 516-521
    • Suki, B.1    Lutchen, K.R.2    Ingenito, E.P.3
  • 5
    • 84884546447 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and cardiovascular disease
    • Bhatt SP, Dransfield MT. Chronic obstructive pulmonary disease and cardiovascular disease. Trans Res. 2013;162:237-51.
    • (2013) Trans Res. , vol.162 , pp. 237-251
    • Bhatt, S.P.1    Dransfield, M.T.2
  • 8
    • 85000797861 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and malnutrition in developing countries
    • Sehgal IS, Dhooria S, Agarwal R. Chronic obstructive pulmonary disease and malnutrition in developing countries. Curr Opin Pulm Med. 2017;23:139-48.
    • (2017) Curr Opin Pulm Med , vol.23 , pp. 139-148
    • Sehgal, I.S.1    Dhooria, S.2    Agarwal, R.3
  • 9
    • 79952041715 scopus 로고    scopus 로고
    • Ghrelin cells in the gastrointestinal tract
    • Sakata I, Sakai T. Ghrelin cells in the gastrointestinal tract. Int J Pept. 2010;2010
    • (2010) Int J Pept. , pp. 2010
    • Sakata, I.1    Sakai, T.2
  • 10
    • 79958082780 scopus 로고    scopus 로고
    • The effects of ghrelin on inflammation and the immune system
    • Baatar D, Patel K, Taub DD. The effects of ghrelin on inflammation and the immune system. Mol Cell Endocrinol. 2011;340:44-58.
    • (2011) Mol Cell Endocrinol. , vol.340 , pp. 44-58
    • Baatar, D.1    Patel, K.2    Taub, D.D.3
  • 11
    • 49549084818 scopus 로고    scopus 로고
    • Gut hormones and the treatment of disease cachexia
    • Ashby D, Choi P, Bloom S. Gut hormones and the treatment of disease cachexia. Proc Nutr Soc. 2008;67:263-9.
    • (2008) Proc Nutr Soc. , vol.67 , pp. 263-269
    • Ashby, D.1    Choi, P.2    Bloom, S.3
  • 12
    • 79958134198 scopus 로고    scopus 로고
    • Ghrelin and cachexia: will treatment with GHSR-1a agonists make a difference for patients suffering from chronic wasting syndromes?
    • DeBoer MD. Ghrelin and cachexia: will treatment with GHSR-1a agonists make a difference for patients suffering from chronic wasting syndromes? Mol Cell Endocrinol. 2011;340:97-105.
    • (2011) Mol Cell Endocrinol. , vol.340 , pp. 97-105
    • DeBoer, M.D.1
  • 17
    • 84860454868 scopus 로고    scopus 로고
    • Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial
    • Miki K, Maekura R, Nagaya N, Nakazato M, Kimura H, Murakami S, Ohnishi S, Hiraga T, Miki M, Kitada S, et al. Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial. PLoS One. 2012;7:e35708.
    • (2012) PLoS One. , vol.7
    • Miki, K.1    Maekura, R.2    Nagaya, N.3    Nakazato, M.4    Kimura, H.5    Murakami, S.6    Ohnishi, S.7    Hiraga, T.8    Miki, M.9    Kitada, S.10
  • 18
    • 84878724206 scopus 로고    scopus 로고
    • Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment
    • Miki K, Maekura R, Nagaya N, Kitada S, Miki M, Yoshimura K, Tateishi Y, Motone M, Hiraga T, Mori M, Kangawa K. Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment. BMC Pulm Med. 2013;13:37.
    • (2013) BMC Pulm Med. , vol.13 , pp. 37
    • Miki, K.1    Maekura, R.2    Nagaya, N.3    Kitada, S.4    Miki, M.5    Yoshimura, K.6    Tateishi, Y.7    Motone, M.8    Hiraga, T.9    Mori, M.10    Kangawa, K.11
  • 20
    • 84925374854 scopus 로고    scopus 로고
    • Ghrelin ameliorates catabolic conditions and respiratory dysfunction in a chronic obstructive pulmonary disease model of chronic cigarette smoke-exposed rats
    • Kamiide Y, Inomata N, Furuya M, Yada T. Ghrelin ameliorates catabolic conditions and respiratory dysfunction in a chronic obstructive pulmonary disease model of chronic cigarette smoke-exposed rats. Eur J Pharmacol. 2015;755:88-94.
