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Volumn 5, Issue APR, 2017, Pages

Salivary diagnostics in pediatrics: Applicability, translatability, and limitations

Author keywords

Diagnostics; Genetics; Newborns; Pediatrics; Saliva

Indexed keywords


EID: 85032373809     PISSN: None     EISSN: 22962565     Source Type: Journal    
DOI: 10.3389/FPUBH.2017.00083     Document Type: Short Survey
Times cited : (36)

References (113)
  • 1
    • 84971629596 scopus 로고    scopus 로고
    • Usefulness of new and traditional serum biomarkers in children with suspected appendicitis
    • Benito J, Acedo Y, Medrano L, Barcena E, Garay RP, Arri EA. Usefulness of new and traditional serum biomarkers in children with suspected appendicitis. Am J Emerg Med (2016) 34:871-6. doi:10.1016/j.ajem.2016.02.011
    • (2016) Am J Emerg Med , vol.34 , pp. 871-876
    • Benito, J.1    Acedo, Y.2    Medrano, L.3    Barcena, E.4    Garay, R.P.5    Arri, E.A.6
  • 2
    • 84961046795 scopus 로고    scopus 로고
    • Decreased serum miR-503 level in children with nephrotic syndrome
    • Wang H, Hu J, Chen L. Decreased serum miR-503 level in children with nephrotic syndrome. Clin Lab (2015) 61:1917-26. doi:10.7754/Clin.Lab.2015.150407
    • (2015) Clin Lab , vol.61 , pp. 1917-1926
    • Wang, H.1    Hu, J.2    Chen, L.3
  • 3
    • 0024394808 scopus 로고
    • Serum pepsinogen I and IgG antibody to Camplylobacter pylori in non-specific abdominal pain in childhood
    • Odera G, Vaira D, Holton J, Dowsett JF, Ansaldi N. Serum pepsinogen I and IgG antibody to Camplylobacter pylori in non-specific abdominal pain in childhood. Gut (1989) 30:912-6. doi:10.1136/gut.30.7.912
    • (1989) Gut , vol.30 , pp. 912-916
    • Odera, G.1    Vaira, D.2    Holton, J.3    Dowsett, J.F.4    Ansaldi, N.5
  • 4
    • 0025974916 scopus 로고
    • Analysis of pancreatic serum markers in patients with cystic fibrosis
    • Scheuring U, Skopnik H, Roth B, Uhlenbruck G, Metzgar RS. Analysis of pancreatic serum markers in patients with cystic fibrosis. Pancreas (1991) 6:229-33. doi:10.1097/00006676-199103000-00016
    • (1991) Pancreas , vol.6 , pp. 229-233
    • Scheuring, U.1    Skopnik, H.2    Roth, B.3    Uhlenbruck, G.4    Metzgar, R.S.5
  • 5
    • 84931573777 scopus 로고    scopus 로고
    • Markedly raised levels of C-reactive protein are associated with culture-proven sepsis or necrotizing enterocolitis in extremely preterm neonates
    • Keane M, Fallon R, Riordan A, Shaw B. Markedly raised levels of C-reactive protein are associated with culture-proven sepsis or necrotizing enterocolitis in extremely preterm neonates. Acta Paediatr (2015) 104:e289-93. doi:10.1111/apa.12978
    • (2015) Acta Paediatr , vol.104
    • Keane, M.1    Fallon, R.2    Riordan, A.3    Shaw, B.4
  • 6
    • 84944049784 scopus 로고    scopus 로고
    • Diagnostic utility of biomarkers for neonatal sepsis-a systematic review
    • Hedegaard SS, Wisborg K, Hvas AM. Diagnostic utility of biomarkers for neonatal sepsis-a systematic review. Infect Dis (2015) 47:117-24. doi:10.3109/00365548.2014.971053
    • (2015) Infect Dis , vol.47 , pp. 117-124
    • Hedegaard, S.S.1    Wisborg, K.2    Hvas, A.M.3
  • 8
    • 84867895007 scopus 로고    scopus 로고
    • Salivary biomarker development using genomic, proteomic and metabolomic approaches
    • Bonne NJ, Wong DT. Salivary biomarker development using genomic, proteomic and metabolomic approaches. Genome Med (2012) 4:82. doi:10.1186/gm383
    • (2012) Genome Med , vol.4 , pp. 82
    • Bonne, N.J.1    Wong, D.T.2
  • 10
    • 84969142807 scopus 로고    scopus 로고
    • Saliva as a diagnostic tool for oral and systemic diseases
    • Javaid MA, Ahmed AS, Durand R, Tran SD. Saliva as a diagnostic tool for oral and systemic diseases. J Oral Biol Craniofac Res (2016) 6:66-75. doi:10.1016/j.jobcr.2015.08.006
    • (2016) J Oral Biol Craniofac Res , vol.6 , pp. 66-75
    • Javaid, M.A.1    Ahmed, A.S.2    Durand, R.3    Tran, S.D.4
  • 11
    • 84930453353 scopus 로고    scopus 로고
    • Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid
    • Nunes LA, Mussavira S, Bindhu OS. Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid. Biochem Med (2015) 5:177-92. doi:10.11613/BM.2015.018
    • (2015) Biochem Med , vol.5 , pp. 177-192
    • Nunes, L.A.1    Mussavira, S.2    Bindhu, O.S.3
  • 12
    • 84921983343 scopus 로고    scopus 로고
    • Early repetitive pain in preterm infants in relation to the developing brain
    • Ranger M, Grunau RE. Early repetitive pain in preterm infants in relation to the developing brain. Pain Manag (2014) 4:57-67. doi:10.2217/pmt.13.61
    • (2014) Pain Manag , vol.4 , pp. 57-67
    • Ranger, M.1    Grunau, R.E.2
  • 13
    • 84898958371 scopus 로고    scopus 로고
    • Impact of repeated procedural pain-related stress in infants born very preterm
    • Vinall J, Grunau RE. Impact of repeated procedural pain-related stress in infants born very preterm. Pediatr Res (2014) 75:584-7. doi:10.1038/pr.2014.16
    • (2014) Pediatr Res , vol.75 , pp. 584-587
    • Vinall, J.1    Grunau, R.E.2
  • 14
    • 85032393800 scopus 로고    scopus 로고
    • Field MJ, Behrman RE, editors. Ethical Conduct of Clinical Research Involving Children. Washington, DC: National Academies Press 2004). 2, The Necessity and Challenges of Clinical Research Involving Children. Available from:
    • Institute of Medicine (US) Committee on Clinical Research Involving Children, Field MJ, Behrman RE, editors. Ethical Conduct of Clinical Research Involving Children. Washington, DC: National Academies Press (2004). 2, The Necessity and Challenges of Clinical Research Involving Children. Available from: http://www.ncbi.nlm.nih.gov/books/NBK25553/
  • 16
    • 85032330387 scopus 로고    scopus 로고
    • Available from:
    • U.S. Food and Drug Administration. Additional Protections for Children. (2001). Available from: http://www.fda.gov/ScienceResearch/SpecialTopics/RunningClinicalTrials/ucm119111.htm
    • (2001) Additional Protections for Children
  • 17
    • 80052815900 scopus 로고    scopus 로고
    • Scientific frontiers: emerging technologies for salivary diagnostics
    • Baum BJ, Yates JR III, Srivastava S, Wong DT, Melvin JE. Scientific frontiers: emerging technologies for salivary diagnostics. Adv Dent Res (2011) 23:360-8. doi:10.1177/0022034511420433
    • (2011) Adv Dent Res , vol.23 , pp. 360-368
    • Baum, B.J.1    Yates J.R, I.I.I.2    Srivastava, S.3    Wong, D.T.4    Melvin, J.E.5
  • 19
    • 84875894488 scopus 로고    scopus 로고
    • Salivomics
    • Wong DT. Salivomics. J Am Dent Assoc (2012) 143:19S-24S. doi:10.14219/jada.archive.2012.0339
    • (2012) J Am Dent Assoc , vol.143 , pp. 19S-24S
    • Wong, D.T.1
  • 20
    • 70449379016 scopus 로고    scopus 로고
    • Saliva: an emerging biofluid for early detection of diseases
    • Lee YH, Wong DT. Saliva: an emerging biofluid for early detection of diseases. Am J Dent (2009) 22:241-8.
