-
1
-
-
85029416676
-
-
Accessed Revised 2013
-
Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease (2013). Accessed Revised 2013
-
(2013)
-
-
-
2
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
Mathers CD, Loncar D (2006) Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3 (11):e442. doi:10.1371/journal.pmed.0030442
-
(2006)
Plos Med
, vol.3
, Issue.11
-
-
Mathers, C.D.1
Loncar, D.2
-
3
-
-
1242343871
-
Alpha1-antitrypsin deficiency. 1: Epidemiology of alpha1-antitrypsin deficiency
-
Luisetti M, Seersholm N (2004) Alpha1-antitrypsin deficiency. 1: epidemiology of alpha1-antitrypsin deficiency. Thorax 59 (2):164-169
-
(2004)
Thorax
, vol.59
, Issue.2
, pp. 164-169
-
-
Luisetti, M.1
Seersholm, N.2
-
4
-
-
17644363337
-
Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema
-
Cantor JO, Cerreta JM, Ochoa M, Ma S, Chow T, Grunig G, Turino GM (2005) Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema. Exp Lung Res 31 (4):417-430
-
(2005)
Exp Lung Res
, vol.31
, Issue.4
, pp. 417-430
-
-
Cantor, J.O.1
Cerreta, J.M.2
Ochoa, M.3
Ma, S.4
Chow, T.5
Grunig, G.6
Turino, G.M.7
-
5
-
-
0029015850
-
Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population
-
de Santi MM, Martorana PA, Cavarra E, Lun-garella G (1995) Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population. Lab Investig 73(1):40-47
-
(1995)
Lab Investig
, vol.73
, Issue.1
, pp. 40-47
-
-
De Santi, M.M.1
Martorana, P.A.2
Cavarra, E.3
Lun-Garella, G.4
-
6
-
-
0017170881
-
Emphysema-like changes in the lungs of the blotchy mouse
-
Fisk DE, Kuhn C (1976) Emphysema-like changes in the lungs of the blotchy mouse. Am Rev Respir Dis 113(6):787-797
-
(1976)
Am Rev Respir Dis
, vol.113
, Issue.6
, pp. 787-797
-
-
Fisk, D.E.1
Kuhn, C.2
-
7
-
-
22044432275
-
Structural emphysema does not correlate with lung compliance: Lessons from the mouse smoking model
-
Foronjy RF, Mercer BA, Maxfield MW, Powell CA, D’Armiento J, Okada Y (2005) Structural emphysema does not correlate with lung compliance: lessons from the mouse smoking model. Exp Lung Res 31(6):547-562
-
(2005)
Exp Lung Res
, vol.31
, Issue.6
, pp. 547-562
-
-
Foronjy, R.F.1
Mercer, B.A.2
Maxfield, M.W.3
Powell, C.A.4
D’armiento, J.5
Okada, Y.6
-
8
-
-
0026741495
-
Lung collagen synthesis and deposition in tight-skin mice with genetic emphysema
-
Gardi C, Martorana PA, Calzoni P, van Even P, de Santi MM, Cavarra E, Lungarella G (1992) Lung collagen synthesis and deposition in tight-skin mice with genetic emphysema. Exp Mol Pathol 56(2):163-172
-
(1992)
Exp Mol Pathol
, vol.56
, Issue.2
, pp. 163-172
-
-
Gardi, C.1
Martorana, P.A.2
Calzoni, P.3
Van Even, P.4
De Santi, M.M.5
Cavarra, E.6
Lungarella, G.7
-
9
-
-
80052528898
-
Structure-function relations in an elastase-induced mouse model of emphysema
-
2010-0473OC [pii]
-
Hamakawa H, Bartolak-Suki E, Parameswaran H, Majumdar A, Lutchen KR, Suki B (2011) Structure-function relations in an elastase-induced mouse model of emphysema. Am J Respir Cell Mol Biol. doi:10.1165/rcmb.2010-0473OC. 2010-0473OC [pii]
-
(2011)
Am J Respir Cell Mol Biol
-
-
Hamakawa, H.1
Bartolak-Suki, E.2
Parameswaran, H.3
Majumdar, A.4
Lutchen, K.R.5
Suki, B.6
-
10
-
-
0242467574
-
Collagen phagocytosis by lung alveolar macrophages in animal models of emphysema
-
Lucattelli M, Cavarra E, de Santi MM, Tetley TD, Martorana PA, Lungarella G (2003) Collagen phagocytosis by lung alveolar macrophages in animal models of emphysema. Eur Respir J 22(5):728-734
-
(2003)
Eur Respir J
, vol.22
, Issue.5
, pp. 728-734
-
-
Lucattelli, M.1
Cavarra, E.2
De Santi, M.M.3
Tetley, T.D.4
Martorana, P.A.5
Lungarella, G.6
-
11
-
-
0032764331
-
Ultrastructure of lung elastin and collagen in mouse models of spontaneous emphysema
-
O’Donnell MD, O’Connor CM, FitzGerald MX, Lungarella G, Cavarra E, Martorana PA (1999) Ultrastructure of lung elastin and collagen in mouse models of spontaneous emphysema. Matrix Biol 18(4):357-360