    • (2015) Eur J Pharmacol. , vol.755 , pp. 88-94
    • Kamiide, Y.1    Inomata, N.2    Furuya, M.3    Yada, T.4
  • 21
    • 85041813459 scopus 로고    scopus 로고
    • Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research
    • Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol. 2010;8:e1000412.
    • (2010) PLoS Biol. , vol.8
    • Kilkenny, C.1    Browne, W.J.2    Cuthill, I.C.3    Emerson, M.4    Altman, D.G.5
  • 24
    • 84925515752 scopus 로고    scopus 로고
    • Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging
    • Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28:1-39. e14
    • (2015) J Am Soc Echocardiogr. , vol.28 , pp. 1-39
    • Lang, R.M.1    Badano, L.P.2    Mor-Avi, V.3    Afilalo, J.4    Armstrong, A.5    Ernande, L.6    Flachskampf, F.A.7    Foster, E.8    Goldstein, S.A.9    Kuznetsova, T.10
  • 25
    • 0022256369 scopus 로고
    • Analysis of the behavior of the respiratory system with constant inspiratory flow
    • Bates JH, Rossi A, Milic-Emili J. Analysis of the behavior of the respiratory system with constant inspiratory flow. J Appl Physiol. 1985;58:1840-8.
    • (1985) J Appl Physiol. , vol.58 , pp. 1840-1848
    • Bates, J.H.1    Rossi, A.2    Milic-Emili, J.3
  • 28
    • 0025217533 scopus 로고
    • Recent stereological methods for cell biology: a brief survey
    • Cruz-Orive LM, Weibel ER. Recent stereological methods for cell biology: a brief survey. Am J Physiol. 1990;258:L148-56.
    • (1990) Am J Physiol. , vol.258 , pp. L148-L156
    • Cruz-Orive, L.M.1    Weibel, E.R.2
  • 30
    • 0034581319 scopus 로고    scopus 로고
    • Surfactant protein-D and pulmonary host defense
    • Crouch EC. Surfactant protein-D and pulmonary host defense. Respir Res. 2000;1:93-108.
    • (2000) Respir Res. , vol.1 , pp. 93-108
    • Crouch, E.C.1
  • 33
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest. 2012;122:787-95.
    • (2012) J Clin Invest. , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 35
    • 85021955636 scopus 로고    scopus 로고
    • Mechanisms of the alternative activation of macrophages and non-coding RNAs in the development of radiation-induced lung fibrosis
    • Duru N, Wolfson B, Zhou Q. Mechanisms of the alternative activation of macrophages and non-coding RNAs in the development of radiation-induced lung fibrosis. World J Biol Chem. 2016;7:231-9.
    • (2016) World J Biol Chem. , vol.7 , pp. 231-239
    • Duru, N.1    Wolfson, B.2    Zhou, Q.3
  • 36
    • 82855179388 scopus 로고    scopus 로고
    • Elastase-induced pulmonary emphysema: insights from experimental models
    • Antunes MA, Rocco PR. Elastase-induced pulmonary emphysema: insights from experimental models. An Acad Bras Cienc. 2011;83:1385-96.
    • (2011) An Acad Bras Cienc. , vol.83 , pp. 1385-1396
    • Antunes, M.A.1    Rocco, P.R.2
  • 42
    • 84863011263 scopus 로고    scopus 로고
    • Cigarette smoking and inflammation: cellular and molecular mechanisms
    • Lee J, Taneja V, Vassallo R. Cigarette smoking and inflammation: cellular and molecular mechanisms. J Dent Res. 2012;91:142-9.
    • (2012) J Dent Res. , vol.91 , pp. 142-149
    • Lee, J.1    Taneja, V.2    Vassallo, R.3
  • 45
    • 47849121225 scopus 로고    scopus 로고
    • Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?
    • Trayhurn P, Wang B, Wood IS. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr. 2008;100:227-35.