    • (2009) Am J Dent , vol.22 , pp. 241-248
    • Lee, Y.H.1    Wong, D.T.2
  • 21
    • 46049108603 scopus 로고    scopus 로고
    • Salivary diagnostics: enhancing disease detection and making medicine better
    • Segal A, Wong DT. Salivary diagnostics: enhancing disease detection and making medicine better. Eur J Dent Educ (2008) 12(Suppl 1):22-9. doi:10.1111/j.1600-0579.2007.00477.x
    • (2008) Eur J Dent Educ , vol.12 , pp. 22-29
    • Segal, A.1    Wong, D.T.2
  • 22
    • 0035257183 scopus 로고    scopus 로고
    • A review of saliva: normal composition, flow, and function
    • Humphrey SP, Williamson RT. A review of saliva: normal composition, flow, and function. J Prosthet Dent (2001) 85:162-9. doi:10.1067/mpr.2001.113778
    • (2001) J Prosthet Dent , vol.85 , pp. 162-169
    • Humphrey, S.P.1    Williamson, R.T.2
  • 23
    • 84874820619 scopus 로고    scopus 로고
    • The secretion, components, and properties of saliva
    • Carpenter GH. The secretion, components, and properties of saliva. Annu Rev Food Sci Technol (2013) 4:267-76. doi:10.1146/annurev-food-030212-182700
    • (2013) Annu Rev Food Sci Technol , vol.4 , pp. 267-276
    • Carpenter, G.H.1
  • 24
    • 0026668614 scopus 로고
    • Therapeutic drug monitoring in saliva: an update
    • Drobitch RK, Svensson CK. Therapeutic drug monitoring in saliva: an update. Clin Pharmacokinet (1992) 23:365-79. doi:10.2165/00003088-199223050-00003
    • (1992) Clin Pharmacokinet , vol.23 , pp. 365-379
    • Drobitch, R.K.1    Svensson, C.K.2
  • 25
    • 0025582674 scopus 로고
    • Composition of whole unstimulated saliva of healthy children: changes with age
    • Ben-Aryeh H, Fisher M, Szargel R, Laufer D. Composition of whole unstimulated saliva of healthy children: changes with age. Arch Oral Biol (1990) 35:929-31. doi:10.1016/0003-9969(90)90075-L
    • (1990) Arch Oral Biol , vol.35 , pp. 929-931
    • Ben-Aryeh, H.1    Fisher, M.2    Szargel, R.3    Laufer, D.4
  • 27
    • 0002719293 scopus 로고
    • Development of the salivary glands
    • In: Sreebny LM, editor. The Salivary System. Boca Raton, FL: CRC Press
    • Redman RS. Development of the salivary glands. In: Sreebny LM, editor. The Salivary System. Boca Raton, FL: CRC Press (1987). p. 2-17.
    • (1987) , pp. 2-17
    • Redman, R.S.1
  • 28
    • 0021273867 scopus 로고
    • Development of salivary a-amylase in infants from birth to 5 months
    • Sevenhuysen GP, Holodinsky C, Dawes C. Development of salivary a-amylase in infants from birth to 5 months. Am J Clin Nutr (1984) 39:584-8.