-
(1999)
Matrix Biol
, vol.18
, Issue.4
, pp. 357-360
-
-
O’donnell, M.D.1
O’connor, C.M.2
Fitzgerald, M.X.3
Lungarella, G.4
Cavarra, E.5
Martorana, P.A.6
-
12
-
-
0037216547
-
Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1
-
Shiomi T, Okada Y, Foronjy R, Schiltz J, Jaen-ish R, Krane S, D’Armiento J (2003) Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1. Exp Lung Res 29(1):1-15
-
(2003)
Exp Lung Res
, vol.29
, Issue.1
, pp. 1-15
-
-
Shiomi, T.1
Okada, Y.2
Foronjy, R.3
Schiltz, J.4
Jaen-Ish, R.5
Krane, S.6
D’armiento, J.7
-
13
-
-
77957273815
-
Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM
-
Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I (2010) Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM. Proc Natl Acad Sci U S A 107(35):15571-15576. doi:10.1073/pnas.1007625107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.35
, pp. 15571-15576
-
-
Yao, H.1
Arunachalam, G.2
Hwang, J.W.3
Chung, S.4
Sundar, I.K.5
Kinnula, V.L.6
Crapo, J.D.7
Rahman, I.8
-
14
-
-
84907510672
-
Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema
-
Antunes MA, Abreu SC, Cruz FF, Teixeira AC, Lopes-Pacheco M, Bandeira E, Olsen PC, Diaz BL, Takyia CM, Freitas IP, Rocha NN, Cape-lozzi VL, Xisto DG, Weiss DJ, Morales MM, Rocco PR (2014) Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema. Respir Res 15:118. doi:10.1186/s12931-014-0118-x
-
(2014)
Respir Res
, vol.15
, pp. 118
-
-
Antunes, M.A.1
Abreu, S.C.2
Cruz, F.F.3
Teixeira, A.C.4
Lopes-Pacheco, M.5
Bandeira, E.6
Olsen, P.C.7
Diaz, B.L.8
Takyia, C.M.9
Freitas, I.P.10
Rocha, N.N.11
Cape-Lozzi, V.L.12
Xisto, D.G.13
Weiss, D.J.14
Morales, M.M.15
Rocco, P.R.16
-
15
-
-
84861670869
-
Protective effects of bone marrow mononuclear cell therapy on lung and heart in an elastase-induced emphysema model
-
Cruz FF, Antunes MA, Abreu SC, Fujisaki LC, Silva JD, Xisto DG, Maron-Gutierrez T, Ornellas DS, Sa VK, Rocha NN, Capelozzi VL, Morales MM, Rocco PR (2012) Protective effects of bone marrow mononuclear cell therapy on lung and heart in an elastase-induced emphysema model. Respir Physiol Neurobiol 182 (1):26-36. doi:10.1016/j.resp.2012.01.002
-
(2012)
Respir Physiol Neurobiol
, vol.182
, Issue.1
, pp. 26-36
-
-
Cruz, F.F.1
Antunes, M.A.2
Abreu, S.C.3
Fujisaki, L.C.4
Silva, J.D.5
Xisto, D.G.6
Maron-Gutierrez, T.7
Ornellas, D.S.8
Sa, V.K.9
Rocha, N.N.10
Capelozzi, V.L.11
Morales, M.M.12
Rocco, P.R.13
-
16
-
-
77953254345
-
Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice
-
Bracke KR, Dentener MA, Papakonstantinou E, Vernooy JH, Demoor T, Pauwels NS, Cleut-jens J, van Suylen RJ, Joos GF, Brusselle GG, Wouters EF (2010) Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice. Am J Respir Cell Mol Biol 42(6):753-761. doi:10.1165/rcmb.2008-0424OC
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, Issue.6
, pp. 753-761
-
-
Bracke, K.R.1
Dentener, M.A.2
Papakonstantinou, E.3
Vernooy, J.H.4
Demoor, T.5
Pauwels, N.S.6
Cleut-Jens, J.7
Van Suylen, R.J.8
Joos, G.F.9
Brusselle, G.G.10
Wouters, E.F.11
-
17
-
-
0035446905
-
Effects of cigarette smoke in mice with different levels of alpha (1)-proteinase inhibitor and sensitivity to oxidants
-
Cavarra E, Bartalesi B, Lucattelli M, Fineschi S, Lunghi B, Gambelli F, Ortiz LA, Martorana PA, Lungarella G (2001) Effects of cigarette smoke in mice with different levels of alpha (1)-proteinase inhibitor and sensitivity to oxidants. Am J Respir Crit Care Med 164 (5):886-890. doi:10.1164/ajrccm.164.5.2010032
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.5
, pp. 886-890
-
-
Cavarra, E.1
Bartalesi, B.2
Lucattelli, M.3
Fineschi, S.4
Lunghi, B.5
Gambelli, F.6
Ortiz, L.A.7
Martorana, P.A.8
Lungarella, G.9
-
18
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD (1997) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277 (5334):2002-2004
