Therapeutic effects of LASSBio-596 in an elastase-induced mouse model of emphysema

Frontiers in Physiology

Volumn 6, Issue SEP, 2015, Pages

  Padilha, Gisele A ^a   Henriques, Isabela ^a   Lopes Pacheco, Miquéias ^a   Abreu, Soraia C ^a   Oliveira, Milena V ^a   Morales, Marcelo M ^a   Lima, Lidia M ^a   Barreiro, Eliezer J ^a   Silva, Pedro L ^a   Xisto, Debora G ^a   Rocco, Patricia R M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Elastic fiber; Emphysema; Inflammation; Macrophage; Remodeling

Indexed keywords

BENZOIC ACID DERIVATIVE; DIMETHYL SULFOXIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LASSBIO 596; PANCREATIC ELASTASE; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLLAGEN FIBER; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ELASTASE-INDUCED EMPHYSEMA; ELASTIC FIBER; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; HYPERINFLATION; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; LUNG ALVEOLUS MACROPHAGE; LUNG COMPLIANCE; LUNG EMPHYSEMA; LUNG FUNCTION; LUNG MECHANICS; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TREATMENT DURATION;

EID: 84944753378     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2015.00267     Document Type: Article

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