    • (1984) Am J Clin Nutr , vol.39 , pp. 584-588
    • Sevenhuysen, G.P.1    Holodinsky, C.2    Dawes, C.3
  • 30
    • 84949558797 scopus 로고    scopus 로고
    • Age differences of salivary alpha-amylase levels of basal and acute responses to citric acid stimulation between Chinese children and adults
    • Yang Z-M, Chen L-H, Zhang M, Lin J, Zhang J, Chen WW, et al. Age differences of salivary alpha-amylase levels of basal and acute responses to citric acid stimulation between Chinese children and adults. Front Physiol (2015) 6:340. doi:10.3389/fphys.2015.00340
    • (2015) Front Physiol , vol.6 , pp. 340
    • Yang, Z-M.1    Chen, L-H.2    Zhang, M.3    Lin, J.4    Zhang, J.5    Chen, W.W.6
  • 31
    • 84928604665 scopus 로고    scopus 로고
    • Attenuated acute salivary a-amylase responses to gustatory stimulation with citric acid in thin children
    • Chen LH, Yang ZM, Chen WW, Lin J, Zhang M, Yang XR, et al. Attenuated acute salivary a-amylase responses to gustatory stimulation with citric acid in thin children. Br J Nutr (2015) 113:1078-85. doi:10.1017/S0007114515000446
    • (2015) Br J Nutr , vol.113 , pp. 1078-1085
    • Chen, L.H.1    Yang, Z.M.2    Chen, W.W.3    Lin, J.4    Zhang, M.5    Yang, X.R.6
  • 33
    • 84983056926 scopus 로고    scopus 로고
    • Microbial changes during pregnancy, birth, and infancy
    • Nuriel-Ohayon M, Neuman H, Koren O. Microbial changes during pregnancy, birth, and infancy. Front Microbiol (2016) 7:1031. doi:10.3389/fmicb.2016.01031
    • (2016) Front Microbiol , vol.7 , pp. 1031
    • Nuriel-Ohayon, M.1    Neuman, H.2    Koren, O.3
  • 34
    • 84930599349 scopus 로고    scopus 로고
    • Early microbial contact, the breast milk microbiome and child health
    • Rautava S. Early microbial contact, the breast milk microbiome and child health. J Dev Orig Health Dis (2016) 7:5-14. doi:10.1017/S2040174415001233
    • (2016) J Dev Orig Health Dis , vol.7 , pp. 5-14
    • Rautava, S.1
  • 35
    • 85050920580 scopus 로고    scopus 로고
    • External influence of early childhood establishment of gut microbiota and subsequent health implications
    • Munyaka PM, Khafipour E, Ghia JE. External influence of early childhood establishment of gut microbiota and subsequent health implications. Front Pediatr (2014) 2:109. doi:10.3389/fped.2014.00109
    • (2014) Front Pediatr , vol.2 , pp. 109
    • Munyaka, P.M.1    Khafipour, E.2    Ghia, J.E.3
  • 36
    • 77955386857 scopus 로고    scopus 로고
    • Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
    • Dominguez-Bello MG, Costello EK, Contreras M, Magris M, Hidalgo G, Fierer N, et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci U S A (2010) 107:11971-5. doi:10.1073/pnas.1002601107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11971-11975
    • Dominguez-Bello, M.G.1    Costello, E.K.2    Contreras, M.3    Magris, M.4    Hidalgo, G.5    Fierer, N.6
  • 37
    • 0032974177 scopus 로고    scopus 로고
    • Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery
    • Gronlund MM, Lehtonen OP, Eerola E, Kero P. Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Pediatr Gastroenterol Nutr (1999) 28:19-25. doi:10.1097/00005176-199901000-00007
    • (1999) J Pediatr Gastroenterol Nutr , vol.28 , pp. 19-25
    • Gronlund, M.M.1    Lehtonen, O.P.2    Eerola, E.3    Kero, P.4
  • 38
    • 52649117166 scopus 로고    scopus 로고
    • Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation
    • DiGiulio DB, Romero R, Amogan HP, Kusanovic JP, Bik EM, Gotsch F, et al. Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation. PLoS One (2008) 3:e3056. doi:10.1371/journal.pone.0003056
    • (2008) PLoS One , vol.3
    • DiGiulio, D.B.1    Romero, R.2    Amogan, H.P.3    Kusanovic, J.P.4    Bik, E.M.5    Gotsch, F.6
  • 39
    • 84862206263 scopus 로고    scopus 로고
    • Human infant saliva peptidome is modified with age and diet transition
    • Morzel M, Jeannin A, Lucchi G, Truntzer C, Pecqueur D, Nicklaus S, et al. Human infant saliva peptidome is modified with age and diet transition. J Proteomics (2012) 75:3665-73. doi:10.1016/j.jprot.2012.04.028
    • (2012) J Proteomics , vol.75 , pp. 3665-3673
    • Morzel, M.1    Jeannin, A.2    Lucchi, G.3    Truntzer, C.4    Pecqueur, D.5    Nicklaus, S.6
  • 40
    • 79959378471 scopus 로고    scopus 로고
    • Saliva electrophoretic protein profiles in infants: changes with age and impact of teeth eruption and diet transition
    • Morzel M, Palicki O, Chabanet C, Lucchi G, Ducoroy P, Chambon C, et al. Saliva electrophoretic protein profiles in infants: changes with age and impact of teeth eruption and diet transition. Arch Oral Biol (2011) 56:634-42. doi:10.1016/j.archoralbio.2010.12.015
    • (2011) Arch Oral Biol , vol.56 , pp. 634-642
    • Morzel, M.1    Palicki, O.2    Chabanet, C.3    Lucchi, G.4    Ducoroy, P.5    Chambon, C.6
  • 41
    • 0031085089 scopus 로고    scopus 로고
    • Evaluation of components of gingival crevicular fluid as diagnostic tests
    • Lamster IB. Evaluation of components of gingival crevicular fluid as diagnostic tests. Ann Periodontol (1997) 2:123-37. doi:10.1902/annals.1997.2.1.123
    • (1997) Ann Periodontol , vol.2 , pp. 123-137
    • Lamster, I.B.1
  • 42
    • 85001975618 scopus 로고    scopus 로고
    • Human leukocyte antigen typing using buccal swabs as accurate and non-invasive substitute for venipuncture in children at risk for celiac disease
    • Adriaanse MP, Vreugdenhil AC, Vastmans V, Groeneveld L, Molenbroeck S, Schott DA. Human leukocyte antigen typing using buccal swabs as accurate and non-invasive substitute for venipuncture in children at risk for celiac disease. J Gastroenterol Hepatol (2016) 31:1711-16. doi:10.1111/jgh.13331