-
(1997)
Science
, vol.277
, Issue.5334
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
19
-
-
20644440194
-
Time course of neutrophil and macrophage elastino-lytic activities in cigarette smoke-induced emphysema
-
Pt 1
-
Ofulue AF, Ko M, Abboud RT (1998) Time course of neutrophil and macrophage elastino-lytic activities in cigarette smoke-induced emphysema. Am J Phys 275(6 Pt 1): L1134-L1144
-
(1998)
Am J Phys
, vol.275
, Issue.6
, pp. L1134-L1144
-
-
Ofulue, A.F.1
Ko, M.2
Abboud, R.T.3
-
20
-
-
0027461110
-
The pallid mouse. A model of genetic alpha 1-antitrypsin deficiency
-
Martorana PA, Brand T, Gardi C, van Even P, de Santi MM, Calzoni P, Marcolongo P, Lun-garella G (1993) The pallid mouse. A model of genetic alpha 1-antitrypsin deficiency. Lab Investig 68(2):233-241
-
(1993)
Lab Investig
, vol.68
, Issue.2
, pp. 233-241
-
-
Martorana, P.A.1
Brand, T.2
Gardi, C.3
Van Even, P.4
De Santi, M.M.5
Calzoni, P.6
Marcolongo, P.7
Lun-Garella, G.8
-
21
-
-
57349198004
-
Lung volumes and respiratory mechanics in elastase-induced emphysema in mice
-
[pii]
-
Hantos Z, Adamicza A, Janosi TZ, Szabari MV, Tolnai J, Suki B (2008) Lung volumes and respiratory mechanics in elastase-induced emphysema in mice. J Appl Physiol 105 (6):1864-1872. doi:10.1152/japplphysiol.90924.2008.90924.2008 [pii]
-
(2008)
J Appl Physiol
, vol.105
, Issue.6
, pp. 1864-1872
-
-
Hantos, Z.1
Adamicza, A.2
Janosi, T.Z.3
Szabari, M.V.4
Tolnai, J.5
Suki, B.6
-
22
-
-
12344321930
-
Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: Possible role of collagen remodeling
-
Ito S, Ingenito EP, Brewer KK, Black LD, Parameswaran H, Lutchen KR, Suki B (2005) Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling. J Appl Physiol 98:503-511
-
(2005)
J Appl Physiol
, vol.98
, pp. 503-511
-
-
Ito, S.1
Ingenito, E.P.2
Brewer, K.K.3
Black, L.D.4
Parameswaran, H.5
Lutchen, K.R.6
Suki, B.7
-
23
-
-
34547864628
-
The Fas/Fasligand pathway does not mediate the apoptosis in elastase-induced emphysema in mice
-
Sawada M, Ohno Y, La BL, Funaguchi N, Asai T, Yuhgetsu H, Takemura G, Minatoguchi S, Fujiwara H, Fujiwara T (2007) The Fas/Fasligand pathway does not mediate the apoptosis in elastase-induced emphysema in mice. Exp Lung Res 33(6):277-288. doi:10.1080/01902140701509458
-
(2007)
Exp Lung Res
, vol.33
, Issue.6
, pp. 277-288
-
-
Sawada, M.1
Ohno, Y.2
La, B.L.3
Funaguchi, N.4
Asai, T.5
Yuhgetsu, H.6
Takemura, G.7
Minatoguchi, S.8
Fujiwara, H.9
Fujiwara, T.10
-
24
-
-
84901209116
-
Proteoglycans maintain lung stability in an elastase-treated mouse model of emphysema
-
Takahashi A, Majumdar A, Parameswaran H, Bartolak-Suki E, Suki B (2014) Proteoglycans maintain lung stability in an elastase-treated mouse model of emphysema. Am J Respir Cell Mol Biol 51(1):26-33. doi:10.1165/rcmb.2013-0179OC
-
(2014)
Am J Respir Cell Mol Biol
, vol.51
, Issue.1
, pp. 26-33
-
-
Takahashi, A.1
Majumdar, A.2
Parameswaran, H.3
Bartolak-Suki, E.4
Suki, B.5
-
25
-
-
33644822447
-
Quantitative characterization of airspace enlargement in emphysema
-
Parameswaran H, Majumdar A, Ito S, Alencar AM, Suki B (2006) Quantitative characterization of airspace enlargement in emphysema. J Appl Physiol 100(1):186-193
-
(2006)
J Appl Physiol
, vol.100
, Issue.1
, pp. 186-193
-
-
Parameswaran, H.1
Majumdar, A.2
Ito, S.3
Alencar, A.M.4
Suki, B.5
-
26
-
-
0035891566
-
Roles of mechanical forces and collagen failure in the development of elastase-induced emphysema
-
Pt 1
-
Kononov S, Brewer K, Sakai H, Cavalcante FS, Sabayanagam CR, Ingenito EP, Suki B (2001) Roles of mechanical forces and collagen failure in the development of elastase-induced emphysema. Am J Respir Crit Care Med 164(10 Pt 1):1920-1926
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.10
, pp. 1920-1926
-
-
Kononov, S.1
Brewer, K.2
Sakai, H.3
Cavalcante, F.S.4
Sabayanagam, C.R.5
Ingenito, E.P.6
Suki, B.7
|