    • (2008) Br J Nutr. , vol.100 , pp. 227-235
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 47
    • 84899951603 scopus 로고    scopus 로고
    • Serum ghrelin and adiponectin levels are increased but serum leptin level is unchanged in low weight Chronic Obstructive Pulmonary Disease patients
    • Uzum AK, Aydin MM, Tutuncu Y, Omer B, Kiyan E, Alagol F. Serum ghrelin and adiponectin levels are increased but serum leptin level is unchanged in low weight Chronic Obstructive Pulmonary Disease patients. Eur J Intern Med. 2014;25:364-9.
    • (2014) Eur J Intern Med. , vol.25 , pp. 364-369
    • Uzum, A.K.1    Aydin, M.M.2    Tutuncu, Y.3    Omer, B.4    Kiyan, E.5    Alagol, F.6
  • 48
    • 50849133889 scopus 로고    scopus 로고
    • Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection
    • Kodama T, Ashitani J, Matsumoto N, Kangawa K, Nakazato M. Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection. Pulm Pharmacol Ther. 2008;21:774-9.
    • (2008) Pulm Pharmacol Ther. , vol.21 , pp. 774-779
    • Kodama, T.1    Ashitani, J.2    Matsumoto, N.3    Kangawa, K.4    Nakazato, M.5
  • 49
    • 84860351762 scopus 로고    scopus 로고
    • One dose of ghrelin prevents the acute and sustained increase in cardiac sympathetic tone after myocardial infarction
    • Schwenke DO, Tokudome T, Kishimoto I, Horio T, Cragg PA, Shirai M, Kangawa K. One dose of ghrelin prevents the acute and sustained increase in cardiac sympathetic tone after myocardial infarction. Endocrinology. 2012;153:2436-43.
    • (2012) Endocrinology , vol.153 , pp. 2436-2443
    • Schwenke, D.O.1    Tokudome, T.2    Kishimoto, I.3    Horio, T.4    Cragg, P.A.5    Shirai, M.6    Kangawa, K.7
  • 52
    • 9644252634 scopus 로고    scopus 로고
    • Characterization of a population of small macrophages in induced sputum of patients with chronic obstructive pulmonary disease and healthy volunteers
    • Frankenberger M, Menzel M, Betz R, Kassner G, Weber N, Kohlhaufl M, Haussinger K, Ziegler-Heitbrock L. Characterization of a population of small macrophages in induced sputum of patients with chronic obstructive pulmonary disease and healthy volunteers. Clin Exp Immunol. 2004;138:507-16.
    • (2004) Clin Exp Immunol , vol.138 , pp. 507-516
    • Frankenberger, M.1    Menzel, M.2    Betz, R.3    Kassner, G.4    Weber, N.5    Kohlhaufl, M.6    Haussinger, K.7    Ziegler-Heitbrock, L.8
  • 53
  • 54
    • 55849148482 scopus 로고    scopus 로고
    • The cytokine network in asthma and chronic obstructive pulmonary disease
    • Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest. 2008;118:3546-56.
    • (2008) J Clin Invest. , vol.118 , pp. 3546-3556
    • Barnes, P.J.1
  • 60
    • 84941336987 scopus 로고    scopus 로고
    • Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-beta1 Expression and Autophagy
    • Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X. Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-beta1 Expression and Autophagy. Int J Mol Sci. 2015;16:21911-30.
    • (2015) Int J Mol Sci. , vol.16 , pp. 21911-21930
    • Mao, Y.1    Zhang, S.2    Yu, F.3    Li, H.4    Guo, C.5    Fan, X.6
  • 61
    • 84897556094 scopus 로고    scopus 로고
    • The M1 and M2 paradigm of macrophage activation: time for reassessment
    • Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000prime Rep. 2014;6:13.
    • (2014) F1000prime Rep. , vol.6 , pp. 13
    • Martinez, F.O.1    Gordon, S.2
  • 63
    • 84873624759 scopus 로고    scopus 로고
    • The role of collagen synthesis in ventricular and vascular adaptation to hypoxic pulmonary hypertension
    • Schreier D, Hacker T, Song G, Chesler N. The role of collagen synthesis in ventricular and vascular adaptation to hypoxic pulmonary hypertension. J Biomech Eng. 2013;135:021018.
    • (2013) J Biomech Eng. , vol.135
    • Schreier, D.1    Hacker, T.2    Song, G.3    Chesler, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.