    • (2016) J Gastroenterol Hepatol , vol.31 , pp. 1711-1716
    • Adriaanse, M.P.1    Vreugdenhil, A.C.2    Vastmans, V.3    Groeneveld, L.4    Molenbroeck, S.5    Schott, D.A.6
  • 43
    • 0036048227 scopus 로고    scopus 로고
    • DNA extraction and HLA genotyping using mailed mouth brushes from children
    • Witsø E, Stene LC, Paltiel L, Joner G, Rønningen KS. DNA extraction and HLA genotyping using mailed mouth brushes from children. Pediatr Diabetes (2002) 3:89-94. doi:10.1034/j.1399-5448.2002.30205.x
    • (2002) Pediatr Diabetes , vol.3 , pp. 89-94
    • Witsø, E.1    Stene, L.C.2    Paltiel, L.3    Joner, G.4    Rønningen, K.S.5
  • 45
    • 84989842529 scopus 로고    scopus 로고
    • Evaluation and comparison of in vitro degradation kinetics of DNA in serum, urine and saliva: a qualitative study
    • Yao W, Mei C, Nan X, Hui L. Evaluation and comparison of in vitro degradation kinetics of DNA in serum, urine and saliva: a qualitative study. Gene (2016) 15:142-8. doi:10.1016/j.gene.2016.06.033
    • (2016) Gene , vol.15 , pp. 142-148
    • Yao, W.1    Mei, C.2    Nan, X.3    Hui, L.4
  • 46
    • 84923547728 scopus 로고    scopus 로고
    • Detection of exosomal biomarker by electric field-induced release and measurement (ERIFM)
    • Tu M, Wei F, Yang J, Wong D. Detection of exosomal biomarker by electric field-induced release and measurement (ERIFM). J Vis Exp (2015) 95:52439. doi:10.3791/52439
    • (2015) J Vis Exp , vol.95 , pp. 52439
    • Tu, M.1    Wei, F.2    Yang, J.3    Wong, D.4
  • 47
    • 85010438524 scopus 로고    scopus 로고
    • Genomic analysis of plasma cell-free DNA in patients with cancer
    • Oxnard GR, Paweletz CP, Sholl LM. Genomic analysis of plasma cell-free DNA in patients with cancer. JAMA Oncol (2016). doi:10.1001/jamaoncol.2016.2835
    • (2016) JAMA Oncol
    • Oxnard, G.R.1    Paweletz, C.P.2    Sholl, L.M.3
  • 48
    • 84990236512 scopus 로고    scopus 로고
    • Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: a pilot study
    • Pu D, Liang H, Wei F, Akin D, Feng Z, Yan Q, et al. Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: a pilot study. Thorac Cancer (2016) 7:428-38. doi:10.1111/1759-7714.12350
    • (2016) Thorac Cancer , vol.7 , pp. 428-438
    • Pu, D.1    Liang, H.2    Wei, F.3    Akin, D.4    Feng, Z.5    Yan, Q.6
  • 49
    • 77649222222 scopus 로고    scopus 로고
    • Neonatal salivary analysis reveals global developmental gene expression changes in the premature infant
    • Maron JL, Johnson KL, Rocke DM, Cohen MG, Liley AJ, Bianchi DW. Neonatal salivary analysis reveals global developmental gene expression changes in the premature infant. Clin Chem (2010) 56:409-16. doi:10.1373/clinchem.2009.136234
    • (2010) Clin Chem , vol.56 , pp. 409-416
    • Maron, J.L.1    Johnson, K.L.2    Rocke, D.M.3    Cohen, M.G.4    Liley, A.J.5    Bianchi, D.W.6
  • 50
    • 84959515374 scopus 로고    scopus 로고
    • The neonatal transcriptome
    • Maron JL. The neonatal transcriptome. Cold Spring Harb Perspect Med (2015) 6:a026369. doi:10.1101/cshperspect.a026369
    • (2015) Cold Spring Harb Perspect Med , vol.6
    • Maron, J.L.1
  • 51
    • 79955131733 scopus 로고    scopus 로고
    • Exploring the neonatal salivary transcriptome: technical optimization and clinical applications
    • Maron JL. Exploring the neonatal salivary transcriptome: technical optimization and clinical applications. Clin Biochem (2011) 44:467-8. doi:10.1016/j.clinbiochem.2011.03.019
    • (2011) Clin Biochem , vol.44 , pp. 467-468
    • Maron, J.L.1
  • 52
    • 84921497587 scopus 로고    scopus 로고
    • Computational gene expression modeling identifies salivary biomarker analysis that predict oral feeding readiness in the newborn
    • Maron JL, Hwang JS, Pathak S, Ruthazer R, Russell RL, Alterovtiz G. Computational gene expression modeling identifies salivary biomarker analysis that predict oral feeding readiness in the newborn. J Pediatr (2014) 166:282-8. doi:10.1016/j.jpeds.2014.10.065
    • (2014) J Pediatr , vol.166 , pp. 282-288
    • Maron, J.L.1    Hwang, J.S.2    Pathak, S.3    Ruthazer, R.4    Russell, R.L.5    Alterovtiz, G.6
  • 53
    • 84861309381 scopus 로고    scopus 로고
    • Neuropepetide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate
    • Maron JL, Johnson KL, Dietz JA, Chen ML, Bianchi DW. Neuropepetide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate. PLoS One (2012) 7:e37870. doi:10.1371/journal.pone.0037870
    • (2012) PLoS One , vol.7
    • Maron, J.L.1    Johnson, K.L.2    Dietz, J.A.3    Chen, M.L.4    Bianchi, D.W.5
  • 54
    • 85032360804 scopus 로고    scopus 로고
    • Salivary FOXP2 expression and oral feeding success in premature infants
    • Zimmerman E, Maki M, Maron J. Salivary FOXP2 expression and oral feeding success in premature infants. Cold Spring Harb Mol Case Stud (2016) 2:a000554. doi:10.1101/mcs.a000554
    • (2016) Cold Spring Harb Mol Case Stud , vol.2
    • Zimmerman, E.1    Maki, M.2    Maron, J.3
  • 55
    • 85032341510 scopus 로고    scopus 로고
    • FOXP2 gene deletion and infant feeding difficulties: a case report
    • Zimmerman E, Maron JL. FOXP2 gene deletion and infant feeding difficulties: a case report. Cold Spring Harb Mol Case Stud (2016) 2:a000547. doi:10.1101/mcsa000547
    • (2016) Cold Spring Harb Mol Case Stud , vol.2
    • Zimmerman, E.1    Maron, J.L.2
  • 57
    • 84865963195 scopus 로고    scopus 로고
    • Point-of-care platforms for salivary diagnostics
    • Wei F, Wong DT. Point-of-care platforms for salivary diagnostics. Chin J Dent Res (2012) 15:7-15.
    • (2012) Chin J Dent Res , vol.15 , pp. 7-15
    • Wei, F.1    Wong, D.T.2
  • 58
    • 79953737346 scopus 로고    scopus 로고
    • Saliva: diagnostics and therapeutic perspectives
    • Spielmann N, Wong DT. Saliva: diagnostics and therapeutic perspectives. Oral Dis (2011) 17:345-54. doi:10.1111/j.1601-0825.2010.01773.x
    • (2011) Oral Dis , vol.17 , pp. 345-354
    • Spielmann, N.1    Wong, D.T.2
  • 59
    • 33645035375 scopus 로고    scopus 로고
    • Salivary diagnostics powered by nanotechnologies, proteomics and genomics
    • Wong DT. Salivary diagnostics powered by nanotechnologies, proteomics and genomics. J Am Dent Assoc (2006) 137:313-21. doi:10.14219/jada.archive.2006.0180
    • (2006) J Am Dent Assoc , vol.137 , pp. 313-321
    • Wong, D.T.1
  • 60
    • 84891706880 scopus 로고    scopus 로고
    • The proteomic revolution in laboratory medicine
    • Pasic MD, Yousef GM, Diamandis EP. The proteomic revolution in laboratory medicine. Clin Biochem (2013) 6:397-8. doi:10.1016/j.clinbiochem.2013.02.012
    • (2013) Clin Biochem , vol.6 , pp. 397-398
    • Pasic, M.D.1    Yousef, G.M.2    Diamandis, E.P.3
  • 62
    • 84881142917 scopus 로고    scopus 로고
    • Saliva proteome research: current status and future outlook
    • Schulz BL, Cooper-White J, Punyadeera CK. Saliva proteome research: current status and future outlook. Crit Rev Biotechnol (2013) 33:246-59. doi:10.3109/07388551.2012.687361
    • (2013) Crit Rev Biotechnol , vol.33 , pp. 246-259
    • Schulz, B.L.1    Cooper-White, J.2    Punyadeera, C.K.3
  • 63
    • 34548324635 scopus 로고    scopus 로고
    • Human saliva proteome analysis and disease biomarker discovery
    • Hu S, Loo JA, Wong DT. Human saliva proteome analysis and disease biomarker discovery. Expert Rev Proteomics (2007) 4:531-8. doi:10.1586/14789450.4.4.531
    • (2007) Expert Rev Proteomics , vol.4 , pp. 531-538
    • Hu, S.1    Loo, J.A.2    Wong, D.T.3
  • 64
    • 3843142873 scopus 로고    scopus 로고
    • Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma
    • John MA, Li Y, Zhou X, Denny P, Ho CM, Montemagno C, et al. Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2004) 130:929-35. doi:10.1001/archotol.130.8.929
    • (2004) Arch Otolaryngol Head Neck Surg , vol.130 , pp. 929-935
    • John, M.A.1    Li, Y.2    Zhou, X.3    Denny, P.4    Ho, C.M.5    Montemagno, C.6
  • 65
    • 84959343666 scopus 로고    scopus 로고
    • Recent advances in salivary cancer diagnostics enabled by biosensors and bioelectronics
    • Mishra S, Saadat D, Kwon O, Lee Y, Choi WS, Kim JH, et al. Recent advances in salivary cancer diagnostics enabled by biosensors and bioelectronics. Biosens Bioelectron (2016) 81:181-97. doi:10.1016/j.bios.2016.02.040
    • (2016) Biosens Bioelectron , vol.81 , pp. 181-197
    • Mishra, S.1    Saadat, D.2    Kwon, O.3    Lee, Y.4    Choi, W.S.5    Kim, J.H.6
  • 66
    • 35548992599 scopus 로고    scopus 로고
    • Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome
    • Hu S, Wang J, Meijer J, Ieong S, Xie Y, Yu T, et al. Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome. Arthritis Rheum (2007) 56:3588-600. doi:10.1002/art.22954
    • (2007) Arthritis Rheum , vol.56 , pp. 3588-3600
    • Hu, S.1    Wang, J.2    Meijer, J.3    Ieong, S.4    Xie, Y.5    Yu, T.6
  • 67
    • 84926452154 scopus 로고    scopus 로고
    • Can saliva proteins be used to predict the onset of acute myocardial infarction among high-risk patients
    • Rahim MA, Rahim ZH, Ahmad WA, Hashim OH. Can saliva proteins be used to predict the onset of acute myocardial infarction among high-risk patients. Int J Med Sci (2015) 12:329-35. doi:10.7150/ijms.11280
    • (2015) Int J Med Sci , vol.12 , pp. 329-335
    • Rahim, M.A.1    Rahim, Z.H.2    Ahmad, W.A.3    Hashim, O.H.4
  • 68
    • 77953254220 scopus 로고    scopus 로고
    • Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease
    • Nicholas BL, Skipp P, Barton S, Singh D, Bagmane D, Mould R, et al. Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 181:1049-60. doi:10.1164/rccm.200906-0857OC
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 1049-1060
    • Nicholas, B.L.1    Skipp, P.2    Barton, S.3    Singh, D.4    Bagmane, D.5    Mould, R.6
  • 69
    • 33846990928 scopus 로고    scopus 로고
    • Salivary protein profiling in type I diabetes using two-dimensional electrophoresis and mass spectrometry
    • Hirtz C, Chevalier F, Sommerer N, Raingeard I, Bringer J, Rossignol M, et al. Salivary protein profiling in type I diabetes using two-dimensional electrophoresis and mass spectrometry. Clin Proteomics (2006) 2:117-27. doi:10.1385/CP:2:1:117
    • (2006) Clin Proteomics , vol.2 , pp. 117-127
    • Hirtz, C.1    Chevalier, F.2    Sommerer, N.3    Raingeard, I.4    Bringer, J.5    Rossignol, M.6
  • 70
    • 68549101972 scopus 로고    scopus 로고
    • Age-dependent modifications of the human salivary secretory protein complex
    • Cabras T, Pisano E, Boi R, Olianas A, Manconi B, Inzitari R, et al. Age-dependent modifications of the human salivary secretory protein complex. J Proteome Res (2009) 8:4126-34. doi:10.1021/pr900212u
    • (2009) J Proteome Res , vol.8 , pp. 4126-4134
    • Cabras, T.1    Pisano, E.2    Boi, R.3    Olianas, A.4    Manconi, B.5    Inzitari, R.6
  • 71
    • 84908226539 scopus 로고    scopus 로고
    • The relationship between salivary insulin-like growth factor I and quantitative cervical maturational stages of skeletal maturity
    • Nayak S, Bhad WA, Doshi UH. The relationship between salivary insulin-like growth factor I and quantitative cervical maturational stages of skeletal maturity. J Orthod (2014) 41:170-4. doi:10.1179/1465313313Y.0000000091
    • (2014) J Orthod , vol.41 , pp. 170-174
    • Nayak, S.1    Bhad, W.A.2    Doshi, U.H.3
  • 72
    • 84926431778 scopus 로고    scopus 로고
    • Chrono-proteomics of human saliva: variations of the salivary proteome during human development
    • Messana I, Cabras T, Iavarone F, Manconi B, Huang L, Martelli C, et al. Chrono-proteomics of human saliva: variations of the salivary proteome during human development. J Proteome Res (2015) 14:1666-77. doi:10.1021/pr501270x
    • (2015) J Proteome Res , vol.14 , pp. 1666-1677
    • Messana, I.1    Cabras, T.2    Iavarone, F.3    Manconi, B.4    Huang, L.5    Martelli, C.6
  • 74
    • 84947967411 scopus 로고    scopus 로고
    • Continuous metabolic syndrome scores for children using salivary biomarkers
    • Shi P, Goodson JM, Hartman ML, Hasturk H, Yaskell T, Vargas J, et al. Continuous metabolic syndrome scores for children using salivary biomarkers. PLoS One (2015) 10:e0138979. doi:10.1371/journal.pone.0138979
    • (2015) PLoS One , vol.10
    • Shi, P.1    Goodson, J.M.2    Hartman, M.L.3    Hasturk, H.4    Yaskell, T.5    Vargas, J.6
  • 75
    • 84872301697 scopus 로고    scopus 로고
    • Glucose estimation in the salivary secretion of diabetes mellitus patients
    • Abikshyeet P, Ramesh V, Oza N. Glucose estimation in the salivary secretion of diabetes mellitus patients. Diabetes Metab Syndr Obes (2012) 5:149-54. doi:10.2147/DMSO.S32112
    • (2012) Diabetes Metab Syndr Obes , vol.5 , pp. 149-154
    • Abikshyeet, P.1    Ramesh, V.2    Oza, N.3
  • 77
    • 0026857445 scopus 로고
    • Two-year longitudinal observations of salivary status and dental caries in children with insulin-dependent diabetes mellitus
    • Twetman S, Nederfors T, Stahl B, Aronson S. Two-year longitudinal observations of salivary status and dental caries in children with insulin-dependent diabetes mellitus. Pediatr Dent (1992) 14:184-8.
    • (1992) Pediatr Dent , vol.14 , pp. 184-188
    • Twetman, S.1    Nederfors, T.2    Stahl, B.3    Aronson, S.4
  • 78
    • 84956592215 scopus 로고    scopus 로고
    • Glucose level estimation in diabetes mellitus by saliva: a bloodless revolution
    • Kadashetti V, Baad R, Malik N, Shivakumar KM, Vibhute N, Belgaumi U, et al. Glucose level estimation in diabetes mellitus by saliva: a bloodless revolution. Rom J Intern Med (2015) 53:248-52. doi:10.1515/rjim-2015-0032
    • (2015) Rom J Intern Med , vol.53 , pp. 248-252
    • Kadashetti, V.1    Baad, R.2    Malik, N.3    Shivakumar, K.M.4    Vibhute, N.5    Belgaumi, U.6
  • 79
    • 84959011025 scopus 로고    scopus 로고
    • Salivary proteomics: a new adjuvant approach to the early diagnosis of familial juvenile systemic lupus erythematosus
    • Abrão AL, Falcao DP, de Amorim RF, Bezerra AC, Pombeiro GA, Guimarães LJ, et al. Salivary proteomics: a new adjuvant approach to the early diagnosis of familial juvenile systemic lupus erythematosus. Med Hypotheses (2016) 89:97-100. doi:10.1016/j.mehy.2016.02.010
    • (2016) Med Hypotheses , vol.89 , pp. 97-100
    • Abrão, A.L.1    Falcao, D.P.2    de Amorim, R.F.3    Bezerra, A.C.4    Pombeiro, G.A.5    Guimarães, L.J.6
  • 80
    • 61349129152 scopus 로고    scopus 로고
    • Hypo-phosphorylation of salivary peptidome as a clue to the molecular pathogenesis of autism spectrum disorders
    • Castagnola M, Messana I, Inzitari R, Fanali C, Cabras T, Morelli A, et al. Hypo-phosphorylation of salivary peptidome as a clue to the molecular pathogenesis of autism spectrum disorders. J Proteome Res (2008) 7:5327-32. doi:10.1021/pr8004088
    • (2008) J Proteome Res , vol.7 , pp. 5327-5332
    • Castagnola, M.1    Messana, I.2    Inzitari, R.3    Fanali, C.4    Cabras, T.5    Morelli, A.6
  • 83
    • 85032343126 scopus 로고    scopus 로고
    • Available from:
    • WHO Fact Sheet. Children: Reducing Mortality (2016). Available from: https://www.who.int/mediacentre/factsheets/fs178/en/
    • (2016)
  • 85
    • 84934988710 scopus 로고    scopus 로고
    • Maturation of oral microbiota in children with or without dental caries
    • Lif Holgerson P, öhman C, Rönnlund A, Johansson I. Maturation of oral microbiota in children with or without dental caries. PLoS One (2015) 10:e0128534. doi:10.1371/journal.pone.0128534
    • (2015) PLoS One , vol.10
    • Lif Holgerson, P.1    Öhman, C.2    Rönnlund, A.3    Johansson, I.4
  • 86
    • 41549168638 scopus 로고    scopus 로고
    • Salivary genomics, transcriptomics, and proteomics: the emerging concept of the oral ecosystem and their use in the early diagnosis of cancer and other diseases
    • Fabian TK, Fejerdy P, Csermely P. Salivary genomics, transcriptomics, and proteomics: the emerging concept of the oral ecosystem and their use in the early diagnosis of cancer and other diseases. Curr Genomics (2008) 9:11-21. doi:10.2174/138920208783884900
    • (2008) Curr Genomics , vol.9 , pp. 11-21
    • Fabian, T.K.1    Fejerdy, P.2    Csermely, P.3
  • 87
    • 84949654900 scopus 로고    scopus 로고
    • Evaluation of saliva as diagnostic materials for influenza virus infection by PCR-based assays
    • Sueki A, Matsuda K, Yamaguchi A, Uehara M, Sugano M, Uehara T, et al. Evaluation of saliva as diagnostic materials for influenza virus infection by PCR-based assays. Clin Chim Acta (2015) 453:71-4. doi:10.1016/j.cca.2015.12.006
    • (2015) Clin Chim Acta , vol.453 , pp. 71-74
    • Sueki, A.1    Matsuda, K.2    Yamaguchi, A.3    Uehara, M.4    Sugano, M.5    Uehara, T.6
  • 89
    • 84858709750 scopus 로고    scopus 로고
    • Salivary shedding of Epstein-Barr virus and cytomegalovirus in people infected or not by human immunodeficiency virus 1
    • de França TR, Carvalho AD, Gomes VB, Gueiros LA, Porter SR, Leao JC. Salivary shedding of Epstein-Barr virus and cytomegalovirus in people infected or not by human immunodeficiency virus 1. Clin Oral Investig (2012) 16:659-64. doi:10.1007/s00784-011-0548-5
    • (2012) Clin Oral Investig , vol.16 , pp. 659-664
    • de França, T.R.1    Carvalho, A.D.2    Gomes, V.B.3    Gueiros, L.A.4    Porter, S.R.5    Leao, J.C.6
  • 90
    • 84965191824 scopus 로고    scopus 로고
    • Repeated measures study of weekly and daily cytomegalovirus shedding patterns in saliva and urine of healthy cytomegalovirus-seropositive children
    • Cannon MJ, Stowell JD, Clark R, Dollard PR, Johnson D, Mask K, et al. Repeated measures study of weekly and daily cytomegalovirus shedding patterns in saliva and urine of healthy cytomegalovirus-seropositive children. BMC Infect Dis (2014) 14:569. doi:10.1186/s12879-014-0569-1
    • (2014) BMC Infect Dis , vol.14 , pp. 569
    • Cannon, M.J.1    Stowell, J.D.2    Clark, R.3    Dollard, P.R.4    Johnson, D.5    Mask, K.6
  • 91
    • 84891944060 scopus 로고    scopus 로고
    • Analysis of the shedding of three ß-herpesviruses in urine and saliva of children with renal disease
    • Yamamoto Y, Morooka M, Hashimoto S, Ihra M, Yoshikawa T. Analysis of the shedding of three ß-herpesviruses in urine and saliva of children with renal disease. J Med Virol (2014) 86:505-11. doi:10.1002/jmv.23782
    • (2014) J Med Virol , vol.86 , pp. 505-511
    • Yamamoto, Y.1    Morooka, M.2    Hashimoto, S.3    Ihra, M.4    Yoshikawa, T.5
  • 92
    • 79956124352 scopus 로고    scopus 로고
    • Deafness and hereditary hearing loss overview
    • In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, et al., editors. GeneReviews®.Seattle, WA: University of Washington (1999). Available from:
    • Smith RJH, Shearer AE, Hildebrand MS, Camp GV. Deafness and hereditary hearing loss overview. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, et al., editors. GeneReviews®.Seattle, WA: University of Washington (1999). Available from: http://www.ncbi.nlm.nih.gov/books/NBK1434/
    • Smith, R.J.H.1    Shearer, A.E.2    Hildebrand, M.S.3    Camp, G.V.4
  • 93
    • 0013850901 scopus 로고
    • Cytomegalovirus infection in the newborn and in early childhood
    • Stern H, Tucker SM. Cytomegalovirus infection in the newborn and in early childhood. Lancet (1965) 2:1268-71. doi:10.1016/S0140-6736(65)92283-X
    • (1965) Lancet , vol.2 , pp. 1268-1271
    • Stern, H.1    Tucker, S.M.2
  • 94
    • 84922051541 scopus 로고    scopus 로고
    • Detection of congenital cytomegalovirus infection by real-time polymerase chain reaction analysis of saliva or urine specimens
    • Ross SA, Ahmed A, Palmer AL, Michaels MG, Sánchez PJ, Bernstein DI, et al. Detection of congenital cytomegalovirus infection by real-time polymerase chain reaction analysis of saliva or urine specimens. J Infect Dis (2014) 210:1415-8. doi:10.1093/infdis/jiu263
    • (2014) J Infect Dis , vol.210 , pp. 1415-1418
    • Ross, S.A.1    Ahmed, A.2    Palmer, A.L.3    Michaels, M.G.4    Sánchez, P.J.5    Bernstein, D.I.6
  • 95
    • 84960797562 scopus 로고    scopus 로고
    • Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016
    • Barzon L, Pacenti M, Berto A, Sinigaglia A, Franchin E, Lavezzo E, et al. Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016. Euro Surveill (2016) 21(10):30159. doi:10.2807/1560-7917.ES.2016.21.10.30159
    • (2016) Euro Surveill , vol.21 , Issue.10 , pp. 30159
    • Barzon, L.1    Pacenti, M.2    Berto, A.3    Sinigaglia, A.4    Franchin, E.5    Lavezzo, E.6
  • 97
    • 0000725701 scopus 로고    scopus 로고
    • Synthesis and secretion of human salivary immunoglobulins
    • In: Garrett JR, Ekström J, Anderson LC, editors. Glandular Mechanisms of Salivary Secretion: Frontiers of Oral Biology, Basel: Karger
    • Brandrzaeg P. Synthesis and secretion of human salivary immunoglobulins. In: Garrett JR, Ekström J, Anderson LC, editors. Glandular Mechanisms of Salivary Secretion: Frontiers of Oral Biology. (Vol. 10), Basel: Karger (1998). p. 167-99.
    • (1998) , vol.10 , pp. 167-199
    • Brandrzaeg, P.1
  • 98
    • 0023763112 scopus 로고
    • Serum and salivary antibodies as indicators of rotavirus infection in neonates
    • Jayashree S, Bhan MK, Kumar R, Raj P, Glass R, Bhandari N. Serum and salivary antibodies as indicators of rotavirus infection in neonates. J Infect Dis (1988) 158:1117-20. doi:10.1093/infdis/158.5.1117
    • (1988) J Infect Dis , vol.158 , pp. 1117-1120
    • Jayashree, S.1    Bhan, M.K.2    Kumar, R.3    Raj, P.4    Glass, R.5    Bhandari, N.6
  • 99
    • 0027159981 scopus 로고
    • Serum and salivary responses to oral tetravalent reassortant rotavirus vaccine in newborns
    • Friedman MG, Segal B, Zedaka R, Sarov B, Margalith M, Bishop R, et al. Serum and salivary responses to oral tetravalent reassortant rotavirus vaccine in newborns. Clin Exp Immunol (1993) 92:194-9. doi:10.1111/j.1365-2249.1993.tb03379.x
    • (1993) Clin Exp Immunol , vol.92 , pp. 194-199
    • Friedman, M.G.1    Segal, B.2    Zedaka, R.3    Sarov, B.4    Margalith, M.5    Bishop, R.6
  • 100
    • 0030027391 scopus 로고    scopus 로고
    • Congenital rubella in south India: diagnosis using saliva from infants with cataract
    • Eckstein MB, Brown DW, Foster A, Richards AF, Gilbert CE, Vijayalakshmi P. Congenital rubella in south India: diagnosis using saliva from infants with cataract. BMJ (1996) 312:161. doi:10.1136/bmj.312.7024.161
    • (1996) BMJ , vol.312 , pp. 161
    • Eckstein, M.B.1    Brown, D.W.2    Foster, A.3    Richards, A.F.4    Gilbert, C.E.5    Vijayalakshmi, P.6
  • 101
    • 0035087160 scopus 로고    scopus 로고
    • Epidemiology of herpes simplex virus in children by detection of specific antibodies in saliva
    • Spicher VM, Bouvier P, Schlegel-Haueter SE, Morabia A, Siegrist CA. Epidemiology of herpes simplex virus in children by detection of specific antibodies in saliva. Pediatr Infect Dis J (2001) 20:265-72. doi:10.1097/00006454-200103000-00010
    • (2001) Pediatr Infect Dis J , vol.20 , pp. 265-272
    • Spicher, V.M.1    Bouvier, P.2    Schlegel-Haueter, S.E.3    Morabia, A.4    Siegrist, C.A.5
  • 102
    • 44149109633 scopus 로고    scopus 로고
    • Detection of measles-and mumps-specific IgG antibodies in paired serum and oral fluid samples from Norwegian conscripts
    • Vainio K, Samdal HH, Ånestad G, Wedege E, Skutlaberg DH, Bransdal KT, et al. Detection of measles-and mumps-specific IgG antibodies in paired serum and oral fluid samples from Norwegian conscripts. Eur J Clin Microbiol Infect Dis (2008) 27:461-5. doi:10.1007/s10096-008-0460-3
    • (2008) Eur J Clin Microbiol Infect Dis , vol.27 , pp. 461-465
    • Vainio, K.1    Samdal, H.H.2    Ånestad, G.3    Wedege, E.4    Skutlaberg, D.H.5    Bransdal, K.T.6
  • 104
    • 0025374291 scopus 로고
    • Detection of salivary immunoglobulin A antibodies to HIV-1 in infants and children
    • Archibald DW, Johnson JP, Nair P, Alger LS, Hebert CA, Davis E, et al. Detection of salivary immunoglobulin A antibodies to HIV-1 in infants and children. AIDS (1990) 4:417-20. doi:10.1097/00002030-199005000-00006
    • (1990) AIDS , vol.4 , pp. 417-420
    • Archibald, D.W.1    Johnson, J.P.2    Nair, P.3    Alger, L.S.4    Hebert, C.A.5    Davis, E.6
  • 105
    • 84857239125 scopus 로고    scopus 로고
    • Evaluation of salivary anti-Salmonella typhi lipopolysaccharide IgA ELISA for serodiagnosis of typhoid fever in children
    • Zaka-ur-Rab Z, Abqari S, Shahab T, Islam N, Shukla I. Evaluation of salivary anti-Salmonella typhi lipopolysaccharide IgA ELISA for serodiagnosis of typhoid fever in children. Arch Dis Child (2012) 97:236-8. doi:10.1136/adc.2011.300622
    • (2012) Arch Dis Child , vol.97 , pp. 236-238
    • Zaka-ur-Rab, Z.1    Abqari, S.2    Shahab, T.3    Islam, N.4    Shukla, I.5
  • 107
    • 79951895603 scopus 로고    scopus 로고
    • Has the use of molecular methods for the characterization of the human oral microbiome changed our understanding of the role of bacteria in the pathogenesis of periodontal disease?
    • Wade WG. Has the use of molecular methods for the characterization of the human oral microbiome changed our understanding of the role of bacteria in the pathogenesis of periodontal disease? J Clin Periodontol (2011) 38(Suppl 11):7-16. doi:10.1111/j.1600-051X.2010.01679.x
    • (2011) J Clin Periodontol , vol.38 , pp. 7-16
    • Wade, W.G.1
  • 109
    • 70449701839 scopus 로고    scopus 로고
    • Oral fluid testing for drugs of abuse
    • Bosker WM, Huestis MA. Oral fluid testing for drugs of abuse. Clin Chem (2009) 55:1910-31. doi:10.1373/clinchem.2008.108670
    • (2009) Clin Chem , vol.55 , pp. 1910-1931
    • Bosker, W.M.1    Huestis, M.A.2
  • 110
    • 84866123972 scopus 로고    scopus 로고
    • Rapid detection of illicit drugs in neat saliva using desorption/ionization on porous silicon
    • Guinan T, Ronci M, Kobus H, Voelcker NH. Rapid detection of illicit drugs in neat saliva using desorption/ionization on porous silicon. Talanta (2003) 99:791-8. doi:10.1016/j.talanta.2012.07.029
    • (2003) Talanta , vol.99 , pp. 791-798
    • Guinan, T.1    Ronci, M.2    Kobus, H.3    Voelcker, N.H.4
  • 111
    • 0037962246 scopus 로고    scopus 로고
    • Quantitation of cocaine and its major metabolites in human saliva using gas chromatography-positive chemical ionization-mass spectrometry (GC-PCI-MS)
    • Cámpora P, Bermejo AM, Tabernero MJ, Fernandez P. Quantitation of cocaine and its major metabolites in human saliva using gas chromatography-positive chemical ionization-mass spectrometry (GC-PCI-MS). J Anal Toxicol (2003) 27:270-4. doi:10.1093/jat/27.5.270
    • (2003) J Anal Toxicol , vol.27 , pp. 270-274
    • Cámpora, P.1    Bermejo, A.M.2    Tabernero, M.J.3    Fernandez, P.4
  • 112
    • 84885953518 scopus 로고    scopus 로고
    • LC-MS/MS of some atypical antipsychotics in human plasma, serum, oral fluid and haemolysed whole blood
    • Fisher DS, Patridge SJ, Handley SA, Couchman L, Morgan PE, Flanagan RJ. LC-MS/MS of some atypical antipsychotics in human plasma, serum, oral fluid and haemolysed whole blood. Forensic Sci Int (2013) 229:145-50. doi:10.1016/j.forsciint.2013.03.021
    • (2013) Forensic Sci Int , vol.229 , pp. 145-150
    • Fisher, D.S.1    Patridge, S.J.2    Handley, S.A.3    Couchman, L.4    Morgan, P.E.5    Flanagan, R.J.6


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